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المؤلفون: Khalid M. Naseem, Robert A. S. Ariëns, Rhodri King, Fraser L. Macrae, Katherine J. Kearney, Ramzi A. Ajjan, Christian Tiede, Kerrie A. Smith, Benjamin E. J. Spurgeon, Iain W. Manfield, Ramsah Cheah, Fladia Phoenix, Katie J. Simmons, Darren C. Tomlinson, Nikoletta Pechlivani, Michael J. McPherson
المصدر: Blood. 133:1233-1244
مصطلحات موضوعية: 0301 basic medicine, Excessive Bleeding, Plasmin, medicine.medical_treatment, Immunology, 030204 cardiovascular system & hematology, Pharmacology, Fibrinogen, Biochemistry, Tissue plasminogen activator, Fibrin, Thrombosis and Hemostasis, 03 medical and health sciences, 0302 clinical medicine, Fibrinolysis, medicine, Humans, Thrombus, Coagulation Disorder, biology, Chemistry, Thrombosis, Blood Proteins, Cell Biology, Hematology, medicine.disease, 030104 developmental biology, Tissue Plasminogen Activator, biology.protein, Fibrin Clot Lysis Time, medicine.drug
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe1cdd67bed90e715d998738d1ed96e6
https://doi.org/10.1182/blood-2018-06-856195 -
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المؤلفون: Richard J. Pease, Helen Philippou, Emma Hethershaw, Robert A. S. Ariëns, Muriel C. Maurer, Peter J. Grant, Penelope J. Adamson, Kerrie A. Smith, W. N. Goldsberry, Sheena E. Radford
المصدر: Journal of Thrombosis and Haemostasis
مصطلحات موضوعية: 0301 basic medicine, Circular dichroism, transglutaminases, COAGULATION, 030204 cardiovascular system & hematology, Protein Structure, Secondary, catalytic domain, Substrate Specificity, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Protein structure, Thrombin, Protein Domains, protein conformation, medicine, Humans, Cysteine, Gel electrophoresis, chemistry.chemical_classification, Fibrin, Factor XIII, biology, Chemistry, Fibrinolysis, Active site, Original Articles, enzyme activation, Hematology, Recombinant Proteins, Protein tertiary structure, Protein Structure, Tertiary, Kinetics, 030104 developmental biology, Enzyme, Biochemistry, Mutation, biology.protein, Original Article, medicine.drug
وصف الملف: application/pdf
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المؤلفون: Peter J. Grant, Colin W. G. Fishwick, May Boothby, Richard J. Pease, Craig Avery, Kerrie A. Smith, Helen M. Buckley
المصدر: European Journal of Medicinal Chemistry. 98:49-53
مصطلحات موضوعية: Models, Molecular, Pharmacology, Factor XIII, biology, Stereochemistry, Tissue transglutaminase, Organic Chemistry, Drug Evaluation, Preclinical, Epoxide, General Medicine, Glutathione, Cysteine protease, chemistry.chemical_compound, Biochemistry, chemistry, Covalent bond, Drug Discovery, biology.protein, Epoxy Compounds, Potency, Pharmacophore, Cathepsin S
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المؤلفون: Kristina F. Standeven, Laura M. Newell, Kingsley R. Simpson, Christopher L. Jackson, Kerrie A. Smith, Peter J. Grant, Richard J. Pease, Paul A. Cordell, Penelope J. Adamson
المصدر: Matrix Biology. 43:85-96
مصطلحات موضوعية: Male, Tissue transglutaminase, Connective tissue, Immunofluorescence, Cell Line, Mice, Calcification, Physiologic, Antigen, GTP-Binding Proteins, medicine, Animals, Humans, Protein Glutamine gamma Glutamyltransferase 2, Molecular Biology, Mice, Knockout, Transglutaminases, medicine.diagnostic_test, biology, Antibodies, Monoclonal, Molecular biology, Transaldolase, Staining, medicine.anatomical_structure, Cell culture, biology.protein, Immunohistochemistry, Female, Antibody, Factor XIIIa
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المؤلفون: Keith Rogers, Kerrie L. Smith, Simon X. Godber, Anthony Dicken, Danae Prokopiou, Priscila Paula, Paul Evans
مصطلحات موضوعية: Diffraction, Physics, business.industry, Scattering, Detector, 02 engineering and technology, 021001 nanoscience & nanotechnology, 01 natural sciences, General Biochemistry, Genetics and Molecular Biology, 010309 optics, symbols.namesake, Optics, Position (vector), Encoding (memory), 0103 physical sciences, symbols, Coded aperture, 0210 nano-technology, business, Encoder, Debye
