المؤلفون: Yenan Bryceson, Konrad Krzewski

الإتاحة: http://journal.frontiersin.org/researchtopic/1496/molecular-mechanisms-regulating-cytotoxic-lymphocyte-development-and-function-and-their-associations
http://www.doabooks.org/doab?func=search&query=rid:17831

المؤلفون: Andrew R. Zinn, Luis Sifuentes-Dominguez, Aleksandra Gil-Krzewska, Katelynn M. Wilton, Petro Starokadomskyy, Ezra Burstein, Luis Rohena, Mary E. Peterson, Adam M. Lopez, Ann Ray, Brittany L. Overlee, Daniel D. Billadeau, Nick V. Grishin, Eyal Grunebaum, Konrad Krzewski, Qing Chen, Lisa N. Kinch

المصدر: JCI Insight

مصطلحات موضوعية: Cytotoxicity, Immunologic, 0301 basic medicine, DNA Repair, DNA polymerase, Cell, NK cells, Monogenic diseases, 03 medical and health sciences, 0302 clinical medicine, Minichromosome maintenance, Interferon, medicine, Humans, Gene, Inflammation, Innate immunity, Recombination, Genetic, Infectious disease, Okazaki fragments, biology, DNA replication, Skin Diseases, Genetic, Genetic Diseases, X-Linked, General Medicine, Molecular biology, Minichromosome Maintenance Complex Component 4, 3. Good health, Killer Cells, Natural, 030104 developmental biology, medicine.anatomical_structure, Lytic cycle, 030220 oncology & carcinogenesis, biology.protein, K562 Cells, Amyloidosis, Familial, Pigmentation Disorders, Research Article, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23463523d69f19909851f2fcd7bc89e9
https://doi.org/10.1172/jci.insight.125688

المؤلفون: Linjie Tian, Jacquice Davis, Ha-Na Lee, Yasmine Belkaid, Nicolas Bouladoux, Konrad Krzewski, Mariam Quinones, John E. Coligan

المصدر: Journal of Clinical Investigation. 127:1905-1917

مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Cell, Apoptosis, Inflammation, Biology, Proinflammatory cytokine, Interferon-gamma, Mice, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Secretion, Interferon gamma, Receptors, Immunologic, Mice, Knockout, Tumor Necrosis Factor-alpha, Dextran Sulfate, Dendritic Cells, General Medicine, Dendritic cell, Colitis, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Chronic Disease, Immunology, Tumor necrosis factor alpha, medicine.symptom, Research Article, 030215 immunology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24ef676a5fab96a48b59246e13ad0bc
https://doi.org/10.1172/jci89531

المؤلفون: Bernadette R. Gochuico, William A. Gahl, John E. Coligan, Konrad Krzewski, Yousuke Murakami, Melissa A. Merideth, Aleksandra Gil-Krzewska, Kevin J. O'Brien, Giovanna Peruzzi, Andrew R. Cullinane

المصدر: British Journal of Haematology. 176:118-123

مصطلحات موضوعية: Cytotoxicity, Immunologic, 0301 basic medicine, Natural Killer Cell Activity, medicine.medical_treatment, Cytoplasmic Granules, Exocytosis, Article, Pathogenesis, 03 medical and health sciences, 0302 clinical medicine, hemic and lymphatic diseases, Organelle, Humans, Medicine, Cytotoxicity, Cells, Cultured, Immunodeficiency, integumentary system, business.industry, Hematology, respiratory system, medicine.disease, eye diseases, Killer Cells, Natural, Phenotype, 030104 developmental biology, Cytokine, Hermanski-Pudlak Syndrome, 030220 oncology & carcinogenesis, Immunology, Hermansky–Pudlak syndrome, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29777f88c9baea80e136089b9907779
https://doi.org/10.1111/bjh.14390

