المؤلفون: Craig Davison, Roisin Morelli, Catherine Knowlson, Melanie McKechnie, Robbie Carson, Xanthi Stachtea, Kylie A. McLaughlin, Vivien E. Prise, Kienan Savage, Richard H. Wilson, Karl A. Mulligan, Peter M. Wilson, Robert D. Ladner, Melissa J. LaBonte

المصدر: npj Breast Cancer, Vol 7, Iss 1, Pp 1-13 (2021)

مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2374-4677

URL الوصول: https://doaj.org/article/d3cd97feebf847539e7f6183d26a60c8

المؤلفون: Ching-Wei Wang, Dean Fennell, Ian Paul, Kienan Savage, Peter Hamilton

المصدر: PLoS ONE, Vol 6, Iss 2, p e15818 (2011)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3046129?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/c7d89b3e8fa54c1daa4987851fc42f23

المؤلفون: Yinhai Wang, Kienan Savage, Claire Grills, Andrena McCavigan, Jacqueline A James, Dean A Fennell, Peter W Hamilton

المصدر: PLoS ONE, Vol 6, Iss 10, p e26007 (2011)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3189244?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/e73211302c6f4c78a20b3cb53ed039fd

المؤلفون: Kylie A. McLaughlin, Karl Mulligan, Xanthi Stachtea, Robbie Carson, Melanie McKechnie, Richard H. Wilson, Vivien E. Prise, Melissa J. LaBonte, Roisin Morelli, Peter M. Wilson, Kienan Savage, Robert D. Ladner, Craig Davison, Catherine Knowlson

المصدر: npj Breast Cancer, Vol 7, Iss 1, Pp 1-13 (2021)
Davison, C, Ladner, R, Morelli, R, Knowlson, C, McKechnie, M, Carson, R, McLaughlin, K, Prise, V, Stachtea, X, Savage, K, Wilson, R, Mulligan, K, Wilson, P & LaBonte Wilson, M 2021, ' Targeting nucleotide metabolism enhances the efficacy of anthracyclines and anti-metabolites in triple-negative breast cancer ', npj Breast Cancer, vol. 7, 38, pp. 3 . https://doi.org/10.1038/s41523-021-00245-5
NPJ Breast Cancer

مصطلحات موضوعية: 0301 basic medicine, DNA polymerase, DNA damage, Thymidylate synthase, Article, 03 medical and health sciences, chemistry.chemical_compound, Breast cancer, 0302 clinical medicine, SDG 3 - Good Health and Well-being, Pharmacology (medical), Radiology, Nuclear Medicine and imaging, RC254-282, Base excision repair, Deoxyuridine Triphosphate, biology, Deoxyuridine monophosphate, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Uracil, Deoxyuridine, 030104 developmental biology, Oncology, chemistry, 030220 oncology & carcinogenesis, biology.protein, Cancer research, DNA

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61cf801a8def1f526ad1626d8fea4563
https://doaj.org/article/d3cd97feebf847539e7f6183d26a60c8

المؤلفون: Stuart McIntosh, Kienan Savage, Rayhaan M.M. Ali

المصدر: Ali, R M M, McIntosh, S A & Savage, K I 2021, ' Homologous recombination deficiency in breast cancer: Implications for risk, cancer development, and therapy ', Genes Chromosomes and Cancer, vol. 60, no. 5, pp. 358-372 . https://doi.org/10.1002/gcc.22921

مصطلحات موضوعية: Genome instability, Cancer Research, DNA repair, DNA damage, Cell, homologous recombination, Breast Neoplasms, Biology, chemotherapy, Germline, 03 medical and health sciences, breast cancer, 0302 clinical medicine, Breast cancer, SDG 3 - Good Health and Well-being, Genetics, medicine, Animals, Humans, Genetic Testing, Molecular Targeted Therapy, PARP inhibitors, Germ-Line Mutation, Recombinational DNA Repair, medicine.disease, Clinical trial, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cancer research, Female, Homologous recombination

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2490b9049f8635ed7922795aa6b950d9
https://doi.org/10.1002/gcc.22921

المؤلفون: Stephen J Kirk, Gemma E Logan, Steven Walker, Tong Lioe, Stuart McIntosh, Jane Hurwitz, Paul Harkin, Colin R. James, Richard D Kennedy, Laura A. Knight, Kienan Savage, Eileen Parkes, Andrena McGavigan, Keith Lowry

المصدر: Cancer Research. 80:P1-10

مصطلحات موضوعية: Cancer Research, education.field_of_study, Cyclophosphamide, DNA repair, business.industry, Tumor-infiltrating lymphocytes, Population, medicine.disease, Immune checkpoint, Immune system, Breast cancer, Oncology, medicine, Cancer research, business, education, medicine.drug, Epirubicin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::62af8b16543f008d5cbd95d299e0e6fe
https://doi.org/10.1158/1538-7445.sabcs19-p1-10-17

المؤلفون: Kevin M. Prise, Kienan Savage, Caitríona E. McInerney, Manuel Salto-Tellez, Frank Emmert-Streib, Darragh G. McArt, Alexey Stupnikov, Stuart McIntosh, Richard D Kennedy

