المؤلفون: Orlando Borges Filho, Angela Ribas, Claudia Giglio De Oliveira Gonçalves, Adriana Bender Moreira Lacerda, Renato Riesemberg, Karlin Klagenberg

المصدر: International Archives of Otorhinolaryngology, Vol 21, Iss 04, Pp 313-317 (2017)

مصطلحات موضوعية: perception, noise, schools, environmental pollution, Medicine, Otorhinolaryngology, RF1-547

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1809-9777; https://doaj.org/toc/1809-4864

URL الوصول: https://doaj.org/article/3d1a4427a9654eeab05b0c97a3377a3b

المؤلفون: Arabzade A; Department of Chemical and Biomolecular Engineering, Rice University, Houston, Texas.; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas., Zhao Y; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas., Varadharajan S; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas., Chen HC; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas.; Cancer and Cell Biology Program, Baylor College of Medicine, Dan L. Duncan Cancer Center, Houston, Texas., Jessa S; Quantitative Life Sciences, McGill University, Montreal, Quebec, Canada., Rivas B; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas., Stuckert AJ; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas., Solis M; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas.; Cancer and Cell Biology Program, Baylor College of Medicine, Dan L. Duncan Cancer Center, Houston, Texas., Kardian A; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas.; Cancer and Cell Biology Program, Baylor College of Medicine, Dan L. Duncan Cancer Center, Houston, Texas., Tlais D; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas., Golbourn BJ; Department of Neurological Surgery, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Stanton AJ; Department of Neurological Surgery, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Chan YS; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas.; Department of Molecular and Cellular Biology and Center for Precision Environmental Health, Baylor College of Medicine, Houston, Texas.; Department of Bioengineering, Rice University, Houston, Texas.; Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Olson C; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.; Department of Biochemistry and Molecular Biology, Houston, Texas., Karlin KL; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.; Department of Biochemistry and Molecular Biology, Houston, Texas., Kong K; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas., Kupp R; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, England.; Department of Oncology, University of Cambridge, Hutchison/MRC Research Centre, Cambridge Biomedical Campus, Cambridge, England., Hu B; Department of Neurological Surgery, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Injac SG; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas., Ngo M; Department of Chemical and Biomolecular Engineering, Rice University, Houston, Texas., Wang PR; Department of Chemical and Biomolecular Engineering, Rice University, Houston, Texas., De León LA; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas., Sahm F; Hopp-Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany., Kawauchi D; Hopp-Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Biochemistry and Cellular Biology, National Center of Neurology and Psychiatry (NCNP), Tokyo, Japan., Pfister SM; Hopp-Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; Department of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany., Lin CY; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas., Hodges HC; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas.; Department of Molecular and Cellular Biology and Center for Precision Environmental Health, Baylor College of Medicine, Houston, Texas.; Department of Bioengineering, Rice University, Houston, Texas.; Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Singh I; Department of Molecular and Cellular Medicine, College of Medicine, Texas A&M University Health Science Center, Bryan, Texas., Westbrook TF; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.; Department of Biochemistry and Molecular Biology, Houston, Texas., Chintagumpala MM; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas., Blaney SM; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas., Parsons DW; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas., Pajtler KW; Hopp-Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; Department of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany., Agnihotri S; Department of Neurological Surgery, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Gilbertson RJ; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, England.; Department of Oncology, University of Cambridge, Hutchison/MRC Research Centre, Cambridge Biomedical Campus, Cambridge, England., Yi J; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas., Jabado N; Quantitative Life Sciences, McGill University, Montreal, Quebec, Canada.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada., Kleinman CL; Quantitative Life Sciences, McGill University, Montreal, Quebec, Canada.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada.; Lady Davis Research Institute, Jewish General Hospital, Quebec, Canada., Bertrand KC; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas. stephen.mack@stjude.org deneen@bcm.edu stephen.mack@stjude.org.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas., Deneen B; Cancer and Cell Biology Program, Baylor College of Medicine, Dan L. Duncan Cancer Center, Houston, Texas. stephen.mack@stjude.org deneen@bcm.edu stephen.mack@stjude.org.; Program in Developmental Biology, Baylor College of Medicine, Houston, Texas.; Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas.; Department of Neurosurgery, Baylor College of Medicine, Houston, Texas., Mack SC; Department of Pediatrics, Division of Pediatric Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, Texas. stephen.mack@stjude.org deneen@bcm.edu stephen.mack@stjude.org.; Therapeutic Innovation Center at Baylor College of Medicine, Houston, Texas.; Cancer and Cell Biology Program, Baylor College of Medicine, Dan L. Duncan Cancer Center, Houston, Texas.

