يعرض 1 - 10 نتائج من 285 نتيجة بحث عن '"Knowles, TPJ"', وقت الاستعلام: 0.92s تنقيح النتائج
  1. 1
    دورية أكاديمية
    A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers

    المؤلفون: Cohen, SIA, Arosio, P, Presto, J, Kurudenkandy, FR, Biverstal, H, Dolfe, L, Dunning, C, Yang, XT, Frohm, B, Vendruscolo, M, Johansson, J, Dobson, CM, Fisahn, A, Knowles, TPJ, Linse, S

    المصدر: Nature structural & molecular biology. 22(3):207-213

    مصطلحات موضوعية: Medicin och hälsovetenskap

    URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:130873608

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  2. 2
    دورية أكاديمية
    Kinetic analysis reveals the diversity of microscopic mechanisms through which molecular chaperones suppress amyloid formation

    المؤلفون: Arosio, P, Michaels, TCT, Linse, S, Mansson, C, Emanuelsson, C, Presto, J, Johansson, J, Vendruscolo, M, Dobson, CM, Knowles, TPJ

    المصدر: Nature communications. 7:10948

    مصطلحات موضوعية: Medicin och hälsovetenskap

    URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:133216065

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  3. 3
    Structure-specific amyloid precipitation in biofluids

    المؤلفون: Rodrigues, M, Bhattacharjee, P, Brinkmalm, A, Do, DT, Pearson, CM, De, S, Ponjavic, A, Varela, JA, Kulenkampff, K, Baudrexel, I, Emin, D, Ruggeri, FS, Lee, JE, Carr, AR, Knowles, TPJ, Zetterberg, H, Snaddon, TN, Gandhi, S, Lee, SF, Klenerman, D

    المساهمون: European Research Council, University of St Andrews. School of Physics and Astronomy, University of St Andrews. Centre for Biophotonics, University of St Andrews. Institute of Behavioural and Neural Sciences, Rodrigues, M [0000-0001-6364-7125], Bhattacharjee, P [0000-0002-1116-5877], Do, DT [0000-0002-5717-4285], De, S [0000-0003-1675-0773], Ponjavic, A [0000-0002-7561-1127], Varela, JA [0000-0003-1901-1378], Baudrexel, I [0000-0002-3422-8340], Ruggeri, FS [0000-0002-1232-1907], Knowles, TPJ [0000-0002-7879-0140], Snaddon, TN [0000-0003-1119-0332], Gandhi, S [0000-0003-4395-2661], Lee, SF [0000-0003-4492-5139], Klenerman, D [0000-0001-7116-6954], Apollo - University of Cambridge Repository

    المصدر: Nature Chemistry, 14(9), 1045-1053
    Nature Chemistry 14 (2022) 9

    مصطلحات موضوعية: MCC, Amyloid, Bodily Secretions, Amyloid beta-Peptides, General Chemical Engineering, education, Organic Chemistry, DAS, General Chemistry, QD Chemistry, Organische Chemie, AC, Protein Aggregates, SDG 3 - Good Health and Well-being, RC0321, Life Science, Humans, QD, RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry, Physical Chemistry and Soft Matter

    وصف الملف: application/octet-stream; application/pdf; text/html

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44466f17b9de5a1796608ad8f28a5775
    https://research.wur.nl/en/publications/structure-specific-amyloid-precipitation-in-biofluids

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  4. 4
    The binding of the small heat-shock protein alpha B-crystallin to fibrils of alpha-synuclein is driven by entropic forces

    المؤلفون: Scheidt, T, Carozza, JA, Kolbe, CC, Aprile, FA, Tkachenko, O, Bellaiche, MMJ, Meisl, G, Peter, QAE, Herling, TW, Ness, S, Castellana-Cruz, M, Benesch, JLP, Vendruscolo, M, Dobson, CM, Arosio, P, Knowles, TPJ

    المساهمون: Medical Research Council (MRC), Alzheimer's Society

    مصطلحات موضوعية: DISORDER, Science & Technology, ELONGATION, microfluidics, aggregation, INHIBITION, IN-VITRO, Multidisciplinary Sciences, thermodynamic, MOLECULAR CHAPERONES, kinetic analysis, Science & Technology - Other Topics, chaperones, CYCLE

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1032::77ff3a64c145a5558da41bc6427d831a
    http://hdl.handle.net/10044/1/92310

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  5. 5
    Microfluidic Antibody Affinity Profiling for In-Solution Characterisation of Alloantibody - HLA Interactions in Human Serum

    المؤلفون: Kosmoliaptsis, Catherine K. Xu, Georg Meisl, Tom Scheidt, Michele T.M. Hu, Matthias Schneider, Priddey Aj, Knowles Tpj, Christopher M. Dobson, Devenish Sra

    مصطلحات موضوعية: biology, Chemistry, Microfluidics, Antibody affinity, Human leukocyte antigen, medicine.disease_cause, Autoimmunity, Titer, Biochemistry, Allograft rejection, medicine, biology.protein, Avidity, Antibody

