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1دورية أكاديمية
المؤلفون: Cedric O. Renaud, Panos G. Ziros, Dionysios V. Chartoumpekis, Massimo Bongiovanni, Gerasimos P. Sykiotis
المصدر: Frontiers in Endocrinology, Vol 10 (2019)
مصطلحات موضوعية: thyroid, Nrf2 (nuclear factor erythroid 2-related factor 2), Keap1 (Kelch-like ECH-associated protein 1), thyroglobulin, oxidative stress, goiter, Diseases of the endocrine glands. Clinical endocrinology, RC648-665
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Christina Thanas, Panos G. Ziros, Dionysios V. Chartoumpekis, Cédric O. Renaud, Gerasimos P. Sykiotis
المصدر: Antioxidants, Vol 9, Iss 11, p 1082 (2020)
مصطلحات موضوعية: thyroid, Nrf2 (nuclear factor erythroid 2-related factor 2), Keap1 (Kelch-like ECH-associated protein 1), thyroglobulin, oxidative stress, goiter, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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3دورية أكاديمية
المؤلفون: Federico Pio Fabrizio, Tommaso Mazza, Stefano Castellana, Angelo Sparaneo, Lucia Anna Muscarella
المصدر: Antioxidants, Vol 9, Iss 9, p 904 (2020)
مصطلحات موضوعية: KEAP1 (Kelch-like ECH-associated protein 1), methylation, NSCLC (non-small-cell lung cancer), prognostic marker, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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4دورية أكاديمية
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المؤلفون: Meidan Ying, Xuejing Shao, Hong Zhu, Ji Cao, Bo Yang, Yifan Chen, Qiaojun He
المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 309-321 (2021)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: SRC-3, nuclear receptor coactivator 3, VHL, von Hippel-Lindau tumor suppressor, RRM2, ribonucleotide reductase regulatory subunit M2, KRAS, KRAS proto-oncogene, GTPase, SNAIL1, snail family transcriptional repressor 1, medicine.medical_treatment, CRL, cullin-RING ligase, ERK, mitogen-activated protein kinase 1, NEDD8, NEDD8 ubiquitin like modifier, Review, medicine.disease_cause, JAB1, c-Jun activation domain binding protein-1, p130Cas, BCAR1 scaffold protein, Cas family member, law.invention, Targeted therapy, Degradation, 0302 clinical medicine, Ubiquitin, law, RA, retinoic acid, FBXL3, F-box and leucine rich repeat protein, Ci, cubitus interruptus, Phosphorylation, General Pharmacology, Toxicology and Pharmaceutics, Crosstalk, FBXO3/31, F-box protein 3/31, 0303 health sciences, biology, KEAP1, kelch like ECH associated protein 1, Kinase, Chemistry, KBTBD8, kelch repeat and BTB domain containing 8, CSN, COP9 signalosome, DYRK1A/B, dual-specificity tyrosine-phosphorylation-regulated kinases 1A/B, FBW7, F-box and WD repeat domain containing 7, CDT2, denticleless E3 ubiquitin protein ligase homolog, NRF2, nuclear factor, erythroid 2 like 2, TCN, triciribine hydrate, Cell biology, USP37, ubiquitin specific peptidase 37, Crosstalk (biology), XBP1, X-box binding protein 1, 030220 oncology & carcinogenesis, HCC, hepatocellular carcinomas, Vps34, phosphatidylinositol 3-kinase catalytic subunit type 3, CK1/2, casein kinase I/II, COMMD1, copper metabolism domain containing 1, KLHL3, kelch like family member 3, EMT, epithelial–mesenchymal transition, Cullin, P-TEFb, positive transcription elongation factor b, CDK2/4, cyclin dependent kinase 2/4, SPOP, speckle-type POZ protein, AIRE, autoimmune regulator, PYGO2, pygopus 2, TCOF1, treacle ribosome biogenesis factor 1, ID2, inhibitor of DNA binding 2, CHK1, checkpoint kinase 1, Kinases, FZR1, fizzy and cell division cycle 20 