المصدر: Cancer discovery [Cancer Discov] 2021 Sep; Vol. 11 (9), pp. 2200-2215. Date of Electronic Publication: 2021 Mar 19.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: DNA-Binding Proteins/*genetics , Ependymoma/*genetics , Supratentorial Neoplasms/*genetics , Transcription Factor RelA/*genetics , Transcription Factors/*genetics, Animals ; Disease Models, Animal ; Ependymoma/pathology ; Mice ; Supratentorial Neoplasms/pathology

المؤلفون: Richters A; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; MIT Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Doyle SK; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; MIT Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Freeman DB; Kronos Bio, Inc., Cambridge, MA 02139, USA., Lee C; Kronos Bio, Inc., Cambridge, MA 02139, USA., Leifer BS; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; MIT Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Jagannathan S; Therapeutic Innovation Center, Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Kabinger F; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; MIT Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Koren JV; Therapeutic Innovation Center, Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Struntz NB; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; MIT Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Urgiles J; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Harvard-MIT Health Sciences and Technology, Boston, MA 02115, USA., Stagg RA; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Department of Biology, Boston University, Boston, MA 02215, USA., Curtin BH; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; MIT Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Chatterjee D; Goethe-Universität Frankfurt, 60438 Frankfurt am Main, Germany., Mathea S; Goethe-Universität Frankfurt, 60438 Frankfurt am Main, Germany., Mikochik PJ; Kronos Bio, Inc., Cambridge, MA 02139, USA., Hopkins TD; Kronos Bio, Inc., Cambridge, MA 02139, USA., Gao H; Kronos Bio, Inc., Cambridge, MA 02139, USA., Branch JR; Janssen Research & Development, LLC, Spring House, PA, USA., Xin H; Janssen Research & Development, LLC, Spring House, PA, USA., Westover L; Janssen Research & Development, LLC, Spring House, PA, USA., Bignan GC; Janssen Research & Development, LLC, Spring House, PA, USA., Rupnow BA; Janssen Research & Development, LLC, Spring House, PA, USA., Karlin KL; Therapeutic Innovation Center, Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Olson CM; Therapeutic Innovation Center, Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Westbrook TF; Therapeutic Innovation Center, Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Vacca J; Kronos Bio, Inc., Cambridge, MA 02139, USA., Wilfong CM; Kronos Bio, Inc., Cambridge, MA 02139, USA., Trotter BW; Kronos Bio, Inc., Cambridge, MA 02139, USA., Saffran DC; Kronos Bio, Inc., Cambridge, MA 02139, USA., Bischofberger N; Kronos Bio, Inc., Cambridge, MA 02139, USA., Knapp S; Goethe-Universität Frankfurt, 60438 Frankfurt am Main, Germany., Russo JW; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Hickson I; Janssen Research & Development, LLC, Spring House, PA, USA; Cancer Research UK Newcastle Drug Discovery Unit, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne NE2 4HH, UK., Bischoff JR; Janssen Research & Development, LLC, Spring House, PA, USA., Gottardis MM; Janssen Research & Development, LLC, Spring House, PA, USA., Balk SP; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Lin CY; Kronos Bio, Inc., Cambridge, MA 02139, USA; Therapeutic Innovation Center, Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Pop MS; Kronos Bio, Inc., Cambridge, MA 02139, USA., Koehler AN; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; MIT Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address: koehler@mit.edu.

