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المؤلفون: Yunpeng Ye, Terence L. Wu, Jakub Toczek, Jae-Joon Jung, Kiran Babu Gona, Mousumi Ghosh, Mehran M. Sadeghi, Mahmoud Razavian, Jiasheng Zhang, Hye-Yeong Kim, Jinah Han, Reza Golestani
المصدر: Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, Multidisciplinary, Arginine, Chemistry, Transgene, Science, Inflammation, Matrix metalloproteinase, In vitro, 3. Good health, law.invention, 03 medical and health sciences, 030104 developmental biology, Biochemistry, law, medicine, Recombinant DNA, Medicine, medicine.symptom, Conjugate
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المؤلفون: Yunpeng Ye, Laurent Devel, Mani Salarian, Mehran M. Sadeghi, Saranya Rajendran, Arvene Golbazi, Parnaz Boodagh, Nowshin Sanzida, Kiran Babu Gona, Terence L. Wu, Jakub Toczek, Jae-Joon Jung, Gunjan Kukreja
المساهمون: Yale University School of Medicine, Yale University [New Haven], Médicaments et Technologies pour la Santé (MTS), Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), United States Department of Health & Human Services National Institutes of Health (NIH) - USA : NIH grant R01HL138567, NIH training grants 5T32HL98069, 5T32HL007950 and S10RR018039, VA Merit grant I01BX004038, Yale School of Medicine [New Haven, Connecticut] (YSM)
المصدر: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2020, 63 (23), pp.15037-15049. ⟨10.1021/acs.jmedchem.0c01514⟩
Journal of Medicinal Chemistry, 2020, 63 (23), pp.15037-15049. ⟨10.1021/acs.jmedchem.0c01514⟩
J Med Chemمصطلحات موضوعية: education, Matrix Metalloproteinase Inhibitors, Pharmacology, Matrix metalloproteinase, Hydroxamic Acids, 01 natural sciences, Macrophage elastase, Article, Structure-Activity Relationship, 03 medical and health sciences, Downregulation and upregulation, Matrix Metalloproteinase 12, Drug Discovery, medicine, Animals, Humans, Rupture risk, reproductive and urinary physiology, 030304 developmental biology, 0303 health sciences, Molecular Structure, Chemistry, Organotechnetium Compounds, medicine.disease, Abdominal aortic aneurysm, female genital diseases and pregnancy complications, Molecular Imaging, 3. Good health, 0104 chemical sciences, Mice, Inbred C57BL, body regions, 010404 medicinal & biomolecular chemistry, Drug Design, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, Molecular Medicine, Blood clearance, Radiopharmaceuticals, Molecular imaging, Oligopeptides, Ex vivo, Aortic Aneurysm, Abdominal
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المؤلفون: Jakub Toczek, Mani Salarian, Parnaz Boodagh, Mean Ghim, Jinah Han, Jae-Joon Jung, Gunjan Kukreja, Jiasheng Zhang, Xinran Liu, Nowshin Sanzida, Kiran Babu Gona, Linyan Wei, Morven Graham, Saranya Rajendran, Mehran M. Sadeghi
المصدر: Theranostics
مصطلحات موضوعية: Apolipoprotein E, Male, Biodistribution, Pathology, medicine.medical_specialty, Medicine (miscellaneous), Inflammation, macromolecular substances, 030204 cardiovascular system & hematology, Pathogenesis, 03 medical and health sciences, Mice, 0302 clinical medicine, Apolipoproteins E, abdominal aortic aneurysm, In vivo, medicine, Animals, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), Aorta, 030304 developmental biology, 0303 health sciences, Phagocytes, CD68, business.industry, Angiotensin II, Macrophages, computed tomography, medicine.disease, molecular imaging, Abdominal aortic aneurysm, Mice, Inbred C57BL, Disease Models, Animal, inflammation, cardiovascular system, nanoparticles, medicine.symptom, business, Tomography, X-Ray Computed, Aortic Aneurysm, Abdominal, Research Paper
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المؤلفون: Hye-Yeong Kim, Yunpeng Ye, Olivier Lequin, Jae-Joon Jung, Kiran Babu Gona, Vincent Dive, Fabrice Beau, Mahmoud Razavian, Isabelle Correia, Jakub Toczek, Mehran M. Sadeghi, Dimitris Georgiadis, Laurent Devel, Thomas Bordenave
