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1
المؤلفون: Gregor James Macdonald, Phillip Jeffrey, Nigel E. Austin, Vong Antonio Kuok Keong, Graham J. Riley, Izzy Boyfield, Christopher N. Johnson, Alexander Baxter Smith, Clive Leslie Branch, Geoffrey Stemp, Kim Y. Avenell, Michael S. Hadley, Kevin M. Thewlis, Martyn D. Wood, David John Nash
المصدر: Bioorganic & Medicinal Chemistry Letters. 11:685-688
مصطلحات موضوعية: Models, Molecular, Indoles, Isoindoles, Stereochemistry, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, CHO Cells, Biochemistry, Chemical synthesis, Radioligand Assay, chemistry.chemical_compound, Dopamine receptor D3, Cricetinae, Drug Discovery, medicine, Animals, Humans, Receptor, Molecular Biology, Molecular Structure, Receptors, Dopamine D2, Chemistry, Tetrahydroisoquinoline, Organic Chemistry, Receptors, Dopamine D3, Brain, Rats, Bioavailability, Drug Design, Dopamine Antagonists, Molecular Medicine, Selectivity
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2
المؤلفون: Izzy Boyfield, Martyn D. Wood, F Jewitt, Graham J. Riley, Kim Y. Avenell, David John Nash
المصدر: European Journal of Pharmacology. 407:47-51
مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, Quinpirole, Receptors, Dopamine D2, Chemistry, Dopaminergic, Receptors, Dopamine D3, Azepines, CHO Cells, Piperazines, Dopamine receptor D1, BP-897, Endocrinology, D2-like receptor, Dopamine receptor, Dopamine receptor D3, Cricetinae, Internal medicine, Dopamine receptor D2, Dopamine Agonists, medicine, Animals, Humans, Endogenous agonist, medicine.drug
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3
المؤلفون: David John Nash, Geoffrey Stemp, Michael S. Hadley, Kim Y. Avenell, Graham J. Riley, Izzy Boyfield, Christopher N. Johnson
المصدر: Bioorganic & Medicinal Chemistry Letters. 9:2715-2720
مصطلحات موضوعية: Agonist, Tetrahydronaphthalenes, Bicyclic molecule, Tertiary amine, Receptors, Dopamine D2, Stereochemistry, medicine.drug_class, Chemistry, Organic Chemistry, Clinical Biochemistry, Receptors, Dopamine D3, Pharmaceutical Science, Carboxamide, Biochemistry, Affinities, Chemical synthesis, Heterocyclic Compounds, Dopamine receptor D3, Drug Discovery, medicine, Molecular Medicine, Selectivity, Molecular Biology, Protein Binding
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4
المؤلفون: Michael S. Hadley, Stephen A. Smith, Kim Y. Avenell, David John Nash, Geoffrey Stemp, Kevin M. Thewlis, Martyn C. Coldwell, Clive Leslie Branch, Nigel E. Austin, Vong Antonio Kuok Keong, Graham J. Riley, Izzy Boyfield, Christopher N. Johnson, Rachel Stacey, Phillip Jeffrey, Amana Johns
المصدر: Bioorganic & Medicinal Chemistry Letters. 9:179-184
مصطلحات موضوعية: Models, Molecular, Receptors, Dopamine D2, Tetrahydroisoquinoline, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Receptors, Dopamine D3, Substituent, Brain, Pharmaceutical Science, Isoquinolines, Biochemistry, Rats, chemistry.chemical_compound, chemistry, Dopamine receptor D3, Dopamine receptor D2, Drug Discovery, Animals, Molecular Medicine, Selectivity, Molecular Biology
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5
المؤلفون: Kim Y. Avenell, Izzy Boyfield, Christopher N. Johnson, Geoffrey Stemp, Michael S. Hadley, David John Nash, Graham J. Riley
المصدر: ChemInform. 30
مصطلحات موضوعية: Chemistry, Dopamine receptor D3, Stereochemistry, General Medicine, Selectivity, Affinities
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6
المؤلفون: Vong Antonio Kuok Keong, Izzy Boyfield, Christopher N. Johnson, Alexander Baxter Smith, Graham J. Riley, Geoffrey Stemp, Gregor James Macdonald, David John Nash, Phillip Jeffrey, Nigel E. Austin, Michael S. Hadley, Martyn D. Wood, Kim Y. Avenell, Clive Leslie Branch, Kevin M. Thewlis
المصدر: Bioorganicmedicinal chemistry letters. 10(22)
مصطلحات موضوعية: Benzazepines, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Biochemistry, Dopamine receptor D3, Dopamine, Tetrahydroisoquinolines, Drug Discovery, Nitriles, Functional selectivity, medicine, Animals, Receptor, Molecular Biology, Chemistry, Receptors, Dopamine D2, Organic Chemistry, Receptors, Dopamine D3, Receptor antagonist, Rats, Quinolines, Molecular Medicine, Selectivity, medicine.drug
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7
المؤلفون: and Carole Routledge, Nigel E. Austin, Tracey Ashmeade, Charlie Reavill, A. Jacqueline Hunter, Clive Leslie Branch, Derek N. Middlemiss, Geoffrey Stemp, Vong Antonio Kuok Keong, Kevin M. Thewlis, Izzy Boyfield, Christopher N. Johnson, Jim J. Hagan, Phillip Jeffrey, Graham J. Riley, David John Nash, Martyn D. Wood, Kim Y. Avenell, Michael S. Hadley
المصدر: Journal of medicinal chemistry. 43(9)
مصطلحات موضوعية: Central Nervous System, Male, Stereochemistry, Microdialysis, Biological Availability, CHO Cells, Rats, Sprague-Dawley, Radioligand Assay, Dopamine receptor D3, Dopamine receptor D2, Cricetinae, Tetrahydroisoquinolines, Drug Discovery, Nitriles, Animals, Humans, Receptor, Catalepsy, biology, Chemistry, Receptors, Dopamine D2, Antagonist, Receptors, Dopamine D3, Cytochrome P450, Brain, Bioavailability, Prolactin, Rats, biology.protein, Quinolines, Molecular Medicine, Dopamine Antagonists, Selectivity, Linker, Half-Life
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8
المؤلفون: Geoffrey Stemp, Emma E. Scott, Izzy Boyfield, David John Nash, Graham J. Riley, Martyn C. Coldwell, Philip M. Jeffrey, Maureen A.M. Healy, Christopher N. Johnson, Rachel Stacey, Kim Y. Avenell, Kevin M. Thewlis, Stephen A. Smith, Michael S. Hadley
المصدر: Bioorganicmedicinal chemistry letters. 8(20)
مصطلحات موضوعية: Tetrahydronaphthalenes, medicine.drug_class, Stereochemistry, Chemistry, Metabolic Clearance Rate, Organic Chemistry, Clinical Biochemistry, Receptors, Dopamine D3, Pharmaceutical Science, Carboxamide, Ligand (biochemistry), Biochemistry, Chemical synthesis, Rats, Dopamine D2 Receptor Antagonists, In vivo, Dopamine receptor D3, Drug Discovery, medicine, Functional selectivity, Molecular Medicine, Animals, Selectivity, Chirality (chemistry), Molecular Biology