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1دورية أكاديمية
المؤلفون: Shurtleff VW; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Layton ME; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Parish CA; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Perkins JJ; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Schreier JD; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Wang Y; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Adam GC; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Alvarez N; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey 07110, United States., Bahmanjah S; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Bahnck-Teets CM; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Boyce CW; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Burlein C; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Cabalu TD; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Campbell BT; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Carroll SS; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Chang W; Merck & Co., Inc., Rahway, New Jersey 07065, United States., de Lera Ruiz M; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Dolgov E; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey 07110, United States., Fay JF; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Fox NG; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Goh SL; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Hartingh TJ; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Hurzy DM; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Kelly MJ 3rd; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Klein DJ; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Klingler FM; MSD (U.K.) Limited, London EC2M 6UR, U.K., Krishnamurthy H; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Kudalkar S; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Mayhood TW; Merck & Co., Inc., Rahway, New Jersey 07065, United States., McKenna PM; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Murray EM; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Nahas D; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Nawrat CC; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Park S; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey 07110, United States., Qian D; Viva Biotech Ltd., Shanghai 201318, China., Roecker AJ; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Sharma V; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey 07110, United States., Shipe WD; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Su J; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Taggart RV; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Truong Q; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Wu Y; Viva Biotech Ltd., Shanghai 201318, China., Zhou X; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Zhuang N; Viva Biotech Ltd., Shanghai 201318, China., Perlin DS; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey 07110, United States., Olsen DB; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Howe JA; Merck & Co., Inc., West Point, Pennsylvania 19486, United States., McCauley JA; Merck & Co., Inc., West Point, Pennsylvania 19486, United States.
المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Mar 14; Vol. 67 (5), pp. 3935-3958. Date of Electronic Publication: 2024 Feb 16.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
مواضيع طبية MeSH: Glutamine*/chemistry , COVID-19*, Humans ; SARS-CoV-2 ; Cysteine Endopeptidases/chemistry ; Inventions ; Protease Inhibitors/pharmacology ; Amides ; Antiviral Agents/pharmacology ; Antiviral Agents/chemistry
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2دورية أكاديمية
المؤلفون: Gehringer M; Institute of Pharmaceutical Sciences, Pharmaceutical/Medicinal Chemistry Department, University of Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany., Pape F; NUVISAN Innovation Campus Berlin, NUVISAN ICB GmbH, Muellerstraße 178, 13353, Berlin, Germany., Méndez M; Sanofi R&D, Integrated Drug Discovery, Industriepark Höchst, Bldg. G838, 65926, Frankfurt am Main, Germany., Barbie P; Bayer AG, R&D, Pharmaceuticals, Laboratory IV, Bldg. S106, 231, 13342, Berlin, Germany., Unzue Lopez A; Merck Healthcare KGaA, Frankfurter Straße 250, 64293, Darmstadt, Germany., Lefranc J; Merck Healthcare KGaA, Frankfurter Straße 250, 64293, Darmstadt, Germany., Klingler FM; Isomorphic Labs Ltd., 100 New Bridge Street, London, EC4 V 6JA, UK., Hessler G; Sanofi R&D, Integrated Drug Discovery, Industriepark Höchst, Bldg. G877, 65926, Frankfurt am Main, Germany., Langer T; Department of Pharmaceutical Sciences, University of Vienna, Josef-Holaubek-Platz 2, 1090, Vienna, Austria., Diamanti E; Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy., Schiedel M; Institute of Medicinal and Pharmaceutical Chemistry, Technische Universität Braunschweig, Beethovenstraße 55, 38106, Braunschweig, Germany.
