المؤلفون: Duarte, D, Amarteifio, S, Ang, H, Kong, IY, Ruivo, N, Pruessner, G, Hawkins, ED, Lo Celso, C

المساهمون: Human Frontier Science Program, Bloodwise, Commission of the European Communities, European Hematology Association, Biotechnology and Biological Sciences Research Council (BBSRC), Blood Cancer UK, Cancer Research UK

مصطلحات موضوعية: Receptors, CXCR4, Intravital Microscopy, Acute myeloid leukemia cells, Immunology, INHIBITION, PROGENITOR, chemokines, Antineoplastic Agents, 0601 Biochemistry and Cell Biology, CHEMOSENSITIZATION, PLUS G-CSF, Mice, Bone Marrow, Cell Movement, Heterocyclic Compounds, hemic and lymphatic diseases, Cell Line, Tumor, Tumor Microenvironment, Animals, lymphoblastic leukemia, neoplasms, CXCR4, Science & Technology, Microscopy, Confocal, Cell Biology, CHEMOTHERAPY, Chemokine CXCL12, Leukemia, Myeloid, Acute, Microscopy, Fluorescence, Multiphoton, Drug Resistance, Neoplasm, 1107 Immunology, intravital imaging, MOBILIZATION, Life Sciences & Biomedicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1032::2456beb355e8315c70f5161a5c9f5b8a
http://hdl.handle.net/10044/1/66316

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المؤلفون: Chiou S; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia., Al-Ani AH; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia.; Royal Melbourne Hospital, Parkville, Australia., Pan Y; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia., Patel KM; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia., Kong IY; Pediatric Hematology/Oncology, Weill Cornell Medical College, New York, USA., Whitehead LW; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia., Light A; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia., Young SN; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia., Barrios M; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia., Sargeant C; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia., Rajasekhar P; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia., Zhu L; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia., Hempel A; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia., Lin A; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia., Rickard JA; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; Austin Hospital, Heidelberg, Australia., Hall C; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia., Gangatirkar P; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia., Yip RK; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia., Cawthorne W; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia., Jacobsen AV; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia., Horne CR; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia., Martin KR; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia., Ioannidis LJ; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia., Hansen DS; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia.; Monash Biomedicine Discovery Institute, Department of Microbiology, Monash University, Clayton, Australia., Day J; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia.; Royal Melbourne Hospital, Parkville, Australia., Wicks IP; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia., Law C; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia., Ritchie ME; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia., Bowden R; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia., Hildebrand JM; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia., O'Reilly LA; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia., Silke J; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia., Giulino-Roth L; Pediatric Hematology/Oncology, Weill Cornell Medical College, New York, USA., Tsui E; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia., Rogers KL; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia., Hawkins ED; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia., Christensen B; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; University of Melbourne, Parkville, Australia.; Royal Melbourne Hospital, Parkville, Australia., Murphy JM; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia. jamesm@wehi.edu.au.; University of Melbourne, Parkville, Australia. jamesm@wehi.edu.au.; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia. jamesm@wehi.edu.au., Samson AL; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia. samson.a@wehi.edu.au.; University of Melbourne, Parkville, Australia. samson.a@wehi.edu.au.

المصدر: EMBO molecular medicine [EMBO Mol Med] 2024 Jul; Vol. 16 (7), pp. 1717-1749. Date of Electronic Publication: 2024 May 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE

مواضيع طبية MeSH: Necroptosis* , Receptor-Interacting Protein Serine-Threonine Kinases*/metabolism , Receptor-Interacting Protein Serine-Threonine Kinases*/genetics , Immunohistochemistry*/methods, Animals ; Humans ; Mice ; Protein Kinases/metabolism ; Protein Kinases/genetics ; Caspase 8/metabolism ; Signal Transduction ; Mice, Inbred C57BL

المؤلفون: Kong IY; Weill Cornell Medical College, New York, NY, United States., Giulino-Roth L; Weill Cornell Medical College, New York, NY, United States.

المصدر: Frontiers in immunology [Front Immunol] 2024 Feb 23; Vol. 15, pp. 1342455. Date of Electronic Publication: 2024 Feb 23 (Print Publication: 2024).

