المؤلفون: Irina Petrushina, Armine Hovakimyan, Indira S. Harahap-Carrillo, Hayk Davtyan, Tatevik Antonyan, Gor Chailyan, Konstantin Kazarian, Maxim Antonenko, Amandine Jullienne, Mary M. Hamer, Andre Obenaus, Olga King, Karen Zagorski, Mathew Blurton-Jones, David H. Cribbs, Harry Lander, Anahit Ghochikyan, Michael G. Agadjanyan

المصدر: Neurobiology of Disease, Vol 139, Iss , Pp 104823- (2020)

مصطلحات موضوعية: Alzheimer's disease (AD), DNA Aβ-vaccine, Biodistribution, Safety toxicology, Magnetic resonance imaging (MRI), Immunohistochemistry (IHC), Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S096999612030098X; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/89f760f61a67409099ed9195e4e4ddd0

المؤلفون: Michael G. Agadjanyan, Karen Zagorski, Irina Petrushina, Hayk Davtyan, Konstantin Kazarian, Maxim Antonenko, Joy Davis, Charles Bon, Mathew Blurton-Jones, David H. Cribbs, Anahit Ghochikyan

المصدر: Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-18 (2017)

مصطلحات موضوعية: Alzheimer’s disease, Tauopathy, Phosphatase activation domain, Immunotherapy, Monoclonal antibody, Humanization, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13024-017-0172-1; https://doaj.org/toc/1750-1326

URL الوصول: https://doaj.org/article/778c20749b314dc7952c275a87e5b6a6

المؤلفون: Patrick J. Brennan, Konstantin Kazarian, Pavel Ivanov, Alexander S. Apt, Sergey E. Lyubimov, Boris Nikonenko, Konstantin B. Majorov, Valeriya S. Velezheva, Albert G. Kornienko

المصدر: Bioorganic & Medicinal Chemistry Letters. 26:978-985

مصطلحات موضوعية: Thiosemicarbazones, Indoles, Pyridines, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Hydrazine, Antitubercular Agents, Pharmaceutical Science, Microbial Sensitivity Tests, Antimycobacterial, Hydrazide, 01 natural sciences, Biochemistry, Mycobacterium tuberculosis, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Drug Resistance, Bacterial, Drug Discovery, Pyridine, medicine, Structure–activity relationship, Molecular Biology, Indole test, biology, 010405 organic chemistry, Organic Chemistry, Hydrazones, biology.organism_classification, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Hydrazines, chemistry, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3212df69013c7a1ef8566410af1bcb60
https://doi.org/10.1016/j.bmcl.2015.12.049

المؤلفون: Michael G. Agadjanyan, Mathew Blurton-Jones, Harry Lander, David H. Cribbs, Konstantin Kazarian, Anahit Ghochikyan, Karen Zagorski, Irina Petrushina, Mary Hamer, Olga King, Gor Chailyan, Andre Obenaus, Hayk Davtyan, Armine Hovakimyan, Indira S. Harahap-Carrillo, Maxim Antonenko, Amandine Jullienne, Tatevik Antonyan

المصدر: Neurobiology of disease
Neurobiology of Disease, Vol 139, Iss, Pp 104823-(2020)

مصطلحات موضوعية: 0301 basic medicine, Aging, Pathology, Neurodegenerative, Alzheimer's Disease, Transgenic, Epitope, Mice, 0302 clinical medicine, Biodistribution, Immunologic, Vaccines, DNA, DNA A beta-vaccine, Safety toxicology, Vaccines, Clinical Trials as Topic, Immunohistochemistry, Vaccination, medicine.anatomical_structure, Neurology, 5.1 Pharmaceuticals, Neurological, Alzheimer's disease (AD), DNA Aβ-vaccine, Cerebral amyloid angiopathy, Development of treatments and therapeutic interventions, medicine.medical_specialty, Alzheimer Vaccines, Clinical Sciences, Mice, Transgenic, Neuropathology, Article, lcsh:RC321-571, DNA vaccination, Vaccine Related, 03 medical and health sciences, Magnetic resonance imaging, Adjuvants, Immunologic, Alzheimer Disease, Acquired Cognitive Impairment, medicine, Animals, Humans, Adjuvants, Magnetic resonance imaging (MRI), lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, B cell, Neurology & Neurosurgery, Amyloid beta-Peptides, Animal, business.industry, Prevention, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), DNA, medicine.disease, Peptide Fragments, Brain Disorders, Immunohistochemistry (IHC), Cerebral Amyloid Angiopathy, Disease Models, Animal, 030104 developmental biology, Mouse models of AD, Disease Models, Antibody Formation, Immunization, Dementia, business, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a38369a8b23d5be8107fe1e6753701
http://europepmc.org/articles/PMC8772258