المصدر: ChemMedChem [ChemMedChem] 2023 Oct 04; Vol. 18 (19), pp. e202300344. Date of Electronic Publication: 2023 Jul 24.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE
مواضيع طبية MeSH: Chemistry, Pharmaceutical* , Pandemics*, Humans ; Austria
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3دورية أكاديمية
المؤلفون: Diamanti E; HIPS - Helmholtz-Institut für Pharmazeutische Forschung Saarland, Campus E8 1, 66123, Saarbrücken, Germany., Méndez M; Sanofi R&D, Integrated Drug Discovery, Industriepark Höchst, Blg. G838, 65926, Frankfurt am Main, Germany., Ross T; Merck Healthcare KGaA, Frankfurter Straße 250, 64293, Darmstadt, Germany., Kuttruff CA; Boehringer Ingelheim International GmbH, Birkendorfer Straße 65, 88397, Biberach an der Riss, Germany., Lefranc J; Merck Healthcare KGaA, Frankfurter Straße 250, 64293, Darmstadt, Germany., Klingler FM; MSD R&D Innovation Centre, 120 Moorgate, EC2 M 6UR, London, UK., von Nussbaum F; NUVISAN Innovation Campus Berlin, NUVISAN ICB GmbH, Muellerstr. 178, 13353, Berlin, Germany., Jung M; Institute of Pharmaceutical Sciences, Albert-Ludwigs-Universität Freiburg, Albertstraße 25, 79104, Freiburg im Breisgau, Germany., Gehringer M; University of Tübingen, Institute of Pharmaceutical Sciences, Pharmaceutical/Medicinal Chemistry Department, Auf der Morgenstelle 8, 72076, Tübingen, Germany.
المصدر: ChemMedChem [ChemMedChem] 2022 Nov 04; Vol. 17 (21), pp. e202200419. Date of Electronic Publication: 2022 Oct 05.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE
مواضيع طبية MeSH: Chemistry, Pharmaceutical*, Humans ; Germany
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4دورية أكاديمية
المؤلفون: Beroza P; Discovery Chemistry, Genentech, South San Francisco, USA. berozap@gene.com., Crawford JJ; Discovery Chemistry, Genentech, South San Francisco, USA., Ganichkin O; Proteros Biostructures GmbH, Planegg, Germany., Gendelev L; Discovery Chemistry, Genentech, South San Francisco, USA., Harris SF; Structural Biology, Genentech, South San Francisco, USA., Klein R; BioSolveIT GmbH, St. Augustin, Germany., Miu A; Biochemical and Cellular Pharmacology, Genentech, South San Francisco, USA., Steinbacher S; Proteros Biostructures GmbH, Planegg, Germany., Klingler FM; BioSolveIT GmbH, St. Augustin, Germany.; MSD, London, England., Lemmen C; BioSolveIT GmbH, St. Augustin, Germany.
المصدر: Nature communications [Nat Commun] 2022 Oct 28; Vol. 13 (1), pp. 6447. Date of Electronic Publication: 2022 Oct 28.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
مواضيع طبية MeSH: Proteins* , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/chemistry, Molecular Docking Simulation ; Ligands ; Protein Binding
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5دورية أكاديمية
المؤلفون: Mamriev D; Cell Death and Cancer Research Laboratory, Department of Human Biology and Medical Sciences, University of Haifa, Haifa, 31905, Israel.; The Laboratory of Tumor Dormancy and Metastasis, Department of Human Biology and Medical Sciences, University of Haifa, Haifa, 31905, Israel., Abbas R; Cell Death and Cancer Research Laboratory, Department of Human Biology and Medical Sciences, University of Haifa, Haifa, 31905, Israel., Klingler FM; BioSolveIT GmbH, Sankt Augustin, Germany., Kagan J; Cell Death and Cancer Research Laboratory, Department of Human Biology and Medical Sciences, University of Haifa, Haifa, 31905, Israel., Kfir N; Cell Death and Cancer Research Laboratory, Department of Human Biology and Medical Sciences, University of Haifa, Haifa, 31905, Israel., Donald A; BioSolveIT GmbH, Sankt Augustin, Germany., Weidenfeld K; The Laboratory of Tumor Dormancy and Metastasis, Department of Human Biology and Medical Sciences, University of Haifa, Haifa, 31905, Israel., Sheppard DW; Sheppard R&D Consultancy Ltd, Suffolk, United Kingdom., Barkan D; The Laboratory of Tumor Dormancy and Metastasis, Department of Human Biology and Medical Sciences, University of Haifa, Haifa, 31905, Israel., Larisch S; Cell Death and Cancer Research Laboratory, Department of Human Biology and Medical Sciences, University of Haifa, Haifa, 31905, Israel. saritlarisch@gmail.com.
