المؤلفون: Julia Sachs, Katja Döhl, Anja Weber, Michele Bonus, Ferdinand Ehlers, Edmond Fleischer, Anette Klinger, Holger Gohlke, Jörg Pietruszka, Lutz Schmitt, Nicole Teusch

المصدر: Frontiers in Pharmacology, Vol 10 (2019)

مصطلحات موضوعية: multidrug resistance, cancer chemotherapy, 4-dihydroisocoumarin, P-glycoprotein, breast cancer resistance protein, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphar.2019.00400/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/34ae5ab8192f4c63aca732d51ee02abb

المؤلفون: Lutz Schmitt, Anja C. M. Nordschild, Anja Weber, Thomas Fischer, Andrea Kulik, Nicole Teusch, Jörg Pietruszka, Dennis Schröder, Katja Döhl, Julia Sachs

المصدر: Bioorganic & Medicinal Chemistry. 25:6115-6125

مصطلحات موضوعية: Double bond, Cell Survival, Stereochemistry, Clinical Biochemistry, Substituent, Pharmaceutical Science, Antineoplastic Agents, Stereoisomerism, 010402 general chemistry, 01 natural sciences, Biochemistry, Lactones, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Cell Line, Tumor, Drug Discovery, Humans, Structure–activity relationship, Cytotoxicity, Molecular Biology, chemistry.chemical_classification, Natural product, 010405 organic chemistry, Chemistry, Organic Chemistry, 0104 chemical sciences, A549 Cells, Pyrones, MCF-7 Cells, Molecular Medicine, Stereoselectivity, Drug Screening Assays, Antitumor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d10ac52fec8877f2e58f1f959f9f38f
https://doi.org/10.1016/j.bmc.2017.02.004

المؤلفون: Lutz Schmitt, Holger Gohlke, Katja Döhl, Edmond Fleischer, Julia Sachs, Anette Klinger, Michele Bonus, Anja Weber, Ferdinand Ehlers, Nicole Teusch, Jörg Pietruszka

المصدر: Frontiers in Pharmacology, Vol 10 (2019)
Frontiers in pharmacology 10, 400 (2019). doi:10.3389/fphar.2019.00400
Frontiers in Pharmacology

مصطلحات موضوعية: P-Glykoprotein, 0301 basic medicine, Abcg2, ATP-binding cassette transporter, P-glycoprotein, cancer chemotherapy, 03 medical and health sciences, 0302 clinical medicine, multidrug resistance, Pdr5, Brustkrebs, Pharmacology (medical), ddc:610, Chemotherapie, Cytotoxicity, Original Research, Pharmacology, ddc:615, Multidrug-Resistenz, biology, Chemistry, lcsh:RM1-950, Transporter, Multiple drug resistance, lcsh:Therapeutics. Pharmacology, 030104 developmental biology, 4-dihydroisocoumarin, Biochemistry, breast cancer resistance protein, 030220 oncology & carcinogenesis, biology.protein, Efflux, Intracellular

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ea5bf72ee04072f5d35dd30afb7205
https://doi.org/10.3389/fphar.2019.00400

المؤلفون: Soo Chan Lee, Anne-Claude Gingras, Joseph Heitman, Paola Coccetti, Corey Nislow, Karolina Niewola-Staszkowska, Ron Ammar, Katja Döhl, A. A. Leslie Gunatilaka, Anna F. Averette, Taeyup Kim, David R. Andes, Yong Sun Bahn, Lutz Schmitt, E. M. Kithsiri Wijeratne, G. M. Kamal B. Gunaherath, Frederick P. Roth, Dominique Sanglard, Leah E. Cowen, Robbie Loewith, Farida Tripodi, Tanvi Shekhar-Guturja, Jean-Philippe Lambert

المساهمون: Shekhar Guturja, T, Gunaherath, G, Wijeratne, E, Lambert, J, Averette, A, Lee, S, Kim, T, Bahn, Y, Tripodi, F, Ammar, R, Döhl, K, Niewola Staszkowska, K, Schmitt, L, Loewith, R, Proth, F, Sanglard, D, Andes, D, Nislow, C, Coccetti, P, Gingras, A, Heitman, J, Gunatilaka, A, Ecowen, L