المؤلفون: Janet Petrosyan, Natalie R.S. Goldberg, Mathew Blurton-Jones, Eliezer Masliah, Anahit Ghochikyan, David H. Cribbs, Konstantin Kazarian, Irina Petrushina, Karen Zagorski, Hayk Davtyan, Michael G. Agadjanyan

المصدر: Neurobiology of aging. 59

مصطلحات موضوعية: 0301 basic medicine, Aging, and promotion of well-being, Helper-Inducer, T-Lymphocytes, Cell, MultiTEP platform, T-cell mapping, Neurodegenerative, Inbred C57BL, Epitope, Transgenic, chemistry.chemical_compound, Mice, Epitopes, 0302 clinical medicine, Vaccines, DNA, 2.1 Biological and endogenous factors, Aetiology, Vaccines, Parkinson's Disease, biology, General Neuroscience, Immunogenicity, B-Lymphocyte, Neurodegenerative Diseases, T-Lymphocytes, Helper-Inducer, Anti-alpha-synuclein antibodies, medicine.anatomical_structure, 3.4 Vaccines, Neurological, alpha-Synuclein, Epitopes, B-Lymphocyte, Female, Antibody, Biotechnology, Genetically modified mouse, Clinical Sciences, Mice, Transgenic, Antibodies, Article, DNA vaccination, DNA vaccines, Vaccine Related, 03 medical and health sciences, Rare Diseases, medicine, Acquired Cognitive Impairment, Animals, Humans, Alpha-synuclein, Synucleinopathies, Neurology & Neurosurgery, B-cell mapping, Prevention, Neurosciences, DNA, Anti-α-synuclein antibodies, Prevention of disease and conditions, Brain Disorders, Mice, Inbred C57BL, 030104 developmental biology, chemistry, nervous system, Immunology, biology.protein, Immunization, Dementia, Neurology (clinical), Geriatrics and Gerontology, Therapeutic potency, 030217 neurology & neurosurgery, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7113cfba9659e58b3c3bb8fc66bca4
https://pubmed.ncbi.nlm.nih.gov/28870518

المؤلفون: Michael G. Agadjanyan, Maxim Antonenko, Hayk Davtyan, Konstantin Kazarian, Irina Petrushina, Karen Zagorski, Mathew Blurton-Jones, Anahit Ghochikyan, David H. Cribbs, Joy Davis, Charles Bon

المصدر: Molecular Neurodegeneration
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-18 (2017)
Agadjanyan, Michael G; Zagorski, Karen; Petrushina, Irina; Davtyan, Hayk; Kazarian, Konstantin; Antonenko, Maxim; et al.(2017). Humanized monoclonal antibody armanezumab specific to N-terminus of pathological tau: characterization and therapeutic potency.. Molecular neurodegeneration, 12(1), 33. doi: 10.1186/s13024-017-0172-1. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9ft272mr

مصطلحات موضوعية: 0301 basic medicine, Clone (cell biology), lcsh:Geriatrics, Epitope, lcsh:RC346-429, Mice, 0302 clinical medicine, Antibody Specificity, Chemistry, Brain, Alzheimer's disease, Humanization, 3. Good health, Tauopathy, Tauopathies, Immunotherapy, Alzheimer’s disease, Research Article, Genetically modified mouse, Monoclonal antibody, medicine.drug_class, Clinical Sciences, Mice, Transgenic, tau Proteins, Antibodies, Monoclonal, Humanized, 03 medical and health sciences, Cellular and Molecular Neuroscience, In vivo, mental disorders, Genetics, medicine, Animals, Humans, Molecular Biology, lcsh:Neurology. Diseases of the nervous system, Neurology & Neurosurgery, Neurosciences, Phosphatase activation domain, medicine.disease, Virology, Molecular biology, Therapeutic efficacy, lcsh:RC952-954.6, 030104 developmental biology, Epitope mapping, Neurology (clinical), 030217 neurology & neurosurgery, Ex vivo

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::721fab3452086f04f92a0d470b12bc5e
https://pubmed.ncbi.nlm.nih.gov/28472993

