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1دورية أكاديمية
المؤلفون: Bianca Maria Maglia Orlandi, Omar Asdrúbal Vilca Mejia, Gabrielle Barbosa Borgomoni, Maxim Goncharov, Kenji Nakahara Rocha, Lucas Bassolli, Pedro Gabriel Melo de Barros E Silva, Marcelo Arruda Nakazone, Alexandre Sousa, Valquíria Pelisser Campagnucci, Karlos Alexandre de Sousa Vilarinho, Marcelo Katz, Marcos Gradim Tiveron, Magaly Arrais Dos Santos, Luiz Augusto Ferreira Lisboa, Luis Alberto de Oliveira Dallan, Fábio Biscegli Jatene, REPLICCAR II Study Group
المصدر: PLoS ONE, Vol 15, Iss 7, p e0223343 (2020)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1932-6203
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2دورية أكاديمية
المؤلفون: Kenji Nakahara, Hiromichi Fujioka
المصدر: Symmetry, Vol 2, Iss 2, Pp 437-454 (2010)
مصطلحات موضوعية: desymmetrization, symmetric diene, chiral auxiliary, C2-symmetric diol, acetal, Mathematics, QA1-939
وصف الملف: electronic resource
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3
المؤلفون: Takuya Oguma, Shota Uehara, Kenji Nakahara, Yuya Okuyama, Kouki Fuchino, Naoyuki Suzuki, Yukiko Kan, Naoki Kanegawa, Yuki Ogata, Ken-ichi Kusakabe
المصدر: ACS Medicinal Chemistry Letters. 14:223-228
مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Biochemistry
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4
المؤلفون: Yuto Unoh, Shota Uehara, Kenji Nakahara, Haruaki Nobori, Yukiko Yamatsu, Shiho Yamamoto, Yuki Maruyama, Yoshiyuki Taoda, Koji Kasamatsu, Takahiro Suto, Kensuke Kouki, Atsufumi Nakahashi, Sho Kawashima, Takao Sanaki, Shinsuke Toba, Kentaro Uemura, Tohru Mizutare, Shigeru Ando, Michihito Sasaki, Yasuko Orba, Hirofumi Sawa, Akihiko Sato, Takafumi Sato, Teruhisa Kato, Yuki Tachibana
المصدر: Journal of Medicinal Chemistry. 65:6499-6512
مصطلحات موضوعية: Mice, COVID-19 Vaccines, SARS-CoV-2, Drug Discovery, Animals, Humans, Molecular Medicine, Protease Inhibitors, Antiviral Agents, Coronavirus 3C Proteases, COVID-19 Drug Treatment
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5
المؤلفون: Hironobu Shinoaki, Kei Tokumoto, Katsuya Mashima, Kenji Nakahara
المصدر: Journal of the Japan Society of Powder and Powder Metallurgy. 68:175-181
مصطلحات موضوعية: Materials science, Mechanical Engineering, Powder metallurgy, Metallurgy, Alloy, Materials Chemistry, Metals and Alloys, engineering, engineering.material, Microstructure, Industrial and Manufacturing Engineering, Corrosion
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a0628331b9f0a9553746d8c71844d2e6
https://doi.org/10.2497/jjspm.68.175 -
6
المؤلفون: Yasuyoshi Iso, Shigeru Ando, Harrie J.M. Gijsen, Yasuto Kido, Shinji Suzuki, Herman Borghys, Kenji Morimoto, Vijay Urmaliya, Deborah Dhuyvetter, Takahiko Yamamoto, Ard Teisman, Gaku Sakaguchi, Naoki Kanegawa, Nigel Austin, Eriko Matsuoka, An Van Den Bergh, Hisanori Ito, Takuya Oguma, Francois Paul Bischoff, Tamio Fukushima, Peter Verboven, Tomoyuki Kawachi, Kenji Nakahara, Yoshinori Yamano, Kosuke Anan, Ken-ichi Kusakabe
المصدر: ChemMedChem. 14:1894-1910
مصطلحات موضوعية: Male, Models, Molecular, hERG, Thiazines, Pharmacology, 01 natural sciences, Biochemistry, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Dogs, Oral administration, Oxazines, Drug Discovery, Hydrolase, Amyloid precursor protein, Animals, Aspartic Acid Endopeptidases, Humans, General Pharmacology, Toxicology and Pharmaceutics, Mice, Knockout, chemistry.chemical_classification, Mice, Inbred ICR, Amyloid beta-Peptides, Trifluoromethyl, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Rats, 0104 chemical sciences, Mice, Inbred C57BL, 010404 medicinal & biomolecular chemistry, Enzyme, Drug Design, Hepatocytes, Microsomes, Liver, biology.protein, Microsome, Molecular Medicine, Efflux, Amyloid Precursor Protein Secretases
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7