المصدر: Nature chemical biology
Nature chemical biology, vol. 12, no. 10, pp. 867-875
Nature chemical biology, Vol. 12, No 10 (2016) pp. 867-875

مصطلحات موضوعية: 0301 basic medicine, Antifungal Agents, Mutant, Drug Resistance, Drug resistance, Antifungal Agents/chemistry/pharmacology, chemistry.chemical_compound, ddc:590, Signal Transduction/drug effects, Depsipeptides, Mycoses/drug therapy/microbiology, biology, Kinase, ATP-Binding Cassette Transporters/genetics, ATP-Binding Cassette Transporters/metabolism, Antifungal Agents/chemistry, Antifungal Agents/pharmacology, Depsipeptides/chemical synthesis, Depsipeptides/chemistry, Depsipeptides/pharmacology, Drug Resistance, Fungal/drug effects, Drug Resistance, Multiple/drug effects, Fungi/drug effects, Fungi/metabolism, HSP90 Heat-Shock Proteins/antagonists & inhibitors, HSP90 Heat-Shock Proteins/metabolism, Microbial Sensitivity Tests, Mycoses/drug therapy, Mycoses/microbiology, Protein Kinase Inhibitors/chemical synthesis, Protein Kinase Inhibitors/chemistry, Protein Kinase Inhibitors/pharmacology, Saccharomyces cerevisiae Proteins/genetics, Saccharomyces cerevisiae Proteins/metabolism, Small Molecule Libraries/chemistry, Small Molecule Libraries/pharmacology, TOR Serine-Threonine Kinases/antagonists & inhibitors, TOR Serine-Threonine Kinases/metabolism, TOR Serine-Threonine Kinases, Fungal/drug effects, BIO/11 - BIOLOGIA MOLECOLARE, Hsp90, BIO/10 - BIOCHIMICA, Drug Resistance, Multiple, 3. Good health, Biotinylation, Protein Kinase Inhibitors/chemical synthesis/chemistry/pharmacology, Efflux, Signal Transduction, Saccharomyces cerevisiae Proteins, 030106 microbiology, Saccharomyces cerevisiae Proteins/genetics/metabolism, Article, Microbiology, Fungi/drug effects/metabolism, Small Molecule Libraries, 03 medical and health sciences, Drug Resistance, Fungal, ddc:570, Small Molecule Libraries/chemistry/pharmacology, HSP90 Heat-Shock Proteins, Molecular Biology, Protein Kinase Inhibitors, Cell Biology, antifungal small molecule, CK2 pathway,TOR signaling, Fungi, Cell Biology, BIO/19 - MICROBIOLOGIA GENERALE, Depsipeptides/chemical synthesis/chemistry/pharmacology, TOR Serine-Threonine Kinases/antagonists & inhibitors/metabolism, Beauvericin, TOR signaling, 030104 developmental biology, chemistry, Mycoses, biology.protein, ATP-Binding Cassette Transporters/genetics/metabolism, HSP90 Heat-Shock Proteins/antagonists & inhibitors/metabolism, ATP-Binding Cassette Transporters, Multiple/drug effects

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df123ffb668df12b0d34f328ccb34f16
https://pubmed.ncbi.nlm.nih.gov/27571477

المؤلفون: Susanne Przybylla, Lutz Schmitt, Katja Döhl, Philipp Ellinger, Sander H. J. Smits, Marianne Kluth

المصدر: European Journal of Medical Research

مصطلحات موضوعية: chemistry.chemical_classification, biology, Calmodulin, ATPase, ATP-binding cassette transporter, General Medicine, Apical membrane, Molecular biology, Amino acid, Affinity chromatography, chemistry, Biochemistry, Cyclic nucleotide-binding domain, Radixin, Meeting Abstract, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3650f55e782de11fbffcafe099dfc2a9
http://europepmc.org/articles/PMC4118434