المؤلفون: Hayk Davtyan, David H. Cribbs, Joy Davis, Michael G. Agadjanyan, Mathew Blurton-Jones, Anahit Ghochikyan, Karen Zagorski, Wesley W. Chen, Konstantin Kazarian, Irina Petrushina

المصدر: Vaccine, vol 35, iss 16

مصطلحات موضوعية: 0301 basic medicine, Aging, and promotion of well-being, Enzyme-Linked Immunospot Assay, Neurodegenerative, Adaptive Immunity, Alzheimer's Disease, Medical and Health Sciences, Transgenic, Epitope, Mice, Epitopes, Alzheimer's diseases, 0302 clinical medicine, Vaccines, DNA, Transgenic mice, Lymphocytes, Vaccines, Intramuscular, biology, Blotting, ELISPOT, Tau immunotherapy, Anti-tau antibody, Brain, Biological Sciences, Acquired immune system, Immunohistochemistry, DNA epitope vaccine, Vaccination, Infectious Diseases, Treatment Outcome, 3.4 Vaccines, 5.1 Pharmaceuticals, Molecular Medicine, Female, Development of treatments and therapeutic interventions, Antibody, Western, Biotechnology, Blotting, Western, Enzyme-Linked Immunosorbent Assay, Mice, Transgenic, tau Proteins, Injections, Intramuscular, Antibodies, Article, Injections, DNA vaccination, Vaccine Related, 03 medical and health sciences, Alzheimer’s diseases, Immune system, Alzheimer Disease, Virology, Acquired Cognitive Impairment, Animals, Humans, Agricultural and Veterinary Sciences, General Veterinary, General Immunology and Microbiology, Animal, Prevention, Neurosciences, Public Health, Environmental and Occupational Health, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), DNA, Prevention of disease and conditions, Brain Disorders, Disease Models, Animal, Good Health and Well Being, 030104 developmental biology, Disease Models, Immunology, Humoral immunity, biology.protein, Dementia, Immunization, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715feabc74d3222215602b485015ecf0
https://pubmed.ncbi.nlm.nih.gov/28320590

المؤلفون: Nikolai Petrovsky, Irina Petrushina, Konstantin Kazarian, Arpine Davtyan, Hayk Davtyan, Harinda Rajapaksha, Michael G. Agadjanyan, Armine Hovakimyan, David H. Cribbs, Karen Zagorski, Anahit Ghochikyan

المصدر: Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Alzheimer Vaccines, medicine.medical_treatment, tau Proteins, Article, Epitope, 03 medical and health sciences, 0302 clinical medicine, Immune system, Adjuvants, Immunologic, Alzheimer Disease, medicine, Animals, Humans, Amyloid beta-Peptides, Multidisciplinary, biology, business.industry, Immunogenicity, Inulin, Antibody titer, Brain, Vaccine efficacy, 3. Good health, Mice, Inbred C57BL, 030104 developmental biology, Immunization, Antibody Formation, Immunology, biology.protein, Epitopes, B-Lymphocyte, Female, Antibody, business, Adjuvant, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62270cfec255b27f3fba49482e57632b

المؤلفون: Maxim Antonenko, Irina Petrushina, David H. Cribbs, Anahit Ghochikyan, Karen Zagorski, Joy Davis, Mathew Blurton-Jones, Wesley W. Chen, Konstantin Kazarian, Hayk Davtyan, Michael G. Agadjanyan

المصدر: Alzheimer's & Dementia. 12

مصطلحات موضوعية: Epidemiology, Chemistry, medicine.drug_class, Health Policy, Monoclonal antibody, Molecular biology, N-terminus, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, medicine, Potency, Neurology (clinical), Geriatrics and Gerontology, Pathological

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::70fe49c6f32884ad321ad9fddc223516
https://doi.org/10.1016/j.jalz.2016.06.467

المؤلفون: Menico Rizzi, Konstantin Kazarian, Camilla Cassani

المصدر: Protein Expression and Purification. 69:215-218

مصطلحات موضوعية: Adenosine Triphosphatases, Tuberculosis, biology, Latent tuberculosis, Mycobacterium smegmatis, DNA Helicases, Helicase, DNA, Mycobacterium tuberculosis, medicine.disease_cause, biology.organism_classification, medicine.disease, Virology, Microbiology, Expression procedure, Bacterial Proteins, Latent Tuberculosis, medicine, biology.protein, Humans, Cloning, Molecular, Escherichia coli, Biotechnology, Genome stability

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8588704a8cc5c4d8810feee6777b361
https://doi.org/10.1016/j.pep.2009.09.006