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1دورية أكاديمية
المؤلفون: Dominic Stadel, Silvia Cristofanon, Behnaz Ahangarian Abhari, Kurt Deshayes, Kerry Zobel, Domagoj Vucic, Klaus-Michael Debatin, Simone Fulda
المصدر: Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 12, Pp 1162-1170 (2011)
مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Bram Laukens, Claudia Jennewein, Barbara Schenk, Nele Vanlangenakker, Alexander Schier, Silvia Cristofanon, Kerry Zobel, Kurt Deshayes, Domagoj Vucic, Irmela Jeremias, Mathieu J.M. Bertrand, Peter Vandenabeele, Simone Fulda
المصدر: Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 10, Pp 971-979 (2011)
مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
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3
المؤلفون: Peng Gao, Paolo Vincetti, Fabio Maria Sabbatini, Holly J. Carlisle, Luisa Mengatto, Stéphane De Lombaert, Anna Sava, Kerry Zobel, Xinying Liu, Claudia Beato, Jessica M. Bright, Alyssa M. A. Toda, Elena Serra, Federica Budassi, Marco Migliore, Laura Caberlotto, Cristiana Griffante, Silvia Bernardi, Mingliang Zhang, Albert W. Garofalo, Daniele Andreotti
المصدر: Journal of Medicinal Chemistry. 63:14821-14839
مصطلحات موضوعية: Indazoles, Tetrazoles, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, 01 natural sciences, Small Molecule Libraries, Mice, Structure-Activity Relationship, 03 medical and health sciences, Drug Discovery, Animals, Humans, Kinase activity, Protein Kinase Inhibitors, Gene, 030304 developmental biology, 0303 health sciences, Molecular Structure, Chemistry, Kinase, Highly selective, LRRK2, High-Throughput Screening Assays, nervous system diseases, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, HEK293 Cells, Pyrimidines, Mutation, Cancer research, Molecular Medicine
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4
المؤلفون: Annika C. Russ, Ursula Botzenhardt, Simone Fulda, Hartmut Döhner, Sonja C. Lueck, Lars Bullinger, Kurt Deshayes, Konstanze Döhner, Kerry Zobel, Richard F. Schlenk, Domagoj Vucic
المصدر: Oncotarget
مصطلحات موضوعية: Male, 0301 basic medicine, Apoptosis, IAP proteins, 0302 clinical medicine, hemic and lymphatic diseases, Aged, 80 and over, Cell Death, Gene Expression Regulation, Leukemic, Cytarabine, Intracellular Signaling Peptides and Proteins, NF-kappa B, Myeloid leukemia, Middle Aged, XIAP, Leukemia, Myeloid, Acute, Treatment Outcome, Oncology, Receptors, Tumor Necrosis Factor, Type I, 030220 oncology & carcinogenesis, Female, Nucleophosmin, Research Paper, Signal Transduction, medicine.drug, Adult, gene expression profiling (GEP), Programmed cell death, Cell Survival, Biology, Inhibitor of apoptosis, Mitochondrial Proteins, Young Adult, 03 medical and health sciences, acute myeloid leukemia (AML), Cell Line, Tumor, medicine, Humans, ddc:610, Aged, Gene Expression Profiling, Cancer, smac mimetic, medicine.disease, Gene expression profiling, 030104 developmental biology, Mutation, Immunology, Cancer research, Apoptosis Regulatory Proteins
وصف الملف: application/octet-stream
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179abdf459ef49b1fc13210cc90be908
https://doi.org/10.18632/oncotarget.10390 -
5
المؤلفون: Russell A. Judge, Sha Jin, Lisa A. Hasvold, Andrew J. Souers, Guillaume Lessene, John Xue, Hans E. Purkey, Jun Chen, Chang H. Park, Sarah G. Hymowitz, Nathaniel D. Catron, Xilu Wang, Le Wang, Wayne J. Fairbrother, Brian J. Smith, Brad E. Sleebs, Erwin R. Boghaert, Kurt Deshayes, Chudi Ndubaku, Yu Xiao, Darren C. Phillips, Stephen K. Tahir, Steven W. Elmore, Michael J. Mitten, Zhi-Fu Tao, Keith G. Watson, Michael F. T. Koehler, Anatol Oleksijew, Saul H. Rosenberg, Peter Kovar, Paul Nimmer, Andrew M. Petros, Chris Tse, Morey L. Smith, Peter M. Colman, Haichao Zhang, Kerry Zobel, Joel D. Leverson, Peter E. Czabotar, John A. Flygare
المصدر: ACS Medicinal Chemistry Letters. 5:1088-1093
مصطلحات موضوعية: Navitoclax, Apoptosis Inhibitor, biology, Organic Chemistry, Cancer, Bcl-xL, Pharmacology, medicine.disease, Multiple dosing, Biochemistry, chemistry.chemical_compound, chemistry, Cell culture, Apoptosis, In vivo, Drug Discovery, biology.protein, medicine
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6
