المؤلفون: Buescher, JM, Antoniewicz, MR, Boros, LG, Burgess, SC, Brunengraber, H, Clish, CB, DeBerardinis, RJ, Feron, O, Frezza, C, Ghesquiere, B, Gottlieb, E, Hiller, K, Jones, RG, Kamphorst, JJ, Kibbey, RG, Kimmelman, AC, Locasale, JW, Lunt, SY, Maddocks, ODK, Malloy, C, Metallo, CM, Meuillet, EJ, Munger, J, Nöh, K, Rabinowitz, JD, Ralser, M, Sauer, U, Stephanopoulos, G, St-Pierre, J, Tennant, DA, Wittmann, C, Vander Heiden, MG, Vazquez, A, Vousden, K, Young, JD, Zamboni, N, Fendt, SM

المصدر: Buescher, JM; Antoniewicz, MR; Boros, LG; Burgess, SC; Brunengraber, H; Clish, CB; et al.(2015). A roadmap for interpreting13C metabolite labeling patterns from cells. Current Opinion in Biotechnology, 34, 189-201. doi: 10.1016/j.copbio.2015.02.003. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/5fr4f1fn

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______325::4ec18484cc9545e4a28cce972d8bf60d
http://www.escholarship.org/uc/item/5fr4f1fn

المؤلفون: Dorrani M; Olaris, Inc., 175 Crossing Boulevard Suite 410, Framingham, MA 01702, USA., Zhao J; Olaris, Inc., 175 Crossing Boulevard Suite 410, Framingham, MA 01702, USA., Bekhti N; Olaris, Inc., 175 Crossing Boulevard Suite 410, Framingham, MA 01702, USA., Trimigno A; Olaris, Inc., 175 Crossing Boulevard Suite 410, Framingham, MA 01702, USA., Min S; Seoul National University Hospital, 101, Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea., Ha J; Seoul National University Hospital, 101, Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea., Han A; Seoul National University Hospital, 101, Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea., O'Day E; Olaris, Inc., 175 Crossing Boulevard Suite 410, Framingham, MA 01702, USA., Kamphorst JJ; Olaris, Inc., 175 Crossing Boulevard Suite 410, Framingham, MA 01702, USA.

المصدر: Metabolites [Metabolites] 2024 May 11; Vol. 14 (5). Date of Electronic Publication: 2024 May 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101578790 Publication Model: Electronic Cited Medium: Print ISSN: 2218-1989 (Print) Linking ISSN: 22181989 NLM ISO Abbreviation: Metabolites Subsets: PubMed not MEDLINE

المؤلفون: Cousins A; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Olivares O; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Markert E; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.; Cancer Research UK Beatson Institute, Glasgow, UK., Manoharan A; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Bubnova X; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Bresolin S; Department of Women's and Children's Health, University of Padova, Padova, Italy., Degn M; Department of Pediatrics and Adolescent Medicine, The Juliane Marie Centre, The University Hospital Rigshospitalet, Copenhagen, Denmark., Li Z; VIVA-NUS Centre for Translational Research in Acute Leukaemia, Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117599, Singapore., Silvestri D; Center of Biostatistics for Clinical Epidemiology, Department of Health Science, University of Milano-Bicocca, Milano, Italy., McGregor G; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.; Cancer Research UK Beatson Institute, Glasgow, UK., Tumanov S; Cancer Research UK Beatson Institute, Glasgow, UK., Sumpton D; Cancer Research UK Beatson Institute, Glasgow, UK., Kamphorst JJ; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.; Cancer Research UK Beatson Institute, Glasgow, UK., Michie AM; Paul O'Gorman Leukaemia Research Centre, School of Cancer Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Herzyk P; Glasgow Polyomics, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.; Institute of Molecular, Cell and Systems Biology, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Valsecchi MG; Center of Biostatistics for Clinical Epidemiology, Department of Health Science, University of Milano-Bicocca, Milano, Italy., Yeoh AE; VIVA-NUS Centre for Translational Research in Acute Leukaemia, Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117599, Singapore.; VIVA-University Children's Cancer Centre, Khoo Teck Puat-National University Children's Medical Institute, National University Hospital, National University Health System, Singapore, 119228, Singapore., Schmiegelow K; Department of Pediatrics and Adolescent Medicine, The Juliane Marie Centre, The University Hospital Rigshospitalet, Copenhagen, Denmark.; Institute of Clinical Medicine, Faculty of Medicine, University of Copenhagen and Juliane Marie Centre, the University Hospital Rigshospitalet, Copenhagen, Denmark., Te Kronnie G; Department of Molecular Medicine, University of Padova, Padova, Italy., Gottlieb E; The Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel., Halsey C; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK. Chris.Halsey@glasgow.ac.uk.

