نتائج البحث - "Keratins genetics"

1

A human keratin 10 knockout causes recessive epidermolytic hyperkeratosis

المؤلفون: Daniel Hohl, Ingrid Hausser, Felix B. Müller, Tamar Kinaciyan, Christina Schaffrath, Bernhard P. Korge, Meral J. Arin, Thomas Krieg, Marcel Huber

المصدر: Human Molecular Genetics, vol. 15, no. 7, pp. 1133-41

مصطلحات موضوعية: Male, Genotype, Hyperkeratosis, Nonsense mutation, Fluorescent Antibody Technique, Genes, Recessive, Biology, medicine.disease_cause, Epidermolytic hyperkeratosis, Models, Biological, Mice, Keratin, Genetics, medicine, Animals, Humans, RNA, Messenger, Child, Molecular Biology, Genetics (clinical), Cells, Cultured, Skin, chemistry.chemical_classification, Mutation, Hyperkeratosis, Epidermolytic, integumentary system, Homozygote, Heterozygote advantage, General Medicine, 3T3 Cells, Exons, Fibroblasts, Keratin-10, medicine.disease, Null allele, Pedigree, Microscopy, Electron, medicine.anatomical_structure, Phenotype, chemistry, Epidermal Cells, Codon, Nonsense, 3T3 Cells/cytology/metabolism Cells, Cultured Child Codon, Nonsense Epidermis/cytology/metabolism/ultrastructure Exons/genetics Female Fibroblasts/cytology/metabolism Fluorescent Antibody Technique *Genes, Recessive Genotype Homozygote Humans Hyperkeratosis, Epidermolytic/*genetics/metabolism/pathology Keratin-10 Keratins/*genetics/metabolism Male Mice Microscopy, Electron Models, Biological Pedigree Phenotype RNA, Messenger/genetics Skin/metabolism, Keratins, Female, Epidermis, Keratinocyte

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb3e82acaab0cfc7535e8979d7947b8
http://doc.rero.ch/record/303320/files/ddl028.pdf

2

p53 Is a Direct Transcriptional Repressor of Keratin 17: Lessons from a Rat Model of Radiation Dermatitis

المؤلفون: Zhicao Yue, Benhua Xu, Yuval Ramot, Xiaobo Li, Guojiang Xie, Chunyan Liao, Xi Chen, Haijie Lu, Liyan Zhu, Ralf Paus

المصدر: Liao, C, Xie, G, Zhu, L, Chen, X, Li, X, Lu, H, Xu, B, Ramot, Y, Paus, R & Yue, Z 2016, ' p53 Is a Direct Transcriptional Repressor of Keratin 17 : Lessons from a Rat Model of Radiation Dermatitis ', The Journal of investigative dermatology, vol. 136, no. 3, pp. 680-689 . https://doi.org/10.1016/j.jid.2015.12.021

مصطلحات موضوعية: 0301 basic medicine, Polymerase Chain Reaction/methods, Radiodermatitis/genetics, Repressor, Down-Regulation, Dermatology, Keratins/genetics, Biology, Biochemistry, Keratin 17, Polymerase Chain Reaction, Sensitivity and Specificity, 03 medical and health sciences, Mice, Random Allocation, Keratin, medicine, Pachyonychia congenita, Animals, Electrophoretic mobility shift assay, Rats, Wistar, Promoter Regions, Genetic, Molecular Biology, Tumor Suppressor Protein p53/metabolism, Regulation of gene expression, chemistry.chemical_classification, Promoter, Cell Biology, medicine.disease, Molecular biology, Immunohistochemistry, Rats, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, chemistry, Gene Expression Regulation, Keratins, Radiodermatitis, Tumor Suppressor Protein p53, Chromatin immunoprecipitation, DNA Damage, Protein Binding