المؤلفون: Kevin J. Tomaselli

المصدر: The Scientific World Journal, Vol 1, Pp 104-104 (2001)

مصطلحات موضوعية: Technology, Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1537-744X

URL الوصول: https://doaj.org/article/e8419997f4584bdc9e473e100a4665cf

المؤلفون: Kevin J. Tomaselli, Julia Herrmann, Robert O. Sayers, Joe C. Wu, Lalitha Kodandapani, Kathy G. Jahangiri, Craig D. Fisher, David T. Winn, Edward D. Robinson, Steven P. Meduna, Robert J. Ternansky, Pauline Yeo, Karen L. Valentino, Jose-Luis Diaz, Vincent J. Kalish, Steven D. Linton, Kristen Sebring, Robert A. Armstrong, Joseph F. Krebs, Niel C. Hoglen, Alfred P. Spada, Brad P. Hirakawa, Ning Chen, Brett R. Ullman, Brett Weylan Ching, Cheng-zhi Zhang, Xu Bai, Xin Gu, Kip Nalley, Long-Shiuh Chen, Patricia L. Gladstone, Jeff McQuiston, Teresa Aja, Todd Groessl, Donald S. Karanewsky, Suzanne Weeks, Lawrence C. Fritz, Patricia C. Contreras

المصدر: Journal of Medicinal Chemistry. 48:6779-6782

مصطلحات موضوعية: Adult, Biological Availability, Phases of clinical research, Apoptosis, Pharmacology, Jurkat Cells, Mice, Structure-Activity Relationship, Liver disease, Pharmacokinetics, In vivo, Drug Discovery, medicine, Animals, Humans, Aspartate Aminotransferases, Pentanoic Acids, Caspase, Liver injury, Cholestasis, Clinical Trials, Phase I as Topic, biology, Caspase 3, Chemistry, Liver Diseases, Alanine Transaminase, Hepatitis C, Chronic, medicine.disease, Caspase Inhibitors, In vitro, Rats, Liver, Biochemistry, Enzyme inhibitor, Hepatocytes, biology.protein, Molecular Medicine, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc05f6b9f812322c1ff557485178cfdb
https://doi.org/10.1021/jm050307e

المؤلفون: Shinichi Kitada, Jacqueline M. O'Connor, John C. Reed, Wendt Michael D, Andrew M. Petros, Alexander R. Shoemaker, Anatol Oleksijew, David J. Augeri, Craig B. Thompson, Kunzer Aaron R, Jürgen Dinges, Thomas L. Deckwerth, Stanley J. Korsmeyer, Saul H. Rosenberg, Stephen K. Tahir, Barbara A. Belli, Paul Nimmer, Baole Wang, Shi Chung Ng, Steven W. Elmore, Anthony Letai, Wang Shen, Haichao Zhang, Tilman Oltersdorf, Stephen W. Fesik, Milan Bruncko, David G. Nettesheim, Robert C. Armstrong, Michael J. Mitten, Kevin J. Tomaselli, Mary K. Joseph, Philip J. Hajduk, Chi Li

المصدر: Nature. 435:677-681

مصطلحات موضوعية: Models, Molecular, Programmed cell death, Magnetic Resonance Spectroscopy, BH3 Mimetic ABT-737, Lymphoma, Paclitaxel, Antineoplastic Agents, Apoptosis, Piperazines, Nitrophenols, Mice, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Cell Line, Tumor, Neoplasms, Animals, Humans, Carcinoma, Small Cell, Sulfonamides, Multidisciplinary, Chemistry, Biphenyl Compounds, Bcl-2 family, Cytochromes c, Drug Synergism, Cell cycle, Mitochondria, Survival Rate, Disease Models, Animal, Proto-Oncogene Proteins c-bcl-2, Biochemistry, Cancer research, Bcl-2 Homologous Antagonist-Killer Protein, Obatoclax

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70b74abfc25cb335eb6b7ab85bcb7eb8
https://doi.org/10.1038/nature03579

المؤلفون: Robert Smidt, Silvio Roggo, Julia Herrmann, Edward D. Robinson, Kathy G. Jahangiri, Teresa Aja, Kip Nalley, Thomas L. Deckwerth, Giorgio Rovelli, Kevin J. Tomaselli, Joe C. Wu, Bastian Hengerer, Steven P. Meduna, André Sauter, Jose-Luis Diaz, Joerg Kallen, Albert Schmitz, Donald S. Karanewsky, Brett R. Ullman, Steven D. Linton, Christoph Wiessner, Robert J. Ternansky, Peter R. Allegrini, Robert O. Sayers

المصدر: Bioorganic & Medicinal Chemistry Letters. 14:2685-2691

مصطلحات موضوعية: Peptidomimetic, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Oxamyl, Apoptosis, Peptide, Biochemistry, Cell Line, Inhibitory Concentration 50, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Humans, Structure–activity relationship, Molecular Biology, Caspase, chemistry.chemical_classification, Dipeptide, biology, Organic Chemistry, Neurodegenerative Diseases, Dipeptides, Caspase Inhibitors, In vitro, Stroke, Kinetics, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Carbamates

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb680f6d4dacf778afb32ec56f318e3
https://doi.org/10.1016/j.bmcl.2003.12.106

المؤلفون: Edward D. Robinson, Silvio Roggo, Joe C. Wu, Robert J. Ternansky, Jose-Luis Diaz, Teresa Aja, Kevin J. Tomaselli, Steven P. Meduna, Vincent J. Kalish, Donald S. Karanewsky, Robert O. Sayers, Albert Schmitz, Brett R. Ullman, Julia Herrmann, Kip Nalley, Thomas L. Deckwerth

