المؤلفون: Karima Habbout, Junichi Omura, Charifa Awada, Alice Bourgeois, Yann Grobs, Vinod Krishna, Sandra Breuils-Bonnet, Eve Tremblay, Ghada Mkannez, Sandra Martineau, Valérie Nadeau, Florence Roux-Dalvai, Mark Orcholski, Jey Jeyaseelan, David Gutstein, François Potus, Steeve Provencher, Sébastien Bonnet, Roxane Paulin, Olivier Boucherat

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 6, p 2957 (2021)

مصطلحات موضوعية: vascular remodeling, epigenetics, metabolism, right ventricle, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1422-0067/22/6/2957; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067

URL الوصول: https://doaj.org/article/cf1ef3e146fd42f8b2577f234c9e0913

المؤلفون: Sandra Breuils-Bonnet, Allan Lawrie, Stephen L. Archer, Eve Tremblay, Tsukasa Shimauchi, François Potus, David G. Kiely, Wen-Hui Wu, Jianhui Lin, Olivier Boucherat, Valérie Nadeau, Sébastien Bonnet, Kassandra Gagnon, Sandra Martineau, Karima Habbout, Hamza Zafar, Roxane Paulin, Steeve Provencher, Junichi Omura, Jean Perron, Florence Mazoyer

المصدر: Circulation. 142:1464-1484

مصطلحات موضوعية: medicine.medical_specialty, Ventricular Dysfunction, Right, Hemodynamics, Vascular Remodeling, 030204 cardiovascular system & hematology, Muscle hypertrophy, 03 medical and health sciences, 0302 clinical medicine, Fibrosis, Physiology (medical), Internal medicine, Natriuretic Peptide, Brain, Animals, Humans, Medicine, In patient, 030304 developmental biology, Heart Failure, Pulmonary Arterial Hypertension, 0303 health sciences, business.industry, medicine.disease, Peptide Fragments, Long non-coding RNA, Rats, Heart failure, Cardiology, Biomarker (medicine), Right ventricular failure, RNA, Long Noncoding, Cardiology and Cardiovascular Medicine, business, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e40c0755eff6d2f6718ab7a141e5da3
https://doi.org/10.1161/circulationaha.120.047626

المؤلفون: Sébastien Bonnet, Karima Habbout, Alice Bourgeois, Junichi Omura, Olivier Boucherat

المصدر: The International Journal of Biochemistry & Cell Biology. 104:9-13

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Hypertension, Pulmonary, 030204 cardiovascular system & hematology, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Smooth muscle, medicine.artery, Internal medicine, medicine, Humans, Molecular Targeted Therapy, Pathological, business.industry, Cell Biology, Pathophysiology, Review article, 030104 developmental biology, medicine.anatomical_structure, Underlying disease, Pulmonary artery, Cardiology, Vascular resistance, medicine.symptom, business, Vasoconstriction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba6eeff4ffbf11364b5526830f1ac9d
https://doi.org/10.1016/j.biocel.2018.08.015

المؤلفون: Olivier Boucherat, Charifa Awada, Sébastien Bonnet, Roxane Paulin, Sandra Breuils-Bonnet, Karima Habbout, Steeve Provencher, Valérie Nadeau

المصدر: Circulation. 142

مصطلحات موضوعية: medicine.medical_specialty, business.industry, medicine.disease, Pulmonary hypertension, Premature death, Smooth muscle, Physiology (medical), medicine.artery, Internal medicine, Histone methyltransferase, Heart failure, Pulmonary artery, medicine, Cardiology, Epigenetics, Cardiology and Cardiovascular Medicine, business, Hypertension experimental

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fee418086734b131ce7aeee08cee68fb
https://doi.org/10.1161/circ.142.suppl_3.15544

