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المؤلفون: Kip Nalley, Devanjan Sikder, Thomas Kodadek
المصدر: Cell. 127:261-264
مصطلحات موضوعية: Transcriptional Activation, Proteasome Endopeptidase Complex, 0303 health sciences, Time Factors, Models, Genetic, Transcription, Genetic, biology, Ubiquitin, Biochemistry, Genetics and Molecular Biology(all), General Biochemistry, Genetics and Molecular Biology, Cell biology, 03 medical and health sciences, 0302 clinical medicine, Trans-Activators, biology.protein, Animals, Humans, Proteasome endopeptidase complex, Protein Processing, Post-Translational, 030217 neurology & neurosurgery, 030304 developmental biology
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المؤلفون: Kip Nalley, Stephen Albert Johnston, Thomas Kodadek
المصدر: Nature. 442:1054-1057
مصطلحات موضوعية: Herpes simplex virus protein vmw65, Multidisciplinary, medicine.diagnostic_test, Activator (genetics), Proteolysis, Biology, DNA-binding protein, Cell biology, Transactivation, Biochemistry, Gene expression, medicine, Chromatin immunoprecipitation, Transcription factor
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المؤلفون: Kevin J. Tomaselli, Julia Herrmann, Robert O. Sayers, Joe C. Wu, Lalitha Kodandapani, Kathy G. Jahangiri, Craig D. Fisher, David T. Winn, Edward D. Robinson, Steven P. Meduna, Robert J. Ternansky, Pauline Yeo, Karen L. Valentino, Jose-Luis Diaz, Vincent J. Kalish, Steven D. Linton, Kristen Sebring, Robert A. Armstrong, Joseph F. Krebs, Niel C. Hoglen, Alfred P. Spada, Brad P. Hirakawa, Ning Chen, Brett R. Ullman, Brett Weylan Ching, Cheng-zhi Zhang, Xu Bai, Xin Gu, Kip Nalley, Long-Shiuh Chen, Patricia L. Gladstone, Jeff McQuiston, Teresa Aja, Todd Groessl, Donald S. Karanewsky, Suzanne Weeks, Lawrence C. Fritz, Patricia C. Contreras
المصدر: Journal of Medicinal Chemistry. 48:6779-6782
مصطلحات موضوعية: Adult, Biological Availability, Phases of clinical research, Apoptosis, Pharmacology, Jurkat Cells, Mice, Structure-Activity Relationship, Liver disease, Pharmacokinetics, In vivo, Drug Discovery, medicine, Animals, Humans, Aspartate Aminotransferases, Pentanoic Acids, Caspase, Liver injury, Cholestasis, Clinical Trials, Phase I as Topic, biology, Caspase 3, Chemistry, Liver Diseases, Alanine Transaminase, Hepatitis C, Chronic, medicine.disease, Caspase Inhibitors, In vitro, Rats, Liver, Biochemistry, Enzyme inhibitor, Hepatocytes, biology.protein, Molecular Medicine, Half-Life
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المؤلفون: Robert Smidt, Silvio Roggo, Julia Herrmann, Edward D. Robinson, Kathy G. Jahangiri, Teresa Aja, Kip Nalley, Thomas L. Deckwerth, Giorgio Rovelli, Kevin J. Tomaselli, Joe C. Wu, Bastian Hengerer, Steven P. Meduna, André Sauter, Jose-Luis Diaz, Joerg Kallen, Albert Schmitz, Donald S. Karanewsky, Brett R. Ullman, Steven D. Linton, Christoph Wiessner, Robert J. Ternansky, Peter R. Allegrini, Robert O. Sayers
المصدر: Bioorganic & Medicinal Chemistry Letters. 14:2685-2691
مصطلحات موضوعية: Peptidomimetic, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Oxamyl, Apoptosis, Peptide, Biochemistry, Cell Line, Inhibitory Concentration 50, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Humans, Structure–activity relationship, Molecular Biology, Caspase, chemistry.chemical_classification, Dipeptide, biology, Organic Chemistry, Neurodegenerative Diseases, Dipeptides, Caspase Inhibitors, In vitro, Stroke, Kinetics, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Carbamates
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المؤلفون: Edward D. Robinson, Silvio Roggo, Joe C. Wu, Robert J. Ternansky, Jose-Luis Diaz, Teresa Aja, Kevin J. Tomaselli, Steven P. Meduna, Vincent J. Kalish, Donald S. Karanewsky, Robert O. Sayers, Albert Schmitz, Brett R. Ullman, Julia Herrmann, Kip Nalley, Thomas L. Deckwerth
المصدر: Bioorganic & Medicinal Chemistry Letters. 13:3623-3626
