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1دورية أكاديمية
المؤلفون: Stephanie N. Liu, Priya Agarwal, Katja Heinig, Asim Datye, Carolina Sturm‐Pellanda, Andrea Crugnola, Marc Arca, Dale Miles
المصدر: Clinical and Translational Science, Vol 16, Iss 6, Pp 1085-1096 (2023)
مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270
وصف الملف: electronic resource
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2
المؤلفون: Katja Heinig, Filippo Sladojevich, Jeannine Petrig Schaffland, Georg Jaeschke, Alfred Ross, Philipp Koldewey, Saša M. Miladinović, Jin Wang, Caroline Rynn
المصدر: Pharmaceutical Research. 39:653-667
مصطلحات موضوعية: ErbB Receptors, Pharmacology, Kinetics, Organic Chemistry, Animals, Pharmaceutical Science, Molecular Medicine, Stereoisomerism, Pharmacology (medical), Rats, Wistar, Rats, Biotechnology
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3
المؤلفون: Agnès Poirier, Heidemarie Kletzl, Cordula Stillhart, Stephen Fowler, Kenichi Umehara, Andreas Guenther, Andreas Brink, Nicole A. Kratochwil, Dietrich Tuerck, Christophe Husser, Mark Savage, Mohammed Ullah, Lutz Mueller, Yumi Cleary, Katja Heinig
المصدر: Drug Metabolism and Disposition. 50:65-75
مصطلحات موضوعية: Pharmacology, Drug, Chemistry, In silico, media_common.quotation_subject, Pharmaceutical Science, Computational biology, Small molecule, Drug development, Pharmacokinetics, In vivo, Distribution (pharmacology), ADME, media_common
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a42eb9cb10d47b49d0cb86fb0a1206ac
https://doi.org/10.1124/dmd.121.000563 -
4
المؤلفون: Andrea Greiter-Wilke, Sonia Roberts, Katja Heinig, David Waiz, Roland Jenni, Henry Holzgrefe
المصدر: Journal of pharmacological and toxicological methods. 115
مصطلحات موضوعية: Pharmacology, Swine, Thioridazine, Toxicology, Autonomic Nervous System, Body Temperature, Electrocardiography, Long QT Syndrome, Macaca fascicularis, Dogs, Heart Rate, Animals, Swine, Miniature, Telemetry, Retrospective Studies
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5
المؤلفون: Stephen, Fowler, Andreas, Brink, Yumi, Cleary, Andreas, Günther, Katja, Heinig, Christophe, Husser, Heidemarie, Kletzl, Nicole, Kratochwil, Lutz, Mueller, Mark, Savage, Cordula, Stillhart, Dietrich, Tuerck, Mohammed, Ullah, Kenichi, Umehara, Agnès, Poirier
المصدر: Drug metabolism and disposition: the biological fate of chemicals. 50(1)
مصطلحات موضوعية: Survival of Motor Neuron 2 Protein, Pyrimidines, Pharmaceutical Preparations, RNA Splicing, Animals, Humans, Tissue Distribution, RNA, Messenger, In Vitro Techniques, Azo Compounds
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::4530dce338c940f32f354504129eb183
https://pubmed.ncbi.nlm.nih.gov/34620695 -
6
المؤلفون: Leon Aarons, Heidemarie Kletzl, Yumi Cleary, Michael Gertz, Andreas Günther, Katja Heinig, Aleksandra Galetin, Kayode Ogungbenro, Paul Grimsey
المصدر: Fukushima (Cleary), Y, Gertz, M, Grimsey, P, Günther, A, Heinig, K, Ogungbenro, K, Aarons, L, Galetin, A & Kletzl, H 2021, ' Model-based drug-drug interaction extrapolation strategy from adults to children – risdiplam in pediatric patients with spinal muscular atrophy ', Clinical Pharmacology & Therapeutics . https://doi.org/10.1002/cpt.2384