المساهمون: Université Joseph Fourier - Grenoble 1 (UJF), Centre de recherche du CEA/DSV/iBiTec-S/SIMOPRO, Université Pierre et Marie Curie - Paris 6 (UPMC), Service d'Ingénierie Moléculaire pour la Santé (ex SIMOPRO) (SIMoS), Médicaments et Technologies pour la Santé (MTS), Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Yale School of Medicine [New Haven, Connecticut] (YSM), University of Athens, Athens, Laboratoire des biomolécules (LBM UMR 7203), Chimie Moléculaire de Paris Centre (FR 2769), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Département de Chimie - ENS Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2019, 62 (21), pp.9743-9752. ⟨10.1021/acs.jmedchem.9b01186⟩
J Med Chem
Journal of Medicinal Chemistry, 2019, 62 (21), pp.9743-9752. ⟨10.1021/acs.jmedchem.9b01186⟩مصطلحات موضوعية: Male, Biodistribution, [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging, Matrix metalloproteinase, Matrix Metalloproteinase Inhibitors, 01 natural sciences, Article, 03 medical and health sciences, Aortic aneurysm, Mice, In vivo, medicine.artery, Matrix Metalloproteinase 12, Drug Discovery, medicine, Animals, Humans, [CHIM]Chemical Sciences, Tissue Distribution, Radioactive Tracers, Aorta, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, 0303 health sciences, Metalloproteinase, Radiochemistry, Chemistry, Organotechnetium Compounds, medicine.disease, Molecular biology, In vitro, 0104 chemical sciences, Molecular Imaging, Up-Regulation, Mice, Inbred C57BL, 010404 medicinal & biomolecular chemistry, cardiovascular system, Molecular Medicine, Molecular imaging, Aortic Aneurysm, Abdominal
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المؤلفون: Kiran Babu Gona, Jordi Llop, Zuriñe Baz, Krishna R. Pulagam, Irina Estrela-Lopis, Carolin Zilberfain, Unai Cossío, Vanessa Gómez-Vallejo, Jan Meijer
المصدر: Molecules
Molecules, Vol 24, Iss 19, p 3609 (2019)
Volume 24
Issue 19مصطلحات موضوعية: positron emission tomography, HT1080, Pharmaceutical Science, Nanoparticle, Metal Nanoparticles, 02 engineering and technology, Spectrum Analysis, Raman, 01 natural sciences, Analytical Chemistry, Polyethylene Glycols, Iodine Radioisotopes, chemistry.chemical_compound, Mice, iodine-124, Drug Discovery, Tissue Distribution, Chemistry, 021001 nanoscience & nanotechnology, Chemistry (miscellaneous), Colloidal gold, cobalt bis(dicarbollide), ddc:540, Molecular Medicine, 0210 nano-technology, inorganic chemicals, Biodistribution, Transplantation, Heterologous, chemistry.chemical_element, Boron Neutron Capture Therapy, Polyethylene glycol, 010402 general chemistry, Article, radiolabelling, lcsh:QD241-441, lcsh:Organic chemistry, In vivo, Cell Line, Tumor, PEG ratio, Animals, Humans, Physical and Theoretical Chemistry, Particle Size, Boron, Organic Chemistry, Tetrahydropyran, boron neutron capture therapy, gold nanoparticles, 0104 chemical sciences, Positron-Emission Tomography, Gold, Nuclear chemistry
وصف الملف: application/pdf
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المؤلفون: Jiasheng Zhang, Jae-Joon Jung, Hye-Yeong Kim, Mahmoud Razavian, Kiran Babu Gona, Jakub Toczek, Jack A. Elias, Mehran M. Sadeghi, Robert J. Homer, Reza Golestani, Chun Geun Lee, Yunpeng Ye
المصدر: Journal of Nuclear Medicine. 58:138-143
مصطلحات موضوعية: 0301 basic medicine, Pathology, medicine.medical_specialty, Single Photon Emission Computed Tomography Computed Tomography, Mice, Transgenic, Inflammation, 030204 cardiovascular system & hematology, Matrix metalloproteinase, Sensitivity and Specificity, Mice, 03 medical and health sciences, 0302 clinical medicine, In vivo, Pulmonary fibrosis, Animals, Inflammation/Infectious Disease, Medicine, Radiology, Nuclear Medicine and imaging, Lung, business.industry, CD68, Reproducibility of Results, Pneumonia, respiratory system, medicine.disease, Matrix Metalloproteinases, Molecular Imaging, 030104 developmental biology, medicine.anatomical_structure, Interleukin 13, Airway Remodeling, medicine.symptom, business, Ex vivo
