المؤلفون: Yang, Minxiao, Shen, Hua, Flodby, Per, Koss, Michael D, Bassiouni, Rania, Liu, Yixin, Jashashvili, Tea, Neely, Aaron, Ogbolu, Ezuka, Castillo, Jonathan, Stueve, Theresa Ryan, Mullen, Daniel J, Ryan, Amy L, Carpten, John, Castaldi, Alessandra, Wallace, W Dean, Zhou, Beiyun, Borok, Zea, Marconett, Crystal N

المصدر: Cell Reports. 42(12)

مصطلحات موضوعية: Biological Sciences, Cancer, Lung, Rare Diseases, Lung Cancer, Aetiology, 2.1 Biological and endogenous factors, Good Health and Well Being, Animals, Mice, Adenocarcinoma of Lung, Cell Transformation, Neoplastic, Lung Neoplasms, Proto-Oncogene Proteins p21(ras), CP: Cancer, KRT8(+) intermediate cell states, Kras(G12D) signaling, alveolar epithelial cells, cell of origin, lung cancer, oncogenesis, spatial transcriptomic sequencing, KrasG12D signaling, TGF&beta, signaling, Epithelial-mesenchymal transition (, EMT), Krt8+, intermediate cell state, Biochemistry and Cell Biology, Medical Physiology, Biological sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0nv5z5qx

المؤلفون: Geou-Yarh Liou, Crystal J. Byrd, Peter Storz, Justin K. Messex

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 9, p 4726 (2024)

مصطلحات موضوعية: KRASG12D, CCL9, PDAC initiation, ROS, MMP14, MMP3, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1422-0067/25/9/4726; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067

URL الوصول: https://doaj.org/article/3a1d94349e5e4a25bc7033b7e23731e0

المؤلفون: Liang, Fanglin, Kang, Zhengzhong, Sun, Xianqiang^{Aff2, IDs10822023004981_cor3}, Chen, Jiao, Duan, Xuemin, He, Hu^{Aff3, IDs10822023004981_cor6}, Cheng, Jianxin^{Aff1, IDs10822023004981_cor7}

المصدر: Journal of Computer-Aided Molecular Design: Incorporating Perspectives in Drug Discovery and Design. 37(3):157-166

المؤلفون: Zhenya Du, Gao Tu, Yaguo Gong, Xiangzheng Fu, Qibiao Wu, Guankui Long

المصدر: Molecules, Vol 29, Iss 6, p 1229 (2024)

مصطلحات موضوعية: KRASG12D, noncovalent inhibitor, virtual screening, molecular dynamics, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/29/6/1229; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/0335af92a77647459f2493b39bc49576

المؤلفون: Matthias Drosten, Mariano Barbacid

المصدر: Molecular Oncology, Vol 16, Iss 22, Pp 3911-3915 (2022)

مصطلحات موضوعية: colorectal cancer, combination therapies, KRASG12D, noncovalent binding, pancreatic ductal adenocarcinoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

URL الوصول: https://doaj.org/article/7f0432a4b2624f96b68c1f2aa36ab0f6

المؤلفون: Schofield, Heather K, Tandon, Manuj, Park, Min-Jung, Halbrook, Christopher J, Ramakrishnan, Sadeesh K, Kim, Esther C, Shi, Jiaqi, Omary, M Bishr, Shah, Yatrik M, Esni, Farzad, di Magliano, Marina Pasca

المصدر: Cellular and Molecular Gastroenterology and Hepatology. 5(2)

مصطلحات موضوعية: Biological Sciences, Biomedical and Clinical Sciences, Genetics, Digestive Diseases, Cancer, Pancreatic Cancer, Rare Diseases, 2.1 Biological and endogenous factors, Aetiology, Chronic Pancreatitis, ER, endoplasmic reticulum, HIF2α, HIF2α, hypoxia-inducible factor 2α, Hypoxia, KC, Pdx1-Cre, LSLKrasG12D, KrasG12D, MCN, mucinous cystic neoplasm, Mucinous Cystic Neoplasm, PanIN, pancreatic intraepithelial neoplasia, Pancreas, UPR, unfolded protein response, VHL, von Hippel-Lindau, qPCR, quantitative polymerase chain reaction, Biochemistry and cell biology, Clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/20k3v62t

المؤلفون: Yuting Wang, Hai Zhang, Jindong Li, Miao-Miao Niu, Yang Zhou, Yuanqian Qu

المصدر: Frontiers in Pharmacology, Vol 13 (2022)

مصطلحات موضوعية: KRASG12D, pancreatic cancer, inhibitor, virtual screening, biological evaluation, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.1094887/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/2eea180b562244dfb38b09056071bd30

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