المصدر: Cell chemical biology [Cell Chem Biol] 2021 Feb 18; Vol. 28 (2), pp. 134-147.e14. Date of Electronic Publication: 2020 Oct 20.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Androgen Receptor Antagonists/*pharmacology , Cyclin-Dependent Kinase 9/*antagonists & inhibitors , Prostatic Neoplasms, Castration-Resistant/*drug therapy , Protein Kinase Inhibitors/*pharmacology , Receptors, Androgen/*genetics , Transcription, Genetic/*drug effects, Androgen Receptor Antagonists/therapeutic use ; Animals ; Cell Line, Tumor ; Cyclin-Dependent Kinase 9/genetics ; Gene Expression Regulation, Neoplastic/drug effects ; Male ; Mice ; Mice, Inbred BALB C ; Models, Molecular ; Prostatic Neoplasms, Castration-Resistant/genetics ; Protein Kinase Inhibitors/therapeutic use

المؤلفون: Bowling EA; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Wang JH; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX 77030, USA., Gong F; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Wu W; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX 77030, USA., Neill NJ; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Kim IS; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA., Tyagi S; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Orellana M; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Kurley SJ; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Dominguez-Vidaña R; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Chung HC; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Hsu TY; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX 77030, USA., Dubrulle J; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Saltzman AB; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Li H; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Meena JK; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Canlas GM; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX 77030, USA., Chamakuri S; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX 77030, USA., Singh S; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA., Simon LM; Therapeutic Innovation Center, Baylor College of Medicine, Houston, TX 77030, USA., Olson CM; Therapeutic Innovation Center, Baylor College of Medicine, Houston, TX 77030, USA., Dobrolecki LE; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA., Lewis MT; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Zhang B; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Golding I; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Rosen JM; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Young DW; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX 77030, USA; Therapeutic Innovation Center, Baylor College of Medicine, Houston, TX 77030, USA., Malovannaya A; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Stossi F; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Miles G; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Ellis MJ; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Yu L; H3Biomedicine, Cambridge, MA 02139, USA., Buonamici S; H3Biomedicine, Cambridge, MA 02139, USA., Lin CY; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Therapeutic Innovation Center, Baylor College of Medicine, Houston, TX 77030, USA; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Karlin KL; Therapeutic Innovation Center, Baylor College of Medicine, Houston, TX 77030, USA., Zhang XH; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Westbrook TF; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Therapeutic Innovation Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: thomasw@bcm.edu.

المصدر: Cell [Cell] 2021 Jan 21; Vol. 184 (2), pp. 384-403.e21. Date of Electronic Publication: 2021 Jan 14.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: Antiviral Agents/*pharmacology , Immunity/*drug effects , Spliceosomes/*metabolism , Triple Negative Breast Neoplasms/*immunology , Triple Negative Breast Neoplasms/*pathology, Adaptive Immunity/drug effects ; Animals ; Apoptosis/drug effects ; Cell Line, Tumor ; Cytoplasm/drug effects ; Cytoplasm/metabolism ; Female ; Gene Amplification/drug effects ; Humans ; Introns/genetics ; Mice ; Molecular Targeted Therapy ; Proto-Oncogene Proteins c-myc/metabolism ; RNA Splicing/drug effects ; RNA Splicing/genetics ; RNA, Double-Stranded/metabolism ; Signal Transduction/drug effects ; Spliceosomes/drug effects ; Triple Negative Breast Neoplasms/genetics