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ea3179217026896c48db6e87bba4362f
    https://doi.org/10.1101/2020.09.14.296442

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  6. 6
    Clathrin-Inspired Coating and Stabilization of Liposomes by DNA Self-Assembly

    المؤلفون: Diana Sobota, Hernandez Ainsa S, Javier García-Nafría, Kevin N. Baumann, Luca Piantanida, Knowles Tpj, Kislon Voïtchovsky

    مصطلحات موضوعية: Liposome, Materials science, biology, Cryo-electron microscopy, Nanotechnology, engineering.material, Clathrin, Coating, Dynamic light scattering, DNA nanotechnology, biology.protein, engineering, Self-assembly, Nanocarriers

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77bb42f9d35d07bab576df51b21ba62d
    https://doi.org/10.26434/chemrxiv.8859017.v1

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  7. 7
    Phase Separation of FUS is Modulated by Methylation State of Cation-π Interactions and Interaction with TNPO1

    المؤلفون: St George-Hyslop, PH, Qamar, S, Wang, Guozhen, Randle, SJ, Ruggeri, Francesco Simone, Varela, Juan, Kaminski, CF, Kaminski, GS, Vendruscolo, M, Knowles, TPJ, Klenerman, D, Holt, CE, Lin, Q, Meadows, William

    المساهمون: St George-Hyslop, Peter [0000-0003-0796-7209], Varela, Juan [0000-0003-1901-1378], Kaminski, Clemens [0000-0002-5194-0962], Kaminski Schierle, Gabriele [0000-0002-1843-2202], Vendruscolo, Michele [0000-0002-3616-1610], Knowles, Tuomas [0000-0002-7879-0140], Klenerman, David [0000-0001-7116-6954], Holt, Christine [0000-0003-2829-121X], Lin, Qiaojin [0000-0002-2669-6478], Apollo - University of Cambridge Repository

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e149434a94dcae6a5baaf8fc21f00548

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  8. 8
    Multistep Inhibition of α‑Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine

    المؤلفون: Perni, M, Flagmeier, P, Limbocker, R, Cascella, R, Aprile, Fa, Galvagnion, C, Heller, Gt, Meisl, G, Chen, Sw, Kumita, Jr, Challa, Pk, Kirkegaard, Jb, Cohen, Sia, Mannini, B, Barbut, D, Nollen, Eaa, Cecchi, C, Cremades, N, Knowles, Tpj, Chiti, F, Zasloff, M, Vendruscolo, M, Dobson, Cm

    مصطلحات موضوعية: α‑Synuclein aggregation, Trodusquemine

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______310::643934268520e9e7d9e32fb2a8239319
    http://hdl.handle.net/2158/1132660

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  9. 9
    Secondary nucleation of monomers on fibril surface dominates $\alpha$-synuclein aggregation and provides autocatalytic amyloid amplification

    المؤلفون: Gaspar, R, Meisl, G, Buell, AK, Young, L, Kaminski, CF, Knowles, TPJ, Sparr, E, Linse, S

    المساهمون: Meisl, Georg [0000-0002-6562-7715], Kaminski, Clemens [0000-0002-5194-0962], Knowles, Tuomas [0000-0002-7879-0140], Apollo - University of Cambridge Repository

    مصطلحات موضوعية: Amyloid, Kinetics, Surface Properties, Biocatalysis, alpha-Synuclein, Protein Multimerization, Protein Structure, Secondary, Molecular Imaging

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3318417307ef9cdf4d115f43dda19ad
    https://www.repository.cam.ac.uk/handle/1810/263245

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  10. 10
    Electrostatically-guided inhibition of Curli amyloid nucleation by the CsgC-like family of chaperones

    المؤلفون: Taylor, JD, Hawthorne, WJ, Lo, J, Dear, A, Jain, N, Meisl, G, Andreasen, M, Fletcher, C, Koch, M, Darvill, N, Scull, N, Escalera-Maurer, A, Sefer, L, Wenman, R, Lambert, S, Jean, J, Xu, Y, Turner, B, Kazarian, SG, Chapman, MR, Bubeck, D, De Simone, A, Knowles, TPJ, Matthews, SJ

    المساهمون: Taylor, J. D., Hawthorne, W. J., Lo, J., Dear, A., Jain, N., Meisl, G., Andreasen, M., Fletcher, C., Koch, M., Darvill, N., Scull, N., Escalera-Maurer, A., Sefer, L., Wenman, R., Lambert, S., Jean, J., Xu, Y., Turner, B., Kazarian, S. G., Chapman, M. R., Bubeck, D., De Simone, A., Knowles, T. P. J., Matthews, S. J., Medical Research Council (MRC), Wellcome Trust

    المصدر: Scientific Reports

    مصطلحات موضوعية: Amyloid, Kinetics, Protein Folding, Protein Conformation, Escherichia coli Proteins, mental disorders, Osmolar Concentration, Static Electricity, Active Transport, Cell Nucleus, Article, Molecular Chaperones, Protein Binding

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6f634b520bd6ec3bd0b90a6367d84523

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