related 1, HIF1α, NF-κB and hypoxia inducible factor 1 subunit alpha, EXO1, exonuclease 1, ZBTB16, zinc finger and BTB domain containing 16, NOLC1, nucleolar and coiled-body phosphoprotein 1, 03 medical and health sciences, PKM2, pyruvate kinase M2 isoform, KDM2B, lysine demethylase 2B, PKC, protein kinase C, Cullin-RING ligases, medicine, BMAL1, aryl hydrocarbon receptor nuclear translocator like, ATR, ataxia telangiectasia-mutated and Rad3-related, SOCS6, suppressor of cytokine signaling 6, 030304 developmental biology, PDL1, programmed death ligand 1, HIB, Hedghog-induced MATH and BTB domain-containing protein, AKT, AKT serine/threonine kinase, lcsh:RM1-950, Ubiquitination, TRF1, telomeric repeat binding factor 1, DDB1, damage specific DNA binding protein 1, BCL2, BCL2 apoptosis regulator, CLOCK, clock circadian regulator, MYC, MYC proto-oncogene, bHLH transcription factor, lcsh:Therapeutics. Pharmacology, c-Fos, Fos proto-oncogene, AP-1 transcription factor subunit, RARα, RA receptor α, Tumorigenesis, biology.protein, Suppressor, CRY1, cryptochrome circadian regulator 1, ERG, ETS transcription factor ERG, Carcinogenesis
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المصدر: Cellular and Molecular Gastroenterology and Hepatology
مصطلحات موضوعية: Male, 0301 basic medicine, NF-E2-Related Factor 2, Cellular differentiation, Notch signaling pathway, ARE, antioxidant response element, Math1, mouse atonal homolog 1, Biology, environment and public health, digestive system, Cell Line, Mice, cDNA, complementary DNA, 03 medical and health sciences, PCR, polymerase chain reaction, 0302 clinical medicine, Intestine, Small, Basic Helix-Loop-Helix Transcription Factors, Animals, Regeneration, Intestinal Mucosa, Progenitor cell, Transcription factor, Original Research, GFP, green fluorescent protein, Signaling Crosstalk, Hepatology, Effector, Stem Cells, Gastroenterology, Progenitor Cells, Cell Differentiation, respiratory system, Intestinal epithelium, CDDO-Im, oleanolic acid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl] imidazole, mRNA, messenger RNA, Cell biology, Keap1, Kelch-like ECH-associated protein 1, Crosstalk (biology), Enterocytes, Hes1, hairy and enhancer of split-1, 030104 developmental biology, Models, Animal, Female, 030211 gastroenterology & hepatology, Intestinal Homeostasis, Signal transduction, LCM, laser capture microdissection, Nrf2, NF-E2-related factor 2
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المؤلفون: Menghao Huang, Kushan Chowdhury, Zhigang Fang, X. Charlie Dong, Ming O. Li, Suthat Liangpunsakul, Hyeong-Geug Kim
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 921-942 (2021)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: 0301 basic medicine, Sestrins, MPO, myeloperoxidase, Mitogen-Activated Protein Kinase Kinase 7, RC799-869, DMSO, dimethyl sulfoxide, FoxO, forkhead box O, Sesn1/2/3, sestrin1/2/3, medicine.disease_cause, TKO, triple knockout, Mice, PCR, polymerase chain reaction, 0302 clinical medicine, GSH, glutathione, Phosphorylation, NF-κB, nuclear factor kappa B, Original Research, Cat, catalase, Mice, Knockout, Sestrin, Gpx3, glutathione peroxidase 3, Il6, interleukin 6, WD, Western diet, biology, Chemistry, Kinase, Fatty liver, Tgfbr1, transforming growth factor beta receptor 1, Gastroenterology, Col1a1, collagen type 1 alpha 1, Nox1, NADPH oxidase 1, Diseases of the digestive system. Gastroenterology, Dgat2, diacylglycerol O-acyltransferase 2, Cell biology, Keap1, Kelch-like ECH-associated protein 1, C-Jun