المؤلفون: Clifford Quan, Brian J. Smith, Peter E. Czabotar, Kerry Zobel, Kurt Deshayes, Anna V. Fedorova, David C.S. Huang, Toru Okamoto, Hong Yang, Wayne J. Fairbrother
المصدر: ACS Chemical Biology. 8:297-302
مصطلحات موضوعية: chemistry.chemical_classification, Cell, Peptide, Biological activity, General Medicine, Biology, Biochemistry, medicine.anatomical_structure, Protein structure, chemistry, Apoptosis, Intramolecular force, Helix, Biophysics, medicine, Molecular Medicine, Stapled peptide
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7
المؤلفون: Kerry Zobel, Heidi J.A. Wallweber, Anna V. Fedorova, Domagoj Vucic, Allyn J. Schoeffler, Kurt Deshayes, J. Michael Elliott, Anthony M. Giannetti, Erin C. Dueber, Brigitte Maurer, Ping Wu, Andreas Lingel, Sarah G. Hymowitz, Eugene Varfolomeev, Wayne J. Fairbrother
المصدر: Science. 334:376-380
مصطلحات موضوعية: Models, Molecular, Proteasome Endopeptidase Complex, Programmed cell death, Conformational change, Protein Conformation, Ubiquitin-Protein Ligases, Molecular Sequence Data, Inhibitor of apoptosis, Models, Biological, Protein Structure, Secondary, Cell Line, Inhibitor of Apoptosis Proteins, Mice, Protein structure, Ubiquitin, Cell Line, Tumor, Scattering, Small Angle, Animals, Humans, Protein Interaction Domains and Motifs, Amino Acid Sequence, Cloning, Molecular, Inhibitor of apoptosis domain, Multidisciplinary, biology, Ubiquitination, Ubiquitinated Proteins, Cell biology, Ubiquitin ligase, Biochemistry, Mutagenesis, Site-Directed, biology.protein, Protein Multimerization, Hydrophobic and Hydrophilic Interactions
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe4007f165a1054d8f89b198dd3388b9
https://doi.org/10.1126/science.1207862 -
8
المؤلفون: Jan Marik, Annie Ogasawara, Simon-P. Williams, Anna V. Fedorova, Alexander N. Vanderbilt, Kurt Deshayes, Christian Wiesmann, Herman Gill, Ping Wu, Judith E. Flores, Jeremy Murray, Jeff N. Tinianow, Y. Gloria Meng, Kerry Zobel
المصدر: Chemistry & Biology. 18:839-845
مصطلحات موضوعية: Phage display, Angiogenesis, Clinical Biochemistry, Peptide, Biochemistry, chemistry.chemical_compound, Text mining, Drug Discovery, medicine, Molecular Biology, Pharmacology, chemistry.chemical_classification, biology, medicine.diagnostic_test, business.industry, Cancer, General Medicine, medicine.disease, Vascular endothelial growth factor, chemistry, Positron emission tomography, Immunology, biology.protein, Cancer research, Molecular Medicine, Antibody, business
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9
المؤلفون: Andrey S. Shaw, Melinda M. Mulvihill, Domagoj Vucic, Stefanie Hedayati, Kurt Deshayes, Jason DeVoss, Donald S. Kirkpatrick, Kerry Zobel, Kebing Yu, Anna V. Fedorova, Tatiana Goncharov, Celine Eidenschenk, Anita Izrael-Tomasevic, Surinder Jeet, Wayne J. Fairbrother
المصدر: Molecular Cell. 69:551-565.e7
مصطلحات موضوعية: 0301 basic medicine, biology, Kinase, Cell Biology, digestive system diseases, Ubiquitin ligase, XIAP, Cell biology, RIPK2, 03 medical and health sciences, 030104 developmental biology, Protein kinase domain, Ubiquitin, NOD2, biology.protein, Kinase activity, Molecular Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::800e97d33197a148f2bae8be1e397628
https://doi.org/10.1016/j.molcel.2018.01.016 -
10
المؤلفون: Kerry Zobel, J. Michael Elliott, Harvey Wong, Domagoj Vucic, Justin Scheer, Eugene Varfolomeev, Kristina West, Avi Ashkenazi, Stephen E. Gould, Wayne J. Fairbrother, Bruno Alicke
المصدر: Journal of Biological Chemistry. 284:34553-34560
مصطلحات موضوعية: Agonist, Programmed cell death, Fas Ligand Protein, medicine.drug_class, Transplantation, Heterologous, Apoptosis, X-Linked Inhibitor of Apoptosis Protein, Inhibitor of apoptosis, Biochemistry, Receptors, Tumor Necrosis Factor, Fas ligand, Etanercept, Mice, Cell Line, Tumor, medicine, Animals, Humans, RNA, Small Interfering, Receptor, Molecular Biology, Cell Death, Tumor Necrosis Factor-alpha, Chemistry, Mechanisms of Signal Transduction, Cell Biology, Cell biology, XIAP, Receptors, TNF-Related Apoptosis-Inducing Ligand, Caspases, Immunoglobulin G, Cancer research, Tumor necrosis factor alpha, biological phenomena, cell phenomena, and immunity, BH3 Interacting Domain Death Agonist Protein, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea20faa46a6cc1da51d1524a917517e
https://doi.org/10.1074/jbc.m109.040139