المؤلفون: Konrad Krzewski, Yousuke Murakami, David H. Margulies, Jonathan M. Street, John E. Coligan, Chen-Feng Qi, Linjie Tian, Mirna Pena, Peter S.T. Yuen, Ha-Na Lee, Oliver H. Voss

المصدر: Immunity. 44:1365-1378

مصطلحات موضوعية: 0301 basic medicine, Toll-like receptor, Lipopolysaccharide, Immunology, Syk, Biology, Cell biology, 03 medical and health sciences, chemistry.chemical_compound, Interleukin 10, 030104 developmental biology, 0302 clinical medicine, Infectious Diseases, chemistry, 030220 oncology & carcinogenesis, Interleukin-21 receptor, TLR4, Immunology and Allergy, Myeloid Differentiation Factor 88, Signal transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::da8aca7bc20dd5af7ec7ce07ae1b1ed7
https://doi.org/10.1016/j.immuni.2016.05.005

المؤلفون: Huda Mussaffi, Eyal Grunebaum, Andrew R. Zinn, Adrijan Sarajlija, Jonathan J. Rios, Guadalupe Fraile, Naama Orenstein, Z. Xu, Chao Xing, Edward K. Wakeland, Petro Starokadomskyy, Nan Yan, Maria Teresa de la Morena, Ezra Burstein, Eulalia Baselga, Haiying Li, Konrad Krzewski, Lin Ma, Gianluca Tadini, Terry Gemelli, Igor Dozmorov, Dan Ben-Amitai, Zhimiao Lin, Prithvi Raj, Zhe Xu, Huijun Wang, Shaheen Khan, Vladislav Pokatayev, Richard C. Wang, Naoteru Miyata, Yong Yang

المصدر: Nature immunology
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

مصطلحات موضوعية: Male, 0301 basic medicine, DNA polymerase, DNA polymerase II, Immunoblotting, Immunology, DNA polymerase delta, Article, 03 medical and health sciences, chemistry.chemical_compound, Cytosol, Humans, Immunology and Allergy, Cells, Cultured, Oligonucleotide Array Sequence Analysis, Family Health, Microscopy, Confocal, Base Sequence, biology, Reverse Transcriptase Polymerase Chain Reaction, Gene Expression Profiling, DNA replication, RNA, Genetic Diseases, X-Linked, DNA, Fibroblasts, DNA Polymerase I, Molecular biology, Pedigree, 3. Good health, HEK293 Cells, 030104 developmental biology, chemistry, Interferon Type I, Mutation, Nucleic acid, biology.protein, Female, DNA polymerase I, Pigmentation Disorders, HeLa Cells

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bc678b9dedbef11a97fa013aa1e2910
https://doi.org/10.1038/ni.3409

المؤلفون: Oliver H. Voss, Chen-Feng Qi, Linjie Tian, Ha-Na Lee, Yousuke Murakami, Seung-Chul Choi, Sengottuvelu M, Konrad Krzewski, John E. Coligan

المصدر: Cell Death & Differentiation. 23:1086-1096

مصطلحات موضوعية: Antigens, Differentiation, T-Lymphocyte, CD4-Positive T-Lymphocytes, 0301 basic medicine, Priming (immunology), Apoptosis, CD8-Positive T-Lymphocytes, medicine.disease_cause, Autoimmune Diseases, Autoimmunity, Mice, 03 medical and health sciences, Antigen, Antigens, CD, medicine, Animals, Lectins, C-Type, Receptors, Immunologic, Efferocytosis, Molecular Biology, Autoantibodies, Mice, Knockout, Autoimmune disease, Original Paper, Thymocytes, Terpenes, Antigen processing, business.industry, Macrophages, Receptors, IgG, Dendritic Cells, Cell Biology, medicine.disease, Mice, Inbred C57BL, Hyaluronan Receptors, 030104 developmental biology, medicine.anatomical_structure, Immunology, business, Memory T cell, Spleen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29a2a620af4fc5c0c2af02ebef08125
https://doi.org/10.1038/cdd.2015.161