المصدر: Cell death & disease [Cell Death Dis] 2020 Jun 25; Vol. 11 (6), pp. 483. Date of Electronic Publication: 2020 Jun 25.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
مواضيع طبية MeSH: Apoptosis*/drug effects, Proteolysis/*drug effects , Septins/*metabolism , Small Molecule Libraries/*pharmacology , X-Linked Inhibitor of Apoptosis Protein/*metabolism, Binding Sites ; Caspases/metabolism ; Cell Death/drug effects ; Cell Line ; Humans ; Inhibitory Concentration 50 ; Proteasome Endopeptidase Complex/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Small Molecule Libraries/chemistry
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6دورية أكاديمية
المؤلفون: Kramer JS; Institute of Pharmaceutical Chemistry , Goethe-University Frankfurt , Max-von-Laue-Strasse 9 , 60438 Frankfurt am Main , Germany., Woltersdorf S; Institute of Pharmaceutical Chemistry , Goethe-University Frankfurt , Max-von-Laue-Strasse 9 , 60438 Frankfurt am Main , Germany., Duflot T; Laboratory of Pharmacokinetics, Toxicology and Pharmacogenetics , Rouen University Hospital , 76000 Rouen , France.; Normandie Université, UNIROUEN, INSERM U1096 , 1 rue de Germont , 76000 Rouen , France., Hiesinger K; Institute of Pharmaceutical Chemistry , Goethe-University Frankfurt , Max-von-Laue-Strasse 9 , 60438 Frankfurt am Main , Germany., Lillich FF; Institute of Pharmaceutical Chemistry , Goethe-University Frankfurt , Max-von-Laue-Strasse 9 , 60438 Frankfurt am Main , Germany., Knöll F; Institute of Pharmaceutical Chemistry , Goethe-University Frankfurt , Max-von-Laue-Strasse 9 , 60438 Frankfurt am Main , Germany., Wittmann SK; Institute of Pharmaceutical Chemistry , Goethe-University Frankfurt , Max-von-Laue-Strasse 9 , 60438 Frankfurt am Main , Germany., Klingler FM; Institute of Pharmaceutical Chemistry , Goethe-University Frankfurt , Max-von-Laue-Strasse 9 , 60438 Frankfurt am Main , Germany., Brunst S; Institute of Pharmaceutical Chemistry , Goethe-University Frankfurt , Max-von-Laue-Strasse 9 , 60438 Frankfurt am Main , Germany., Chaikuad A; Institute of Pharmaceutical Chemistry , Goethe-University Frankfurt , Max-von-Laue-Strasse 9 , 60438 Frankfurt am Main , Germany.; Structural Genomics Consortium, Buchmann Institute for Life Sciences , Goethe-University Frankfurt , Max-von-Laue-Strasse 15 , 60438 Frankfurt am Main , Germany., Morisseau C; Department of Entomology and Nematology and UC Davis Comprehensive Cancer Center , University of California Davis , Davis , California 95616 , United States., Hammock BD; Department of Entomology and Nematology and UC Davis Comprehensive Cancer Center , University of California Davis , Davis , California 95616 , United States., Buccellati C; Department of Pharmacological and Biomolecular Sciences , University of Milan , Via Balzaretti 9 , 20133 Milan , Italy., Sala A; Department of Pharmacological and Biomolecular Sciences , University of Milan , Via Balzaretti 9 , 20133 Milan , Italy., Rovati GE; Department of Pharmacological and Biomolecular Sciences , University of Milan , Via Balzaretti 9 , 20133 Milan , Italy., Leuillier M; Normandie Université, UNIROUEN, INSERM U1096 , 1 rue de Germont , 76000 Rouen , France., Fraineau S; Normandie Université, UNIROUEN, INSERM U1096 , 1 rue de Germont , 76000 Rouen , France., Rondeaux J; Normandie