المصدر: Leukemia [Leukemia] 2022 Dec; Vol. 36 (12), pp. 2903-2907. Date of Electronic Publication: 2022 Oct 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE

مواضيع طبية MeSH: Precursor Cell Lymphoblastic Leukemia-Lymphoma*/genetics , Central Nervous System Neoplasms*, Humans ; Up-Regulation ; Biosynthetic Pathways ; Central Nervous System ; Cholesterol

المؤلفون: Kay EJ; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Paterson K; Centre for Microsystems and Photonics, EEE Department, University of Strathclyde, Glasgow, UK., Riera-Domingo C; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology (CCB), VIB, Leuven, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Department of Oncology, KU Leuven, Leuven, Belgium., Sumpton D; Cancer Research UK Beatson Institute, Glasgow, UK., Däbritz JHM; Cancer Research UK Beatson Institute, Glasgow, UK., Tardito S; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Boldrini C; Cancer Research UK Beatson Institute, Glasgow, UK., Hernandez-Fernaud JR; Cancer Research UK Beatson Institute, Glasgow, UK., Athineos D; Cancer Research UK Beatson Institute, Glasgow, UK., Dhayade S; Cancer Research UK Beatson Institute, Glasgow, UK., Stepanova E; Translational Control and Metabolism, German Cancer Research Center (DKFZ), Heidelberg, Germany., Gjerga E; Heidelberg University, Faculty of Medicine, Institute for Computational Biomedicine, Bioquant, Heidelberg, Germany.; RWTH Aachen University, Faculty of Medicine, Joint Research Centre for Computational Biomedicine (JRC-COMBINE), Aachen, Germany., Neilson LJ; Cancer Research UK Beatson Institute, Glasgow, UK., Lilla S; Cancer Research UK Beatson Institute, Glasgow, UK., Hedley A; Cancer Research UK Beatson Institute, Glasgow, UK., Koulouras G; Cancer Research UK Beatson Institute, Glasgow, UK., McGregor G; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Jamieson C; Department of Pure and Applied Chemistry, Thomas Graham Building, University of Strathclyde, Glasgow, UK., Johnson RM; Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada., Park M; Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada.; Department of Medicine, McGill University, Montreal, Quebec, Canada.; Department of Oncology, McGill University, Montreal, Quebec, Canada., Kirschner K; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Miller C; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Kamphorst JJ; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Loayza-Puch F; Translational Control and Metabolism, German Cancer Research Center (DKFZ), Heidelberg, Germany., Saez-Rodriguez J; Heidelberg University, Faculty of Medicine, Institute for Computational Biomedicine, Bioquant, Heidelberg, Germany.; RWTH Aachen University, Faculty of Medicine, Joint Research Centre for Computational Biomedicine (JRC-COMBINE), Aachen, Germany., Mazzone M; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology (CCB), VIB, Leuven, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Department of Oncology, KU Leuven, Leuven, Belgium., Blyth K; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Zagnoni M; Centre for Microsystems and Photonics, EEE Department, University of Strathclyde, Glasgow, UK., Zanivan S; Cancer Research UK Beatson Institute, Glasgow, UK. s.zanivan@beatson.gla.ac.uk.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK. s.zanivan@beatson.gla.ac.uk.

المصدر: Nature metabolism [Nat Metab] 2022 Aug; Vol. 4 (8), pp. 1084.

