المؤلفون: Delphine Bachelet, Thilo Albert, Cyprien Mbogning, Signe Hässler, Yuan Zhang, Stephan Schultze-Strasser, Yohann Repessé, Julie Rayes, Anna Pavlova, Behnaz Pezeshkpoor, Kerstin Liphardt, Julie E Davidson, Agnès Hincelin-Méry, Pierre Dönnes, Sébastien Lacroix-Desmazes, Christoph Königs, Johannes Oldenburg, Philippe Broët, ABIRISK consortium

المصدر: PLoS ONE, Vol 14, Iss 6, p e0218258 (2019)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/e167617cea974ae693edaf5a173d15e0

المؤلفون: Günter Mayer, Jens Müller, Nasim Shahidi Hamedani, Heiko Rühl, Bernd Pötzsch, Fabian Tolle, Johannes Oldenburg, Behnaz Pezeshkpoor, Kerstin Liphardt

المصدر: Nucleic Acid Therapeutics. 30:276-288

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Aptamer, Mutant, Hemorrhage, Ligands, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, Genetics, medicine, Humans, Blood Coagulation, Molecular Biology, Beneficial effects, Serine protease, Protease, biology, Chemistry, Thrombin, Anticoagulants, Aptamers, Nucleotide, Cytoprotection, G-Quadruplexes, Selective modulation, 030104 developmental biology, 030220 oncology & carcinogenesis, biology.protein, Molecular Medicine, Serine Proteases, Protein C, Protein Binding, Signal Transduction, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19acc50f15588aad13f68bb69aa4e3e
https://doi.org/10.1089/nat.2020.0844

المؤلفون: Johannes Oldenburg, Veit Hornung, Arijit Biswas, Kerstin Liphardt, Matthias Watzka, Katrin J. Czogalla, Klara Höning

المصدر: Blood Advances. 2:691-702

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Molecular Conformation, Quantitative Structure-Activity Relationship, Plasma protein binding, Molecular Dynamics Simulation, 030204 cardiovascular system & hematology, 4-Hydroxycoumarins, Isozyme, Thrombosis and Hemostasis, Inhibitory Concentration 50, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, In vivo, Vitamin K Epoxide Reductases, Humans, Binding site, chemistry.chemical_classification, Binding Sites, Base Sequence, Dose-Response Relationship, Drug, Anticoagulants, Rodenticides, Hematology, Molecular Docking Simulation, Oxidative Stress, 030104 developmental biology, Enzyme, chemistry, Biochemistry, Gene Knockdown Techniques, Mutation, Vitamin K epoxide reductase, Warfarin, VKORC1, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061db01697df28353c6a79448605eadd
https://doi.org/10.1182/bloodadvances.2017006775

المؤلفون: Katrin J. Czogalla, Veit Hornung, Kerstin Liphardt, Arijit Biswas, Matthias Watzka, Klara Höning, Johannes Oldenburg

المصدر: Nature Structural & Molecular Biology. 24:77-85

مصطلحات موضوعية: Protein Conformation, alpha-Helical, 0301 basic medicine, Vitamin, Phenylalanine, Drug Resistance, Plasma protein binding, 030204 cardiovascular system & hematology, Pharmacology, Biology, Reductase, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Structural Biology, Catalytic Domain, Vitamin K Epoxide Reductases, medicine, Humans, Binding site, Molecular Biology, Vitamin K2, HEK 293 cells, Warfarin, Vitamin K 2, Vitamin K 1, Molecular Docking Simulation, HEK293 Cells, 030104 developmental biology, chemistry, Biocatalysis, Vitamin K epoxide reductase, Oxidation-Reduction, Protein Binding, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7623221f4c051717708fafa9d0720f9
https://doi.org/10.1038/nsmb.3338

المؤلفون: Michael Caspers, Marco Kellner, Silvia Ulrich, Katrin J. Czogalla, Kerstin Liphardt, Ann-Cristin Berkemeier, Anna Pavlova, S Ghosh, Johannes Oldenburg, Behnaz Pezeshkpoor