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7269709e521dcf1b94a96441d5bfd4
https://doi.org/10.2967/jnumed.116.176198 -
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المؤلفون: Jacek Koziorowski, Irina Manea, Vanessa Gómez-Vallejo, Jordi Llop, Kiran Babu Gona, Jonas Malmquist
المصدر: Boron-Based Compounds
مصطلحات موضوعية: Nuclear imaging, Chemistry, Isotopes of bromine, Radiochemistry, Boron clusters, Neutron irradiation, Preclinical imaging
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d037733db892278dd54a972f3075b916
https://doi.org/10.1002/9781119275602.ch2.5 -
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المؤلفون: George L. Trainor, Jun Dai, Arvind Mathur, Francis Y. Lee, Sunilkumar Mandal, Yingru Zhang, Richard Rampulla, Kiran Babu Gona, Patrice Gill, Raja Thiruvenkadam, Victor R. Guarino, Wen-Ching Han, Ding Ren Shen, Aaron Balog, Mary Ellen Cvijic, Dauh-Rurng Wu, Gregory D. Vite, Krista Menard, Anne Rose, Sathiah Kandula, Ashvinikumar V. Gavai, Weifang Shan, John T. Hunt, Asoka Ranasinghe, Kelly McGlinchey, Richard A. Westhouse, Claude A. Quesnelle, Derek J. Norris, Mei-Li Wen, Ronald E. White, Kamalraj Thiyagarajan
المصدر: Bioorganic & Medicinal Chemistry Letters. 25:1905-1909
مصطلحات موضوعية: Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, Antineoplastic Agents, Pharmacology, Biochemistry, Mice, Structure-Activity Relationship, In vivo, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Receptor, Solid tumor, Molecular Biology, Cell Proliferation, Benzodiazepinones, Dose-Response Relationship, Drug, Molecular Structure, Receptors, Notch, Chemistry, Organic Chemistry, Biological activity, Neoplasms, Experimental, medicine.disease, Leukemia, Orally active, Microsomes, Liver, Molecular Medicine, Drug Screening Assays, Antitumor
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المؤلفون: Jaya Lakshmi V. N. P. Thota, Zuriñe Baz, Kiran Babu Gona, Vanessa Gómez-Vallejo, Jordi Llop
المصدر: Molecules
Volume 20
Issue 5
Pages 7495-7508
Molecules, Vol 20, Iss 5, Pp 7495-7508 (2015)مصطلحات موضوعية: Boron Compounds, positron emission tomography, Stereochemistry, Pharmaceutical Science, Ring (chemistry), Article, radiolabelling, Analytical Chemistry, lcsh:QD241-441, chemistry.chemical_compound, lcsh:Organic chemistry, Breast cancer cell line, In vivo, Labelling, Drug Discovery, Benzothiazoles, Carbon Radioisotopes, carbon-11, Physical and Theoretical Chemistry, m-carborane, Organic Chemistry, Halogenation, benzothiazole, In vitro, Benzothiazole, chemistry, Chemistry (miscellaneous), Positron-Emission Tomography, Molecular Medicine, Amine gas treating, Radiopharmaceuticals
وصف الملف: application/pdf
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المؤلفون: Kiran Babu Gona, Boguslaw Szczupak, Juan Carlos Chara, María Domercq, Abraham Martín, Federico N. Soria, Alberto Pérez-Samartín, Carlos Matute, Jordi Llop
المصدر: Journal of Clinical Investigation. 124:3645-3655
مصطلحات موضوعية: Amino Acid Transport System y+, Vesicular Glutamate Transport Proteins, Antiporter, Glycine, Glutamic Acid, Glutamate Plasma Membrane Transport Proteins, Biology, Benzoates, Receptors, N-Methyl-D-Aspartate, Brain Ischemia, Rats, Sprague-Dawley, Mice, Glutamate homeostasis, Animals, Mice, Knockout, Mice, Inbred C3H, Cell Death, Pyramidal Cells, Glutamate receptor, General Medicine, Glutamic acid, Rats, Cell biology, nervous system, Biochemistry, Metabotropic glutamate receptor, Commentary, NMDA receptor, Ion Channel Gating
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