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Epstein-Barr Virus Infections*/complications , Burkitt Lymphoma*/pathology , Lymphoma, Large B-Cell, Diffuse*/pathology , Latent Infection*, Humans ; Herpesvirus 4, Human ; Virus Latency ; Viral Proteins/genetics

المؤلفون: Goh W; The Walter and Eliza Hall Institute of Medical Research. Department of Medical Biology, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Melbourne, Victoria, Australia., Sudholz H; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia., Foroutan M; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.; oNKo-Innate Pty Ltd, Melbourne, Victoria, Australia., Scheer S; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.; Department of Infection and Immunity, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg., Pfefferle A; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.; oNKo-Innate Pty Ltd, Melbourne, Victoria, Australia., Delconte RB; The Walter and Eliza Hall Institute of Medical Research. Department of Medical Biology, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Melbourne, Victoria, Australia.; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Meng X; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia., Shen Z; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia., Hennessey R; The Walter and Eliza Hall Institute of Medical Research. Department of Medical Biology, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Melbourne, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia., Kong IY; The Walter and Eliza Hall Institute of Medical Research. Department of Medical Biology, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Melbourne, Victoria, Australia., Schuster IS; Infection and Immunity Program and Department of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.; Centre for Experimental Immunology, Lions Eye Institute, Nedlands, Western Australia, Australia., Andoniou CE; Infection and Immunity Program and Department of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.; Centre for Experimental Immunology, Lions Eye Institute, Nedlands, Western Australia, Australia., Davis MJ; The Walter and Eliza Hall Institute of Medical Research. Department of Medical Biology, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Melbourne, Victoria, Australia.; Frazer Institute, University of Queensland, Woolloongabba, Queensland, Australia.; The South Australian immunoGENomics Cancer Institute (SAiGENCI), Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia., Hediyeh-Zadeh S; The Walter and Eliza Hall Institute of Medical Research. Department of Medical Biology, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Melbourne, Victoria, Australia., Souza-Fonseca-Guimaraes F; Frazer Institute, University of Queensland, Woolloongabba, Queensland, Australia., Parish IA; Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia., Beavis P; Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia., Thiele D; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia., Chopin M; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia., Degli-Esposti MA; Infection and Immunity Program and Department of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.; Centre for Experimental Immunology, Lions Eye Institute, Nedlands, Western Australia, Australia., Cursons J; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.; oNKo-Innate Pty Ltd, Melbourne, Victoria, Australia., Kallies A; Department of Microbiology & Immunology, Faculty of Medicine, Dentistry and Health Sciences & Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia., Rautela J; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.; oNKo-Innate Pty Ltd, Melbourne, Victoria, Australia., Nutt SL; The Walter and Eliza Hall Institute of Medical Research. Department of Medical Biology, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Melbourne, Victoria, Australia., Huntington ND; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia. nicholas.huntington@monash.edu.; oNKo-Innate Pty Ltd, Melbourne, Victoria, Australia. nicholas.huntington@monash.edu.

المصدر: Nature immunology [Nat Immunol] 2024 Feb; Vol. 25 (2), pp. 240-255. Date of Electronic Publication: 2024 Jan 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Transcription Factor AP-1*/genetics , Killer Cells, Natural*/metabolism, Receptors, Interleukin-15 ; Ikaros Transcription Factor/genetics ; Ikaros Transcription Factor/metabolism

المؤلفون: Trezise S; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia.; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Harvard University, Boston, MA, United States., Kong IY; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia.; Department of Pediatrics, Division of Pediatric Hematology/Oncology, Weill Cornell Medicine, New York, NY, United States., Hawkins ED; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia., Herold MJ; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia., Willis SN; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia., Nutt SL; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia.

المصدر: Frontiers in immunology [Front Immunol] 2023 Feb 13; Vol. 14, pp. 1089243. Date of Electronic Publication: 2023 Feb 13 (Print Publication: 2023).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Endoplasmic Reticulum-Associated Degradation* , Secretory Pathway*, Antibodies ; B-Lymphocytes ; Immunity, Humoral

