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المؤلفون: Kevin W. Tipping, Thembaninkosi G. Gaule, Keri M. Fishwick, Amy L. Turner, Anna A Tang, Britta Petersen, Heather L. Martin, Sophie E. Saunders, Chi H. Trinh, Darren C. Tomlinson, Ajinkya Rao, Alexander L. Breeze, Matthew D. Johnson, Thomas A. Edwards, Thomas L. Adams, Maia Harvey, Katarzyna Z. Haza, Thomas Taylor, Michael J. McPherson, Modupe Ajayi, Christian Tiede
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
'Nature Communications ', vol: 12, pages: 4045-1-4045-15 (2021)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, Gene isoform, Cancer therapy, Affimer, Science, Allosteric regulation, Mutant, Druggability, General Physics and Astronomy, Computational biology, Article, General Biochemistry, Genetics and Molecular Biology, Recombinant protein therapy, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, Drug Discovery, Humans, X-ray crystallography, Biological Products, Multidisciplinary, Chemistry, Oncogenes, General Chemistry, 030104 developmental biology, ras Proteins, Pharmacophore, Cell Surface Display Techniques, Allosteric Site, 030217 neurology & neurosurgery, Signal Transduction
وصف الملف: application/pdf
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2دورية أكاديمية
المؤلفون: Sophia C Goodchild, Tania Sheynis, Rebecca Thompson, Kevin W Tipping, Wei-Feng Xue, Neil A Ranson, Paul A Beales, Eric W Hewitt, Sheena E Radford
المصدر: PLoS ONE, Vol 9, Iss 8, p e104492 (2014)
وصف الملف: electronic resource
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المؤلفون: Katarzyna Z. Haza, Kevin W. Tipping, Heather L. Martin, Anna A Tang, Ajinkya Rao, Michael J. McPherson, Modupe Ajayi, Thembaninkosi G. Gaule, Thomas Taylor, Darren C. Tomlinson, Britta Petersen, Thomas A. Edwards, Sophie E. Saunders, Keri M. Fishwick, Christian Tiede, Chi H. Trinh, Matthew D. Johnson, Amy L. Turner, Thomas L. Adams, Alexander L. Breeze
مصطلحات موضوعية: Gene isoform, chemistry.chemical_classification, Affimer, Chemistry, Mutant, Allosteric regulation, Druggability, Nucleotide, Computational biology, Pharmacophore, Signalling pathways
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dc35d330c787444b30d5ecf8446357fc
https://doi.org/10.1101/2020.06.04.133728 -
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المؤلفون: Holly Foster, Rachel Trowbridge, Alexander L. Breeze, Katarzyna Z. Haza, Kevin W. Tipping, Richard Foster, Thomas A. Edwards, Heather L. Martin, Michael J. McPherson, Darren C. Tomlinson, Christian Tiede, Chi Trinh
المصدر: Molecular Cancer Research. 18:B24-B24
مصطلحات موضوعية: Antibody mimetic, Scaffold protein, Cancer Research, Affimer, Chemistry, Effector, GTPase, medicine.disease_cause, DNA-binding protein, Small molecule, Oncology, Cancer research, medicine, KRAS, Molecular Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2ef1ea7ab65b882fb43ac7191e63b6bf
https://doi.org/10.1158/1557-3125.ras18-b24 -
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المؤلفون: Kevin W. Tipping, Theodoros K. Karamanos, Toral Jakhria, Roman Tuma, Eric W. Hewitt, Matthew G. Iadanza, Sheena E. Radford, Sophia C. Goodchild, Neil A. Ranson
المصدر: Proceedings of the National Academy of Sciences. 112:5691-5696
مصطلحات موضوعية: Amyloid, macromolecular substances, Endosomes, Protein aggregation, 010402 general chemistry, Fibril, 01 natural sciences, Monocytes, 03 medical and health sciences, Amyloid disease, chemistry.chemical_compound, medicine, Amyloid precursor protein, Humans, HSP70 Heat-Shock Proteins, Benzothiazoles, 030304 developmental biology, 0303 health sciences, Multidisciplinary, biology, Amyloidosis, Biological Sciences, Hydrogen-Ion Concentration, medicine.disease, Recombinant Proteins, 0104 chemical sciences, Biochemistry of Alzheimer's disease, Kinetics, Thiazoles, Spectrometry, Fluorescence, Membrane, Biochemistry, chemistry, biology.protein, Biophysics, Muramidase, Thioflavin, Lysosomes, beta 2-Microglobulin, Protein Binding
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb2fb710b7bbafac2bd10d2e5ae65c5
https://doi.org/10.1073/pnas.1423174112 -
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المؤلفون: Toral, Jakhria, Andrew L, Hellewell, Morwenna Y, Porter, Matthew P, Jackson, Kevin W, Tipping, Wei-Feng, Xue, Sheena E, Radford, Eric W, Hewitt
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Amyloid, Cell Survival, Membrane Proteins, Molecular Bases of Disease, macromolecular substances, Intracellular Membranes, Lysosome, Permeability, Protein Transport, Membrane Trafficking, Cell Line, Tumor, Protein Degradation, mental disorders, Proteolysis, Humans, Nanoparticles, Lysosomes, beta 2-Microglobulin, Oxidation-Reduction, Fibril
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::90d4e33fd4dc195704cc8ceadf9d5f17
https://pubmed.ncbi.nlm.nih.gov/25378395 -
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المؤلفون: Eric W. Hewitt, Andrew L. Hellewell, Wei-Feng Xue, Tania Sheynis, Anat Friediger, Kevin W. Tipping, Sheena E. Radford, Raz Jelinek
المصدر: Biophysical Journal. (3):745-755
مصطلحات موضوعية: Amyloid, Biophysics, Plasma protein binding, Epigallocatechin gallate, Fibril, Catechin, Polymerization, Cell membrane, 03 medical and health sciences, Amyloid disease, chemistry.chemical_compound, 0302 clinical medicine, medicine, Humans, QD, QC, Unilamellar Liposomes, 030304 developmental biology, 0303 health sciences, Heparin, Cell Membrane, Polyphenols, Cell biology, medicine.anatomical_structure, Membrane, Biochemistry, chemistry, Protein folding, QP517, Proteins and Nucleic Acids, beta 2-Microglobulin, 030217 neurology & neurosurgery, Protein Binding
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e69c1037e82aaaefd79431f1ab1cb16b
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