المؤلفون: Jm, Palacios, Mengod G, Mt, Vilaró, Kh, Wiederhold, Boddeke H, F. Javier Alvarez, Chinaglia G, Probst A

المصدر: Europe PubMed Central

مصطلحات موضوعية: Animals, Autoradiography, Brain, Humans, Receptors, Cholinergic, Nervous System Diseases, Receptors, Nicotinic, Tritium, Receptors, Muscarinic, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9786424d61c0dd6cbd45546e664cf80c
https://pubmed.ncbi.nlm.nih.gov/2267301

المؤلفون: Abramowski D; Novartis Institutes for Biomedical Research, CH-4056 Basel, Switzerland., Rabe S, Upadhaya AR, Reichwald J, Danner S, Staab D, Capetillo-Zarate E, Yamaguchi H, Saido TC, Wiederhold KH, Thal DR, Staufenbiel M

المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2012 Jan 25; Vol. 32 (4), pp. 1273-83.

نوع المنشور: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation*, Alzheimer Disease/*pathology , Amyloid beta-Peptides/*biosynthesis , Amyloid beta-Peptides/*genetics , Nerve Degeneration/*genetics , Neurons/*metabolism , Peptide Fragments/*biosynthesis , Peptide Fragments/*genetics, Age Factors ; Alzheimer Disease/genetics ; Alzheimer Disease/metabolism ; Animals ; Humans ; Intracellular Membranes/metabolism ; Intracellular Membranes/pathology ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Nerve Degeneration/metabolism ; Nerve Degeneration/pathology ; Neurons/pathology ; Rats

المؤلفون: Wiessner C; Novartis Institutes for Biomedical Research, CH-4056 Basel, Switzerland., Wiederhold KH, Tissot AC, Frey P, Danner S, Jacobson LH, Jennings GT, Lüönd R, Ortmann R, Reichwald J, Zurini M, Mir A, Bachmann MF, Staufenbiel M

المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2011 Jun 22; Vol. 31 (25), pp. 9323-31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease/*drug therapy , Amyloid beta-Peptides/*therapeutic use , Amyloid beta-Protein Precursor/*genetics , Amyloid beta-Protein Precursor/*immunology , Immunotherapy/*methods, Alzheimer Disease/immunology ; Amyloid beta-Peptides/adverse effects ; Animals ; Cells, Cultured ; Mice ; Mice, Transgenic ; Treatment Outcome

المؤلفون: Reichwald J; Novartis Institutes for BioMedical Research, Forum1, Novartis Campus, CH-4056 Basel, Switzerland. julia.reichwald@novartis.com, Danner S, Wiederhold KH, Staufenbiel M

المصدر: Journal of neuroinflammation [J Neuroinflammation] 2009 Nov 17; Vol. 6, pp. 35. Date of Electronic Publication: 2009 Nov 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094 (Electronic) Linking ISSN: 17422094 NLM ISO Abbreviation: J Neuroinflammation Subsets: MEDLINE

مواضيع طبية MeSH: Amyloid beta-Peptides*/genetics , Amyloid beta-Peptides*/metabolism, Aging/*physiology , Complement C1q/*metabolism , Complement C3/*metabolism , Complement C5/*metabolism , Mice, Transgenic/*metabolism, Alzheimer Disease/genetics ; Alzheimer Disease/metabolism ; Alzheimer Disease/pathology ; Animals ; Brain/metabolism ; Brain/pathology ; Complement Activation ; Complement C1q/genetics ; Complement C3/genetics ; Complement C4/genetics ; Complement C4/metabolism ; Complement C5/genetics ; Female ; Humans ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic/genetics ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism

المؤلفون: Bach P; Div of Immunology, Paul-Ehrlich-Institut, Langen, Germany., Tschäpe JA, Kopietz F, Braun G, Baade JK, Wiederhold KH, Staufenbiel M, Prinz M, Deller T, Kalinke U, Buchholz CJ, Müller UC

المصدر: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2009 Jun 15; Vol. 182 (12), pp. 7613-24.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association of Immunologists Country of Publication: United States NLM ID: 2985117R Publication Model: Print Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Amyloid beta-Peptides/*immunology , Brain/*immunology , Brain/*metabolism, Amyloid beta-Peptides/ultrastructure ; Animals ; Antibodies/immunology ; Antibody Specificity/immunology ; Brain/ultrastructure ; Cell Line ; Central Nervous System/immunology ; Female ; Humans ; Lymphocyte Activation/immunology ; Lymphocytes/immunology ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Microscopy, Immunoelectron ; Solubility ; T-Lymphocytes/immunology ; Vaccination ; Virion/ultrastructure

المؤلفون: Abramowski D; Novartis Institutes for BioMedical Research, Basel, Switzerland., Wiederhold KH, Furrer U, Jaton AL, Neuenschwander A, Runser MJ, Danner S, Reichwald J, Ammaturo D, Staab D, Stoeckli M, Rueeger H, Neumann U, Staufenbiel M