المؤلفون: Mowery CT; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Reyes JM; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Cabal-Hierro L; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Higby KJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Karlin KL; Verna and Marrs McLean Department of Biochemistry and Molecular Biology and Therapeutic Innovation Center, Baylor College of Medicine, Houston, TX, USA., Wang JH; Interdepartmental Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, TX, USA., Kimmerling RJ; Koch Institute for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Cejas P; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA, USA., Lim K; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA, USA., Li H; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Furusawa T; Laboratory of Metabolism, National Cancer Institute, Bethesda, MD, USA., Long HW; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA, USA., Pellman D; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA., Chapuy B; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Department of Hematology and Oncology, University Medical Center Göttingen, Göttingen, Germany., Bustin M; Laboratory of Metabolism, National Cancer Institute, Bethesda, MD, USA., Manalis SR; Koch Institute for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Westbrook TF; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA; Verna and Marrs McLean Department of Biochemistry and Molecular Biology and Therapeutic Innovation Center, Baylor College of Medicine, Houston, TX, USA; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Lin CY; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA; Verna and Marrs McLean Department of Biochemistry and Molecular Biology and Therapeutic Innovation Center, Baylor College of Medicine, Houston, TX, USA., Lane AA; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Broad Institute of Harvard and MIT, Cambridge, MA, USA. Electronic address: andrew_lane@dfci.harvard.edu.

المصدر: Cell reports [Cell Rep] 2018 Nov 13; Vol. 25 (7), pp. 1898-1911.e5.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Transcription, Genetic*, Down Syndrome/*genetics , HMGN1 Protein/*genetics , Trisomy/*genetics, Acetylation ; Animals ; B-Lymphocytes/metabolism ; Cell Line ; Genome ; HMGN1 Protein/metabolism ; Histones/metabolism ; Humans ; Lysine/metabolism ; Mice, Inbred C57BL ; Models, Genetic ; Nucleosomes/metabolism ; Phenotype ; RNA/genetics ; Transcriptome/genetics ; Up-Regulation/genetics

SCR Disease Name: Down Syndrome Critical Region

المؤلفون: Zeid R; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Lawlor MA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Poon E; Division of Clinical Studies, The Institute of Cancer Research, London, UK.; Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK., Reyes JM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Fulciniti M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; LeBow Institute for Myeloma Therapeutics and Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Boston, MA, USA., Lopez MA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; LeBow Institute for Myeloma Therapeutics and Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Boston, MA, USA., Scott TG; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Nabet B; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Erb MA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Winter GE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Jacobson Z; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Polaski DR; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Karlin KL; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Hirsch RA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Munshi NP; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; LeBow Institute for Myeloma Therapeutics and Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Boston, MA, USA., Westbrook TF; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Chesler L; Division of Clinical Studies, The Institute of Cancer Research, London, UK.; Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK., Lin CY; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. charles.y.lin@bcm.edu.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA. charles.y.lin@bcm.edu., Bradner JE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. james.bradner@novartis.com.; Department of Medicine, Harvard Medical School, Boston, MA, USA. james.bradner@novartis.com.; Novartis Institute for Biomedical Research, Cambridge, MA, USA. james.bradner@novartis.com.

المصدر: Nature genetics [Nat Genet] 2018 Apr; Vol. 50 (4), pp. 515-523. Date of Electronic Publication: 2018 Jan 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

مواضيع طبية MeSH: N-Myc Proto-Oncogene Protein/*genetics , Neuroblastoma/*genetics, Binding Sites/genetics ; Cell Line, Tumor ; Chromatin/genetics ; Chromatin/metabolism ; Enhancer Elements, Genetic ; Gene Amplification ; Genes, myc ; Humans ; Kinetics ; N-Myc Proto-Oncogene Protein/metabolism ; Neuroblastoma/metabolism ; Nuclear Proteins/metabolism ; Oncogenes ; Promoter Regions, Genetic ; Twist-Related Protein 1/metabolism

المؤلفون: Mahamdallie SS, Hanks S, Karlin KL, Zachariou A, Perdeaux ER, Ruark E, Shaw CA, Renwick A, Ramsay E, Yost S, Elliott A, Birch J, Capra M, Gray J, Hale J, Kingston J, Levitt G, McLean T, Sheridan E, Renwick A, Seal S, Stiller C, Sebire N, Westbrook TF, Rahman N

المصدر: Nature genetics [Nat Genet] 2016 Apr; Vol. 48 (4), pp. 473.

