المؤلفون: Liming Mao, Atika Dhar, Guangxun Meng, Ivan Fuss, Kim Montgomery-Recht, Zhiqiong Yang, Qiuyun Xu, Atsushi Kitani, Warren Strober

المصدر: Frontiers in Immunology, Vol 13 (2022)

مصطلحات موضوعية: Blau, Nod2, IRF4, NFkapapB, Crohns disease, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.988862/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/5b47c420c24a4ec0821c1dbd820857bd

المؤلفون: Atsushi Kitani, Liming Mao, Kim Montgomery-Recht, Wenchang Zhou, Adrian Wiestner, Ivan J. Fuss, Eitaro Hiejima, Warren Strober

المصدر: J Clin Invest

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Adolescent, Inflammasomes, Interleukin-1beta, Pyrin domain, Inflammatory bowel disease, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Crohn Disease, Agammaglobulinemia, immune system diseases, hemic and lymphatic diseases, NLR Family, Pyrin Domain-Containing 3 Protein, Agammaglobulinaemia Tyrosine Kinase, medicine, Animals, Humans, Bruton's tyrosine kinase, Colitis, Child, B cell, Aged, Aged, 80 and over, Mice, Knockout, integumentary system, biology, Kinase, Genetic Diseases, X-Linked, Inflammasome, General Medicine, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, chemistry, 030220 oncology & carcinogenesis, Ibrutinib, biology.protein, Cancer research, Female, Research Article, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5065c11282ca001a45a6d2d7dd148c30
https://doi.org/10.1172/jci128322

المؤلفون: Stanislav V. Sosnovtsev, Natalia Shulzhenko, Manoj Gurung, Michael Yao, Dariia Vyshenska, Xiaoxi Dong, Stephany Vasquez-Perez, Ivan J. Fuss, Ekaterina Peremyslova, Martha Quezado, Warren Strober, Kim Montgomery-Recht, Andrey Morgun, Renee L. Greer

المصدر: Clinical Immunology. 197:139-153

مصطلحات موضوعية: Acinetobacter baumannii, Male, 0301 basic medicine, Malabsorption, Gene Expression, 0302 clinical medicine, RNA, Ribosomal, 16S, 2.1 Biological and endogenous factors, Immunology and Allergy, Enteropathy, Aetiology, Mucosal, Duodenitis, Bacterial, RNA, Bacterial, 030220 oncology & carcinogenesis, Female, medicine.symptom, 16S, Immunology, Down-Regulation, Inflammation, Article, 03 medical and health sciences, Immune system, Malabsorption Syndromes, Clinical Research, Genetics, medicine, Humans, Microbiome, Immunity, Mucosal, Nutrition, Ribosomal, business.industry, Inflammatory and immune system, Common variable immunodeficiency, Immunity, Lipid metabolism, Lipid Metabolism, medicine.disease, Immunoglobulin A, Gastrointestinal Microbiome, Common Variable Immunodeficiency, 030104 developmental biology, Mucosal immunology, RNA, Interferons, Digestive Diseases, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5881e2c9e08d12215f9d63a9cc2be84a
https://doi.org/10.1016/j.clim.2018.09.008

المؤلفون: Martha Quezado, Lindsey Albenberg, Michael Yao, Atiye Aktay, Kim Montgomery-Recht, Liming Mao, Atsushi Kitani, Andrew J. Oler, Judith R. Kelsen, Ivan J. Fuss, Warren Strober, Morgan Similuk

المصدر: Journal of Clinical Investigation. 128:1793-1806

مصطلحات موضوعية: Male, 0301 basic medicine, Gene isoform, Inflammasomes, Interleukin-1beta, Mutation, Missense, medicine.disease_cause, Monocytes, Serine, Dephosphorylation, 03 medical and health sciences, 0302 clinical medicine, Crohn Disease, Downregulation and upregulation, Loss of Function Mutation, NLR Family, Pyrin Domain-Containing 3 Protein, medicine, Humans, Protein Isoforms, Missense mutation, Phosphorylation, Exome sequencing, Mutation, Whole Genome Sequencing, integumentary system, Chemistry, Ubiquitination, Inflammasome, General Medicine, Molecular biology, Neoplasm Proteins, CARD Signaling Adaptor Proteins, HEK293 Cells, 030104 developmental biology, Amino Acid Substitution, 030220 oncology & carcinogenesis, Female, Research Article, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad5f272d9f0fa4b73b2ed148da1b3ce
https://doi.org/10.1172/jci98642

المؤلفون: Mohammed F Sadiyah, Ira Palmer, Anwar A. Sayed, Ahmad Khoder, Joshua Kaufman, Warren Strober, Alejandro V. Villarino, Paul T. Wingfield, Michael Mueller, Majid Kazemian, Joshua McElwee, Ahmed N. Hegazy, Behdad Afzali, Fred P. Davis, Julia Keith, Jason D. Hughes, Hong-Wei Sun, Charlotte O'Brien, Holm H. Uhlig, Michelle A. Linterman, Yu Zhang, Arian Laurence, Nichola Cooper, John J. O'Shea, Ine Vanderleyden, Dalia Kasperaviciute, Timothy J. Aitman, Rahul Roychoudhuri, Olena Kamenyeva, Juha Grönholm, Kim Montgomery-Recht, Ivan J. Fuss, Nicholas P. Restifo, Norman R. Watts, Peter Kelleher, Jana Vandrovcova, Michael J. Lenardo