نوع المنشور: Published Erratum

بيانات الدورية: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Kay EJ; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Paterson K; Centre for Microsystems and Photonics, EEE Department, University of Strathclyde, Glasgow, UK., Riera-Domingo C; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology (CCB), VIB, Leuven, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Department of Oncology, KU Leuven, Leuven, Belgium., Sumpton D; Cancer Research UK Beatson Institute, Glasgow, UK., Däbritz JHM; Cancer Research UK Beatson Institute, Glasgow, UK., Tardito S; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Boldrini C; Cancer Research UK Beatson Institute, Glasgow, UK., Hernandez-Fernaud JR; Cancer Research UK Beatson Institute, Glasgow, UK., Athineos D; Cancer Research UK Beatson Institute, Glasgow, UK., Dhayade S; Cancer Research UK Beatson Institute, Glasgow, UK., Stepanova E; Translational Control and Metabolism, German Cancer Research Center (DKFZ), Heidelberg, Germany., Gjerga E; Heidelberg University, Faculty of Medicine, Institute for Computational Biomedicine, Bioquant, Heidelberg, Germany.; RWTH Aachen University, Faculty of Medicine, Joint Research Centre for Computational Biomedicine (JRC-COMBINE), Aachen, Germany., Neilson LJ; Cancer Research UK Beatson Institute, Glasgow, UK., Lilla S; Cancer Research UK Beatson Institute, Glasgow, UK., Hedley A; Cancer Research UK Beatson Institute, Glasgow, UK., Koulouras G; Cancer Research UK Beatson Institute, Glasgow, UK., McGregor G; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Jamieson C; Department of Pure and Applied Chemistry, Thomas Graham Building, University of Strathclyde, Glasgow, UK., Johnson RM; Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada., Park M; Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada.; Department of Medicine, McGill University, Montreal, Quebec, Canada.; Department of Oncology, McGill University, Montreal, Quebec, Canada., Kirschner K; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Miller C; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Kamphorst JJ; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Loayza-Puch F; Translational Control and Metabolism, German Cancer Research Center (DKFZ), Heidelberg, Germany., Saez-Rodriguez J; Heidelberg University, Faculty of Medicine, Institute for Computational Biomedicine, Bioquant, Heidelberg, Germany.; RWTH Aachen University, Faculty of Medicine, Joint Research Centre for Computational Biomedicine (JRC-COMBINE), Aachen, Germany., Mazzone M; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology (CCB), VIB, Leuven, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Department of Oncology, KU Leuven, Leuven, Belgium., Blyth K; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Zagnoni M; Centre for Microsystems and Photonics, EEE Department, University of Strathclyde, Glasgow, UK., Zanivan S; Cancer Research UK Beatson Institute, Glasgow, UK. s.zanivan@beatson.gla.ac.uk.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK. s.zanivan@beatson.gla.ac.uk.

المصدر: Nature metabolism [Nat Metab] 2022 Jun; Vol. 4 (6), pp. 693-710. Date of Electronic Publication: 2022 Jun 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms*/metabolism , Cancer-Associated Fibroblasts*/metabolism , Cancer-Associated Fibroblasts*/pathology, Pyrroline Carboxylate Reductases/*metabolism, Carcinogenesis/metabolism ; Carcinogenesis/pathology ; Collagen/metabolism ; Extracellular Matrix/metabolism ; Female ; Glutamine/metabolism ; Humans ; Proline ; delta-1-Pyrroline-5-Carboxylate Reductase