المصدر: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2008 Nov; Vol. 327 (2), pp. 411-24. Date of Electronic Publication: 2008 Aug 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0376362 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0103 (Electronic) Linking ISSN: 00223565 NLM ISO Abbreviation: J Pharmacol Exp Ther Subsets: MEDLINE

مواضيع طبية MeSH: Alanine/*analogs & derivatives , Amyloid Precursor Protein Secretases/*antagonists & inhibitors , Amyloid beta-Peptides/*metabolism , Amyloid beta-Protein Precursor/*metabolism , Azepines/*pharmacology , Brain/*metabolism , Enzyme Inhibitors/*pharmacology, Alanine/pharmacology ; Amyloid beta-Protein Precursor/analysis ; Amyloid beta-Protein Precursor/genetics ; Animals ; Half-Life ; Humans ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic

المؤلفون: Busche MA; Institut für Neurowissenschaften, Technische Universität München (TUM), 80802 München, Germany., Eichhoff G, Adelsberger H, Abramowski D, Wiederhold KH, Haass C, Staufenbiel M, Konnerth A, Garaschuk O

المصدر: Science (New York, N.Y.) [Science] 2008 Sep 19; Vol. 321 (5896), pp. 1686-9.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Disease Models, Animal*, Alzheimer Disease/*pathology , Alzheimer Disease/*physiopathology , Cerebral Cortex/*physiopathology , Neurons/*physiology , Plaque, Amyloid/*pathology , Synapses/*physiology, Amyloid beta-Peptides/metabolism ; Animals ; Calcium/metabolism ; Calcium Signaling ; Cerebral Cortex/pathology ; Maze Learning ; Memory ; Mice ; Mice, Transgenic ; Nerve Net/physiopathology ; Peptide Fragments/metabolism ; Plaque, Amyloid/chemistry

المؤلفون: Thal DR; Department of Neuropathology, University of Bonn Medical Center, Bonn, Germany. Dietmar.Thal@uni-bonn.de , Larionov S, Abramowski D, Wiederhold KH, Van Dooren T, Yamaguchi H, Haass C, Van Leuven F, Staufenbiel M, Capetillo-Zarate E

المصدر: Neurobiology of aging [Neurobiol Aging] 2007 Aug; Vol. 28 (8), pp. 1221-30. Date of Electronic Publication: 2006 Jul 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 8100437 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-1497 (Electronic) Linking ISSN: 01974580 NLM ISO Abbreviation: Neurobiol Aging Subsets: MEDLINE

مواضيع طبية MeSH: Amyloid beta-Peptides/*metabolism , Amyloid beta-Protein Precursor/*genetics , Apolipoproteins E/*metabolism , Cerebral Ventricles/*metabolism, Aging/metabolism ; Amyloid/ultrastructure ; Amyloid beta-Peptides/ultrastructure ; Animals ; Animals, Genetically Modified ; Cerebral Ventricles/anatomy & histology ; Cerebral Ventricles/ultrastructure ; Cerebrovascular Circulation ; Female ; Immunohistochemistry/methods ; Mice ; Microscopy, Electron/methods ; Models, Biological ; Mutation

المؤلفون: Stoeckli M; Novartis Institute for Biomedical Research, 4002 Basel, Switzerland., Knochenmuss R, McCombie G, Mueller D, Rohner T, Staab D, Wiederhold KH

المصدر: Methods in enzymology [Methods Enzymol] 2006; Vol. 412, pp. 94-106.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0212271 Publication Model: Print Cited Medium: Print ISSN: 0076-6879 (Print) Linking ISSN: 00766879 NLM ISO Abbreviation: Methods Enzymol Subsets: MEDLINE

مواضيع طبية MeSH: Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization*, Amyloid/*analysis, Animals ; Brain/metabolism ; Brain/pathology ; Brain Chemistry ; Mice

المؤلفون: Hintersteiner M; Discovery Technologies, Novartis Institutes for Biomedical Research, CH-4002 Basel, Switzerland., Enz A, Frey P, Jaton AL, Kinzy W, Kneuer R, Neumann U, Rudin M, Staufenbiel M, Stoeckli M, Wiederhold KH, Gremlich HU

المصدر: Nature biotechnology [Nat Biotechnol] 2005 May; Vol. 23 (5), pp. 577-83. Date of Electronic Publication: 2005 Apr 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1087-0156 (Print) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE

مواضيع طبية MeSH: Oxazines*, Alzheimer Disease/*metabolism , Alzheimer Disease/*pathology , Amyloid beta-Peptides/*metabolism , Brain/*metabolism , Brain/*pathology , Microscopy, Fluorescence/*methods , Spectrophotometry, Infrared/*methods, Amyloid beta-Peptides/ultrastructure ; Animals ; Blood-Brain Barrier/metabolism ; Disease Progression ; Female ; Fluorescent Dyes ; Mice ; Mice, Transgenic ; Tissue Distribution