مصطلحات موضوعية: Adult, Male, Oncology, Physiologically based pharmacokinetic modelling, medicine.medical_specialty, Adolescent, CYP3A, Midazolam, Models, Biological, Muscular Atrophy, Spinal, Young Adult, Pharmacokinetics, In vivo, Internal medicine, Humans, Medicine, Drug Interactions, Pharmacology (medical), Child, Pharmacology, business.industry, Infant, Newborn, Area under the curve, Infant, Spinal muscular atrophy, SMA, medicine.disease, Pyrimidines, Neuromuscular Agents, Child, Preschool, Cytochrome P-450 CYP3A Inhibitors, Female, business, Azo Compounds, medicine.drug
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60d9913e9af5e9910daa01792db02396
https://www.research.manchester.ac.uk/portal/en/publications/modelbased-drugdrug-interaction-extrapolation-strategy-from-adults-to-children--risdiplam-in-pediatric-patients-with-spinal-muscular-atrophy(c85742c4-c14d-419d-9311-c599b740e7f5).html -
7
المؤلفون: Elke Zwanziger, Daniela Fraier, Julian Potter, Katja Heinig
المصدر: Bioanalysis. 12(21)
مصطلحات موضوعية: Bioanalysis, business.industry, Clinical Biochemistry, General Medicine, Bioinformatics, Pediatric drug, Analytical Chemistry, Medical Laboratory Technology, Drug Development, Medicine, Humans, General Pharmacology, Toxicology and Pharmaceutics, business, Child, Protein Binding
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8
المؤلفون: Luca Ferrari, Daniela Fraier, Katja Heinig, Elke Zwanziger
المصدر: Bioanalysis. 11(18)
مصطلحات موضوعية: Bioanalysis, Clinical Biochemistry, General Medicine, Root cause, Reference Standards, Method development, Analytical Chemistry, Medical Laboratory Technology, Metabolism, Tandem Mass Spectrometry, Statistics, Lc ms ms, Calibration, Humans, General Pharmacology, Toxicology and Pharmaceutics, Reliability (statistics), Mathematics, Chromatography, Liquid
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9
المؤلفون: Katja Heinig, Julian Potter, Daniela Fraier, Enric Bertran
المصدر: Bioanalysis. 9:1997-2014
مصطلحات موضوعية: Bioanalysis, Clinical Biochemistry, Eye, 01 natural sciences, Specimen Handling, Analytical Chemistry, Cornea, 03 medical and health sciences, 0302 clinical medicine, Tandem Mass Spectrometry, Animals, Humans, Medicine, Pharmacokinetics, General Pharmacology, Toxicology and Pharmaceutics, Chromatography, High Pressure Liquid, Ophthalmologic drugs, business.industry, 010401 analytical chemistry, Data interpretation, General Medicine, 0104 chemical sciences, Review article, Medical Laboratory Technology, Pharmaceutical Preparations, Tears, 030221 ophthalmology & optometry, Engineering ethics, Sample collection, business, Target organ
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10
المؤلفون: Tomonori Kamei, Li Yu, Surendra Bansal, Elena Guerini, Katja Heinig, Kazuhiro Miya, Peter N. Morcos, Daniela Fraier
المصدر: Bioanalysis. 8:1465-1479
مصطلحات موضوعية: Alectinib, Bioanalysis, Lung Neoplasms, Metabolite, Clinical Biochemistry, Carbazoles, Pharmacology, 01 natural sciences, Analytical Chemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Piperidines, Limit of Detection, Tandem Mass Spectrometry, Carcinoma, Non-Small-Cell Lung, medicine, Humans, Anaplastic lymphoma kinase, Anaplastic Lymphoma Kinase, General Pharmacology, Toxicology and Pharmaceutics, Lung cancer, Protein Kinase Inhibitors, Chromatography, High Pressure Liquid, Crizotinib, Chemistry, 010401 analytical chemistry, Healthy subjects, Receptor Protein-Tyrosine Kinases, Equipment Design, General Medicine, medicine.disease, 0104 chemical sciences, Medical Laboratory Technology, Human plasma, 030220 oncology & carcinogenesis, medicine.drug