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1
المؤلفون: Hannu Raunio, Aline Horling, Kaisa A. Salminen, Peter Imming, Achim Meyer, Tuomo Laitinen, Minna Rahnasto-Rilla, Maija Lahtela-Kakkonen, Antti Poso, Raija Väänänen
المصدر: Drug Metabolism and Disposition. 43:1891-1904
مصطلحات موضوعية: Quantitative structure–activity relationship, Time Factors, In silico, Quantitative Structure-Activity Relationship, Pharmaceutical Science, Pharmacology, chemistry.chemical_compound, Alkaloids, Berberine, medicine, Humans, Computer Simulation, Isoquinoline, chemistry.chemical_classification, Plant Extracts, Bulbocapnine, Isoquinolines, Noscapine, Cytochrome P-450 CYP2C19, Canadine, Enzyme, chemistry, Biochemistry, Cytochrome P-450 CYP2C19 Inhibitors, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1471c9b1aba77ea2a6d539d25badbe6
https://doi.org/10.1124/dmd.115.065755 -
2
المؤلفون: Carsten Wittekindt, Niina Tani, Minna Rahnasto-Rilla, Kaisa A. Salminen, Jenna Koskiranta, Riina Ollakka, Anniina Ritvanen, Risto O. Juvonen, Hannu Raunio
المصدر: European Journal of Medicinal Chemistry. 47:270-277
مصطلحات موضوعية: Models, Molecular, Antifungal Agents, Protein Conformation, Stereochemistry, Saccharomyces cerevisiae, Drug Evaluation, Preclinical, Sterol 14-Demethylase, User-Computer Interface, Candida albicans, Nitriles, Drug Discovery, Humans, Homology modeling, Enzyme Inhibitors, Pharmacology, chemistry.chemical_classification, biology, Chemistry, Organic Chemistry, Active site, Cytochrome P450, General Medicine, biology.organism_classification, Liver, Biochemistry, Docking (molecular), Drug Design, biology.protein, Azole, Pharmacophore
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3
المؤلفون: Laura E. Korhonen, Minna Rahnasto, Peter Imming, Kaisa A. Salminen, Risto O. Juvonen, Achim Meyer, Hannu Raunio, Lenka Jerabkova
المصدر: Phytomedicine. 18:533-538
مصطلحات موضوعية: CYP2B6, Herb-Drug Interactions, Pharmaceutical Science, Pharmacology, chemistry.chemical_compound, Alkaloids, Papaveraceae, Drug Discovery, Cytochrome P-450 Enzyme Inhibitors, Humans, heterocyclic compounds, Enzyme Inhibitors, Isoquinoline, CYP2A6, chemistry.chemical_classification, biology, CYP3A4, Plant Extracts, organic chemicals, CYP1A2, Cytochrome P450, Isoquinolines, Enzyme, Complementary and alternative medicine, Biochemistry, chemistry, biology.protein, Molecular Medicine
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4
المؤلفون: Seppo Auriola, Jarkko I. Venäläinen, Kaisa A. Salminen, Markku Pasanen, Jukka Leppänen, Risto O. Juvonen, Hannu Raunio
المصدر: Drug Metabolism and Disposition. 39:412-418
مصطلحات موضوعية: Ticlopidine, Kinetics, Drug Evaluation, Preclinical, Pharmaceutical Science, chemistry.chemical_compound, Non-competitive inhibition, Isoniazid, medicine, Humans, Drug Interactions, Enzyme Inhibitors, Fluorescein, Enzyme Assays, Fluorescent Dyes, Pharmacology, chemistry.chemical_classification, Chromatography, biology, Chemistry, Tranylcypromine, Cytochrome P450, Substrate (chemistry), Hydrogen-Ion Concentration, Drug interaction, Fluoresceins, Recombinant Proteins, Cytochrome P-450 CYP2C19, Spectrometry, Fluorescence, Enzyme, Biochemistry, Biocatalysis, biology.protein, Aryl Hydrocarbon Hydroxylases, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b5b44b062f613af007dcb63298cba0
https://doi.org/10.1124/dmd.110.036376 -
5
المؤلفون: Kaisa A. Salminen, Hannu Raunio, Peter Imming, Achim Meyer
المصدر: Drug metabolism and disposition: the biological fate of chemicals. 39(12)
مصطلحات موضوعية: Pharmacology, chemistry.chemical_classification, Benzophenanthridines, Aporphines, Berberine, Stereochemistry, Bulbocapnine, Berberine Alkaloids, Pharmaceutical Science, CYP2C19, In vitro, Canadine, Absorbance, Cytochrome P-450 CYP2C19, chemistry.chemical_compound, Enzyme, chemistry, Protopine, Humans, Aryl Hydrocarbon Hydroxylases, Isoquinoline, Enzyme Inhibitors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b132dacca2cb411379dc8bfc5c7928
https://pubmed.ncbi.nlm.nih.gov/21908684 -
6
المؤلفون: Kaisa A. Salminen, Hannu Raunio, Minna Rahnasto, Risto O. Juvonen, Jukka Leppänen, Maija Lahtela-Kakkonen, Antti Poso, Carsten Wittekindt
المصدر: Bioorganicmedicinal chemistry. 19(23)
مصطلحات موضوعية: Models, Molecular, Clinical Biochemistry, Drug Evaluation, Preclinical, Pharmaceutical Science, Quantitative Structure-Activity Relationship, Pharmacology, Biochemistry, Nicotine, Cytochrome P-450 CYP2A6, Drug Discovery, medicine, Humans, Enzyme Inhibitors, CYP2A6, Molecular Biology, Smoking Reduction, chemistry.chemical_classification, Virtual screening, Organic Chemistry, Kinetics, Enzyme, chemistry, Molecular Medicine, Identification (biology), Aryl Hydrocarbon Hydroxylases, medicine.drug