المؤلفون: Kimberly Sauls, Katelynn Toomer, Katherine Williams, Amanda J. Johnson, Roger R. Markwald, Zoltan Hajdu, Russell A. Norris

المصدر: Journal of Cardiovascular Development and Disease, Vol 2, Iss 3, Pp 200-213 (2015)

مصطلحات موضوعية: Filamin-A, myxomatous valve disease, hematopoietic cells, macrophage, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: http://www.mdpi.com/2308-3425/2/3/200; https://doaj.org/toc/2308-3425

URL الوصول: https://doaj.org/article/6f0cef17ec8440c9bfe5c058f1a7d8be

المؤلفون: Thomas R. Christiani, author¹, Katelynn Toomer, author², Joseph Sheehan, author², Angelika Nitzl, author², Amanda Branda, author², Elizabeth England, author², Pamela Graney, author³, Cristina Iftode, author², Andrea J. Vernengo, author¹

المصدر: Journal of Visualized Experiments. (116)

الإتاحة: http://www.jove.com/video/53704

المؤلفون: Rebecca Stairley, Yujing Dang, Reece Moore, Kelsey Moore, Katelynn Toomer, Patrick D. Gerard, Dongjun Chung, Mahyar Heydarpour, Diana Fulmer, Xiaofeng Zuo, Lilong Guo, Russell A. Norris, Janiece Glover, Simon C. Body, Rupak Mukherjee, Glenn P. Lobo, Joshua H. Lipschutz, Yanhui Su, Ben Fogelgren

المصدر: Circulation

مصطلحات موضوعية: Heart Defects, Congenital, Aortic valve, medicine.medical_specialty, Genotype, Population, Heart Valve Diseases, Vesicular Transport Proteins, Exocyst, Disease, 030204 cardiovascular system & hematology, Polymorphism, Single Nucleotide, Article, Mice, 03 medical and health sciences, 0302 clinical medicine, Bicuspid aortic valve, Bicuspid Aortic Valve Disease, Gene Frequency, Physiology (medical), Internal medicine, Animals, Humans, Medicine, Cilia, education, Zebrafish, 030304 developmental biology, Mice, Knockout, 0303 health sciences, education.field_of_study, business.industry, Cilium, Aortic Valve Stenosis, Zebrafish Proteins, medicine.disease, Stenosis, medicine.anatomical_structure, Aortic Valve, Case-Control Studies, Aortic valve stenosis, cardiovascular system, Cardiology, Cardiology and Cardiovascular Medicine, business, Genome-Wide Association Study

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d7fd3ea6ba8b1696c7f447a13c464f
https://doi.org/10.1161/circulationaha.119.038376

المؤلفون: Tara A. Burns, Aimee L. Phelps, John Bullard, Russell A. Norris, Emilye Hiriart, Katelynn Toomer, Andy Wessels, Raymond N. Deepe, Courtney J. Haycraft

المصدر: The Anatomical Record. 302:136-145

مصطلحات موضوعية: Male, 0301 basic medicine, Cell type, Histology, Penetrance, Heart Septal Defects, Atrial, Article, Total anomalous pulmonary venous return, Mice, 03 medical and health sciences, 0302 clinical medicine, Intraflagellar transport, Double outlet right ventricle, Animals, Medicine, Cilia, Atrioventricular Septal Defect, Ecology, Evolution, Behavior and Systematics, Mice, Knockout, Heart development, MEF2 Transcription Factors, business.industry, Tumor Suppressor Proteins, Cilium, Scimitar Syndrome, Anatomy, medicine.disease, Disease Models, Animal, Collagen Type III, 030104 developmental biology, Pulmonary Veins, business, 030217 neurology & neurosurgery, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f189e23d77c415a4a7c443b5246687
https://doi.org/10.1002/ar.23909

المؤلفون: Christina Wang, Kelsey Moore, Katelynn Toomer, Cortney Gensemer, Colin T. McDowell, Russell A. Norris, Tyler Beck, Justin Bian, Joshua H. Lipschutz, Marie-Ange Renault, Mary Kate Rumph, Sameer Abrol, Rebecca Stairley, Diana Fulmer, Reece Moore, Janiece Glover, Faith Emetu, Andy Wessels, Lilong Guo