المساهمون: Westminster Medical School Research Trust, Imperial College Healthcare NHS Trust- BRC Funding, Leuka, Zhang, Yu [0000-0002-6904-0372], Villarino, Alejandro V [0000-0001-8068-2176], Roychoudhuri, Rahul [0000-0002-5392-1853], Apollo - University of Cambridge Repository

المصدر: Nature immunology
Afzali, B, Grönholm, J, Vandrocova, J, O'Brien, C, Sun, H-W, Vanderleyden, I, Davis, F P, Khoder, A, Zhang, Y, Hegazy, A N, Villarino, A V, Palmer, I W, Kaufman, J, Watts, N R, Kazemian, M, Kamenyeva, O, Keith, J, Sayed, A, Kasperaviciute, D, Mueller, M, Hughes, J D, Fuss, I J, Sadiyah, M F, Montgomery-Recht, K, McElwee, J, Restifo, N P, Strober, W, Linterman, M A, Wingfield, P T, Uhlig, H H, Roychoudhuri, R, Aitman, T J, Kelleher, P, Lenardo, M J, O'Shea, J J, Cooper, N & Laurence, A D J 2017, ' BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency ', Nature Immunology, vol. 18, no. 7, pp. 813-823 . https://doi.org/10.1038/ni.3753
Afzali, B, Grönholm, J, Vandrovcova, J, O'Brien, C, Sun, H-W, Vanderleyden, I, Davis, F P, Khoder, A, Zhang, Y, Hegazy, A N, Villarino, A V, Palmer, I W, Kaufman, J, Watts, N R, Kazemian, M, Kamenyeva, O, Keith, J, Sayed, A, Kasperaviciute, D, Mueller, M, Hughes, J D, Fuss, I J, Sadiyah, M F, Montgomery-Recht, K, McElwee, J, Restifo, N P, Strober, W, Linterman, M A, Wingfield, P T, Uhlig, H H, Roychoudhuri, R, Aitman, T J, Kelleher, P, Lenardo, M J, O'Shea, J J, Cooper, N & Laurence, A D J 2017, ' BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency ', Nature Immunology . https://doi.org/10.1038/ni.3753

مصطلحات موضوعية: 0301 basic medicine, Male, Pancytopenia, AUTOIMMUNITY, Genome-wide association study, CELL DIFFERENTIATION, Haploinsufficiency, Adrenal Cortex Hormones, Recurrence, Plasma cell differentiation, Immunology and Allergy, Respiratory Tract Infections, Immunodeficiency, Genetics, Lymphocyte differentiation, Syndrome, Middle Aged, Colitis, 3. Good health, Pedigree, TRANSCRIPTION FACTORS, Basic-Leucine Zipper Transcription Factors, PLASMA-CELL-DIFFERENTIATION, 1107 Immunology, B-CELLS, Female, FUNCTIONAL PREDICTIONS, Life Sciences & Biomedicine, Adult, Heterozygote, SUSCEPTIBILITY LOCI, SEQUENCING DATA, Fever, DATABASE, Immunology, COMMON VARIABLE IMMUNODEFICIENCY, Polymorphism, Single Nucleotide, Article, CLASSIFICATION, Autoimmune Diseases, 03 medical and health sciences, Young Adult, Lymphopenia, Journal Article, medicine, Humans, GENOME-WIDE ASSOCIATION, Gene, METAANALYSIS, Science & Technology, IDENTIFICATION, business.industry, Common variable immunodeficiency, Immunologic Deficiency Syndromes, medicine.disease, RISK LOCI, 030104 developmental biology, Mutation, Splenomegaly, Primary immunodeficiency, T-CELLS, business, Tomography, X-Ray Computed

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a182df8067dd7dc1d6e21daa5800d19
http://ora.ox.ac.uk/objects/uuid:

المؤلفون: Stanislav V. Sosnovtsev, Ivan J. Fuss, Stephany Vasquez-Perez, Andrey Morgun, Renee L. Greer, Kate Peremyslova, Manoj Gurung, Natalia Shulzhenko, Warren Strober, Kim Montgomery-Recht, Xiaoxi Dong, Michael Yao, Dariia Vyshenska

المصدر: Gastroenterology. 152:S997-S998

مصطلحات موضوعية: 0301 basic medicine, 03 medical and health sciences, 030104 developmental biology, Hepatology, Immunology, Gastroenterology, medicine, Enteropathy, Biology, medicine.disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2bbdf388bea86408131236620dc99243
https://doi.org/10.1016/s0016-5085(17)33381-4

المؤلفون: Atiye N. Aktay, Liming Mao, Kim Montgomery-Recht, Warren Strober, Ivan J. Fuss, Martha Quezado, Judith R. Kelsen, Atsushi Kitani, Lindsey Albenberg, Andrew J. Oler, Morgan Similuk, Michael Yao

المصدر: Gastroenterology. 154:S-1026

مصطلحات موضوعية: Crohn's disease, Hepatology, business.industry, Mutation (genetic algorithm), Gastroenterology, Cancer research, Medicine, NLRP3 inflammasome activation, business, medicine.disease, Blockade

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c0fbfec1700f688f04be9f25af7802f7
https://doi.org/10.1016/s0016-5085(18)33435-8