المؤلفون: Blomme A; CRUK Beatson Institute, Garscube Estate, Glasgow, UK., Peter C; CRUK Beatson Institute, Garscube Estate, Glasgow, UK., Mui E; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, UK., Rodriguez Blanco G; CRUK Beatson Institute, Garscube Estate, Glasgow, UK., An N; Laboratory of Cancer Signaling, GIGA-Institute, University of Liège, Liège, Belgium., Mason LM; School of Engineering, University of Glasgow, Glasgow, UK., Jamieson LE; Centre for Molecular Nanometrology, Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, Glasgow, UK., McGregor GH; CRUK Beatson Institute, Garscube Estate, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, UK., Lilla S; CRUK Beatson Institute, Garscube Estate, Glasgow, UK., Ntala C; CRUK Beatson Institute, Garscube Estate, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, UK., Patel R; CRUK Beatson Institute, Garscube Estate, Glasgow, UK., Thiry M; GIGA-Neurosciences, Unit of Cell and Tissue Biology, University of Liège, Liège, Belgium., Kung SHY; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.; Vancouver Prostate Centre, Vancouver, BC, Canada., Leclercq M; Laboratory of Cancer Signaling, GIGA-Institute, University of Liège, Liège, Belgium., Ford CA; CRUK Beatson Institute, Garscube Estate, Glasgow, UK., Rushworth LK; CRUK Beatson Institute, Garscube Estate, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, UK., McGarry DJ; CRUK Beatson Institute, Garscube Estate, Glasgow, UK., Mason S; CRUK Beatson Institute, Garscube Estate, Glasgow, UK., Repiscak P; CRUK Beatson Institute, Garscube Estate, Glasgow, UK., Nixon C; CRUK Beatson Institute, Garscube Estate, Glasgow, UK., Salji MJ; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, UK., Markert E; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, UK., MacKay GM; CRUK Beatson Institute, Garscube Estate, Glasgow, UK., Kamphorst JJ; CRUK Beatson Institute, Garscube Estate, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, UK., Graham D; Centre for Molecular Nanometrology, Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, Glasgow, UK., Faulds K; Centre for Molecular Nanometrology, Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, Glasgow, UK., Fazli L; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.; Vancouver Prostate Centre, Vancouver, BC, Canada., Gleave ME; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.; Vancouver Prostate Centre, Vancouver, BC, Canada., Avezov E; UK Dementia Research Institute at University of Cambridge, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Edwards J; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, UK., Yin H; School of Engineering, University of Glasgow, Glasgow, UK., Sumpton D; CRUK Beatson Institute, Garscube Estate, Glasgow, UK., Blyth K; CRUK Beatson Institute, Garscube Estate, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, UK., Close P; Laboratory of Cancer Signaling, GIGA-Institute, University of Liège, Liège, Belgium., Murphy DJ; CRUK Beatson Institute, Garscube Estate, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, UK., Zanivan S; CRUK Beatson Institute, Garscube Estate, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, UK., Leung HY; CRUK Beatson Institute, Garscube Estate, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, UK.

المصدر: EMBO molecular medicine [EMBO Mol Med] 2022 Mar 07; Vol. 14 (3), pp. e14764. Date of Electronic Publication: 2022 Jan 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE

مواضيع طبية MeSH: Androgen Antagonists*/pharmacology , Androgen Antagonists*/therapeutic use , Prostatic Neoplasms, Castration-Resistant*/drug therapy , Prostatic Neoplasms, Castration-Resistant*/pathology, Gene Expression Regulation, Neoplastic ; Humans ; Lipid Metabolism ; Male

المؤلفون: Savino AM; Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; Sheba Medical Center, Ramat Gan, Israel.; Molecular Pharmacology Program, Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Fernandes SI; The Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel., Olivares O; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Zemlyansky A; Schneider Children's Medical Center of Israel, Petach Tiqva, Israel., Cousins A; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Markert EK; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.; Cancer Research UK Beatson Institute, Glasgow, UK., Barel S; Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; Sheba Medical Center, Ramat Gan, Israel., Geron I; Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; Sheba Medical Center, Ramat Gan, Israel., Frishman L; Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; Sheba Medical Center, Ramat Gan, Israel., Birger Y; Sheba Medical Center, Ramat Gan, Israel.; Schneider Children's Medical Center of Israel, Petach Tiqva, Israel., Eckert C; Charite University, Berlin, Germany., Tumanov S; Cancer Research UK Beatson Institute, Glasgow, UK., MacKay G; Cancer Research UK Beatson Institute, Glasgow, UK., Kamphorst JJ; Cancer Research UK Beatson Institute, Glasgow, UK.; Rheos Medicines, Cambridge, MA, USA., Herzyk P; Glasgow Polyomics, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.; Institute of Molecular, Cell and Systems Biology, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Fernández-García J; The Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel., Abramovich I; The Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel., Mor I; The Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel., Bardini M; Centro Ricerca Tettamanti, Fondazione MBBM, Universita degli Studi di Milano-Bicocca, Monza, Italy., Barin E; Molecular Pharmacology Program, Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Janaki-Raman S; Donald B. and Catherine C. Marron Cancer Metabolism Center, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Cross JR; Donald B. and Catherine C. Marron Cancer Metabolism Center, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kharas MG; Molecular Pharmacology Program, Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Gottlieb E; The Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. e.gottlieb@technion.ac.il., Izraeli S; Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. sizraeli@gmail.com.; Sheba Medical Center, Ramat Gan, Israel. sizraeli@gmail.com.; Schneider Children's Medical Center of Israel, Petach Tiqva, Israel. sizraeli@gmail.com.; Beckman Research Institute, City of Hope, Duarte, CA, USA. sizraeli@gmail.com., Halsey C; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK. chris.halsey@glasgow.ac.uk.