المساهمون: Medical University of South Carolina [Charleston] (MUSC), Biologie des maladies cardiovasculaires = Biology of Cardiovascular Diseases, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Bordeaux (UB)-Centre National de la Recherche Scientifique (CNRS), Admin, Oskar, Université de Bordeaux (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Developmental Biology
Developmental Biology, Elsevier, 2020, 463 (1), pp.26-38. ⟨10.1016/j.ydbio.2020.03.003⟩
Developmental Biology, 2020, 463 (1), pp.26-38. ⟨10.1016/j.ydbio.2020.03.003⟩
Dev Biol

مصطلحات موضوعية: rac1 GTP-Binding Protein, Population, Myocytes, Smooth Muscle, Heart Valve Diseases, Biology, Article, 03 medical and health sciences, Paracrine signalling, Mice, 0302 clinical medicine, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Smooth Muscle, Mitral valve, medicine, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, Mitral valve prolapse, Animals, Hedgehog Proteins, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Cilia, education, Molecular Biology, Desert hedgehog, 030304 developmental biology, 0303 health sciences, education.field_of_study, Myocytes, Mitral Valve Prolapse, Cilium, Neuropeptides, Muscle, Smooth, Cell Biology, medicine.disease, Hedgehog signaling pathway, Actins, Cell biology, [SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Extracellular Matrix, medicine.anatomical_structure, Phenotype, Mitral Valve, Muscle, Smooth, Smoothened, 030217 neurology & neurosurgery, Developmental Biology, Signal Transduction, Transcription Factors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ed85d7f4475602e4ba1be541174d13
https://hal.archives-ouvertes.fr/hal-03159130

المؤلفون: Jia Jia, Robert C. Coyle, Donald R. Menick, Dylan J. Richards, Yu Tan, Kerri Wong, Ying Mei, Katelynn Toomer

المصدر: Biomaterials. 142:112-123

مصطلحات موضوعية: 0301 basic medicine, Cell type, Cell, Biophysics, Bioengineering, Embryoid body, Biology, Regenerative medicine, Article, Biomaterials, Cell therapy, 03 medical and health sciences, Biomimetics, Human Umbilical Vein Endothelial Cells, Organoid, medicine, Humans, Myocytes, Cardiac, Heart development, Stem Cells, Heart, Coronary vasculogenesis, Extracellular Matrix, Organoids, Phenotype, 030104 developmental biology, medicine.anatomical_structure, Adipose Tissue, Mechanics of Materials, Ceramics and Composites, Neuroscience, Biomedical engineering

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e06aec43d1cd1fd80ba9d099772ec48
https://doi.org/10.1016/j.biomaterials.2017.07.021

المؤلفون: Russell A. Norris, Brittany Brooks, Paige Swanson, Neal Peterson, Rupak Mukherjee, Lilong Guo, Diana Fulmer, Alex Drohan, Joshua H. Lipschutz, Katelynn Toomer, Andy Wessels, Simon C. Body

المصدر: Developmental Dynamics. 246:625-634

مصطلحات موضوعية: 0301 basic medicine, Aortic valve, Pathology, medicine.medical_specialty, education.field_of_study, Cilium, Population, Anatomy, Disease, Biology, medicine.disease, Phenotype, Ciliopathies, Extracellular matrix, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Bicuspid aortic valve, medicine, education, 030217 neurology & neurosurgery, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d7dc5dbd353292101145c94fa86978fb
https://doi.org/10.1002/dvdy.24524