Université, UNIROUEN, INSERM U1096 , 1 rue de Germont , 76000 Rouen , France., Hernandez-Olmos V; Institute of Pharmaceutical Chemistry , Goethe-University Frankfurt , Max-von-Laue-Strasse 9 , 60438 Frankfurt am Main , Germany.; Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Branch for Translational Medicine and Pharmacology TMP , Theodor-Stern-Kai 7 , 60596 Frankfurt am Main , Germany., Heering J; Institute of Pharmaceutical Chemistry , Goethe-University Frankfurt , Max-von-Laue-Strasse 9 , 60438 Frankfurt am Main , Germany.; Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Branch for Translational Medicine and Pharmacology TMP , Theodor-Stern-Kai 7 , 60596 Frankfurt am Main , Germany., Merk D; Institute of Pharmaceutical Chemistry , Goethe-University Frankfurt , Max-von-Laue-Strasse 9 , 60438 Frankfurt am Main , Germany., Pogoryelov D; Institute of Biochemistry , Goethe-University Frankfurt , Max-von-Laue-Strasse 9 , 60438 Frankfurt am Main , Germany., Steinhilber D; Institute of Pharmaceutical Chemistry , Goethe-University Frankfurt , Max-von-Laue-Strasse 9 , 60438 Frankfurt am Main , Germany., Knapp S; Institute of Pharmaceutical Chemistry , Goethe-University Frankfurt , Max-von-Laue-Strasse 9 , 60438 Frankfurt am Main , Germany.; Laboratory of Pharmacokinetics, Toxicology and Pharmacogenetics , Rouen University Hospital , 76000 Rouen , France., Bellien J; Normandie Université, UNIROUEN, INSERM U1096 , 1 rue de Germont , 76000 Rouen , France.; Department of Clinical Pharmacology , Rouen University Hospital , 76000 Rouen , France., Proschak E; Institute of Pharmaceutical Chemistry , Goethe-University Frankfurt , Max-von-Laue-Strasse 9 , 60438 Frankfurt am Main , Germany.
المصدر: Journal of medicinal chemistry [J Med Chem] 2019 Sep 26; Vol. 62 (18), pp. 8443-8460. Date of Electronic Publication: 2019 Sep 17.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
مواضيع طبية MeSH: Enzyme Inhibitors/*chemistry , Epoxide Hydrolases/*antagonists & inhibitors , Epoxide Hydrolases/*chemistry, Animals ; Binding Sites ; Catalytic Domain ; Drug Design ; Humans ; Ligands ; Male ; Oxazoles/chemistry ; Phosphoric Monoester Hydrolases/chemistry ; Rats ; Rats, Sprague-Dawley ; Structure-Activity Relationship ; Temperature
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7دورية أكاديمية
المؤلفون: Klingler FM; BioSolveIT GmbH, An der Ziegelei 79, 53757 Sankt Augustin, Germany. klingler@biosolveit.de., Gastreich M; BioSolveIT GmbH, An der Ziegelei 79, 53757 Sankt Augustin, Germany., Grygorenko OO; Enamine Ltd., Chervonotkatska Street 78, 02094 Kyiv, Ukraine.; Taras Shevchenko National University of Kyiv, Volodymyrska Street 60, 01601 Kyiv, Ukraine., Savych O; Enamine Ltd., Chervonotkatska Street 78, 02094 Kyiv, Ukraine., Borysko P; Bienta/Enamine Ltd., Chervonotkatska Street 78, 02094 Kyiv, Ukraine., Griniukova A; Bienta/Enamine Ltd., Chervonotkatska Street 78, 02094 Kyiv, Ukraine., Gubina KE; Taras Shevchenko National University of Kyiv, Volodymyrska Street 60, 01601 Kyiv, Ukraine., Lemmen C; BioSolveIT GmbH, An der Ziegelei 79, 53757 Sankt Augustin, Germany., Moroz YS; Taras Shevchenko National University of Kyiv, Volodymyrska Street 60, 01601 Kyiv, Ukraine. ysmoroz@gmail.com.; Chemspace, Ilukstes iela 38-5, LV-1082 Riga, Latvia. ysmoroz@gmail.com.