المساهمون: Tampere University, Computing Sciences

المصدر: Stupnikov, A, McInerney, C E, Savage, K I, McIntosh, S A, Emmert-Streib, F, Kennedy, R, Salto-Tellez, M, Prise, K M & McArt, D G 2021, ' Robustness of differential gene expression analysis of RNA-seq ', Computational and Structural Biotechnology Journal, vol. 19, pp. 3470-3481 . https://doi.org/10.1016/j.csbj.2021.05.040
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 3470-3481 (2021)

مصطلحات موضوعية: False discovery rate, Computer science, Concordance, Population, Biophysics, RNA-Seq, Computational biology, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, SDG 3 - Good Health and Well-being, Robustness (computer science), Structural Biology, Differential gene expression analysis, Linear regression, Genetics, education, Diagnostics, 030304 developmental biology, ComputingMethodologies_COMPUTERGRAPHICS, 0303 health sciences, education.field_of_study, Differential gene expression models, Precision medicine, 113 Computer and information sciences, Expression (mathematics), Computer Science Applications, Sample size determination, 030220 oncology & carcinogenesis, Standardisation, RNA-seq, TP248.13-248.65, Research Article, Biotechnology

وصف الملف: application/pdf; fulltext

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fa0eb57b0d81cfada53bb28bee42d5f
https://pure.qub.ac.uk/en/publications/e1e789db-0e5a-4081-ba4e-64282dfe53d0

المؤلفون: Ali Naqi, Joshua T. Burgess, Shu-Dong Zhang, Amila Suraweera, Nicholas W. Ashton, Emma Bolderson, Mark N. Adams, Kienan Savage, Sam Beard, Kenneth J. O'Byrne, Neha S. Gandhi, Laura V. Croft, Derek J. Richard

المصدر: Suraweera, A, Gandhi, N, Sam, B, Joshua, B, Croft, L V, Bolderson, E, Naqi, A, Ashton, N W, Adams, M, Savage, K I, Zhang, SD, O'Byrne, K J & Richard, D J 2021, ' COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks ', Communications Biology, vol. 4, 484 . https://doi.org/10.1038/s42003-021-01998-2
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)

مصطلحات موضوعية: Ubiquitylation, DNA Repair, QH301-705.5, Molecular biology, Dimer, Medicine (miscellaneous), DNA damage response, Article, General Biochemistry, Genetics and Molecular Biology, Histones, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, SDG 3 - Good Health and Well-being, Biomarkers, Tumor, Histone H2B, Humans, Monoubiquitination, DNA Breaks, Double-Stranded, Biology (General), Adaptor Proteins, Signal Transducing, 030304 developmental biology, 0303 health sciences, Mutagenesis, Chromatin, Cell biology, HEK293 Cells, chemistry, 030220 oncology & carcinogenesis, embryonic structures, Phosphorylation, General Agricultural and Biological Sciences, Homologous recombination, DNA, HeLa Cells

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc8de6332a28c66c61f1515309a818d
https://pure.qub.ac.uk/en/publications/commd4-functions-with-the-histone-h2ah2b-dimer-for-the-timely-repair-of-dna-doublestrand-breaks(ac1213b5-e01c-45fb-9109-9ed001f71c24).html

المؤلفون: David Waugh, Alan Gilmore, Simon S. McDade, Kienan Savage, Matthew Alderdice, Mark Lawler, Philip D Dunne, Darragh G. McArt, Paul G. O’Reilly, Aideen C. Roddy

المساهمون: Gilmore, Alan R, Alderdice, Matthew, Savage, Kienan, I, O Reilly, Paul G, Roddy, Aideen C, Dunne, Philip D, Lawler, Mark, McDade, Simon S, Waugh, David J, McArt, Darragh G

المصدر: Cancer Research. 79:2072-2075

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Computer science, Association (object-oriented programming), Genomic data, Big data, Evolutionary algorithm, MEDLINE, Breast Neoplasms, Computational biology, Cohort Studies, Evolution, Molecular, User-Computer Interface, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Biomarkers, Tumor, medicine, Humans, Biomarker discovery, business.industry, Genomics, medicine.disease, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Workbench, Female, Transcriptome, business, Algorithms, Software

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6aa88dc637f99af80e6ba8752fbef87
https://doi.org/10.1158/0008-5472.can-18-1976

المؤلفون: A Ervine, D Gonzalez de Castro, C Boyd, I Cameron, T Harita, Colin McIlmunn, Deirdre Fitzpatrick, Finian Bannon, Stuart McIntosh, Jacqueline James, Kienan Savage

المصدر: Cancer Research. 79:P1-09

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, business.industry, Incidence (epidemiology), Cancer, Gene mutation, medicine.disease, Cancer registry, Surgery, Breast cancer, Contralateral Prophylactic Mastectomy, Oncology, parasitic diseases, Cohort, medicine, Family history, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d4850886a864d19cc23f0a6b6d725af5
https://doi.org/10.1158/1538-7445.sabcs18-p1-09-10