مصطلحات موضوعية: chemistry.chemical_classification, Programmed cell death, biology, Chemistry, Organic Chemistry, Clinical Biochemistry, Leaving group, Pharmaceutical Science, Inflammation, Cysteine Proteinase Inhibitors, Caspase Inhibitors, Biochemistry, In vitro, Structure-Activity Relationship, Enzyme, Enzyme inhibitor, Drug Discovery, biology.protein, medicine, Molecular Medicine, Structure–activity relationship, medicine.symptom, Molecular Biology, Caspase
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المؤلفون: Teresa Aja, André Sauter, Donald S. Karanewsky, Markus Rudin, Rachel May, Peter R. Allegrini, Bastian Hengerer, Robert O. Sayers, Christoph Wiessner, Steve Linton, Albert Schmitz, Giorgio Rovelli, Kevin J. Tomaselli, Patricia C. Contreras, Joe C. Wu, Silvio Roggo, Kip Nalley, Lisa M. Adams, Thomas L. Deckwerth
المصدر: Drug Development Research. 52:579-586
مصطلحات موضوعية: biology, business.industry, Central nervous system, Ischemia, Caspase 3, Pharmacology, medicine.disease, Neuroprotection, medicine.anatomical_structure, Apoptosis, Anesthesia, medicine.artery, Drug Discovery, Middle cerebral artery, medicine, biology.protein, Artery occlusion, business, Caspase
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المؤلفون: Natasha Milinovikj, Maher Youssif, Andre Goy, K. Stephen Suh, Elyssa Schecter, Fathi Elloumi, Kip Nalley, Steven Russell, Andrew L. Pecora, Sreeja Sarojini
المصدر: Journal of Oncology, Vol 2013 (2013)
Journal of Oncologyمصطلحات موضوعية: business.industry, Clinical study design, Medical record, Review Article, Bioinformatics, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282, Oncology, Tissue bank, Donation, Medicine, Personalized medicine, Biomarker discovery, business, Tissue Banking, Patient education
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المؤلفون: Kip Nalley
المصدر: Enzyme Inhibitors Series ISBN: 9781420045406
Design of Caspase Inhibitors as Potential Clinical Agentsمصطلحات موضوعية: biology, Chemistry, Kinetics, biology.protein, Biophysics, Caspase, Catalysis
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::448182de44bf95cd6190b68a392d8fd2
https://doi.org/10.1201/9781420045413.ch4 -
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المؤلفون: Kip Nalley, Anwarul Ferdous, Stephen Albert Johnston, Melissa A. O'Neal, Devanjan Sikder, Thomas Kodadek
مصطلحات موضوعية: Models, Molecular, Saccharomyces cerevisiae Proteins, Biology, DNA-binding protein, Article, Phosphorylation cascade, Serine, Humans, Point Mutation, Binding site, Phosphorylation, Promoter Regions, Genetic, Molecular Biology, Transcription factor, Binding Sites, Activator (genetics), Lysine, Ubiquitination, Promoter, DNA-binding domain, DNA, Protein Structure, Tertiary, DNA-Binding Proteins, Biochemistry, Biotechnology, HeLa Cells, Transcription Factors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8074758c1d2b5941f7991105841dfb7a
https://europepmc.org/articles/PMC4451857/ -
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المؤلفون: Kip Nalley, Devanjan Sikder, Thomas Kodadek, Thomas G. Gillette, Stephen Albert Johnston, Anwarul Ferdous
المصدر: Genesdevelopment. 21(1)
مصطلحات موضوعية: Transcriptional Activation, Chromatin Immunoprecipitation, Proteasome Endopeptidase Complex, Saccharomyces cerevisiae Proteins, Transcription, Genetic, ATPase, Blotting, Western, Saccharomyces cerevisiae, DNA-binding protein, Adenosine Triphosphate, Ubiquitin, Gene Expression Regulation, Fungal, Genetics, Humans, Promoter Regions, Genetic, Transcription factor, Adenosine Triphosphatases, biology, Activator (genetics), Promoter, TATA Box, DNA-Binding Proteins, Biochemistry, Proteasome, biology.protein, Trans-Activators, Chromatin immunoprecipitation, Developmental Biology, HeLa Cells, Transcription Factors, Research Paper
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f7b893e4d3c93f40d162d7e0f284e6
https://pubmed.ncbi.nlm.nih.gov/17167105
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