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المؤلفون: Karen L. Valentino, Ronald W. Busuttil, Douglas G. Farmer, Marian Kaldas, Charles Lassman, Niel C. Hoglen, Jerzy W. Kupiec-Weglinski, Masamichi Katori, Xiu-Da Shen, Dean M. Anselmo
المصدر: Liver Transplantation. 13:361-366
مصطلحات موضوعية: Male, medicine.medical_specialty, Necrosis, medicine.medical_treatment, Organ Preservation Solutions, Cold storage, Apoptosis, Liver transplantation, Rats, Sprague-Dawley, Internal medicine, medicine, Animals, Viaspan, Enzyme Inhibitors, Pentanoic Acids, Liver injury, Transplantation, TUNEL assay, Hepatology, business.industry, Temperature, Organ Preservation, medicine.disease, Caspase Inhibitors, Rats, Treatment Outcome, medicine.anatomical_structure, Endocrinology, Reperfusion Injury, Hepatocyte, Models, Animal, Immunology, Surgery, medicine.symptom, business, Reperfusion injury
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المؤلفون: Kevin J. Tomaselli, Julia Herrmann, Robert O. Sayers, Joe C. Wu, Lalitha Kodandapani, Kathy G. Jahangiri, Craig D. Fisher, David T. Winn, Edward D. Robinson, Steven P. Meduna, Robert J. Ternansky, Pauline Yeo, Karen L. Valentino, Jose-Luis Diaz, Vincent J. Kalish, Steven D. Linton, Kristen Sebring, Robert A. Armstrong, Joseph F. Krebs, Niel C. Hoglen, Alfred P. Spada, Brad P. Hirakawa, Ning Chen, Brett R. Ullman, Brett Weylan Ching, Cheng-zhi Zhang, Xu Bai, Xin Gu, Kip Nalley, Long-Shiuh Chen, Patricia L. Gladstone, Jeff McQuiston, Teresa Aja, Todd Groessl, Donald S. Karanewsky, Suzanne Weeks, Lawrence C. Fritz, Patricia C. Contreras
المصدر: Journal of Medicinal Chemistry. 48:6779-6782
مصطلحات موضوعية: Adult, Biological Availability, Phases of clinical research, Apoptosis, Pharmacology, Jurkat Cells, Mice, Structure-Activity Relationship, Liver disease, Pharmacokinetics, In vivo, Drug Discovery, medicine, Animals, Humans, Aspartate Aminotransferases, Pentanoic Acids, Caspase, Liver injury, Cholestasis, Clinical Trials, Phase I as Topic, biology, Caspase 3, Chemistry, Liver Diseases, Alanine Transaminase, Hepatitis C, Chronic, medicine.disease, Caspase Inhibitors, In vitro, Rats, Liver, Biochemistry, Enzyme inhibitor, Hepatocytes, biology.protein, Molecular Medicine, Half-Life
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المؤلفون: Brett E. Jones, Anu Srinivasan, Mark J. Czaja, Zehra Pradhan, Karen L. Valentino, Hailing Liu, Richard J. Stockert, Chau R. Lo
المصدر: Journal of Biological Chemistry. 275:40155-40162
مصطلحات موضوعية: Programmed cell death, Necrosis, Apoptosis, Biology, Biochemistry, Cell Line, Proto-Oncogene Proteins c-myc, medicine, Animals, Cytotoxic T cell, Molecular Biology, Death domain, NF-kappa B, Cell Biology, Oligonucleotides, Antisense, Molecular biology, Rats, Enzyme Activation, medicine.anatomical_structure, Cell culture, Caspases, Hepatocyte, Hepatocytes, Tumor necrosis factor alpha, medicine.symptom
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afee02051aa10cea934d4389a34cdb62
https://doi.org/10.1074/jbc.m001565200 -
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المؤلفون: Anu Srinivasan, Karen L. Valentino, Hailing Liu, Brett E. Jones, Lydia Garcia, Chau R. Lo, Zehra Pradhan, Mark J. Czaja
المصدر: American Journal of Physiology-Gastrointestinal and Liver Physiology. 278:G693-G699
مصطلحات موضوعية: Programmed cell death, Vitamin K, Physiology, Apoptosis, Cell Line, chemistry.chemical_compound, Superoxides, Physiology (medical), medicine, Animals, Hydrogen peroxide, Transcription factor, Caspase, Caspase 7, Liver injury, Caspase 8, Cell Death, Hepatology, biology, Caspase 3, Tumor Necrosis Factor-alpha, Superoxide, Caspase 2, NF-kappa B, Gastroenterology, Hydrogen Peroxide, medicine.disease, Caspase 9, Rats, Cell biology, medicine.anatomical_structure, Liver, Biochemistry, chemistry, Caspases, Hepatocyte, biology.protein, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f1e5eb5919e7eea23f7c74c9838781
https://doi.org/10.1152/ajpgi.2000.278.5.g693 -