المؤلفون: Linjie Tian, Oliver H. Voss, John E. Coligan, Ha-Na Lee, Konrad Krzewski

المصدر: Current Protocols in Immunology

مصطلحات موضوعية: 0301 basic medicine, Phagocytosis, Immunology, Cell, Apoptosis, Receptors, Cell Surface, 02 engineering and technology, Article, 03 medical and health sciences, chemistry.chemical_compound, medicine, Animals, Efferocytosis, Lipid bilayer, Phospholipids, Liposome, Thymocytes, Vesicle, Phosphatidylserine, Surface Plasmon Resonance, 021001 nanoscience & nanotechnology, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, chemistry, Liposomes, lipids (amino acids, peptides, and proteins), 0210 nano-technology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2604985dd7e2d8bac669fae77c41558
https://pubmed.ncbi.nlm.nih.gov/29512142

المؤلفون: Konrad Krzewski, Magnus Nordenskjöld, Wendy J. Introne, Umran Caliskan, Hans-Gustaf Ljunggren, Fatma Burcu Belen, Jan-Inge Henter, H. Haluk Akar, Sandra Ammann, Yenan T. Bryceson, Hüseyin Tokgöz, Marie Meeths, Ayşegül Ünüvar, Zühre Kaya, Stephan Ehl, Kai Lehmberg, Bianca Tesi, Waleed Al-Herz, Turkan Patiroglu, Stephanie M. Wood, Samuel C. C. Chiang

المصدر: Frontiers in Immunology

مصطلحات موضوعية: 0301 basic medicine, Cell type, Endosome, Endocytic cycle, Immunology, NK cells, Biology, Exocytosis, 03 medical and health sciences, Interleukin 21, lysosomes, Lysosome, hemic and lymphatic diseases, medicine, Cytotoxic T cell, Immunology and Allergy, lytic granule polarization, Original Research, Chédiak–Higashi syndrome, cytotoxic T cells, medicine.disease, Chediak–Higashi syndrome, Cell biology, 030104 developmental biology, medicine.anatomical_structure, endosomes, exocytosis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17014cb284fbca82403e72adae493401
https://avesis.gazi.edu.tr/publication/details/7f9a034e-1b40-44f4-a07a-d70f216ad898/oai

المؤلفون: Aleksandra, Gil-Krzewska, Mezida B, Saeed, Anna, Oszmiana, Elizabeth R, Fischer, Kathryn, Lagrue, William A, Gahl, Wendy J, Introne, John E, Coligan, Daniel M, Davis, Konrad, Krzewski

المصدر: The Journal of Allergy and Clinical Immunology

مصطلحات موضوعية: actin cytoskeleton, LAMP, Lysosome-associated membrane protein, ICAM-1, Intercellular adhesion molecule 1, Vesicular Transport Proteins, cytotoxic lymphocyte, CHS, Chediak-Higashi syndrome, lysosomal trafficking regulator, Cytoplasmic Granules, CI-MPR, Cation-independent mannose 6-phosphate receptor, Article, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, Cell Line, lysosomes, NK, Natural killer, EV, Empty vector, Humans, EEA1, Early Endosome Antigen 1, Cytoskeleton, ARM, Armadillo repeats, HEAT, Huntingtin, elongation factor 3 (EF3), protein phosphatase 2A (PP2A), and the lipid kinase TOR repeats, CTL, Cytotoxic T cell, natural killer cell, immune deficiency, Actins, HLH, Hemophagocytic lymphohistiocytosis, Killer Cells, Natural, MTOC, Microtubule organizing center, Chediak-Higashi syndrome, CMFDA, 5-chloromethylfluorescein diacetate, cytotoxicity, lytic granules, PSF, Point spread function, exocytosis, Rab, Ras-associated binding protein, LYST, Lysosomal trafficking regulator

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::a91967078f0db25dd5ebb544ade025fd
https://pubmed.ncbi.nlm.nih.gov/29241728