المؤلفون: Kong IY; Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, 3010, VIC, Australia., Trezise S; Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, 3010, VIC, Australia., Light A; Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, 3010, VIC, Australia., Todorovski I; Peter MacCallum Cancer Centre, Melbourne, 3000, VIC, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia., Arnau GM; Peter MacCallum Cancer Centre, Melbourne, 3000, VIC, Australia., Gadipally S; Peter MacCallum Cancer Centre, Melbourne, 3000, VIC, Australia., Yoannidis D; Peter MacCallum Cancer Centre, Melbourne, 3000, VIC, Australia., Simpson KJ; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia.; Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Dong X; Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, 3010, VIC, Australia., Whitehead L; Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, 3010, VIC, Australia., Tempany JC; Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, 3010, VIC, Australia., Farchione AJ; Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, 3010, VIC, Australia., Sheikh AA; Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, VIC, Australia., Groom JR; Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, 3010, VIC, Australia., Rogers KL; Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, 3010, VIC, Australia., Herold MJ; Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, 3010, VIC, Australia., Bryant VL; Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, 3010, VIC, Australia., Ritchie ME; Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, 3010, VIC, Australia., Willis SN; Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, 3010, VIC, Australia., Johnstone RW; Peter MacCallum Cancer Centre, Melbourne, 3000, VIC, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia., Hodgkin PD; Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, 3010, VIC, Australia., Nutt SL; Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, 3010, VIC, Australia., Vervoort SJ; Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, VIC, Australia. vervoort.s@wehi.edu.au.; Department of Medical Biology, The University of Melbourne, Parkville, 3010, VIC, Australia. vervoort.s@wehi.edu.au.; Peter MacCallum Cancer Centre, Melbourne, 3000, VIC, Australia. vervoort.s@wehi.edu.au.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia. vervoort.s@wehi.edu.au., Hawkins ED; Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, VIC, Australia. Hawkins.e@wehi.edu.au.; Department of Medical Biology, The University of Melbourne, Parkville, 3010, VIC, Australia. Hawkins.e@wehi.edu.au.

المصدر: Cell death and differentiation [Cell Death Differ] 2022 Dec; Vol. 29 (12), pp. 2519-2530. Date of Electronic Publication: 2022 Jul 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9437445 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5403 (Electronic) Linking ISSN: 13509047 NLM ISO Abbreviation: Cell Death Differ Subsets: MEDLINE

مواضيع طبية MeSH: Epigenesis, Genetic* , B-Lymphocytes*, Animals ; Humans ; Mice ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Cell Differentiation/genetics ; Gene Expression Profiling ; Phenotype ; Polycomb Repressive Complex 2/metabolism

المؤلفون: Simpson DS; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; The Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Pang J; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; The Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia; College of Life Sciences, Nankai University, Tianjin, 300071, China., Weir A; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; The Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Kong IY; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; The Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Fritsch M; Institute for Molecular Immunology, Centre for Molecular Medicine Cologne and Cologne Excellence Cluster on Cellular Stress Responses in Ageing-Associated Diseases, University of Cologne, Cologne, 50931, Germany., Rashidi M; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; The Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Cooney JP; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; The Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Davidson KC; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; The Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Speir M; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Department of Molecular and Translational Science, Monash University, Clayton, VIC, 3168, Australia., Djajawi TM; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Department of Molecular and Translational Science, Monash University, Clayton, VIC, 3168, Australia., Hughes S; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; The Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Mackiewicz L; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia., Dayton M; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia., Anderton H; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; The Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Doerflinger M; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; The Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Deng Y; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; The Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Huang AS; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; The Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Conos SA; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Department of Molecular and Translational Science, Monash University, Clayton, VIC, 3168, Australia., Tye H; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Department of Molecular and Translational Science, Monash University, Clayton, VIC, 3168, Australia., Chow SH; The Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC, 3800, Australia., Rahman A; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, 3052, Australia., Norton RS; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, 3052, Australia; ARC Centre for Fragment-Based Design, Monash University, Parkville, VIC, 3052, Australia., Naderer T; The Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC, 3800, Australia., Nicholson SE; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; The Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Burgio G; Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT, 2601, Australia., Man SM; Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT, 2601, Australia., Groom JR; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; The Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Herold MJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; The Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Hawkins ED; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; The Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Lawlor KE; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Department of Molecular and Translational Science, Monash University, Clayton, VIC, 3168, Australia., Strasser A; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; The Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Silke J; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; The Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Pellegrini M; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; The Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Kashkar H; Institute for Molecular Immunology, Centre for Molecular Medicine Cologne and Cologne Excellence Cluster on Cellular Stress Responses in Ageing-Associated Diseases, University of Cologne, Cologne, 50931, Germany., Feltham R; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; The Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia. Electronic address: feltham.r@wehi.edu.au., Vince JE; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia; The Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia. Electronic address: vince@wehi.edu.au.

المصدر: Immunity [Immunity] 2022 Mar 08; Vol. 55 (3), pp. 423-441.e9. Date of Electronic Publication: 2022 Feb 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19/*immunology , Caspase 8/*metabolism , Interferon-gamma/*metabolism , Lymphohistiocytosis, Hemophagocytic/*immunology , Macrophages/*immunology , Mitochondria/*metabolism , SARS-CoV-2/*physiology, Animals ; Caspase 8/genetics ; Cells, Cultured ; Cytotoxicity, Immunologic ; Humans ; Interferon-gamma/genetics ; Macrophage Activation ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Nitric Oxide Synthase Type II/metabolism ; Pathogen-Associated Molecular Pattern Molecules/immunology ; Signal Transduction ; bcl-2 Homologous Antagonist-Killer Protein/genetics ; bcl-2 Homologous Antagonist-Killer Protein/metabolism ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism

المؤلفون: Lelliott EJ; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Kong IY; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia., Zethoven M; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Ramsbottom KM; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Martelotto LG; Single Cell Innovation Laboratory, The University of Melbourne, Parkville, Victoria, Australia., Meyran D; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Université de Paris, INSERM, U976 HIPI Unit, Institut de Recherche Saint-Louis, Paris, France., Zhu JJ; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Costacurta M; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Kirby L; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Sandow JJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., Lim L; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Dominguez PM; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Todorovski I; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Haynes NM; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.; Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia., Beavis PA; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Neeson PJ; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Hawkins ED; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia., McArthur GA; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Parish IA; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Johnstone RW; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Oliaro J; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.; Department of Immunology, Central Clinical School, Monash University, Melbourne, Victoria, Australia., Sheppard KE; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. conor.kearney@petermac.org karen.sheppard@petermac.org stephin.vervoort@petermac.org.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.; Department of Biochemistry and Pharmacology, The University of Melbourne, Parkville, Victoria, Australia., Kearney CJ; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. conor.kearney@petermac.org karen.sheppard@petermac.org stephin.vervoort@petermac.org.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Vervoort SJ; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. conor.kearney@petermac.org karen.sheppard@petermac.org stephin.vervoort@petermac.org.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.

المصدر: Cancer discovery [Cancer Discov] 2021 Oct; Vol. 11 (10), pp. 2582-2601. Date of Electronic Publication: 2021 May 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*therapeutic use , Breast Neoplasms/*drug therapy , Piperazines/*therapeutic use , Protein Kinase Inhibitors/*therapeutic use , Pyridines/*therapeutic use, Animals ; Antineoplastic Agents/pharmacology ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Cyclin-Dependent Kinase 4/antagonists & inhibitors ; Cyclin-Dependent Kinase 6/antagonists & inhibitors ; Female ; Humans ; Memory T Cells/drug effects ; Mice ; Piperazines/pharmacology ; Protein Kinase Inhibitors/pharmacology ; Pyridines/pharmacology ; Xenograft Model Antitumor Assays

المؤلفون: Lopes M; Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal., Duarte TL; Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal., Teles MJ; Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal.; Department of Clinical Pathology, Centro Hospitalar Universitário São João, Porto, Portugal., Mosteo L; Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal., Chacim S; Department of Onco-Hematology, Instituto Português de Oncologia (IPO)-Porto, Portugal., Aguiar E; Department of Clinical Hematology, Centro Hospitalar Universitário São João, Porto, Portugal., Pereira-Reis J; Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal., Oliveira M; Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal., Silva AMN; REQUIMITE-LAQV, Department of Chemistry and Biochemistry, Faculdade de Ciências da Universidade do Porto (FCUP), Porto, Portugal., Gonçalves N; Department of Clinical Pathology, IPO, Porto, Portugal., Martins G; Department of Clinical Pathology, IPO, Porto, Portugal., Kong IY; The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia., Zethoven M; Bioinformatics Core Facility, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Vervoort S; Sir Peter MacCallum Department of Oncology, The University of Melbourne, VIC, Australia., Martins S; Department of Clinical Pathology, Centro Hospitalar Universitário São João, Porto, Portugal., Quintela M; Department of Onco-Hematology, Instituto Português de Oncologia (IPO)-Porto, Portugal., Hawkins ED; The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia., Trigo F; Department of Clinical Hematology, Centro Hospitalar Universitário São João, Porto, Portugal., Guimarães JT; Department of Clinical Pathology, Centro Hospitalar Universitário São João, Porto, Portugal.; Department of Biomedicine, Unit of Biochemistry, Faculdade de Medicina da Universidade do Porto, Porto, Portugal., Mariz JM; Department of Onco-Hematology, Instituto Português de Oncologia (IPO)-Porto, Portugal., Porto G; Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal.; Department of Molecular Pathology and Immunology, Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto, Portugal.; Department of Hematology, Centro Hospitalar Universitário do Porto, Porto, Portugal; and., Duarte D; Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal.; Department of Onco-Hematology, Instituto Português de Oncologia (IPO)-Porto, Portugal.; Department of Biomedicine, Unit of Biochemistry, Faculdade de Medicina da Universidade do Porto, Porto, Portugal.; Porto Comprehensive Cancer Center, Porto, Portugal.

المصدر: Blood advances [Blood Adv] 2021 Aug 24; Vol. 5 (16), pp. 3102-3112.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE

مواضيع طبية MeSH: Anemia* , Leukemia, Myeloid, Acute*, Animals ; Erythroblasts ; Humans ; Iron ; Mice ; Transferrin