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المؤلفون: Karen L. Valentino, Mark J. Czaja, Hailing Liu, Brett E. Jones, Chau R. Lo, Anu Srinivasan, Konrad Streetz
المصدر: Journal of Biological Chemistry. 275:705-712
مصطلحات موضوعية: Programmed cell death, Fas-Associated Death Domain Protein, Apoptosis, Cytochrome c Group, Biochemistry, Cell Line, medicine, Animals, FADD, Cytotoxicity, Molecular Biology, Caspase, Adaptor Proteins, Signal Transducing, Death domain, Ploidies, biology, Tumor Necrosis Factor-alpha, NF-kappa B, Cell Biology, Caspase Inhibitors, Molecular biology, Rats, Enzyme Activation, medicine.anatomical_structure, Liver, Caspases, Hepatocyte, Dactinomycin, biology.protein, I-kappa B Proteins, Tumor necrosis factor alpha, Poly(ADP-ribose) Polymerases, Carrier Proteins, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8860f9aae112bab3e81a44947c906cc
https://doi.org/10.1074/jbc.275.1.705 -
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المؤلفون: Mark J. Czaja, Karen L. Valentino, Anu Srinivasan, Chau R. Lo, Brett E. Jones
المصدر: Hepatology. 30:215-222
مصطلحات موضوعية: Male, Programmed cell death, Ceramide, Indoles, Poly ADP ribose polymerase, Apoptosis, Cysteine Proteinase Inhibitors, Cell Line, Rats, Sprague-Dawley, chemistry.chemical_compound, Sphingosine, Animals, Enzyme Inhibitors, Caspase, Nucleic Acid Synthesis Inhibitors, Ploidies, Hepatology, biology, Caspase-Independent Apoptosis, NF-kappa B, Lipid signaling, RALA, Rats, Cell biology, Liver, Biochemistry, chemistry, Caspases, Dactinomycin, biology.protein, Poly(ADP-ribose) Polymerases, Oligopeptides
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المؤلفون: Anu Srinivasan, Gregory J. Gores, Lawrence C. Fritz, Pierre A. Clavien, Markus Selzner, Karen L. Valentino, Shiho Natori
المصدر: Transplantation. 68:89-96
مصطلحات موضوعية: Liver injury, Transplantation, Pathology, medicine.medical_specialty, TUNEL assay, biology, Caspase 3, medicine.disease, Andrology, Endothelial stem cell, medicine, biology.protein, Viaspan, Liver preservation, Caspase
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d1808645941e8fcfd359ac3d90cd9cae
https://doi.org/10.1097/00007890-199907150-00018 -
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المصدر: Drug Information Journal. 31:857-863
مصطلحات موضوعية: business.industry, Public Health, Environmental and Occupational Health, Pharmacology (nursing), Pharmacy, Phase (combat), Outsourcing, Clinical trial, Biopharmaceutical, Risk analysis (engineering), Drug Guides, Return on investment, Pharmacology (medical), Operations management, Business, Preclinical toxicology, Pharmaceutical industry
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2d53ebe5e3272ce640163b7a22037458
https://doi.org/10.1177/009286159703100326 -
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المؤلفون: S. Scott Bowersox, Zofia Zukowska-Grojec, Tejinder Singh, Laszlo Nadasdi, Karen L. Valentino, Brian B. Hoffman
المصدر: Journal of Cardiovascular Pharmacology. 20:756-764
مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, Arginine, Calcium channel, Stimulation, Biology, Omega-Conotoxins, Blockade, Norepinephrine (medication), chemistry.chemical_compound, Endocrinology, chemistry, Internal medicine, Heart rate, medicine, Cardiology and Cardiovascular Medicine, Histamine, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9422f609c5afb304a589bfb8b255b6ea
https://doi.org/10.1097/00005344-199211000-00011 -
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المؤلفون: Karen L. Valentino, Marcelo J. Villar, Monique Huchet, Tomas Hökfelt, Jean-Pierre Changeux, Michèle Roa
المصدر: Brain Research. 541:149-153
مصطلحات موضوعية: Embryo, Nonmammalian, Central nervous system, Fluorescent Antibody Technique, Chick Embryo, Biology, Embryonic and Fetal Development, Neurotrophic factors, Tachykinins, medicine, Animals, Molecular Biology, Neuropeptide K, Motor Neurons, General Neuroscience, Neuropeptides, Embryogenesis, Embryo, Anatomy, Motor neuron, Embryo, Mammalian, Spinal cord, Embryonic stem cell, medicine.anatomical_structure, Spinal Cord, Neurology (clinical), Developmental Biology