المؤلفون: Kenji Nakahara, Yasuto Kido, Ken-ichi Kusakabe, Satoshi Kasuya, Yasunori Mitsuoka, Takahiko Yamamoto, Shiho Yamamoto, Hisanori Ito
المصدر: European journal of medicinal chemistry. 216
مصطلحات موضوعية: Stereochemistry, Pyridines, Static Electricity, Drug Evaluation, Preclinical, chemistry.chemical_element, Crystal structure, Molecular Dynamics Simulation, Crystallography, X-Ray, 01 natural sciences, Amidine, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, Dogs, Alzheimer Disease, Microsomes, mental disorders, Drug Discovery, Pyridine, Amyloid precursor protein, Potency, Moiety, Animals, Aspartic Acid Endopeptidases, Humans, Protease Inhibitors, Naphthyridines, 030304 developmental biology, Pharmacology, chemistry.chemical_classification, 0303 health sciences, Amyloid beta-Peptides, Binding Sites, biology, 010405 organic chemistry, Organic Chemistry, General Medicine, 0104 chemical sciences, Rats, Enzyme, chemistry, biology.protein, Fluorine, Amyloid Precursor Protein Secretases, Half-Life
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8
المؤلفون: Yasuyoshi Iso, Naoki Kanegawa, Vijay Urmaliya, Kazuki Fujimoto, Kazuo Komano, Ard Teisman, An Van Den Bergh, Herman Borghys, Hisanori Ito, Shuhei Yoshida, Shigeru Ando, Yasuto Kido, Nigel E. Austin, Naoya Asada, Shinji Suzuki, Kenji Nakahara, Ken-ichi Kusakabe, Eriko Matsuoka, Harrie J.M. Gijsen, Gaku Sakaguchi, Genta Tadano, Yoshinori Yamano, Tamio Fukushima, Takahiko Yamamoto, Deborah Dhuyvetter, Kouki Fuchino
المصدر: Journal of medicinal chemistry. 62(20)
مصطلحات موضوعية: Male, Liver toxicity, Drug Evaluation, Preclinical, Thiazines, Pharmacology, 01 natural sciences, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Mice, Dogs, In vivo, Thiazine, Alzheimer Disease, mental disorders, Drug Discovery, Amyloid precursor protein, Animals, Humans, Protease Inhibitors, Volume concentration, 030304 developmental biology, Cytochrome P-450 CYP2C9, 0303 health sciences, Amyloid beta-Peptides, biology, Half-life, Brain, Heart, Haplorhini, 0104 chemical sciences, Rats, 010404 medicinal & biomolecular chemistry, chemistry, Liver, biology.protein, β secretase, Molecular Medicine, Trough level, Female, Amyloid Precursor Protein Secretases, Half-Life
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9
المؤلفون: Bianca Maria Maglia Orlandi, Kenji Nakahara Rocha, Fabio B. Jatene, Luís A. P. Dallan, Maxim Goncharov, Luiz A. Lisboa, Omar Asdrubal VilcaMejia, Lucas Bassolli
مصطلحات موضوعية: Continuous variable, medicine.medical_specialty, Data collection, business.industry, Data quality, Quality Score, medicine, Aggregate data, Audit, Data entry, business, Categorical variable, Surgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ce8048603adb10810113c6a2f2745e
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المؤلفون: Takahiko Yamamoto, Yasuyoshi Iso, Harrie J.M. Gijsen, Tsuyoshi Hasegawa, Tamio Fukushima, Hisanori Ito, Yoshinori Yamano, Ken-ichi Kusakabe, Yasuto Kido, Herman Borghys, Motoko Hosono, Kenji Nakahara, Kouki Fuchino, Yusuke Sako, Shigeru Ando, Naoya Asada, Kazuo Komano, Gaku Sakaguchi, Masayoshi Ogawa, Genta Tadano, Chie Unemura, Deborah Dhuyvetter, Shuichi Ohnishi
المصدر: Journal of Medicinal Chemistry. 61:5525-5546
مصطلحات موضوعية: 0301 basic medicine, Pyrazine, Protein Conformation, Stereochemistry, hERG, 01 natural sciences, Rats, Sprague-Dawley, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Protein structure, In vivo, Oxazines, Drug Discovery, Animals, Humans, Structure–activity relationship, Potency, Tissue Distribution, Enzyme Inhibitors, Dose-Response Relationship, Drug, biology, 010405 organic chemistry, Drug discovery, Brain, Rats, 0104 chemical sciences, Molecular Docking Simulation, 030104 developmental biology, chemistry, biology.protein, Molecular Medicine, Efflux, Amyloid Precursor Protein Secretases