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المؤلفون: Qiang Yu, Dave S.B. Hoon, Diego Marzese, Hao Zhang, Yufeng Chen, Yu Cai, Puay Leng Lee, Yi Bao, Min Feng, Keng Gat Lim, Wenyu Wang
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::428de6c720a4a82de98b66e12c0a7e62
https://doi.org/10.1158/1535-7163.22505097.v1 -
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المؤلفون: Qiang Yu, Dave S.B. Hoon, Diego Marzese, Hao Zhang, Yufeng Chen, Yu Cai, Puay Leng Lee, Yi Bao, Min Feng, Keng Gat Lim, Wenyu Wang
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::af81dc2d0d86e6c7e1bc23422fba5676
https://doi.org/10.1158/1535-7163.c.6537948.v1 -
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المؤلفون: Hao Zhang, Yufeng Chen, Diego M. Marzese, Qiang Yu, Keng Gat Lim, Puay Leng Lee, Yu Cai, Min Feng, Dave S.B. Hoon, Wenyu Wang, Yi Bao
المصدر: Molecular Cancer Therapeutics. 17:1973-1983
مصطلحات موضوعية: 0301 basic medicine, Regulation of gene expression, Cancer Research, business.industry, medicine.medical_treatment, EZH2, Cancer, medicine.disease, Targeted therapy, 03 medical and health sciences, 030104 developmental biology, Breast cancer, Oncology, medicine, Cancer research, Epigenetics, business, Protein kinase B, PI3K/AKT/mTOR pathway
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5ec9da13c86789de43f38cd3c0220c78
https://doi.org/10.1158/1535-7163.mct-17-0802 -
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المؤلفون: Louisa Balazs, Andrea Balogh, Sue-Chin Lee, Karin Emmons-Thompson, Fridtjof Thomas, C. Ryan Yates, Shannon W. McCool, Jur Strobos, Derek D. Norman, Erzsebet Szabo, Shivaputra A. Patil, Gerrald I. Byrne, Alyssa Boler, Keng Gat Lim, Yuko Fujiwara, Renukadevi Patil, Gabor Tigyi, James I. Fells, Jennifer Stabenow, Duane D. Miller
المصدر: Chemistry & Biology. 22(2):206-216
مصطلحات موضوعية: Agonist, inorganic chemicals, medicine.drug_class, Clinical Biochemistry, CD34, Apoptosis, DNA Fragmentation, Biology, Biochemistry, Article, Cell Line, Histones, Mice, chemistry.chemical_compound, Lysophosphatidic acid, Drug Discovery, medicine, Animals, Humans, Receptors, Lysophosphatidic Acid, Receptor, Molecular Biology, Mice, Knockout, Pharmacology, Caspase 8, Sulfonamides, Binding Sites, Acute Radiation Syndrome, General Medicine, Protein Structure, Tertiary, Mice, Inbred C57BL, Molecular Docking Simulation, Naphthalimides, Haematopoiesis, chemistry, Gamma Rays, Immunology, Knockout mouse, Cancer research, Molecular Medicine, Lysophospholipids
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المؤلفون: Wenyu, Wang, Keng Gat, Lim, Min, Feng, Yi, Bao, Puay Leng, Lee, Yu, Cai, Yufeng, Chen, Hao, Zhang, Diego, Marzese, Dave S B, Hoon, Qiang, Yu
المصدر: Molecular cancer therapeutics. 17(9)
مصطلحات موضوعية: Jumonji Domain-Containing Histone Demethylases, Sulfonamides, Indazoles, Cell Survival, Gene Expression Profiling, Breast Neoplasms, Kaplan-Meier Estimate, Cell Line, Epigenesis, Genetic, Gene Expression Regulation, Neoplastic, Phosphatidylinositol 3-Kinases, Drug Resistance, Neoplasm, Cell Line, Tumor, MCF-7 Cells, Humans, Enhancer of Zeste Homolog 2 Protein, Female, Insulin-Like Growth Factor Binding Protein 5, Proto-Oncogene Proteins c-akt, Phosphoinositide-3 Kinase Inhibitors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::aa5d59ea2494bf66d1b803606fdc24a6
https://pubmed.ncbi.nlm.nih.gov/29925528 -
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المؤلفون: Susan Pyne, Nigel J. Pyne, Keng Gat Lim, Alexander I. Gray
المصدر: British Journal of Pharmacology. 166:1605-1616
مصطلحات موضوعية: Pharmacology, Sphingosine, biology, Poly ADP ribose polymerase, Sphingosine kinase, Resveratrol, Ampelopsin, chemistry.chemical_compound, chemistry, Sphingosine kinase 1, Biochemistry, Cancer cell, biology.protein, Sphingosine-1-phosphate, skin and connective tissue diseases
