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1
المؤلفون: Rienk Offringa, Lisa Kötzner, Bayard Huck, Klaus Urbahns
المصدر: Nature reviews. Drug discovery. 21(11)
مصطلحات موضوعية: Pharmacology, Neoplasms, T-Lymphocytes, Drug Discovery, Tumor Microenvironment, Humans, Cytokines, General Medicine, Immunotherapy
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2
المؤلفون: Johannes Landmann, Tanja Knuplez, Christoph Kerpen, Nikolai V. Ignat'ev, Ludwig Zapf, Rüdiger Bertermann, Kristina A. M. Maibom, Tobias Bischof, Fabian Keppner, Eva-Maria Tanzer Krauel, Carl Deutsch, Leon Schneider, Klaus Urbahns, Michael Hailmann, Maik Finze
المصدر: Chemistry (Weinheim an Der Bergstrasse, Germany)
مصطلحات موضوعية: Hydrocarbons, Fluorinated, Hot Paper, Ligands, 010402 general chemistry, 01 natural sciences, Medicinal chemistry, Catalysis, Hydrolysis, chemistry.chemical_compound, N ligands, Nucleophilic substitution, Sandmeyer reaction, Molecule, silver, fluorinated ligands, Amines, Amination, chemistry.chemical_classification, Trifluoromethyl, Full Paper, 010405 organic chemistry, Organic Chemistry, amination, General Chemistry, Full Papers, 0104 chemical sciences, Amino acid, chemistry, copper, Reagent, Indicators and Reagents, ddc:546
وصف الملف: application/pdf
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3دورية أكاديمية
المؤلفون: Paul A Clarke, Maria-Jesus Ortiz-Ruiz, Robert TePoele, Olajumoke Adeniji-Popoola, Gary Box, Will Court, Stephanie Czasch, Samer El Bawab, Christina Esdar, Ken Ewan, Sharon Gowan, Alexis De Haven Brandon, Phillip Hewitt, Stephen M Hobbs, Wolfgang Kaufmann, Aurélie Mallinger, Florence Raynaud, Toby Roe, Felix Rohdich, Kai Schiemann, Stephanie Simon, Richard Schneider, Melanie Valenti, Stefan Weigt, Julian Blagg, Andree Blaukat, Trevor C Dale, Suzanne A Eccles, Stefan Hecht, Klaus Urbahns, Paul Workman, Dirk Wienke
المصدر: eLife, Vol 5 (2016)
مصطلحات موضوعية: CDK8, inhibitor, Mediator complex, Wnt, super-enhancer, Medicine, Science, Biology (General), QH301-705.5
وصف الملف: electronic resource
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4
المؤلفون: Dusica Cvetinovic Santos, Klaus Urbahns, Simone C. Zimmerli, Andreas Goutopoulos, Justin R. Potnick, Andrew Bender, Michael Meyring, Adam Shutes, Christopher Charles Victor Jones, Jared Head, Ben C. Askew, Bayard R. Huck, Ansgar Wegener, Hui Qiu, Theresa L. Johnson, Nadia Brugger, Sherer Brian A, Ngan Nguyen, Mohanraj Dhanabal, Ralf Schmidt, Roland Grenningloh, Reinaldo Jones, Richard D. Caldwell, Ariele Viacava Follis, Brian Healey, Montserrat Camps, Igor Mochalkin, Federica Morandi, Lesley Liu-Bujalski, Vikram Dutt, Brian L. Hodous, Anna Gardberg, Thomas Eichhorn
المصدر: Journal of Medicinal Chemistry. 62:7643-7655
مصطلحات موضوعية: Administration, Oral, 01 natural sciences, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Piperidines, In vivo, Drug Discovery, Agammaglobulinaemia Tyrosine Kinase, medicine, Humans, Bruton's tyrosine kinase, Epidermal growth factor receptor, Protein Kinase Inhibitors, B cell, 030304 developmental biology, 0303 health sciences, Dose-Response Relationship, Drug, Molecular Structure, biology, Drug discovery, Kinase, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Pyrimidines, medicine.anatomical_structure, Immune System Diseases, chemistry, Ibrutinib, biology.protein, Cancer research, Molecular Medicine, Tyrosine kinase
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5
المؤلفون: Shashank Kulkarni, Thomas Spangenberg, Klaus Urbahns
المصدر: ACS infectious diseases. 6(11)
مصطلحات موضوعية: 0301 basic medicine, Plasmodium, biology, 030106 microbiology, Disease, biology.organism_classification, medicine.disease, Virology, World health, Malaria, 03 medical and health sciences, Antimalarials, 030104 developmental biology, Infectious Diseases, parasitic diseases, medicine, Humans
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6
المؤلفون: Lisa, Kötzner, Bayard, Huck, Sakshi, Garg, Klaus, Urbahns
المصدر: Progress in medicinal chemistry. 59
مصطلحات موضوعية: Small Molecule Libraries, Neoplasms, Humans, Antineoplastic Agents, Amino Acids, Protein Kinase Inhibitors, Protein Kinases
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::837fac698ac6e4ffec531726af3349a8
https://pubmed.ncbi.nlm.nih.gov/32362326 -
7
المؤلفون: Clemens Kühn, Lassina Badolo, Lara Rosenberger, Klaus Urbahns, Anupam Khutia, Katrin Georgi, Carolina von Essen, Rolf W. Hartmann
المساهمون: HIPS, Helmholtz-Institut für Pharmazeutische Forschung Saarland, Universitätscampus E8.1 66123 Saarbrücken, Germany.
المصدر: Drug Metabolism and Disposition
مصطلحات موضوعية: Metabolite, Chemistry, Pharmaceutical, Pharmaceutical Science, Fractionation, Chemical Fractionation, 030226 pharmacology & pharmacy, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, X-Ray Diffraction, Liquid chromatography–mass spectrometry, Tandem Mass Spectrometry, medicine, Gemfibrozil, Animals, Humans, Chromatography, High Pressure Liquid, Pharmacology, Chromatography, biology, Molecular Structure, Drug discovery, Metabolism, biology.organism_classification, Rats, Sponge, chemistry, 030220 oncology & carcinogenesis, Microsome, Microsomes, Liver, Oxidation-Reduction, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d9f7b5847909700c43103e321c3a1ba
https://pubmed.ncbi.nlm.nih.gov/32434832 -
8
المؤلفون: Bayard R. Huck, Sakshi Garg, Lisa Kötzner, Klaus Urbahns
مصطلحات موضوعية: Oncology, medicine.medical_specialty, business.industry, Immune checkpoint inhibitors, Cancer, medicine.disease, 01 natural sciences, Small molecule, 0104 chemical sciences, Blockade, 010404 medicinal & biomolecular chemistry, Internal medicine, medicine, business, LEAPS
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f0309c749df2c83fff3e7d3758a7eab1
https://doi.org/10.1016/bs.pmch.2019.11.001 -
9
المؤلفون: Bayard R. Huck, Klaus Urbahns, Lisa Kötzner
المصدر: Angewandte Chemie (International Ed. in English)
مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, Combination therapy, Immune checkpoint inhibitors, Reviews, Antineoplastic Agents, Review, Catalysis, combination therapy, Small Molecule Libraries, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, Internal medicine, medicine, kinase inhibitors, Humans, business.industry, T-cells, Cancer, General Chemistry, medicine.disease, Small molecule, Blockade, small molecules, checkpoint inhibitor, 030104 developmental biology, Drug Design, 030220 oncology & carcinogenesis, Immunotherapy, business
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10
المؤلفون: Klaus Urbahns, Lisa Kötzner, Bayard R. Huck
المصدر: Angewandte Chemie. 130:4499-4516
مصطلحات موضوعية: 0301 basic medicine, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, business.industry, 030220 oncology & carcinogenesis, Medicine, General Medicine, business