المصدر: Nature cancer [Nat Cancer] 2020 Oct; Vol. 1 (10), pp. 998-1009. Date of Electronic Publication: 2020 Sep 28.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer

مواضيع طبية MeSH: Precursor Cell Lymphoblastic Leukemia-Lymphoma* , Stearoyl-CoA Desaturase*/genetics, Central Nervous System/metabolism ; Humans ; Lipogenesis ; Tumor Microenvironment

المؤلفون: Blomme A; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Ford CA; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Mui E; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Patel R; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Ntala C; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Jamieson LE; Centre for Molecular Nanometrology, Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, 99 George Street, Glasgow, G1 1RD, UK., Planque M; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, 3000, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat 49, 3000, Leuven, Belgium., McGregor GH; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Peixoto P; Univ. Bourgogne Franche-Comté, INSERM, EFS BFC, UMR1098, Interactions Hôte-Greffon-Tumeur/Ingénierie Cellulaire et Génique, 25000, Besançon, France.; EPIGENExp (EPIgenetics and GENe EXPression Technical Platform), Besançon, France.; DIMACELL Dispositif Interrégional d'Imagerie Cellulaire, Dijon, France., Hervouet E; Univ. Bourgogne Franche-Comté, INSERM, EFS BFC, UMR1098, Interactions Hôte-Greffon-Tumeur/Ingénierie Cellulaire et Génique, 25000, Besançon, France.; EPIGENExp (EPIgenetics and GENe EXPression Technical Platform), Besançon, France.; DIMACELL Dispositif Interrégional d'Imagerie Cellulaire, Dijon, France., Nixon C; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Salji M; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Gaughan L; Northern Institute for Cancer Research, The Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK., Markert E; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Repiscak P; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Sumpton D; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Blanco GR; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Lilla S; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Kamphorst JJ; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Graham D; Centre for Molecular Nanometrology, Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, 99 George Street, Glasgow, G1 1RD, UK., Faulds K; Centre for Molecular Nanometrology, Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, 99 George Street, Glasgow, G1 1RD, UK., MacKay GM; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Fendt SM; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, 3000, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat 49, 3000, Leuven, Belgium., Zanivan S; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Leung HY; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK. h.leung@beatson.gla.ac.uk.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK. h.leung@beatson.gla.ac.uk.

المصدر: Nature communications [Nat Commun] 2020 May 19; Vol. 11 (1), pp. 2508. Date of Electronic Publication: 2020 May 19.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Lipid Metabolism*, Oxidoreductases Acting on CH-CH Group Donors/*metabolism , Prostatic Neoplasms, Castration-Resistant/*enzymology, Androgen Receptor Antagonists/administration & dosage ; Disease Progression ; Homeostasis ; Humans ; Male ; Mitochondria/enzymology ; Mitochondria/genetics ; Oxidoreductases Acting on CH-CH Group Donors/genetics ; Phospholipids/metabolism ; Prostate/enzymology ; Prostate/metabolism ; Prostatic Neoplasms, Castration-Resistant/drug therapy ; Prostatic Neoplasms, Castration-Resistant/genetics ; Receptors, Androgen/genetics ; Receptors, Androgen/metabolism

المؤلفون: Fu A; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Alvarez-Perez JC; Diabetes, Obesity and Metabolism Institute, Department of Medicine, Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Avizonis D; Rosalind and Morris Goodman Cancer Center Metabolomics Core, Montreal, Canada., Kin T; Clinical Islet Transplant Program, Department of Surgery, University of Alberta, Edmonton, Canada., Ficarro SB; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Blais Proteomics Center, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Choi DW; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Karakose E; Diabetes, Obesity and Metabolism Institute, Department of Medicine, Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Badur MG; Rheos Medicines, Cambridge, MA, USA., Evans L; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Rosselot C; Diabetes, Obesity and Metabolism Institute, Department of Medicine, Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bridon G; Rosalind and Morris Goodman Cancer Center Metabolomics Core, Montreal, Canada., Bird GH; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Seo HS; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA., Dhe-Paganon S; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA., Kamphorst JJ; Rheos Medicines, Cambridge, MA, USA., Stewart AF; Diabetes, Obesity and Metabolism Institute, Department of Medicine, Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA., James Shapiro AM; Clinical Islet Transplant Program, Department of Surgery, University of Alberta, Edmonton, Canada., Marto JA; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Blais Proteomics Center, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Walensky LD; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Jones RG; Metabolic and Nutritional Programming, Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, MI, USA., Garcia-Ocana A; Diabetes, Obesity and Metabolism Institute, Department of Medicine, Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Danial NN; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA. nika_danial@dfci.harvard.edu.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. nika_danial@dfci.harvard.edu.; Department of Medicine, Harvard Medical School, Boston, MA, USA. nika_danial@dfci.harvard.edu.

المصدر: Nature metabolism [Nat Metab] 2020 May; Vol. 2 (5), pp. 432-446. Date of Electronic Publication: 2020 May 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: MEDLINE

مواضيع طبية MeSH: Arginine/*metabolism , Glucose/*metabolism , Glucose/*pharmacology , Inflammation/*prevention & control , Insulin-Secreting Cells/*drug effects , Urea/*metabolism , Urea Cycle Disorders, Inborn/*pathology, Adolescent ; Adult ; Aged ; Aspartic Acid/metabolism ; Cell Survival ; Citric Acid Cycle/drug effects ; Female ; Humans ; Inflammation/pathology ; Insulin-Secreting Cells/pathology ; Male ; Metabolomics ; Middle Aged ; Nitric Oxide/metabolism ; Pyruvate Carboxylase/metabolism ; Urea Cycle Disorders, Inborn/metabolism ; Young Adult

المؤلفون: Michalopoulou E; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow G61 1QH, UK., Auciello FR; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow G61 1QH, UK., Bulusu V; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow G61 1QH, UK., Strachan D; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK., Campbell AD; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK., Tait-Mulder J; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow G61 1QH, UK., Karim SA; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK., Morton JP; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow G61 1QH, UK., Sansom OJ; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow G61 1QH, UK., Kamphorst JJ; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow G61 1QH, UK. Electronic address: jurre.kamphorst@glasgow.ac.uk.

المصدر: Cell reports [Cell Rep] 2020 Feb 25; Vol. 30 (8), pp. 2729-2742.e4.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Drug Resistance, Neoplasm* , Pinocytosis*, Pancreatic Neoplasms/*pathology , TOR Serine-Threonine Kinases/*antagonists & inhibitors, Adenocarcinoma/pathology ; Animals ; Carcinoma, Pancreatic Ductal/pathology ; Cell Death ; Cell Line, Tumor ; Cell Proliferation ; Lysosomes/metabolism ; Mechanistic Target of Rapamycin Complex 2/metabolism ; Mice, Inbred C57BL ; Models, Biological ; PTEN Phosphohydrolase/metabolism ; Pancreatic Neoplasms/metabolism ; Phosphorylation ; Phosphoserine/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins p21(ras)/metabolism ; Signal Transduction ; TOR Serine-Threonine Kinases/metabolism ; Up-Regulation