N-Terminal Kinase, Liver, Lipotoxicity, c-Jun N-terminal kinases, JNK, c-Jun N-terminal kinase, 030211 gastroenterology & hepatology, Disease Susceptibility, Signal transduction, NASH, nonalcoholic steatohepatitis, Gss, glutathione synthetase, Pdgfrb, platelet-derived growth factor receptor beta, Timp1, tissue inhibitor of metalloproteinase 1, Fasn, fatty acid synthase, Fatty Liver Disease, Sod, superoxide dismutase, Acta2, smooth muscle actin alpha 2, ER, endoplasmic reticulum, PA, palmitic acid, 03 medical and health sciences, 4-HNE, 4-hydroxynonenal, MKK, mitogen-activated protein kinase kinase, medicine, Animals, Humans, Srebp, sterol regulatory element-binding protein, Protein kinase A, KD, knockdown, MDA, malondialdehyde, Inflammation, KO, knockout, Hepatology, NRF2, nuclear factor erythroid 2-related like 2, JNK Mitogen-Activated Protein Kinases, Lipid Metabolism, medicine.disease, Tgfb1, transforming growth factor beta 1, WT, wild-type, mTORC, mechanistic target of rapamycin complex, Fatty Liver, AMPK, AMP-activated protein kinase, Disease Models, Animal, Oxidative Stress, Scd1, stearoyl-CoA desaturase 1, 030104 developmental biology, Gene Expression Regulation, Cytoprotection, Hepatocytes, biology.protein, BSA, bovine serum albumin, SD, standard deviation, DHE, dihydroethidium, PERK, protein kinase R-like endoplasmic reticulum kinase, Tnf, tumor necrosis factor, Biomarkers, Oxidative stress
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1574bc0f082fa7f7fd23bf88f6f9c6fc
http://www.sciencedirect.com/science/article/pii/S2352345X21000862 -
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المؤلفون: Hui Liu, Sara Maimouni, Sara Coppola, Ye Zhang, Jianliang Shen, Yijun Wang, Shenglan Gao, Ying-Tang Gao, Fengmei Wang, Heineken Queen Daguplo, Wei-Xing Zong, Junrong Yan, Zhi Du, Fang Wang, Yongbo Wang, Peng Wang, Bin Yang, Qin Zhang, Grace L. Guo, Kesong Peng, Wen-Xing Ding, Weiwei Dai, Fei Tang
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 5, Pp 1369-1385 (2021)مصطلحات موضوعية: Male, 0301 basic medicine, PCNA, proliferation cell nuclear antigen, Carcinogenesis, Apoptosis, RC799-869, DMEM, Dulbecco’s modified Eagle’s medium, TRIM21, tripartite motif-containing protein 21, Mice, PCR, polymerase chain reaction, 0302 clinical medicine, Ubiquitin, Tumor Cells, Cultured, Diethylnitrosamine, 8-oxo-dG, 8-oxo-2-deoxyguanosine, Original Research, Mice, Knockout, Kelch-Like ECH-Associated Protein 1, AFP, α-fetoprotein, biology, p62, Liver Neoplasms, Gastroenterology, RNA-Binding Proteins, Diseases of the digestive system. Gastroenterology, PBST, phosphate-buffered saline with 0.02% Tween 20, Prognosis, mRNA, messenger RNA, Ubiquitin ligase, Keap1, Kelch-like ECH-associated protein 1, Gene Expression Regulation, Neoplastic, Survival Rate, Ribonucleoproteins, Knockout mouse, 030211 gastroenterology & hepatology, IHC, immunohistochemistry, Programmed cell death, LD, ligase dead, SDS, sodium dodecyl sulfate, Carcinoma, Hepatocellular, NF-E2-Related Factor 2, PBS, phosphate-buffered saline, Oxidative phosphorylation, Nrf2, α-SMA, α-smooth muscle actin, PI, propidium iodide, cDNA, complementary DNA, 03 medical and health sciences, ROS, reactive oxygen species, Immune system, FBS, fetal bovine serum, Biomarkers, Tumor, Animals, Humans, Carcinogen, Cell Proliferation, KO, knockout, Hepatology, Nrf2, nuclear factor E2-related factor 2, RNA-seq, RNA sequencing, Hepatocellular Carcinoma, WB, western blotting, MEF, mouse embryonic fibroblast, WT, wild-type, KEAP1, Mice, Inbred C57BL, 030104 developmental biology, PB, phenobarbital, biology.protein, Cancer research, TCGA, The Cancer Genome Atlas, HCC, hepatocellular carcinoma, TRIM21, DEN, diethylnitrosamine