المؤلفون: Kelsey Moore, Russell A. Norris, Francesca N. Delling, Reece Moore, Ka’la D. Drayton, Roger R. Markwald, Peter Kohl, Willian A. da Silveira, Simon C. Body, Neal Peterson, Solena Le Scouarnec, Janiece Glover, Eva A. Rog-Zielinska, E. Starr Hazard, Katelynn Toomer, Susan A. Slaugenhaupt, Jean-Jacques Schott, David J. Milan, Breiona J. Catching, Ronen Durst, Alex Drohan, Lilong Guo, Federica del Monte, Harrison Brand, Patrick T. Ellinor, Nabila Bouatia-Naji, Thierry Le Tourneau, Diana Fulmer, Joshua H. Lipschutz, Xavier Jeunemaitre, Albert Hagège, Rupak Mukherjee, Christian Dina, Baolin Wang, Ryan L. Collins, Rebecca Stairley, Mengyao Yu, Robert A. Levine, Michael E. Talkowski, Sandra Ramos-Ortiz, Maire Leyne, Alexander Awgulewitsch, Andy Wessels, Gary Hardiman

المصدر: Toomer, K A, Yu, M, Fulmer, D, Guo, L, Moore, K S, Moore, R, Drayton, K D, Glover, J, Peterson, N, Ramos-Ortiz, S, Drohan, A, Catching, B J, Stairley, R, Wessels, A, Lipschutz, J H, Delling, F N, Jeunemaitre, X, Dina, C, Collins, R L, Brand, H, Talkowski, M E, Del Monte, F, Mukherjee, R, Awgulewitsch, A, Body, S, Hardiman, G, Hazard, E S, da Silveira, W A, Wang, B, Leyne, M, Durst, R, Markwald, R R, Le Scouarnec, S, Hagege, A, Le Tourneau, T, Kohl, P, Rog-Zielinska, E A, Ellinor, P T, Levine, R A, Milan, D J, Schott, J-J, Bouatia-Naji, N, Slaugenhaupt, S A & Norris, R A 2019, ' Primary cilia defects causing mitral valve prolapse ', Science Translational Medicine, vol. 11, no. 493, eaax0290 . https://doi.org/10.1126/scitranslmed.aax0290
Sci Transl Med

مصطلحات موضوعية: Male, 0301 basic medicine, Pathology, medicine.medical_specialty, Time Factors, Genome-wide association study, 030204 cardiovascular system & hematology, Myxomatous degeneration, Article, Sudden cardiac death, Extracellular matrix, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Ciliogenesis, Mitral valve, Morphogenesis, medicine, Animals, Humans, Mitral valve prolapse, Missense mutation, cardiovascular diseases, Cilia, Adaptor Proteins, Signal Transducing, Mice, Knockout, Mitral Valve Prolapse, Base Sequence, business.industry, Tumor Suppressor Proteins, Cilium, Mitral Valve Insufficiency, General Medicine, medicine.disease, Heart Valves, Extracellular Matrix, Pedigree, 030104 developmental biology, medicine.anatomical_structure, Echocardiography, cardiovascular system, Cardiology, Female, Cardiology and Cardiovascular Medicine, business, Genome-Wide Association Study

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a0e7dc0197365d4ec46d9e34016737
https://doi.org/10.1126/scitranslmed.aax0290

المؤلفون: Russell A. Norris, Katelynn Toomer, Kelsey Moore, Janiece Glover, Diana Fulmer, Joyce Bischoff, Kimberly Sauls, Rebecca Stairley, Lilong Guo, Robert A. Levine

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Male, Histology, Filamins, Organogenesis, Population, SMAD, Biology, Filamin, Article, Extracellular matrix, 03 medical and health sciences, Mice, 0302 clinical medicine, Mitral valve, medicine, Mitral valve prolapse, FLNA, Animals, Smad3 Protein, education, Ecology, Evolution, Behavior and Systematics, Mice, Knockout, education.field_of_study, Mitogen-Activated Protein Kinase 3, medicine.disease, Cell biology, Extracellular Matrix, 030104 developmental biology, medicine.anatomical_structure, Phenotype, Mitral Valve, Female, Anatomy, 030217 neurology & neurosurgery, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bad05a886a0d2dd69809ce87e304d749
https://europepmc.org/articles/PMC6312478/

