المؤلفون: Christopher Winter, X Dai, Christopher Ware, Jennifer O'Neil, Candia M. Kenific, John F. Reilly, J Gorenstein, George N. Nikov, Peter Strack, Nancy E. Kohl, Clay L. Efferson, KJ Leach, J Hardwick, Han Sang Kim, C Elbi, Jennifer Tammam, Giulio F. Draetta, Kaiko Kunii, T Look, Lht Van der Ploeg, J Zhao, Sudhir Rao, Pradip K. Majumder, Xianlu Qu, Martin L. Scott, L Bristow, Minilik Angagaw

المصدر: British Journal of Pharmacology. 158:1183-1195

مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, Cellular differentiation, Notch signaling pathway, Biology, Transplantation, Endocrinology, Mechanism of action, Intestinal mucosa, Apoptosis, Internal medicine, medicine, Cancer research, biology.protein, medicine.symptom, Signal transduction, Amyloid precursor protein secretase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::21d7e46cb8e8f8bf76892f0c3e8dcfb1
https://doi.org/10.1111/j.1476-5381.2009.00389.x

المؤلفون: Tammam J; Department of Oncology/Pharmacology, Merck Research Laboratories, Boston, MA 02115, USA., Ware C, Efferson C, O'Neil J, Rao S, Qu X, Gorenstein J, Angagaw M, Kim H, Kenific C, Kunii K, Leach KJ, Nikov G, Zhao J, Dai X, Hardwick J, Scott M, Winter C, Bristow L, Elbi C, Reilly JF, Look T, Draetta G, Van der Ploeg L, Kohl NE, Strack PR, Majumder PK

المصدر: British journal of pharmacology [Br J Pharmacol] 2009 Nov; Vol. 158 (5), pp. 1183-95. Date of Electronic Publication: 2009 Sep 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Amyloid Precursor Protein Secretases/*antagonists & inhibitors , Antineoplastic Agents/*pharmacology , Cyclic S-Oxides/*pharmacology , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy , Receptor, Notch1/*physiology , Thiadiazoles/*pharmacology, Amyloid beta-Peptides/blood ; Animals ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/adverse effects ; Apoptosis ; Cell Differentiation ; Cell Line, Tumor ; Colon/cytology ; Colon/drug effects ; Cyclic S-Oxides/administration & dosage ; Cyclic S-Oxides/adverse effects ; Down-Regulation ; Drug Administration Schedule ; Humans ; Intestinal Mucosa/cytology ; Intestinal Mucosa/drug effects ; Membrane Potential, Mitochondrial/drug effects ; Mice ; Mice, Nude ; Mitochondrial Proteins/biosynthesis ; Mitochondrial Proteins/genetics ; Neoplasm Transplantation ; Peptide Fragments/blood ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/metabolism ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Receptor, Notch1/genetics ; Signal Transduction ; Thiadiazoles/administration & dosage ; Thiadiazoles/adverse effects ; Transplantation, Heterologous

المؤلفون: Santos CA; Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Box G-B393, Providence, RI 02912, USA., Freedman BD, Leach KJ, Press DL, Scarpulla M, Mathiowitz E

المصدر: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 1999 Jun 28; Vol. 60 (1), pp. 11-22.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print Cited Medium: Print ISSN: 0168-3659 (Print) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE

مواضيع طبية MeSH: Dicarboxylic Acids* , Drug Delivery Systems*, Anhydrides/*chemistry , Decanoic Acids/*chemistry , Fumarates/*chemistry , Polymers/*chemistry, Calorimetry, Differential Scanning ; Chromatography, Gel ; Microspheres ; Spectroscopy, Fourier Transform Infrared ; X-Ray Diffraction

المؤلفون: Kyriakides TR; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., Leach KJ, Hoffman AS, Ratner BD, Bornstein P

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1999 Apr 13; Vol. 96 (8), pp. 4449-54.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Print ISSN: 0027-8424 (Print) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Foreign-Body Reaction/*physiopathology , Neovascularization, Pathologic/*physiopathology , Thrombospondins/*physiology, Animals ; Cell Adhesion Molecules/physiology ; Cells, Cultured ; Dimethylpolysiloxanes ; Extracellular Matrix/physiology ; Fibroblasts/cytology ; Fibroblasts/pathology ; Foreign-Body Reaction/pathology ; Mice ; Mice, Knockout ; Neovascularization, Pathologic/genetics ; Neovascularization, Pathologic/pathology ; Oxidation-Reduction ; Silicones ; Skin/cytology ; Skin/pathology ; Thrombospondins/deficiency ; Thrombospondins/genetics

المؤلفون: Leach KJ; Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, Rhode Island 02912, USA., Takahashi S, Mathiowitz E

المصدر: Biomaterials [Biomaterials] 1998 Nov; Vol. 19 (21), pp. 1981-8.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8100316 Publication Model: Print Cited Medium: Print ISSN: 0142-9612 (Print) Linking ISSN: 01429612 NLM ISO Abbreviation: Biomaterials Subsets: MEDLINE

مواضيع طبية MeSH: Implants, Experimental*, Biocompatible Materials/*pharmacokinetics , Decanoic Acids/*pharmacokinetics , Lactic Acid/*pharmacokinetics , Polyesters/*pharmacokinetics , Polymers/*pharmacokinetics, Animals ; Biocompatible Materials/chemistry ; Calorimetry, Differential Scanning ; Decanoic Acids/chemistry ; Drug Carriers ; Ethylene Oxide ; Lactic Acid/chemistry ; Microscopy, Electron, Scanning ; Microspheres ; Molecular Weight ; Polyesters/chemistry ; Polymers/chemistry ; Rats ; Rats, Sprague-Dawley ; Spectroscopy, Fourier Transform Infrared ; Sterilization

المؤلفون: Noble JS; DNA Laboratory, Clinical Genetics Unit, St. James's University Hospital, Leeds, UK., Leach KJ, Ellis LA, Taylor GR

المصدر: Methods in molecular medicine [Methods Mol Med] 1996; Vol. 5, pp. 185-204.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Humana Press Country of Publication: United States NLM ID: 101123138 Publication Model: Print Cited Medium: Print ISSN: 1543-1894 (Print) Linking ISSN: 15431894 NLM ISO Abbreviation: Methods Mol Med Subsets: PubMed not MEDLINE