نوع المنشور: Published Erratum

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: PubMed not MEDLINE

المؤلفون: Mahamdallie SS; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK., Hanks S; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK., Karlin KL; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA., Zachariou A; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK., Perdeaux ER; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK., Ruark E; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK., Shaw CA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA., Renwick A; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA., Ramsay E; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK., Yost S; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK., Elliott A; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK., Birch J; Paediatric and Familial Cancer Research Group, University of Manchester, Manchester, UK., Capra M; Haematology Oncology-National Paediatric Centre, Our Lady's Children's Hospital, Dublin, Ireland., Gray J; Cancer Sciences Unit, University of Southampton, Southampton, UK., Hale J; Department of Paediatric and Adolescent Haematology and Oncology, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK., Kingston J; Department of Haematology and Oncology, Great Ormond Street Hospital, London, UK., Levitt G; Department of Haematology and Oncology, Great Ormond Street Hospital, London, UK., McLean T; Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA., Sheridan E; Yorkshire Clinical Genetics Service, Chapel Allerton Hospital, Leeds, UK., Renwick A; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK., Seal S; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK., Stiller C; Public Health England, Oxford, UK., Sebire N; Department of Histopathology and Paediatric Laboratory Medicine, Great Ormond Street Hospital, London, UK., Westbrook TF; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA., Rahman N; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.; Cancer Genetics Unit, Royal Marsden Hospital National Health Service (NHS) Foundation Trust, London, UK.

المصدر: Nature genetics [Nat Genet] 2015 Dec; Vol. 47 (12), pp. 1471-4. Date of Electronic Publication: 2015 Nov 09.

نوع المنشور: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation* , Genetic Predisposition to Disease*, Genetic Markers/*genetics , Kidney Neoplasms/*genetics , Mutation/*genetics , Repressor Proteins/*genetics , Wilms Tumor/*genetics, Case-Control Studies ; Humans

المؤلفون: Hsu TY; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.; Interdepartmental Program in Molecular and Biomedical Sciences, Baylor College of Medicine, Houston, Texas 77030, USA.; Medical Scientist Training Program, Baylor College of Medicine, Houston, Texas 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA., Simon LM; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA., Neill NJ; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA., Marcotte R; Princess Margaret Cancer Centre, University Health Network, Toronto M5G 2C4, Canada., Sayad A; Princess Margaret Cancer Centre, University Health Network, Toronto M5G 2C4, Canada., Bland CS; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA., Echeverria GV; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas 77030, USA.; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas 77030, USA.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA., Sun T; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA., Kurley SJ; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA., Tyagi S; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA., Karlin KL; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA., Dominguez-Vidaña R; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.; Interdepartmental Program in Molecular and Biomedical Sciences, Baylor College of Medicine, Houston, Texas 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA., Hartman JD; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA., Renwick A; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA., Scorsone K; Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA., Bernardi RJ; Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA., Skinner SO; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.; Department of Physics, University of Illinois, Urbana, Illinois 61801, USA., Jain A; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA., Orellana M; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA., Lagisetti C; Center for Chemical Biology, Bioscience Division, SRI International, Menlo Park, California 94025, USA., Golding I; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.; Department of Physics, University of Illinois, Urbana, Illinois 61801, USA., Jung SY; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA., Neilson JR; Interdepartmental Program in Molecular and Biomedical Sciences, Baylor College of Medicine, Houston, Texas 77030, USA.; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas 77030, USA., Zhang XH; The Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas 77030, USA., Cooper TA; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas 77030, USA.; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas 77030, USA.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA., Webb TR; Center for Chemical Biology, Bioscience Division, SRI International, Menlo Park, California 94025, USA., Neel BG; Princess Margaret Cancer Centre, University Health Network, Toronto M5G 2C4, Canada.; Department of Medical Biophysics, University of Toronto, Toronto M5S 2J7, Canada., Shaw CA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA., Westbrook TF; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.; Interdepartmental Program in Molecular and Biomedical Sciences, Baylor College of Medicine, Houston, Texas 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.

