-
1دورية أكاديمية
المؤلفون: Marion Vanneste, Charlotte R. Feddersen, Afshin Varzavand, Elliot Y. Zhu, Tyler Foley, Lei Zhao, Kathleen H. Holt, Mohammed Milhem, Robert Piper, Christopher S. Stipp, Adam J. Dupuy, Michael D. Henry
المصدر: Frontiers in Oncology, Vol 10 (2020)
مصطلحات موضوعية: melanoma, forward genetic screen, MAPKi resistance, CUL3 ubiquitin ligase, Rac1, Src inhibitor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
-
2
المصدر: Ebolaviruses ISBN: 9781493971152
مصطلحات موضوعية: 0301 basic medicine, Genetic Vectors, Transfection, Article, Viral vector, 03 medical and health sciences, 0302 clinical medicine, Viral Envelope Proteins, Viral entry, Animals, Humans, Vector (molecular biology), chemistry.chemical_classification, Expression vector, Membrane Glycoproteins, biology, Lentivirus, Genetic Therapy, Virus Internalization, Marburgvirus, biology.organism_classification, Virology, Viral Tropism, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Pseudotyping, Glycoprotein, Plasmids
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a6c2292e3c414c5318521e358a189d
https://pubmed.ncbi.nlm.nih.gov/28573611 -
3
المؤلفون: Paul J. Godowski, Tamas Oravecz, Deanna Grant, Brian Zambrowicz, Nico Ghilardi, Dennis S. Rice, Weilan Ye, Mark J. Solloway, Wei Yu Lin, Kathleen H. Holt, Jerry Tang, Gwenn M. Hansen, Derek E. Eberhart, Tracy Tang, Yun Li, Flavius Martin, William F. Forrest, Alejandro Abuin, Frederic J. de Sauvage, Andrew S. Peterson, Li Li, Leon Parker, Kenneth A. Platt
المصدر: Nature Biotechnology. 28:749-755
مصطلحات موضوعية: Mice, Knockout, Genetics, Mutation, Phenotypic screening, Mutant, Biomedical Engineering, Membrane Proteins, Bioengineering, Biology, medicine.disease_cause, Applied Microbiology and Biotechnology, Transmembrane protein, Mice, Membrane protein, Knockout mouse, medicine, Animals, Molecular Medicine, Homologous recombination, Gene, Biotechnology
-
4
المصدر: Trends in Biotechnology. 20:36-42
مصطلحات موضوعية: Male, Mammalian Genetics, Drug Evaluation, Preclinical, Chemical biology, Mutagenesis (molecular biology technique), Mice, Transgenic, Bioengineering, Biology, Genome, Mice, Animals, Humans, Genetic Testing, Gene, Genetics, Genome, Human, Drug discovery, Chemical Engineering, Phenotype, Mutagenesis, Drug Design, Gene Targeting, Models, Animal, Female, Human genome, Genetic Engineering, Function (biology), Forecasting, Biotechnology
-
5
المؤلفون: Kathleen H. Holt, Kevin P. Campbell, Rachelle H. Crosbie, David Venzke
المصدر: FEBS Letters. 468:79-83
مصطلحات موضوعية: Glycosylation, Cytomegalovirus, Oligosaccharides, Biochemistry, chemistry.chemical_compound, 0302 clinical medicine, Structural Biology, Cricetinae, Chinese hamster ovary cell, Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase, Dystroglycan, Dystroglycans, Peptide sequence, 0303 health sciences, Membrane Glycoproteins, Tunicamycin, Transfection, musculoskeletal system, Electrophoresis, Polyacrylamide Gel, Rabbits, tissues, musculoskeletal diseases, congenital, hereditary, and neonatal diseases and abnormalities, animal structures, Genetic Vectors, Immunoblotting, Molecular Sequence Data, Biophysics, CHO Cells, Biology, Cleavage (embryo), Amidohydrolases, 03 medical and health sciences, Genetics, Animals, Amino Acid Sequence, RNA, Messenger, Protein Precursors, Dystrophin–glycoprotein complex, Protein precursor, Molecular Biology, 030304 developmental biology, Cell Membrane, Cell Biology, Molecular Weight, Cytoskeletal Proteins, chemistry, Culture Media, Conditioned, biology.protein, Pikachurin, Peptides, Protein Processing, Post-Translational, 030217 neurology & neurosurgery
-
6
المؤلفون: Jack H. Van Der Meulen, Steven A. Moore, Kathleen H. Holt, Connie S. Lebakken, Leland E. Lim, Kevin P. Campbell, David Venzke, Audrey J. Ettinger, Franck Duclos, Rachelle H. Crosbie, Madeleine Durbeej, John A. Faulkner, Roger A. Williamson, Joshua R. Sanes, Ron F. Hrstka, Volker Straub, Beverly L. Davidson
المصدر: The Journal of Cell Biology