المصدر: Molecules (Basel, Switzerland) [Molecules] 2019 Aug 26; Vol. 24 (17). Date of Electronic Publication: 2019 Aug 26.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE
مواضيع طبية MeSH: Computational Biology/*methods , Small Molecule Libraries/*pharmacology , Transcription Factors/*chemistry , Transcription Factors/*metabolism, Binding Sites ; Databases, Chemical ; Drug Evaluation, Preclinical/methods ; High-Throughput Screening Assays ; Humans ; Inhibitory Concentration 50 ; Molecular Docking Simulation ; Molecular Structure ; Protein Binding ; Small Molecule Libraries/chemistry ; Structure-Activity Relationship
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8دورية أكاديمية
المؤلفون: Büttner D, Kramer JS, Klingler FM, Wittmann SK, Hartmann MR, Kurz CG, Kohnhäuser D, Weizel L, Brüggerhoff A, Frank D; Institute of Medical Microbiology and Infection Control , Goethe University Hospital , Paul-Ehrlich-Straße 40 , 60596 Frankfurt , Germany., Steinhilber D, Wichelhaus TA; Institute of Medical Microbiology and Infection Control , Goethe University Hospital , Paul-Ehrlich-Straße 40 , 60596 Frankfurt , Germany., Pogoryelov D, Proschak E
المصدر: ACS infectious diseases [ACS Infect Dis] 2018 Mar 09; Vol. 4 (3), pp. 360-372. Date of Electronic Publication: 2017 Dec 12.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE
مواضيع طبية MeSH: Drug Discovery/*methods , Sulfhydryl Compounds/*isolation & purification , Sulfhydryl Compounds/*pharmacology , beta-Lactamase Inhibitors/*isolation & purification , beta-Lactamase Inhibitors/*pharmacology, Sulfhydryl Compounds/chemical synthesis ; beta-Lactam Resistance/drug effects ; beta-Lactamase Inhibitors/chemical synthesis
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9دورية أكاديمية
المؤلفون: Klingler FM; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Frankfurt, Germany., Wolf M; Fraunhofer Institute for Molecular Biology and Environmental Ecology ScreeningPort, Hamburg, Germany., Wittmann S; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Frankfurt, Germany., Gribbon P; Fraunhofer Institute for Molecular Biology and Environmental Ecology ScreeningPort, Hamburg, Germany., Proschak E; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Frankfurt, Germany proschak@pharmchem.uni-frankfurt.de.
المصدر: Journal of biomolecular screening [J Biomol Screen] 2016 Aug; Vol. 21 (7), pp. 689-94. Date of Electronic Publication: 2016 Mar 23.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Sage Publications Country of Publication: United States NLM ID: 9612112 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-454X (Electronic) Linking ISSN: 10870571 NLM ISO Abbreviation: J Biomol Screen Subsets: MEDLINE
مواضيع طبية MeSH: Enzyme Inhibitors/*isolation & purification , Epoxide Hydrolases/*antagonists & inhibitors , High-Throughput Screening Assays/*methods , Phosphoric Monoester Hydrolases/*antagonists & inhibitors, Animals ; Catalytic Domain/genetics ; Enzyme Inhibitors/pharmacology ; Escherichia coli/genetics ; Gene Expression Regulation, Enzymologic/genetics ; Humans ; Mice ; Phosphoric Monoester Hydrolases/genetics ; Solubility
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10دورية أكاديمية
المؤلفون: Klingler FM; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Straße 9, 60438 Frankfurt, Germany., Moser D; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Straße 9, 60438 Frankfurt, Germany., Büttner D; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Straße 9, 60438 Frankfurt, Germany., Wichelhaus TA; Institute of Medical Microbiology and Infection Control, Goethe University, Paul-Ehrlich-Straße 40, 60596 Frankfurt, Germany., Löhr F; Institute of Biophysical Chemistry, Goethe University Frankfurt, Max-von-Laue-Straße 9, 60438 Frankfurt, Germany., Dötsch V; Institute of Biophysical Chemistry, Goethe University Frankfurt, Max-von-Laue-Straße 9, 60438 Frankfurt, Germany., Proschak E; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Straße 9, 60438 Frankfurt, Germany. Electronic address: proschak@pharmchem.uni-frankfurt.de.
المصدر: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2015 Nov 15; Vol. 25 (22), pp. 5243-6. Date of Electronic Publication: 2015 Sep 28.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE