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المؤلفون: Kevin J. Tomaselli, Julia Herrmann, Robert O. Sayers, Joe C. Wu, Lalitha Kodandapani, Kathy G. Jahangiri, Craig D. Fisher, David T. Winn, Edward D. Robinson, Steven P. Meduna, Robert J. Ternansky, Pauline Yeo, Karen L. Valentino, Jose-Luis Diaz, Vincent J. Kalish, Steven D. Linton, Kristen Sebring, Robert A. Armstrong, Joseph F. Krebs, Niel C. Hoglen, Alfred P. Spada, Brad P. Hirakawa, Ning Chen, Brett R. Ullman, Brett Weylan Ching, Cheng-zhi Zhang, Xu Bai, Xin Gu, Kip Nalley, Long-Shiuh Chen, Patricia L. Gladstone, Jeff McQuiston, Teresa Aja, Todd Groessl, Donald S. Karanewsky, Suzanne Weeks, Lawrence C. Fritz, Patricia C. Contreras
المصدر: Journal of Medicinal Chemistry. 48:6779-6782
مصطلحات موضوعية: Adult, Biological Availability, Phases of clinical research, Apoptosis, Pharmacology, Jurkat Cells, Mice, Structure-Activity Relationship, Liver disease, Pharmacokinetics, In vivo, Drug Discovery, medicine, Animals, Humans, Aspartate Aminotransferases, Pentanoic Acids, Caspase, Liver injury, Cholestasis, Clinical Trials, Phase I as Topic, biology, Caspase 3, Chemistry, Liver Diseases, Alanine Transaminase, Hepatitis C, Chronic, medicine.disease, Caspase Inhibitors, In vitro, Rats, Liver, Biochemistry, Enzyme inhibitor, Hepatocytes, biology.protein, Molecular Medicine, Half-Life
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المؤلفون: Kathy G. Jahangiri, Michael K. Dalton, Haiji Xia, Jeffrey R. Hammaker, Azra Pervin, Alexandre V. Ivachtchenko, Frederick J. Lakner, Alexander Viktorovich Khvat, Alexander S. Kiselyov
المصدر: Tetrahedron Letters. 46:5325-5328
مصطلحات موضوعية: chemistry.chemical_classification, Stereochemistry, Organic Chemistry, Mesoionic, Thio, Ring (chemistry), Biochemistry, Amino acid, chemistry.chemical_compound, chemistry, Yield (chemistry), Drug Discovery, Microwave irradiation, X ray analysis
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المؤلفون: Robert Smidt, Silvio Roggo, Julia Herrmann, Edward D. Robinson, Kathy G. Jahangiri, Teresa Aja, Kip Nalley, Thomas L. Deckwerth, Giorgio Rovelli, Kevin J. Tomaselli, Joe C. Wu, Bastian Hengerer, Steven P. Meduna, André Sauter, Jose-Luis Diaz, Joerg Kallen, Albert Schmitz, Donald S. Karanewsky, Brett R. Ullman, Steven D. Linton, Christoph Wiessner, Robert J. Ternansky, Peter R. Allegrini, Robert O. Sayers
المصدر: Bioorganic & Medicinal Chemistry Letters. 14:2685-2691
مصطلحات موضوعية: Peptidomimetic, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Oxamyl, Apoptosis, Peptide, Biochemistry, Cell Line, Inhibitory Concentration 50, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Humans, Structure–activity relationship, Molecular Biology, Caspase, chemistry.chemical_classification, Dipeptide, biology, Organic Chemistry, Neurodegenerative Diseases, Dipeptides, Caspase Inhibitors, In vitro, Stroke, Kinetics, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Carbamates
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المؤلفون: Xian Guo, Robert J. Ternansky, Brett R. Ullman, Lawrence C. Fritz, Robert Smidt, Ning Chen, Albert Schmitz, Lalitha Kodandapani, Donald S. Karanewsky, Jose-Luis Diaz, Steven D. Linton, Vincent J. Kalish, Brian Pham, U. von Krosigk, Kathy G. Jahangiri, Kevin J. Tomaselli, Steven P. Meduna, Joe C. Wu, Silvio Roggo, Edward D. Robinson
المصدر: Bioorganicmedicinal chemistry letters. 12(20)
مصطلحات موضوعية: Stereochemistry, medicine.drug_class, Acylation, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Caspase 8, Biochemistry, Chemical synthesis, Structure-Activity Relationship, Drug Discovery, medicine, Enzyme Inhibitors, Molecular Biology, Caspase, chemistry.chemical_classification, biology, Organic Chemistry, Dipeptides, Caspase Inhibitors, In vitro, Isoenzymes, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Indicators and Reagents, Oligopeptides, Lactone
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