المؤلفون: Koo CZ; School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.; Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Midlands B15 2TT, UK., Matthews AL; School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.; Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Midlands B15 2TT, UK., Harrison N; School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK., Szyroka J; School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK., Nieswandt B; Institute of Experimental Biomedicine I, University Hospital and Rudolf Virchow Center Würzburg, University of Würzburg, D-97080 Würzburg, Germany., Gardiner EE; Division of Genome Science and Cancer, John Curtin School of Medical Research, Australian National University, Canberra ACT 2601, Australia., Poulter NS; Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Midlands B15 2TT, UK.; Institute of Cardiovascular Sciences, University of Birmingham, Birmingham B15 2TT, UK., Tomlinson MG; School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.; Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Midlands B15 2TT, UK.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2022 Feb 23; Vol. 23 (5). Date of Electronic Publication: 2022 Feb 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: ADAM10 Protein/*metabolism , Amyloid Precursor Protein Secretases/*metabolism , Membrane Proteins/*metabolism , Platelet Membrane Glycoproteins/*genetics , Tetraspanins/*genetics , Tetraspanins/*metabolism, Blood Platelets/metabolism ; CRISPR-Cas Systems ; Gene Knockout Techniques ; HEK293 Cells ; Humans ; Platelet Membrane Glycoproteins/metabolism ; Protein Domains ; Proteolysis ; Substrate Specificity ; Tetraspanins/chemistry

المؤلفون: Harrison N; School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK., Koo CZ; School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.; Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Midlands, UK., Tomlinson MG; School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.; Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Midlands, UK.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2021 Jun 23; Vol. 22 (13). Date of Electronic Publication: 2021 Jun 23.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: ADAM10 Protein/*physiology , Tetraspanins/*physiology, Amyloid Precursor Protein Secretases/physiology ; Animals ; Cadherins/metabolism ; Humans ; Membrane Proteins/metabolism ; Membrane Proteins/physiology ; Molecular Targeted Therapy/methods ; Tetraspanins/chemistry

المؤلفون: Seifert A; Institute of Molecular Pharmacology, Medical Faculty, RWTH Aachen University, Aachen, Germany., Düsterhöft S; Institute of Molecular Pharmacology, Medical Faculty, RWTH Aachen University, Aachen, Germany., Wozniak J; Institute of Molecular Pharmacology, Medical Faculty, RWTH Aachen University, Aachen, Germany., Koo CZ; School of Biosciences, University of Birmingham, Birmingham, UK., Tomlinson MG; School of Biosciences, University of Birmingham, Birmingham, UK., Nuti E; Department of Pharmacy, University of Pisa, Pisa, Italy., Rossello A; Department of Pharmacy, University of Pisa, Pisa, Italy., Cuffaro D; Department of Pharmacy, University of Pisa, Pisa, Italy., Yildiz D; Institute of Molecular Pharmacology, Medical Faculty, RWTH Aachen University, Aachen, Germany.; Institute of Experimental and Clinical Pharmacology and Toxicology, PZMS, ZHMB, Saarland University, Homburg, Germany., Ludwig A; Institute of Molecular Pharmacology, Medical Faculty, RWTH Aachen University, Aachen, Germany. aludwig@ukaachen.de.; Institute of Pharmacology and Toxicology, RWTH Aachen University, Pauwelsstr. 30, 52074, Aachen, Germany. aludwig@ukaachen.de.

المصدر: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2021 Jan; Vol. 78 (2), pp. 715-732. Date of Electronic Publication: 2020 May 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE

مواضيع طبية MeSH: ADAM10 Protein/*metabolism , Amyloid Precursor Protein Secretases/*metabolism , Extracellular Vesicles/*metabolism , Membrane Proteins/*metabolism, ADAM10 Protein/analysis ; ADAM10 Protein/genetics ; Amyloid Precursor Protein Secretases/analysis ; Amyloid Precursor Protein Secretases/genetics ; Animals ; Cell Line ; Cell Membrane/genetics ; Cell Membrane/metabolism ; Extracellular Vesicles/genetics ; Humans ; Loss of Function Mutation ; Male ; Membrane Proteins/analysis ; Membrane Proteins/genetics ; Mice, Inbred C57BL ; Proteolysis ; Mice

المؤلفون: Koo CZ; School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom.; Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Midlands B15 2TT, United Kingdom., Harrison N; School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom., Noy PJ; School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom., Szyroka J; School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom., Matthews AL; School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom., Hsia HE; German Center for Neurodegenerative Diseases (DZNE) Munich, Neuroproteomics, Klinikum rechts der Isar, Technical University Munich and Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany., Müller SA; German Center for Neurodegenerative Diseases (DZNE) Munich, Neuroproteomics, Klinikum rechts der Isar, Technical University Munich and Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany., Tüshaus J; German Center for Neurodegenerative Diseases (DZNE) Munich, Neuroproteomics, Klinikum rechts der Isar, Technical University Munich and Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany., Goulding J; Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Midlands B15 2TT, United Kingdom.; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham NG7 2UH, United Kingdom., Willis K; School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom., Apicella C; School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom., Cragoe B; School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom., Davis E; School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom., Keles M; School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom., Malinova A; School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom., McFarlane TA; School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom., Morrison PR; School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom., Nguyen HTH; School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom., Sykes MC; School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom., Ahmed H; School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom., Di Maio A; School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom., Seipold L; Institute of Biochemistry, Christian Albrechts University Kiel, 24118 Kiel, Germany., Saftig P; Institute of Biochemistry, Christian Albrechts University Kiel, 24118 Kiel, Germany., Cull E; School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom., Pliotas C; School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, United Kingdom., Rubinstein E; Sorbonne Université, INSERM, CNRS, Centre d'Immunologie et des Maladies Infectieuses, CIMI-Paris, Paris 75013, France., Poulter NS; Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Midlands B15 2TT, United Kingdom.; Institute of Cardiovascular Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom., Briddon SJ; Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Midlands B15 2TT, United Kingdom.; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham NG7 2UH, United Kingdom., Holliday ND; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham NG7 2UH, United Kingdom., Lichtenthaler SF; German Center for Neurodegenerative Diseases (DZNE) Munich, Neuroproteomics, Klinikum rechts der Isar, Technical University Munich and Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany., Tomlinson MG; School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom m.g.tomlinson@bham.ac.uk.; Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Midlands B15 2TT, United Kingdom.

