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1دورية أكاديمية
المؤلفون: Whitehead GS; Immunogenetics Group, Immunity, Inflammation and Disease Laboratory, NIEHS, National Institutes of Health, Research Triangle Park, Durham, North Carolina 27709, United States., Karcz TP; Immunogenetics Group, Immunity, Inflammation and Disease Laboratory, NIEHS, National Institutes of Health, Research Triangle Park, Durham, North Carolina 27709, United States.; Jagiellonian University Medical College, 30-688 Krakoẃ, Poland., Tosh DK; Laboratory of Bioorganic Chemistry, Molecular Recognition Section, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, United States., Jung YH; Laboratory of Bioorganic Chemistry, Molecular Recognition Section, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, United States., Wen Z; Laboratory of Bioorganic Chemistry, Molecular Recognition Section, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, United States., Campbell RG; Laboratory of Bioorganic Chemistry, Molecular Recognition Section, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, United States., Gopinatth V; Laboratory of Bioorganic Chemistry, Molecular Recognition Section, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, United States., Gao ZG; Laboratory of Bioorganic Chemistry, Molecular Recognition Section, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, United States., Jacobson KA; Laboratory of Bioorganic Chemistry, Molecular Recognition Section, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, United States., Cook DN; Immunogenetics Group, Immunity, Inflammation and Disease Laboratory, NIEHS, National Institutes of Health, Research Triangle Park, Durham, North Carolina 27709, United States.
المصدر: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2022 Oct 05; Vol. 5 (10), pp. 973-984. Date of Electronic Publication: 2022 Oct 05 (Print Publication: 2022).
نوع المنشور: Journal Article
بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101721411 Publication Model: eCollection Cited Medium: Internet ISSN: 2575-9108 (Electronic) Linking ISSN: 25759108 NLM ISO Abbreviation: ACS Pharmacol Transl Sci Subsets: PubMed not MEDLINE
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2دورية أكاديمية
المؤلفون: Wen Z; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Salmaso V; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Jung YH; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Phung NB; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Gopinatth V; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Shah Q; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Patterson AT; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Randle JCR; Random Walk Ventures, LLC, 108 Lincoln Street Unit 6B, Boston, Massachusetts 02111, United States., Chen Z; Department of Pharmacology and Physiology and the Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University School of Medicine, 1402 South Grand Boulevard, St. Louis, Missouri 63104, United States., Salvemini D; Department of Pharmacology and Physiology and the Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University School of Medicine, 1402 South Grand Boulevard, St. Louis, Missouri 63104, United States., Lieberman DI; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Whitehead GS; Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, United States., Karcz TP; Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, United States., Cook DN; Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, United States., Jacobson KA; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States.
المصدر: Journal of medicinal chemistry [J Med Chem] 2022 Feb 24; Vol. 65 (4), pp. 3434-3459. Date of Electronic Publication: 2022 Feb 03.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
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3دورية أكاديمية
المؤلفون: Jain S; Molecular Recognition Section and., Pydi SP; Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland, USA., Jung YH; Molecular Recognition Section and., Scortichini M; Molecular Recognition Section and., Kesner EL; Molecular Recognition Section and., Karcz TP; Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA., Cook DN; Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA., Gavrilova O; Mouse Metabolism Core, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland, USA., Wess J; Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland, USA., Jacobson KA; Molecular Recognition Section and.
المصدر: JCI insight [JCI Insight] 2021 May 24; Vol. 6 (10). Date of Electronic Publication: 2021 May 24.
نوع المنشور: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE
مواضيع طبية MeSH: Glucose/*metabolism , Lipolysis/*drug effects , Purinergic P2Y Receptor Antagonists/*pharmacology , Receptors, Purinergic P2Y/*metabolism, Adipocytes/cytology ; Adipocytes/drug effects ; Adipocytes/metabolism ; Adipose Tissue/cytology ; Adipose Tissue/drug effects ; Adipose Tissue/metabolism ; Animals ; Male ; Mice ; Mice, Inbred C57BL
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4دورية أكاديمية
المؤلفون: Jung YH; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Salmaso V; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Wen Z; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Bennett JM; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Phung NB; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Lieberman DI; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Gopinatth V; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Randle JCR; Random Walk Ventures, LLC, 108 Lincoln Street Unit 6B, Boston, Massachusetts 02111, United States., Chen Z; Department of Pharmacology and Physiology and the Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University School of Medicine, 1402 South Grand Blvd., St. Louis, Missouri 63104, United States., Salvemini D; Department of Pharmacology and Physiology and the Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University School of Medicine, 1402 South Grand Blvd., St. Louis, Missouri 63104, United States., Karcz TP; Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, Durham, North Carolina 27709, United States., Cook DN; Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, Durham, North Carolina 27709, United States., Jacobson KA; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States.
المصدر: Journal of medicinal chemistry [J Med Chem] 2021 Apr 22; Vol. 64 (8), pp. 5099-5122. Date of Electronic Publication: 2021 Mar 31.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
مواضيع طبية MeSH: Piperidines/*chemistry , Purinergic P2 Receptor Antagonists/*chemistry , Receptors, Purinergic P2/*metabolism, Animals ; Binding Sites ; Disease Models, Animal ; Drug Design ; Humans ; Mice ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Neuralgia/drug therapy ; Piperidines/metabolism ; Prodrugs/chemistry ; Prodrugs/metabolism ; Purinergic P2 Receptor Antagonists/metabolism ; Purinergic P2 Receptor Antagonists/therapeutic use ; Receptors, Purinergic P2/chemistry ; Receptors, Purinergic P2/genetics ; Solubility ; Structure-Activity Relationship ; Triazoles/chemistry
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5دورية أكاديمية
المؤلفون: Karcz TP; Immunity, Inflammation and Disease Laboratory., Whitehead GS; Immunity, Inflammation and Disease Laboratory., Nakano K; Immunity, Inflammation and Disease Laboratory., Nakano H; Immunity, Inflammation and Disease Laboratory., Grimm SA; Integrative Bioinformatics., Williams JG; Mass Spectrometry Research and Support Group, Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA., Deterding LJ; Mass Spectrometry Research and Support Group, Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA., Jacobson KA; Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland, USA., Cook DN; Immunity, Inflammation and Disease Laboratory.
المصدر: The Journal of clinical investigation [J Clin Invest] 2021 Apr 01; Vol. 131 (7).
نوع المنشور: Journal Article; Research Support, N.I.H., Intramural
بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
مواضيع طبية MeSH: Asthma/*immunology , Eosinophils/*immunology , Pulmonary Eosinophilia/*immunology , Receptors, Purinergic P2Y/*immunology , Uridine Diphosphate Glucose/*immunology, Allergens/immunology ; Animals ; Asthma/genetics ; Asthma/pathology ; Chemokine CCL24/genetics ; Chemokine CCL24/immunology ; Eosinophils/pathology ; Male ; Mice ; Mice, Knockout ; Pulmonary Eosinophilia/genetics ; Pulmonary Eosinophilia/pathology ; Receptors, Purinergic P2Y/deficiency ; Th2 Cells/immunology ; Th2 Cells/pathology ; Uridine Diphosphate Glucose/genetics
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6دورية أكاديمية
المؤلفون: Jung YH; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Yu J; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Wen Z; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Salmaso V; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Karcz TP; Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, Durham, North Carolina 27709, United States.; Jagiellonian University, Kraków31-007, Poland., Phung NB; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Chen Z; Department of Pharmacology and Physiology and the Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University School of Medicine, 1402 South Grand Boulevard, Saint Louis, Missouri 63104, United States., Duca S; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Bennett JM; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Dudas S; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Salvemini D; Department of Pharmacology and Physiology and the Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University School of Medicine, 1402 South Grand Boulevard, Saint Louis, Missouri 63104, United States., Gao ZG; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Cook DN; Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, Durham, North Carolina 27709, United States., Jacobson KA; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States.
المصدر: Journal of medicinal chemistry [J Med Chem] 2020 Sep 10; Vol. 63 (17), pp. 9563-9589. Date of Electronic Publication: 2020 Aug 06.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
مواضيع طبية MeSH: Drug Design*, Purinergic P2 Receptor Antagonists/*chemistry , Purinergic P2 Receptor Antagonists/*pharmacology , Receptors, Purinergic P2/*metabolism , Triazoles/*chemistry , Triazoles/*pharmacology, Animals ; HEK293 Cells ; Humans ; Inhibitory Concentration 50 ; Mice ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Neuralgia/drug therapy ; Protein Conformation ; Purinergic P2 Receptor Antagonists/metabolism ; Purinergic P2 Receptor Antagonists/therapeutic use ; Receptors, Purinergic P2/chemistry ; Solubility ; Structure-Activity Relationship ; Triazoles/metabolism ; Triazoles/therapeutic use
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7دورية أكاديمية
المؤلفون: Whitehead GS; Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA., Kang HS; Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA., Thomas SY; Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA., Medvedev A; Attagene Inc., Morrisville, North Carolina, USA., Karcz TP; Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA., Izumi G; Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA., Nakano K; Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA., Makarov SS; Attagene Inc., Morrisville, North Carolina, USA., Nakano H; Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA., Jetten AM; Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA., Cook DN; Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA.
المصدر: JCI insight [JCI Insight] 2019 Jun 11; Vol. 5. Date of Electronic Publication: 2019 Jun 11.
نوع المنشور: Journal Article; Research Support, N.I.H., Intramural
بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE
مواضيع طبية MeSH: Asthma/*drug therapy , Hypersensitivity/*drug therapy , Nuclear Receptor Subfamily 1, Group F, Member 3/*therapeutic use , Respiratory Hypersensitivity/*drug therapy, Animals ; Disease Models, Animal ; Dust ; Hypersensitivity/immunology ; Inflammation ; Interleukin-17 ; Lung/pathology ; Mice ; Mice, Inbred C57BL ; Nuclear Receptor Subfamily 1, Group F, Member 3/immunology ; Pneumonia ; Th17 Cells/immunology