المؤلفون: Sarah-Eve Lemay, Roxane Paulin, Alice Bourgeois, Eve Tremblay, Renée Paradis, Geraldine Vitry, Karima Habbout, Marie-Claude Lampron, Olivier Boucherat, Sandra Breuils-Bonnet, Florence Roux-Dalvai, Yann Grobs, Charifa Awada, Tsukasa Shimauchi, Mark Orcholski, Valérie Nadeau, Steeve Provencher, François Potus, Sébastien Bonnet

المصدر: American Journal of Respiratory and Critical Care Medicine

مصطلحات موضوعية: Male, Cell, Apoptosis, Pharmacology, Critical Care and Intensive Care Medicine, medicine.disease_cause, Muscle, Smooth, Vascular, Tandem Mass Spectrometry, Pyrophosphatases, Pulmonary Arterial Hypertension, Middle Aged, Up-Regulation, medicine.anatomical_structure, 8-Hydroxy-2'-Deoxyguanosine, Female, Comet Assay, Oxidation-Reduction, Pulmonary and Respiratory Medicine, Adult, Programmed cell death, DNA damage, Blotting, Western, Myocytes, Smooth Muscle, In Vitro Techniques, Pulmonary Artery, Vascular Remodeling, medicine, Animals, Humans, RNA, Messenger, Aged, Cell Proliferation, business.industry, Forkhead Box Protein M1, Editorials, DNA, medicine.disease, Pulmonary hypertension, Phosphoric Monoester Hydrolases, Rats, Comet assay, Disease Models, Animal, Oxidative Stress, DNA Repair Enzymes, Terminal deoxynucleotidyl transferase, Case-Control Studies, business, Oxidative stress, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30618c1c0a8f8c41797ea0089406445b
https://pubmed.ncbi.nlm.nih.gov/33095993

المؤلفون: Yann Grobs, Olivier Boucherat, Sandra Breuils-Bonnet, Steeve Provencher, François Potus, Charlotte Romanet, Charifa Awada, Sandra Martineau, Wen-Hui Wu, Eve Tremblay, Karima Habbout, Sébastien Bonnet, Roxane Paulin

المصدر: The European respiratory journal. 57(5)

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Pulmonary Arterial Hypertension, business.industry, Hypertension, Pulmonary, Conflict of interest, Disease, Pulmonary Artery, Bioinformatics, medicine.disease, Pulmonary hypertension, Vascular remodelling in the embryo, Dasatinib, Disease Models, Animal, Smooth muscle, Crizotinib, Nothing, Models, Animal, (R)-crizotinib, Medicine, Animals, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28cc1914696b1b0309b67dba800cf4a4
https://pubmed.ncbi.nlm.nih.gov/33446610

المؤلفون: Olivier Boucherat, S. Provencher, Roxanne Paulin, Valérie Nadeau, Sandra Breuils Bonnet, Charifa Awada, Karima Habbout, S. Breuils Bonnet

المصدر: D25. O BRAVE NEW WORLD! OMICS, SYSTEM BIOLOGY, AND NEW MOLECULAR MECHANISMS OF PULMONARY HYPERTENSION.

مصطلحات موضوعية: Functional role, medicine.medical_specialty, business.industry, Internal medicine, medicine, Cardiology, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::50660b6f413b145a58783ed05000759c
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6361

المؤلفون: François Potus, Sandra Martineau, Junichi Omura, Sandra Breuils-Bonnet, S. Provencher, Valérie Nadeau, Karima Habbout, Eve Tremblay, Hamza Zafar, Sandra Breuils Bonnet, Allan Lawrie, Jianhui Lin, Olivier Boucherat, Stephen L. Archer, Tsukasa Shimauchi, Roxane Paulin, David G. Kiely

المصدر: C105. WITH ALL MY HEART: SEX, ESTROGEN, AND RIGHT VENTRICLE IN PULMONARY VASCULAR DISEASE AND BEYOND.