المساهمون: University of Zurich, Oldenburg, Johannes

المصدر: Annals of hematology. 97(6)

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Vitamin K, medicine.drug_class, 2720 Hematology, 610 Medicine & health, Hemorrhage, 030204 cardiovascular system & hematology, Gene mutation, Bioinformatics, Cohort Studies, Factor IX, 03 medical and health sciences, 0302 clinical medicine, Valine, Internal medicine, Genotype, medicine, Humans, Genetic Predisposition to Disease, Protein Interaction Domains and Motifs, Genetic Association Studies, Aged, Aged, 80 and over, Hematology, Polymorphism, Genetic, business.industry, Haplotype, Warfarin, Anticoagulants, General Medicine, Vitamin K antagonist, Middle Aged, Phenotype, Recombinant Proteins, 030104 developmental biology, HEK293 Cells, Amino Acid Substitution, Tandem Repeat Sequences, Mutation, 10178 Clinic for Pneumology, business, Switzerland, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be20c882a83a83841d6255053461a34
https://pubmed.ncbi.nlm.nih.gov/29450643

المؤلفون: Johannes Oldenburg, Matthias Watzka, Jens Müller, Katrin J. Czogalla, Kerstin Liphardt, Philipp Westhofen, Michael Caspers

المصدر: Thrombosis Research. 135(5):977-983

مصطلحات موضوعية: Male, Vitamin, Vitamin K, γ-glutamyl carboxylase (GGCX), Reductase, Biological pathway, Mice, chemistry.chemical_compound, Exocrine Glands, Microsomes, Vitamin K Epoxide Reductases, Matrix gla protein, NAD(P)H Dehydrogenase (Quinone), Animals, Tissue Distribution, RNA, Messenger, chemistry.chemical_classification, biology, Vitamin K2, Brain, Membrane Proteins, Hematology, Pyruvate carboxylase, vitamin K 2,3-epoxide reductase (VKOR), Enzyme, Carbon-Carbon Ligases, Liver, chemistry, Biochemistry, vitamin K 2,3-epoxide reductase complex subunit 1-like 1 (VKORC1L1), biology.protein, NAD(P)H:quinone oxidoreductase 1 (NQO1), Female, VKORC1, vitamin K 2,3-epoxide reductase complex subunit 1 (VKORC1)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7490f34dceb46016bc074b2ad1fb526c

المؤلفون: Dagmar Meyer zu Heringdorf, Nicholas T. Ktistakis, Stuart M. Pitson, Karin Lichte, Karl Jakobs, Michael ter Braak, Kerstin Liphardt, Kerstin Danneberg, Timothy Hla

المساهمون: ter Braak, Michael, Danneberg, Kerstin, Lichte, Karin, Liphardt, Kerstin, Ktistakis, Nicholas T, Pitson, Stuart M, Hla, Timothy, Jakobs, Karl H, zu Heringdorf, Dagmar Meyer

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1791:357-370

مصطلحات موضوعية: G-protein-coupled receptor, Sphingosine-1-phosphate receptor, Sphingosine kinase, Immune receptor, receptor cross-activation, Diglycerides, Mice, Phosphoserine, Sphingosine, Gq, Phospholipase D, Animals, Humans, Protease-activated receptor, Receptor, Molecular Biology, Protein Kinase C, G protein-coupled receptor, Receptor, Muscarinic M3, G protein-coupled receptor kinase, biology, Chemistry, Cell Membrane, Cell Biology, plasma membrane translocation, Endocytosis, Cell biology, Phosphotransferases (Alcohol Group Acceptor), Protein Transport, Receptors, Lysosphingolipid, Gq alpha subunit, sphingosine kinase, sphingosine-1-phosphate, biology.protein, GTP-Binding Protein alpha Subunits, Gq-G11

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5834d52008bd7079bbc94577ee211ac2
https://doi.org/10.1016/j.bbalip.2009.01.019