المؤلفون: Yaopan Mao, Katelynn Toomer, Charles Simpson, David J. Milan, David S. Peal, Francesca N. Delling, Roger R. Markwald, Jorge Solis, Maelle Perrocheau, Ronen Durst, Lisa A. Freed, Amanda J. Johnson, Annemarieke DeVlaming, Christopher Jett, Xavier Estivill, Leticia Fernández-Friera, Adrian H. Chester, Michel Pucéat, Matthew R. Stone, Maire Leyne, Thierry Le Tourneau, Susan A. Slaugenhaupt, Christian Dina, Jean-Jacques Schott, Monica Salani, Kenneth D. Irvine, Katherine Williams, Kimberly Sauls, Andy Wessels, Yoshikazu Tsukasaki, Daniel Trujillano, Xingju Nie, Herve LeMarec, Florie A. Charles, Patrick Bruneval, Donald R. Menick, Robert A. Levine, Stephan Ossowski, Russell A. Norris, Michael E. Talkowski, Harinath Kasiganesan, Nabila Bouatia-Naji, Ann-Marie Broome, Stacey N. Lynch, Tahirali Motiwala, Harrison Brand, Christophe Tribouilloy, Colby Chiang, Albert Hagège, Xavier Jeunemaitre

المساهمون: Center for humana genetic research, Harvard Medical School [Boston] (HMS), Dipartimento di Biologia Cellulare e dello Sviluppo, Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA), Paris-Centre de Recherche Cardiovasculaire (PARCC - UMR-S U970), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Mécanismes physiologiques et conséquences des calcifications cardiovasculaires: rôle des remodelages cardiovasculaires et osseux, Université de Picardie Jules Verne (UPJV)-Institut National de la Santé et de la Recherche Médicale (INSERM), Unité de recherche de l'institut du thorax (ITX-lab), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN), Laser Processing Group, Center for Genomic Regulation (CRG-UPF), CIBER de Epidemiología y Salud Pública (CIBERESP), Laboratoire de Recherche en Imagerie : Méthodes d'imagerie des Échanges transcapillaires (LRI - EA4062), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Génétique Médicale et Génomique Fonctionnelle (GMGF), Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université Paris Descartes - Paris 5 (UPD5), Service de cardiologie [CHU HEGP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), unité de recherche de l'institut du thorax UMR1087 UMR6291 (ITX), Università degli Studi di Roma 'La Sapienza' [Rome], Université Paris Descartes - Paris 5 (UPD5)-Hôpital Européen Georges Pompidou [APHP] (HEGP), Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Descartes - Paris 5 (UPD5), Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpital Européen Georges Pompidou [APHP] (HEGP), Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)

المصدر: Nature
Nature, 2015, Equipe 3, 525 (7567), pp.109--113. ⟨10.1038/nature14670⟩
Nature, Nature Publishing Group, 2015, Equipe 3, 525 (7567), pp.109--113. ⟨10.1038/nature14670⟩

مصطلحات موضوعية: Male, Pathology, medicine.medical_treatment, [SDV]Life Sciences [q-bio], Messenger, 030204 cardiovascular system & hematology, medicine.disease_cause, Mice, 0302 clinical medicine, Cell Movement, Mitral valve, Missense mutation, Mitral valve prolapse, Atrioventricular canal defect, Pair 11, Zebrafish, Genetics, 0303 health sciences, Mutation, Multidisciplinary, Mitral Valve Prolapse, Protein Stability, Cadherins, 3. Good health, Pedigree, medicine.anatomical_structure, Phenotype, cardiovascular system, Mitral Valve, Female, Human, medicine.medical_specialty, Cadherin Related Proteins, Biology, Chromosomes, Article, 03 medical and health sciences, medicine, Animals, Humans, RNA, Messenger, 030304 developmental biology, Body Patterning, Mitral regurgitation, Mitral valve repair, DCHS1, Chromosomes, Human, Pair 11, Zebrafish Proteins, medicine.disease, RNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6591f59e92317fa7a60159dfd5e0c478
http://europepmc.org/articles/PMC4720389