نتائج البحث - "Katherine E. Harris"

1

دورية أكاديمية

A T-cell engaging bispecific antibody with a tumor-selective bivalent folate receptor alpha binding arm for the treatment of ovarian cancer

المصدر: OncoImmunology, Vol 11, Iss 1 (2022)

مصطلحات موضوعية: Bispecific antibody, T-cell engager, folate receptor alpha, ovarian cancer, on-target, off-tumor toxicity, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2162-402X

URL الوصول: https://doaj.org/article/9e96f15bb0a54d7bb137adf3be604c3c

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2

دورية أكاديمية

A bispecific antibody agonist of the IL-2 heterodimeric receptor preferentially promotes in vivo expansion of CD8 and NK cells

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/6280e71ffa694c31a509b1afcf87bff2

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3

دورية أكاديمية

TNB-486 induces potent tumor cell cytotoxicity coupled with low cytokine release in preclinical models of B-NHL

المؤلفون: Harbani K. Malik-Chaudhry, Kirthana Prabhakar, Harshad S. Ugamraj, Andrew A. Boudreau, Benjamin Buelow, Kevin Dang, Laura M. Davison, Katherine E. Harris, Brett Jorgensen, Heather Ogana, Duy Pham, Ute Schellenberger, Wim Van Schooten, Roland Buelow, Suhasini Iyer, Nathan D. Trinklein, Udaya S. Rangaswamy

المصدر: mAbs, Vol 13, Iss 1 (2021)

مصطلحات موضوعية: Bispecific antibody, T-cell engager, CD19XCD3, cytokine release syndrome, TNB-486, low cytokine release, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1942-0862; https://doaj.org/toc/1942-0870

URL الوصول: https://doaj.org/article/54c6dadc1dc04e3c82d81639cfba9a39

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4

دورية أكاديمية

Multispecific Antibody Development Platform Based on Human Heavy Chain Antibodies

المصدر: Frontiers in Immunology, Vol 9 (2019)

مصطلحات موضوعية: heavy chain antibodies, VH domains, domain antibodies, antibody discovery platform, next-generation sequencing, repertoire sequencing, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2018.03037/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/6a706cdfcb4649ab82279f4b31c5c13b

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5

دورية أكاديمية

Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies

المصدر: Frontiers in Immunology, Vol 9 (2018)

مصطلحات موضوعية: monoclonal human antibodies, transgenic rodent, rearranged light chain, somatic hypermutation, deep sequencing, antibody repertoire, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fimmu.2018.00889/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/0e55864017b746d182977ff0f5e8bf28

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nab-Sirolimus for Patients With Malignant Perivascular Epithelioid Cell Tumors

المؤلفون: Katherine E. Harris, Berta Grigorian, Anita N. Schmid, Rashmi Chugh, Andrew J. Wagner, Shihe Hou, Neil P. Desai, Mark A. Dickson, Kristen N. Ganjoo, Vinod Ravi, Brian A. Van Tine, Lee D. Cranmer, Jason L. Hornick, Richard F. Riedel, Erlinda M. Gordon, Heng Du, David J. Kwiatkowski

المصدر: Journal of Clinical Oncology. 39:3660-3670

مصطلحات موضوعية: Perivascular Epithelioid Cell Tumors, Cancer Research, Pathology, medicine.medical_specialty, Oncology, business.industry, Sirolimus, medicine, Sarcoma, medicine.disease, business, Perivascular Epithelioid Cell, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bf81d53afe8152f908842cfd4492123d
https://doi.org/10.1200/jco.21.01728

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Abstract 6244: A T cell engaging bispecific antibody utilizing a bivalent tumor-selective folate receptor alpha binding arm for the treatment of ovarian cancer

المصدر: Cancer Research. 82:6244-6244

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::974cc1fe5dfb81ca04c3aeb8b9256dba
https://doi.org/10.1158/1538-7445.am2022-6244

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TNB-486 induces potent tumor cell cytotoxicity coupled with low cytokine release in preclinical models of B-NHL

المؤلفون: Suhasini Iyer, Roland Buelow, Udaya Rangaswamy, Harbani K. Malik-Chaudhry, Kevin Dang, Katherine E. Harris, Duy Pham, Nathan D. Trinklein, Benjamin Buelow, Andrew Boudreau, Harshad Ugamraj, Brett Jorgensen, Wim Van Schooten, Heather Ogana, Laura Davison, Ute Schellenberger, Kirthana Prabhakar

المصدر: mAbs
article-version (VoR) Version of Record

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Cytotoxicity, Immunologic, Bispecific antibody, CD3 Complex, medicine.medical_treatment, Mice, SCID, CD8-Positive T-Lymphocytes, Lymphocyte Activation, 0302 clinical medicine, Antineoplastic Agents, Immunological, Mice, Inbred NOD, hemic and lymphatic diseases, Antibodies, Bispecific, Immunology and Allergy, Cytotoxicity, CD19XCD3, 0303 health sciences, Mice, Inbred BALB C, biology, Lymphoma, Non-Hodgkin, TNB-486, Cytokine release syndrome, Cytokine, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cytokines, Immunology, Antigens, CD19, Tumor cells, Antibodies, Monoclonal, Humanized, CD19, 03 medical and health sciences, Report, medicine, Animals, Humans, B cell, 030304 developmental biology, business.industry, T-cell engager, cytokine release syndrome, Immunotherapy, medicine.disease, Xenograft Model Antitumor Assays, Coculture Techniques, Macaca fascicularis, Cancer research, biology.protein, business, low cytokine release, K562 Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d92f1f9c2ff2b785bb25ed73b0b3686
http://europepmc.org/articles/PMC8023237

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9

Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies

المؤلفون: Harshad Ugamraj, Shelley Force Aldred, Katherine E. Harris, Suhasini Iyer, Brett Jorgensen, Payal Pratap, Ute Schellenberger, Kevin Dang, Nathan D. Trinklein, Omid Vafa, Starlynn Clarke, Udaya Rangaswamy, Duy Pham, Andrew Boudreau, Arun P. Wiita, Wim Van Schooten, Roland Buelow, Ben Buelow, Priya Choudhry

المصدر: mAbs

مصطلحات موضوعية: Cytotoxicity, Immunologic, T cell engager, CD3 Complex, T-Lymphocytes, Bispecific antibody, medicine.medical_treatment, Lymphocyte Activation, Epitope, Jurkat Cells, Mice, 0302 clinical medicine, Neoplasms, Antibodies, Bispecific, Immunology and Allergy, Cytotoxicity, 0303 health sciences, biology, Chemistry, repertoire, Antibodies, Monoclonal, 3. Good health, multiple myeloma, Cytokine, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cytokines, Female, Antibody, Animals, Inbred Strains, Agonist, medicine.drug_class, CD3, T cell, Immunology, T cells, deep sequencing, 03 medical and health sciences, Antigens, Neoplasm, Report, medicine, Animals, Humans, 030304 developmental biology, Xenograft Model Antitumor Assays, In vitro, Rats, BCMA, Cancer research, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4b184b5d3178df107b003f6357e3f4
https://doi.org/10.1080/19420862.2019.1574521

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10

A bispecific antibody agonist of the IL-2 heterodimeric receptor preferentially promotes in vivo expansion of CD8 and NK cells

المصدر: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90d894a3e82ef93863d71f6ca4cad8dd
https://pubmed.ncbi.nlm.nih.gov/34011961

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