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المؤلفون: Jaclyn S. Long, Susan Pyne, Keng Gat Lim, Joanne Edwards, Francesca Tonelli, Nigel J. Pyne
المصدر: Biochemical Society Transactions. 40:94-100
مصطلحات موضوعية: Sphingosine-1-phosphate receptor, Sphingosine kinase, Antineoplastic Agents, Biochemistry, chemistry.chemical_compound, Sphingosine, Neoplasms, Animals, Humans, Sphingosine-1-phosphate, biology, Receptor Protein-Tyrosine Kinases, Oncogenes, Lipid signaling, Cell biology, Phosphotransferases (Alcohol Group Acceptor), Receptors, Lysosphingolipid, Receptors, Estrogen, Sphingosine kinase 1, chemistry, Drug Resistance, Neoplasm, biology.protein, lipids (amino acids, peptides, and proteins), Lysophospholipids, Signal transduction, Tyrosine kinase, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21db4aafd2a3f8faa4037b1f41b1d2ec
https://doi.org/10.1042/bst20110602 -
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المؤلفون: Xuequan Lu, Susan Pyne, Zaiguo Li, Nigel J. Pyne, Francesca Tonelli, Keng Gat Lim, Robert Bittman
المصدر: Journal of Biological Chemistry. 286:18633-18640
مصطلحات موضوعية: Sphingosine, biology, Allosteric regulation, Cell Biology, Biochemistry, Sphingolipid, chemistry.chemical_compound, chemistry, Sphingosine kinase 1, Cell culture, hemic and lymphatic diseases, Fingolimod Hydrochloride, biology.protein, Enzyme kinetics, Cytoskeleton, Molecular Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::af65fd18d4307e08124cd58ba742ca3f
https://doi.org/10.1074/jbc.m111.220756 -
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المؤلفون: Stuart M. Pitson, Jaclyn S. Long, Francesca Tonelli, Evgeny V. Berdyshev, Keng Gat Lim, Tamara M. Leclercq, Carolyn Loveridge, Rothwelle J. Tate, Viswanathan Natarajan, Susan Pyne, Nigel J. Pyne
المساهمون: Loveridge, Carolyn, Tonelli, Francesca, Leclercq, Tamara, Lim, Keng Gat, Long, Jaclyn S, Berdyshev, Evgeny, Tate, Rothwelle J, Natarajan, Viswanathan, Pitson, Stuart M, Pyne, Nigel J, Pyne, Susan
المصدر: Journal of Biological Chemistry. 285:38841-38852
مصطلحات موضوعية: Male, Proteasome Endopeptidase Complex, proteasomal degradation, Ceramide, Cell Survival, Apoptosis, Breast Neoplasms, cell survival, Biochemistry, Gene Expression Regulation, Enzymologic, chemistry.chemical_compound, Cell Line, Tumor, LNCaP, Humans, mammalian cells, Molecular Biology, basal conditions, ceramides, proteasomes, sphingosine, Sphingosine, biology, Ubiquitin, apoptosis, Prostatic Neoplasms, induced apoptosis, Cell Biology, Sphingolipid, Cell biology, Gene Expression Regulation, Neoplastic, Phosphotransferases (Alcohol Group Acceptor), Thiazoles, sphingosine 1 phosphates, Proteasome, chemistry, Sphingosine kinase 1, Cell culture, prostate cancer cells, biology.protein, Female, pulmonary artery smooth muscle cells, human activities, breast cancer cells, Densitometry, Signal Transduction, bioactive lipids, LNCaP cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d2480fe7c3aaefd328c2011613162ec
https://doi.org/10.1074/jbc.m110.127993 -
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المؤلفون: Keng Gat Lim, Nahoum G. Anthony, Susan Pyne, Simon P. Mackay, Nigel J. Pyne, Alexander I. Gray
المصدر: Archives of toxicology. 88(12)
مصطلحات موضوعية: endocrine system diseases, Health, Toxicology and Mutagenesis, Apoptosis, Disease, Biology, Pharmacology, Resveratrol, Toxicology, RS, chemistry.chemical_compound, Neoplasms, Drug Discovery, Stilbenes, medicine, Animals, Humans, Sphingolipids, Binding Sites, Molecular Structure, Drug discovery, organic chemicals, food and beverages, Neurodegenerative Diseases, General Medicine, Sphingolipid, Antineoplastic Agents, Phytogenic, Molecular Docking Simulation, Mechanism of action, Biochemistry, chemistry, Cardiovascular Diseases, Sphingolipid metabolism, Toxicity, medicine.symptom, Signal transduction, Signal Transduction
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