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المصدر: Saudi Pharmaceutical Journal, Vol 28, Iss 11, Pp 1317-1325 (2020)
Saudi Pharmaceutical Journal : SPJمصطلحات موضوعية: 0301 basic medicine, Nrf2, Nuclear factor erythroid 2-related factor 2, Anti-oxidant defense, Bcl-2, B-cell lymphoma 2, MAPK, Mitogen-activated protein kinase, NOx, Total nitrate/nitrite, Pharmaceutical Science, Pharmacology, medicine.disease_cause, VCAM-1, vascular cell adhesion molecule-1, Anti-inflammatory response, chemistry.chemical_compound, 0302 clinical medicine, GGT, gamma-glutamyl transpeptidase, Kidney, NADPH oxidase, TNF-α, Tumor necrosis factor-alpha, biology, Chemistry, Keap1, Kelch-like ECH-associated protein 1, H & E, Hematoxylin and eosin, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Original Article, NADPH, Nicotinamide adenine dinucleotide phosphate, HO-1, Heme oxygenase-1, BUN, Blood urea nitrogen, medicine.drug, GGT inhibition, CMC, Carboxymethyl cellulose, NO, Nitric oxide, Nephrotoxicity, GSH, Reduced glutathione, 03 medical and health sciences, medicine, Amlodipine, IL-6, Interleukin-6, Cisplatin nephrotoxicity, MDA, Malondialdehyde, ComputingMethodologies_COMPUTERGRAPHICS, Cisplatin, lcsh:RM1-950, NF-κB, Nuclear factor-kappa B, Glutathione, HGF, Hepatocyte growth factor, Bax, Bcl-2-associated X protein, lcsh:Therapeutics. Pharmacology, 030104 developmental biology, Renal cell survival, Apoptosis, biology.protein, Oxidative stress, ROS, Reactive oxygen species
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المؤلفون: Yajie Wen, Jiahong Sun, Panpan Chen, Wenzhou Li, Tingying Jiao, Huichang Bi, Yanying Zhou, Yixin Chen, Lihuan Guan, Pan Chen, Fan Xiaomei, Yiming Jiang, Min Huang
المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 1, Pp 89-99 (2021)مصطلحات موضوعية: GSTα, glutathianone S-transferase α, NAPQI, N-acetyl p-benzoquinone imine, AST, aspartate aminotransferase, Pharmacology, medicine.disease_cause, BrdU, bromodeoxyuridine, CDK4, cyclin-dependent kinase 4, 0302 clinical medicine, AAV, adeno-associated virus, ECL, electrochemiluminescence, GSTμ, glutathione S-transferase μ, GSH, glutathione, General Pharmacology, Toxicology and Pharmaceutics, HO-1, heme oxygenase-1, Liver injury, 0303 health sciences, Gene knockdown, biology, LDH, lactate dehydrogenase, Chemistry, CYP450, cytochromes P450, digestive, oral, and skin physiology, SIRT6, sirtuin 6, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Hepatocyte, Sirtuin, NRF2, nuclear factor erythroid 2-related factor 2, KEAP1, Kelch-like ECH-associated protein 1, Original Article, SIRT6, DNA damage, APAP, acetaminophen, ARE, antioxidant response element, NRF2, ALT, serum alanine aminotransferase, 03 medical and health sciences, H3K9ac, histone H3 Nε-acetyl-lysines 9, CCK-8, cell counting kit-8, ROS, reactive oxygen species, ALF, acute liver failure, Dox, doxorubicin, H3K56ac, histone H3 Nε-acetyl-lysines 56, medicine, Viability assay, 030304 developmental biology, Acetaminophen, P53, CCND1, cyclin D1, lcsh:RM1-950, Hepatotoxicity, medicine.disease, BCA, bicinchoninic acid, lcsh:Therapeutics. Pharmacology, DCF, dichlorofluorescein, siRNA, small interfering RNA, biology.protein, H&E, hematoxylin and eosin, CCNA1, cyclin A1, NQO1, NAD(P)H quinone dehydrogenase 1, Co-IP, co-immunoprecipitation, Oxidative stress