مصطلحات موضوعية: gene targeting, Sarcospan, Dystrophin, Mice, Sarcolemma, 0302 clinical medicine, Muscular dystrophy, Mice, Knockout, 0303 health sciences, Membrane Glycoproteins, Gene Transfer Techniques, musculoskeletal system, Neoplasm Proteins, Sarcoglycan, Disease Progression, medicine.symptom, ITGA7, Muscle Contraction, Muscle contraction, muscular dystrophy, musculoskeletal diseases, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, DNA, Complementary, Molecular Sequence Data, Biology, dystroglycan, 03 medical and health sciences, Sarcoglycans, Internal medicine, sarcoglycan, medicine, Animals, Amino Acid Sequence, Glycoproteins, 030304 developmental biology, SGCA, Base Sequence, Membrane Proteins, Cell Biology, Muscular Dystrophy, Animal, medicine.disease, Molecular biology, Mice, Inbred C57BL, Cytoskeletal Proteins, Endocrinology, biology.protein, sarcospan, Carrier Proteins, 030217 neurology & neurosurgery, Regular Articles
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6840e07b9dc703cbad7400589d624bfc
https://doi.org/10.1083/jcb.142.6.1461 -
7SOS Phosphorylation and Disassociation of the Grb2-SOS Complex by the ERK and JNK Signaling Pathways
المؤلفون: Jeffrey E. Pessin, Steven B. Waters, Dong Chen, Kathleen H. Holt
المصدر: Journal of Biological Chemistry. 271:6328-6332
مصطلحات موضوعية: MAPK/ERK pathway, medicine.medical_treatment, Nerve Tissue Proteins, CHO Cells, Biology, Biochemistry, Feedback, Mice, chemistry.chemical_compound, Osmotic Pressure, Cricetinae, medicine, Animals, Guanine Nucleotide Exchange Factors, Humans, Insulin, Grb2-Sos complex, Phosphorylation, Molecular Biology, Anisomycin, Adaptor Proteins, Signal Transducing, GRB2 Adaptor Protein, Kinase, MEK inhibitor, JNK Mitogen-Activated Protein Kinases, Proteins, Cell Biology, Receptor, Insulin, Cell biology, enzymes and coenzymes (carbohydrates), chemistry, Calcium-Calmodulin-Dependent Protein Kinases, ras Proteins, bacteria, ras Guanine Nucleotide Exchange Factors, Mitogen-Activated Protein Kinases, Signal transduction, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7243bf2d6967193642513cdeae8b2fb
https://doi.org/10.1074/jbc.271.11.6328 -
8
المؤلفون: Kathleen H. Holt, Jeffrey E. Pessin, Barry G. Kasson
المصدر: Molecular and Cellular Biology. 16:577-583
مصطلحات موضوعية: MAPK/ERK pathway, MAP Kinase Kinase Kinase 1, Cell Cycle Proteins, Nerve Tissue Proteins, CHO Cells, Protein Serine-Threonine Kinases, Biology, Mitogen-activated protein kinase kinase, Models, Biological, Immediate-Early Proteins, MAP2K7, Cricetinae, Protein Phosphatase 1, Phosphoprotein Phosphatases, Animals, Humans, Insulin, ASK1, c-Raf, Phosphorylation, Protein kinase A, Molecular Biology, Adaptor Proteins, Signal Transducing, GRB2 Adaptor Protein, MAP kinase kinase kinase, Cyclin-dependent kinase 2, Membrane Proteins, Proteins, Dual Specificity Phosphatase 1, Cell Biology, Molecular biology, Receptor, Insulin, Recombinant Proteins, Cell biology, enzymes and coenzymes (carbohydrates), Son of Sevenless Proteins, biology.protein, bacteria, Mitogen-Activated Protein Kinases, Protein Tyrosine Phosphatases, Signal Transduction, Research Article
-
9
المؤلفون: Jeffrey E. Pessin, Kathleen H. Holt, W S Moye-Rowley, L Olson
المصدر: Molecular and Cellular Biology. 14:42-49
مصطلحات موضوعية: animal structures, Protein Conformation, Recombinant Fusion Proteins, Protein subunit, Genes, Fungal, Molecular Sequence Data, Gene Expression, Peptide binding, Saccharomyces cerevisiae, macromolecular substances, Biology, SH2 domain, Phosphatidylinositol 3-Kinases, Transactivation, Protein structure, Genes, Reporter, Amino Acid Sequence, DNA, Fungal, Molecular Biology, Peptide sequence, Sequence Deletion, Cell Biology, DNA-binding domain, beta-Galactosidase, musculoskeletal system, Cell biology, Enzyme Activation, Phosphotransferases (Alcohol Group Acceptor), enzymes and coenzymes (carbohydrates), Biochemistry, Phosphotyrosine-binding domain, hormones, hormone substitutes, and hormone antagonists, Research Article
-
10
المؤلفون: Keishi Yamauchi, Jeffrey E. Pessin, Kathleen H. Holt
المصدر: Journal of Biological Chemistry. 268:14597-14600
مصطلحات موضوعية: biology, Kinase, Insulin, medicine.medical_treatment, Chinese hamster ovary cell, Cell Biology, Serum Response Element, Biochemistry, Molecular biology, Insulin receptor, chemistry.chemical_compound, chemistry, Transcription (biology), biology.protein, medicine, Phosphatidylinositol, Signal transduction, Molecular Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cf01df996fe14d86040c0be8dbb82887
https://doi.org/10.1016/s0021-9258(18)82374-2
Full Text Finder 
PDF full text from Publisher