مصطلحات موضوعية: medicine.medical_specialty, business.industry, Internal medicine, medicine, Cardiology, Right ventricular failure, Biomarker (medicine), Identification (biology), business, Long non-coding RNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8c7eb4d0d6d7f62ab6de0da6f5291996
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6076

المؤلفون: Sandra Breuils Bonnet, Karima Habbout, François Potus, Roxane Paulin, Stephen L. Archer, Sandra Martineau, Sandra Breuils-Bonnet, Jianhui Lin, Olivier Boucherat, Eve Tremblay, Allan Lawrie, Valérie Nadeau, David G. Kiely, Junichi Omura, S. Provencher, Tsukasa Shimauchi, Hamza Zafar

المصدر: A93. TRANSLATIONAL RESEARCH; EARLY CLINICAL FINDINGS AND OMICS ADVENTURE IN PULMONARY HYPERTENSION: FROM BIOMARKERS TO NEW THERAPEUTIC TARGETS.

مصطلحات موضوعية: medicine.medical_specialty, business.industry, Internal medicine, Cardiology, Medicine, Right ventricular failure, business, Long non-coding RNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c410092f010b56a8adc6b8b0ecd221e3
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2496

المؤلفون: Karima Habbout, Ravi Jahagirdar, Guido P. L. Bossers, Sandra Martineau, Roxane Paulin, Beatrijs Bartelds, Robert Szulcek, Marie-Claude Lampron, Marie-José Goumans, Alice Bourgeois, Rolf M. F. Berger, Diederik E. van der Feen, Eve Tremblay, Ingrid Schalij, Ewelina Kulikowski, Olivier Boucherat, Steeve Provencher, Harm Jan Bogaard, Kondababu Kurakula, Sébastien Bonnet

المساهمون: Physiology, ACS - Pulmonary hypertension & thrombosis, Pulmonary medicine, Pediatrics, Cardiovascular Centre (CVC)

المصدر: American Journal of Respiratory and Critical Care Medicine, 200(7), 910-920. American Thoracic Society
American Journal of Respiratory and Critical Care Medicine, 200(7), 910-920. AMER THORACIC SOC
Van der Feen, D E, Kurakula, K, Tremblay, E, Boucherat, O, Bossers, G PL, Szulcek, R, Bourgeois, A, Lampron, M-C, Habbout, K, Martineau, S, Paulin, R, Kulikowski, E, Jahagirdar, R, Schalij, I, Bogaard, H J, Bartelds, B, Provencher, S, Berger, R M F, Bonnet, S & Goumans, M-J 2019, ' Multicenter preclinical validation of BET inhibition for the treatment of pulmonary arterial hypertension ', American Journal of Respiratory and Critical Care Medicine, vol. 200, no. 7, pp. 910-920 . https://doi.org/10.1164/rccm.201812-2275OC, https://doi.org/10.1164/rccm.201812-2275OC

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, BET inhibition, DNA Repair, vascular remodeling, Myocytes, Smooth Muscle, Inflammation, Apoptosis, Cell Cycle Proteins, Pharmacology, Protein Serine-Threonine Kinases, Pulmonary Artery, Critical Care and Intensive Care Medicine, Muscle, Smooth, Vascular, Pulmonary artery banding, Proinflammatory cytokine, BET inhibitor, BRD4 (bromodomain-containing protein 4), Downregulation and upregulation, INFLAMMATION, In vivo, Proto-Oncogene Proteins, pulmonary arterial hypertension, medicine, Animals, Humans, Receptor, Cell Proliferation, Quinazolinones, Pressure overload, RECEPTOR, business.industry, Forkhead Box Protein M1, FOXM1, Endothelial Cells, CANCER, Rats, Disease Models, Animal, Gene Expression Regulation, Microvessels, medicine.symptom, business, Transcription Factors, right ventricle pressure load

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1080444cf954254efa11ac9596014acf
https://research.vumc.nl/en/publications/05a0fffc-21eb-4c2c-8b59-541f22c7d740