المصدر: Nature [Nature] 2015 Sep 17; Vol. 525 (7569), pp. 384-8. Date of Electronic Publication: 2015 Sep 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms/*drug therapy , Breast Neoplasms/*genetics , Genes, myc/*genetics , Spliceosomes/*drug effects , Spliceosomes/*metabolism, Animals ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Transformation, Neoplastic/drug effects ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; HeLa Cells ; Humans ; Introns/genetics ; Mice ; Mice, Nude ; Neoplasm Metastasis/drug therapy ; Nuclear Proteins/metabolism ; Phosphoproteins/metabolism ; Proto-Oncogene Proteins c-myc/genetics ; Proto-Oncogene Proteins c-myc/metabolism ; RNA Precursors/biosynthesis ; RNA Precursors/genetics ; RNA Splicing/drug effects ; RNA Splicing Factors ; RNA, Messenger/biosynthesis ; RNA, Messenger/genetics ; Ribonucleoprotein, U2 Small Nuclear/metabolism ; Ribonucleoproteins/metabolism ; Splicing Factor U2AF ; Xenograft Model Antitumor Assays

المؤلفون: Karlin KL; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Integrative Molecular and Biomedical Sciences Program, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Mondal G; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA., Hartman JK; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Tyagi S; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Kurley SJ; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Bland CS; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Hsu TY; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Integrative Molecular and Biomedical Sciences Program, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Renwick A; Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Fang JE; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Migliaccio I; The Lester and Sue Smith Breast Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Callaway C; Department of Molecular and Cell Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Department of Pathology and Immunology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Nair A; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Dominguez-Vidana R; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Integrative Molecular and Biomedical Sciences Program, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Nguyen DX; Department of Pathology, Yale University School of Medicine, Yale Cancer Center, New Haven, CT 06510, USA., Osborne CK; The Lester and Sue Smith Breast Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Schiff R; The Lester and Sue Smith Breast Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Yu-Lee LY; Department of Molecular and Cell Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Jung SY; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Edwards DP; Department of Molecular and Cell Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Department of Pathology and Immunology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Hilsenbeck SG; Dan L. Duncan Cancer Center Division of Biostatistics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Rosen JM; Department of Molecular and Cell Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Zhang XH; Department of Molecular and Cell Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; The Lester and Sue Smith Breast Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Shaw CA; Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA., Westbrook TF; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Integrative Molecular and Biomedical Sciences Program, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. Electronic address: thomasw@bcm.edu.

المصدر: Cell reports [Cell Rep] 2014 Nov 20; Vol. 9 (4), pp. 1318-32. Date of Electronic Publication: 2014 Nov 06.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction*, Repressor Proteins/*metabolism , Triple Negative Breast Neoplasms/*metabolism , Triple Negative Breast Neoplasms/*pathology, Animals ; Carcinogenesis/pathology ; Cell Cycle Proteins/metabolism ; Cell Line, Tumor ; Cell Transformation, Neoplastic/pathology ; Female ; Gene Amplification ; Humans ; Mice ; Neoplasm Metastasis ; Phosphorylation ; Protein Serine-Threonine Kinases/metabolism ; Proteolysis ; Proto-Oncogene Proteins/metabolism ; Transcription, Genetic ; Treatment Outcome ; Triple Negative Breast Neoplasms/genetics ; Polo-Like Kinase 1