المؤلفون: Ho Sing Lo, Kenrie Pui Yan Hui, Hei-Ming Lai, Xu He, Khadija Shahed Khan, Simranjeet Kaur, Junzhe Huang, Zhongqi Li, Anthony K. N. Chan, Hayley Hei-Yin Cheung, Ka-Chun Ng, John Chi Wang Ho, Yu Wai Chen, Bowen Ma, Peter Man-Hin Cheung, Donghyuk Shin, Kaidao Wang, Meng-Hsuan Lee, Barbara Selisko, Cecilia Eydoux, Jean-Claude Guillemot, Bruno Canard, Kuen-Phon Wu, Po-Huang Liang, Ivan Dikic, Zhong Zuo, Francis K. L. Chan, David S. C. Hui, Vincent C. T. Mok, Kam-Bo Wong, Chris Ka Pun Mok, Ho Ko, Wei Shen Aik, Michael Chi Wai Chan, Wai-Lung Ng

المصدر: ACS Central Science, Vol 7, Iss 5, Pp 792-802 (2021)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2374-7951

URL الوصول: https://doaj.org/article/c762182b6ed241e1a9a8500ceaadaf97

المؤلفون: Gerhard Hummer, Ivan Dikic, Donghyuk Shin, Denisa Bojkova, Gerbrand J. van der Heden van Noort, Khadija Shahed Khan, Rukmini Mukherjee, Sandra Ciesek, Hayley Hei-Yin Cheung, Paul P. Geurink, Anshu Bhattacharya, Ahmad Reza Mehdipour, Krishnaraj Rajalingam, Jindrich Cinatl, Kam-Bo Wong, Wai-Lung Ng

المساهمون: Publica

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Pharmacology, Virus Replication, Biochemistry, chemistry.chemical_compound, Chemokine CCL2, Coronavirus 3C Proteases, Research Articles, Toll-like receptor, biology, NF-kappa B, Famotidine, Molecular Docking Simulation, Cytokine release syndrome, Cytokine, medicine.symptom, Signal transduction, Histamine, medicine.drug, Protein Binding, Signal Transduction, Histamine Antagonists, Inflammation, 03 medical and health sciences, medicine, Humans, Interleukin 6, Molecular Biology, Binding Sites, 030102 biochemistry & molecular biology, business.industry, Interleukin-6, SARS-CoV-2, Cell Biology, medicine.disease, histamine, Toll-Like Receptor 3, 030104 developmental biology, chemistry, A549 Cells, SARS-CoV2, biology.protein, anti-viral signaling, Interferon Regulatory Factor-3, Caco-2 Cells, business, HeLa Cells

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee4e0ae2a6af58c43e2d7077c0f4f3f
https://doi.org/10.1016/j.jbc.2021.100925

المؤلفون: Anthony K. N. Chan, Bruno Canard, Kam-Bo Wong, John Chi Wang Ho, Po-Huang Liang, Kaidao Wang, David S.C. Hui, Kuen-Phon Wu, Junzhe Huang, Vincent Mok, Kenrie Pui Yan Hui, Barbara Selisko, Yu Wai Chen, Ho Sing Lo, Hayley Hei Yin Cheung, Khadija Shahed Khan, Cécilia Eydoux, Jean-Claude Guillemot, Chris Ka Pun Mok, Meng Hsuan Lee, Xu He, Ivan Dikic, Hei Ming Lai, Donghyuk Shin, Michael C. W. Chan, Francis K.L. Chan, Ka Chun Ng, Zhongqi Li, Wai-Lung Ng, Peter Man-Hin Cheung, Simranjeet Kaur, Bowen Ma, Wei Shen Aik, Zhong Zuo, Ho Ko

المساهمون: Aix Marseille Université (AMU), Architecture et fonction des macromolécules biologiques (AFMB), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)

المصدر: ACS Central Science
ACS Central Science, 2021, 7 (5), pp.792-802. ⟨10.1021/acscentsci.0c01186⟩
ACS Central Science, Vol 7, Iss 5, Pp 792-802 (2021)

مصطلحات موضوعية: Simeprevir, General Chemical Engineering, Hepatitis C virus, medicine.medical_treatment, [SDV]Life Sciences [q-bio], viruses, 010402 general chemistry, medicine.disease_cause, 01 natural sciences, chemistry.chemical_compound, Immune system, RNA polymerase, medicine, Protease inhibitor (pharmacology), QD1-999, ComputingMilieux_MISCELLANEOUS, Protease, 010405 organic chemistry, business.industry, virus diseases, General Chemistry, Virology, In vitro, 0104 chemical sciences, Chemistry, chemistry, business, Viral load, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e86b4cd68f7390424268d7a548eb5019
http://europepmc.org/articles/PMC8056950

المؤلفون: Khadija Shahed Khan, Fran Robson, Palma Rocchi, Wai-Lung Ng, Clément Paris, Thi Khanh Le

المساهمون: Centre de Recherche en Cancérologie de Marseille (CRCM), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Aix Marseille Université (AMU), The Chinese University of Hong Kong [Hong Kong], University of Bristol [Bristol], Rocchi, Palma, Aix Marseille Université (AMU)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC), Graduate University of Science and Technology [Hanoi] (GUST), Vietnam Academy of Science and Technology (VAST), City University of Hong Kong [Hong Kong] (CUHK)

المصدر: Trends in Biochemical Sciences
Trends in Biochemical Sciences, Elsevier, 2020, ⟨10.1016/j.tibs.2020.11.010⟩
Trends in Biochemical Sciences, 2021, 46 (5), pp.351-365. ⟨10.1016/j.tibs.2020.11.010⟩