المصدر: Bioorganic & Medicinal Chemistry Letters. 13:3623-3626

مصطلحات موضوعية: chemistry.chemical_classification, Programmed cell death, biology, Chemistry, Organic Chemistry, Clinical Biochemistry, Leaving group, Pharmaceutical Science, Inflammation, Cysteine Proteinase Inhibitors, Caspase Inhibitors, Biochemistry, In vitro, Structure-Activity Relationship, Enzyme, Enzyme inhibitor, Drug Discovery, biology.protein, medicine, Molecular Medicine, Structure–activity relationship, medicine.symptom, Molecular Biology, Caspase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681ec055be84e31c81b8947185e1442d
https://doi.org/10.1016/s0960-894x(03)00755-8

المؤلفون: Vanessa S. Marsden, Liam O'Connor, Lorraine A. O'Reilly, John Silke, Donald Metcalf, Paul G. Ekert, David C. S. Huang, Francesco Cecconi, Keisuke Kuida, Kevin J. Tomaselli, Sophie Roy, Don

المصدر: Nature, Nature. 419(6907):634-637

الإتاحة: https://ideas.repec.org/a/nat/nature/v419y2002i6907d10.1038_nature01101.html

المؤلفون: Teresa Aja, André Sauter, Donald S. Karanewsky, Markus Rudin, Rachel May, Peter R. Allegrini, Bastian Hengerer, Robert O. Sayers, Christoph Wiessner, Steve Linton, Albert Schmitz, Giorgio Rovelli, Kevin J. Tomaselli, Patricia C. Contreras, Joe C. Wu, Silvio Roggo, Kip Nalley, Lisa M. Adams, Thomas L. Deckwerth

المصدر: Drug Development Research. 52:579-586

مصطلحات موضوعية: biology, business.industry, Central nervous system, Ischemia, Caspase 3, Pharmacology, medicine.disease, Neuroprotection, medicine.anatomical_structure, Apoptosis, Anesthesia, medicine.artery, Drug Discovery, Middle cerebral artery, medicine, biology.protein, Artery occlusion, business, Caspase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fa9ad16436d7f28cc9622c6484c77710
https://doi.org/10.1002/ddr.1161

المؤلفون: Anu Srinivasan, Lawrence C. Fritz, Joseph F. Krebs, Kevin J. Tomaselli, Joe C. Wu, Angela M. Wong

المصدر: Biochemistry. 39:16056-16063

مصطلحات موضوعية: Octoxynol, Detergents, Molecular Sequence Data, Caspase 3, Biochemistry, Chromatography, Affinity, Substrate Specificity, law.invention, Mice, Glucosides, Affinity chromatography, Coumarins, law, Zymogen, Animals, Humans, Amino Acid Sequence, Lymphocytes, Binding selectivity, Caspase, Cell Line, Transformed, chemistry.chemical_classification, Enzyme Precursors, biology, Hydrolysis, Caspase 1, Cell Membrane, Membrane Proteins, Caspase Inhibitors, Molecular biology, Amino acid, Enzyme Activation, Kinetics, Membrane, chemistry, Caspases, biology.protein, Recombinant DNA, Oligopeptides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85377f4820bad7c3fe9b3101fb133326
https://doi.org/10.1021/bi001007w

المؤلفون: Nancy A. Thornberry, Michael A. Moskowitz, Hideaki Hara, Shin Jung Kang, Anu Srinivasan, Kevin J. Tomaselli, Sepideh Amin-Hanjani, Junying Yuan, Zhihong Huang, Erin P. Peterson, Shobu Namura, Suyue Wang

المصدر: The Journal of Cell Biology

مصطلحات موضوعية: caspase-11, middle cerebral artery occlusion, medicine.medical_treatment, Caspase 1, Apoptosis, Caspase 3, Caspase-11, Brain Ischemia, Cell Line, Substrate Specificity, Mice, Enzyme activator, medicine, Animals, Combinatorial Chemistry Techniques, Protein Precursors, Caspase, Mice, Knockout, biology, Activator (genetics), Cell Biology, stroke, Caspase Inhibitors, Immunohistochemistry, Molecular biology, Caspases, Initiator, Recombinant Proteins, Cell biology, Enzyme Activation, Disease Models, Animal, Kinetics, Cytokine, Caspases, biology.protein, Cytokines, Original Article, initiator caspase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a502d00db3b7142a640f74e1c126e9
https://doi.org/10.1083/jcb.149.3.613

المؤلفون: Christian Leist, Kim Hoang, Anu Srinivasan, Donald S. Karanewsky, Tam Vu, Lawrence C. Fritz, Robert C. Armstrong, Joe C. Wu, Bryan Pham, Teresa Aja, Rob Sayers, Albert Schmitz, Angela M. Wong, Joseph F. Krebs, Aileen Aboy, Kevin J. Tomaselli

المصدر: The Journal of Cell Biology

مصطلحات موضوعية: caspase, Cytochrome c Group, Caspase 3, Cell Line, Coumarins, Zymogen, Humans, Bcl-2, programmed cell death, Caspase, Enzyme Precursors, biology, Hydrolysis, Cytochrome c, apoptosis, Membrane Proteins, Cell Biology, Caspase Inhibitors, Cell biology, Enzyme Activation, Cytosol, cytochrome c, Membrane, Proto-Oncogene Proteins c-bcl-2, Cytoplasm, Caspases, biology.protein, Oligopeptides, Intracellular, Subcellular Fractions, Regular Articles

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::789f6e636e676d741d6d8f50362f45a9
https://doi.org/10.1083/jcb.144.5.915