وصف الملف: application/pdf
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المصدر: Cardiovascular Diabetology
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, medicine.medical_treatment, Endocrinology, Diabetes and Metabolism, Hemorrhage, Review, 030204 cardiovascular system & hematology, Fibrinogen, Bioinformatics, Risk Assessment, Fibrin, 03 medical and health sciences, 0302 clinical medicine, Fibrinolytic Agents, Risk Factors, Internal medicine, Fibrinolysis, medicine, Diabetes Mellitus, Animals, Humans, Thrombus, biology, business.industry, Diabetes, Thrombosis, medicine.disease, Surgery, 030104 developmental biology, Coagulation, Cardiovascular Diseases, biology.protein, Platelet aggregation inhibitor, business, Cardiology and Cardiovascular Medicine, Fibrinolytic agent, Platelet Aggregation Inhibitors, medicine.drug
وصف الملف: application/pdf
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المؤلفون: Kelly Njine Mouapi, Robert A. S. Ariëns, Jacob Bell, Muriel C. Maurer, Kerrie A. Smith, Helen Philippou
المساهمون: Biochemie, RS: CARIM School for Cardiovascular Diseases, RS: CARIM - R1.01 - Blood proteins & engineering
المصدر: Blood, 127(18), 2241-2248. The American Society of Hematology
مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, Glutamine, Recombinant Fusion Proteins, Immunology, Lysine, Mutation, Missense, macromolecular substances, 030204 cardiovascular system & hematology, Biology, Fibrinogen, Biochemistry, Fibrin, Substrate Specificity, Thrombosis and Hemostasis, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Point Mutation, Amino Acid Sequence, Binding site, Nuclear Magnetic Resonance, Biomolecular, Thrombosis, Cell Biology, Hematology, Factor XIII, 030104 developmental biology, Covalent bond, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Mutagenesis, Site-Directed, biology.protein, Biophysics, Factor XIIIa, Heteronuclear single quantum coherence spectroscopy, Protein Binding, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d2c675066b3c6a9bc2acf55fff4d72c
https://cris.maastrichtuniversity.nl/en/publications/2c3acc58-fde3-49fc-81f9-c5ad676764a5 -
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المؤلفون: Helen Philippou, Kelly Njine Mouapi, Kerrie A. Smith, Robert A. S. Ariëns, Muriel C. Maurer
المصدر: Biophysical Journal. 110(3)
مصطلحات موضوعية: biology, Chemistry, Biophysics, Fibrinogen, Factor XIII, Fibrin Monomer, Fibrin, Thrombin, Coagulation, Biochemistry, medicine, biology.protein, Binding site, Heteronuclear single quantum coherence spectroscopy, medicine.drug
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المؤلفون: Joanna-Marie Howes, Riyaz Somani, Katharina Hess, Kerrie A. Smith, Richard J. Pease, Jeffrey N. Keen, Kristina F. Standeven, Ramzi A. Ajjan, Angela M. Carter, Victoria R. Richardson, Anna Shore, Verena Schroeder
المصدر: Diabetes and Vascular Disease Research. 9:216-225
مصطلحات موضوعية: Male, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Inflammation, Context (language use), Pharmacology, Fibrinogen, Fibrin, Plasma, Fibrinolysis, Internal Medicine, Humans, Medicine, biology, business.industry, Thrombosis, Complement C3, medicine.disease, In vitro, Complement Factor H, Immunology, biology.protein, Female, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Ex vivo, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a9f980cf72c8f7123ab8462481a439c
https://doi.org/10.1177/1479164111432788 -
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المؤلفون: Cora M Beckers, Kathryn J Griffin, Kingsley J Simpson, Jane M Brown, Paul A Cordell, Kerrie A Smith, Mark J Drinkhill, Mark T Kearney, Jean J Vacher, Richard J Pease, Peter J Grant
المصدر: Arteriosclerosis, Thrombosis, and Vascular Biology. 35
مصطلحات موضوعية: Cardiology and Cardiovascular Medicine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a051a0a17e0ebe72d0aa4f969fabd238
https://doi.org/10.1161/atvb.35.suppl_1.394