مصطلحات موضوعية: 2019-20 coronavirus outbreak, lipid-ASO nanomicelle, MESH: CRISPR-Cas Systems, COVID-19 Vaccines, Coronavirus disease 2019 (COVID-19), [SDV]Life Sciences [q-bio], Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), viruses, Small interfering RNA (siRNA), Review, antisense oligonucleotide (ASO), Biology, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, [CHIM] Chemical Sciences, Humans, MESH: COVID-19, [CHIM]Chemical Sciences, MESH: SARS-CoV-2, RNA, Messenger, Molecular Biology, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, MESH: RNA, Messenger, 0303 health sciences, MESH: Humans, SARS-CoV-2, COVID-19, virus diseases, Virology, 3. Good health, [SDV] Life Sciences [q-bio], mRNA vaccines, MESH: COVID-19 Vaccines, 030220 oncology & carcinogenesis, siRNA, MESH: RNA, Viral, Nucleic acid, RNA-targeting CRISPR-Cas, RNA, Viral, CRISPR-Cas Systems, coronavirus (CoV)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3b9a13a7b6ef076ca178982585523a1
https://hal.archives-ouvertes.fr/hal-03117346

المؤلفون: Fran Robson, Palma Rocchi, Sinem Demirbag, Thi Khanh Le, Khadija Shahed Khan, Clément Paris, Peter Barfuss, Wai-Lung Ng

المساهمون: University of Bristol [Bristol], The Chinese University of Hong Kong [Hong Kong], Centre de Recherche en Cancérologie de Marseille (CRCM), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Aix Marseille Université (AMU), Hanoi University of Science and Technology (HUST), Sabanci University, Nanotechnology Research and Application Center, Sabanci University [Istanbul], Université Paris-Est (UPE), Aix Marseille Université (AMU)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Rocchi, Palma

المصدر: Molecular Cell
Molecular Cell, Elsevier, 2020, 79 (5), pp.710-727. ⟨10.1016/j.molcel.2020.07.027⟩
Molecular Cell, 2020, 79 (5), pp.710-727. ⟨10.1016/j.molcel.2020.07.027⟩

مصطلحات موضوعية: antisense oligonucleotide, Transcription, Genetic, MESH: Coronavirus Infections, viruses, [SDV]Life Sciences [q-bio], Cell, coronavirus, Cytidine, Viral Nonstructural Proteins, medicine.disease_cause, Virus Replication, Genome, Severity of Illness Index, 0302 clinical medicine, Transcription (biology), MESH: Molecular Targeted Therapy, MESH: COVID-19, Nucleotide, MESH: Adenosine Monophosphate, Molecular Targeted Therapy, Coronavirus, chemistry.chemical_classification, 0303 health sciences, Alanine, non-structural protein 14, virus diseases, ExoN, MESH: Amides, 3. Good health, [SDV] Life Sciences [q-bio], medicine.anatomical_structure, 030220 oncology & carcinogenesis, MESH: Pyrazines, MESH: RNA, Viral, Pyrazines, Proofreading, MESH: Betacoronavirus, RNA, Viral, MESH: Genome, Viral, Coronavirus Infections, MESH: Cytidine, medicine.drug, MESH: Antiviral Agents, MESH: Pandemics, MESH: Mutation, exonuclease, MESH: Alanine, CoV, Pneumonia, Viral, antisense oligonucleotide (ASO), Computational biology, Genome, Viral, Biology, Therapeutic targeting, Hydroxylamines, Antiviral Agents, Article, ASO, 03 medical and health sciences, Betacoronavirus, MESH: Severity of Illness Index, Coronavirus (CoV), medicine, Humans, MESH: SARS-CoV-2, anti-coronavirus drugs, Molecular Biology, Pandemics, 030304 developmental biology, Exonuclease (ExoN), MESH: Ribonucleosides, MESH: Humans, Nucleoside analogue, SARS-CoV-2, MESH: Transcription, Genetic, MESH: Virus Replication, nucleoside analog, RNA, COVID-19, Correction, MESH: Hydroxylamines, Cell Biology, Amides, Adenosine Monophosphate, non-structural protein 14 (nsp14), respiratory tract diseases, nucleoside analogue (NA), Viral replication, chemistry, MESH: Pneumonia, Viral, Mutation, nsp14, MESH: Viral Nonstructural Proteins, NA, Ribonucleosides, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e7c3d34b3a0e2ab6d0db7eece5c7f1
https://pubmed.ncbi.nlm.nih.gov/33338403

المؤلفون: Junzhe Huang, Khadija Shahed Khan, Vincent Mok, Anthony K. N. Chan, Zhong Zuo, Ho Ko, Kenrie Pui Yan Hui, Michael C. W. Chan, Kam-Bo Wong, Francis K.L. Chan, Kaidao Wang, Hei-Ming Lai, Bruno Canard, David S.C. Hui, Donghyuk Shin, Kuen-Phon Wu, Ho Sing Lo, Meng-Hsuan Lee, Po-Huang Liang, Jean-Claude Guillemot, Wai-Lung Ng, Cécilia Eydoux, Peter Man-Hin Cheung, Barbara Selisko, Ka-Chun Ng, Ivan Dikic, Yu Wai Chen, Hayley Hei-Yin Cheung, Bowen Ma, Wei Shen Aik, Simranjeet Kaur, Zhongqi Li, John Chi Wang Ho

مصطلحات موضوعية: Simeprevir, Protease, Viral protein, business.industry, viruses, Hepatitis C virus, medicine.medical_treatment, medicine.disease_cause, Virology, chemistry.chemical_compound, chemistry, Viral replication, RNA polymerase, medicine, Protease inhibitor (pharmacology), business, Viral load

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::869baad0a1ca58425a491e6cad7956a0
https://doi.org/10.1101/2020.05.26.116020