المصدر: The Journal of biological chemistry [J Biol Chem] 2020 Sep 04; Vol. 295 (36), pp. 12822-12839. Date of Electronic Publication: 2020 Feb 28.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: ADAM10 Protein/*metabolism , Amyloid Precursor Protein Secretases/*metabolism , Membrane Proteins/*metabolism , Multiprotein Complexes/*metabolism , Tetraspanins/*metabolism, A549 Cells ; ADAM10 Protein/genetics ; Amyloid Precursor Protein Secretases/genetics ; Animals ; HEK293 Cells ; Humans ; Jurkat Cells ; Membrane Proteins/genetics ; Mice ; Mice, Knockout ; Multiprotein Complexes/genetics ; Tetraspanins/genetics

المؤلفون: Gavin RL; School of Biosciences, University of Birmingham, Birmingham, UK., Koo CZ; School of Biosciences, University of Birmingham, Birmingham, UK., Tomlinson MG; School of Biosciences, University of Birmingham, Birmingham, UK. m.g.tomlinson@bham.ac.uk.

المصدر: Medical microbiology and immunology [Med Microbiol Immunol] 2020 Aug; Vol. 209 (4), pp. 553-564. Date of Electronic Publication: 2020 May 23.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0314524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1831 (Electronic) Linking ISSN: 03008584 NLM ISO Abbreviation: Med Microbiol Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Inflammation/*physiopathology , Tetraspanins/*physiology , Thrombosis/*physiopathology, Animals ; Blood Platelets/metabolism ; Calcium Signaling ; Chick Embryo ; Embryonic Development ; Endothelial Cells ; Gene Knockdown Techniques ; Humans ; Mice ; Mice, Knockout ; ORAI1 Protein/immunology ; ORAI1 Protein/metabolism ; Platelet Membrane Glycoproteins/metabolism

المؤلفون: Noy PJ; School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK., Gavin RL; School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK., Colombo D; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Haining EJ; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Reyat JS; School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK., Payne H; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Thielmann I; University Hospital Würzburg and Rudolf Virchow Center for Experimental Biomedicine, Würzburg, Germany., Lokman AB; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Neag G; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Yang J; School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK., Lloyd T; School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK., Harrison N; School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK., Heath VL; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Gardiner C; Department of Haematology, University College London, London, UK., Whitworth KM; Institute of Immunology and Immunotherapy, Cancer Immunology and Immunotherapy Centre, University of Birmingham, Birmingham, UK., Robinson J; Institute of Immunology and Immunotherapy, Cancer Immunology and Immunotherapy Centre, University of Birmingham, Birmingham, UK., Koo CZ; School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK., Di Maio A; School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK., Harrison P; Scar Free Foundation for Burns Research, Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham National Health Service (NHS) Foundation Trust, Birmingham, UK.; Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK., Lee SP; Institute of Immunology and Immunotherapy, Cancer Immunology and Immunotherapy Centre, University of Birmingham, Birmingham, UK., Michelangeli F; Department of Biological Sciences, University of Chester, Chester, UK., Kalia N; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.; Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Birmingham-Nottingham, UK., Rainger GE; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Nieswandt B; University Hospital Würzburg and Rudolf Virchow Center for Experimental Biomedicine, Würzburg, Germany., Brill A; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.; Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Birmingham-Nottingham, UK.; Department of Pathophysiology, Sechenov First Moscow State Medical University, Moscow, Russia., Watson SP; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.; Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Birmingham-Nottingham, UK., Tomlinson MG; School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK m.g.tomlinson@bham.ac.uk.; Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Birmingham-Nottingham, UK.

المصدر: Haematologica [Haematologica] 2019 Sep; Vol. 104 (9), pp. 1892-1905. Date of Electronic Publication: 2018 Dec 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Ferrata Storti Foundation Country of Publication: Italy NLM ID: 0417435 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1592-8721 (Electronic) Linking ISSN: 03906078 NLM ISO Abbreviation: Haematologica Subsets: MEDLINE

مواضيع طبية MeSH: Calcium/*metabolism , Myocardial Reperfusion Injury/*genetics , ORAI1 Protein/*genetics , Tetraspanins/*genetics , Venous Thrombosis/*genetics , von Willebrand Factor/*genetics, Animals ; B-Lymphocytes/cytology ; B-Lymphocytes/drug effects ; B-Lymphocytes/metabolism ; Chickens ; Disease Models, Animal ; Gene Expression Regulation ; HEK293 Cells ; HeLa Cells ; Histamine/pharmacology ; Human Umbilical Vein Endothelial Cells/cytology ; Human Umbilical Vein Endothelial Cells/drug effects ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Ion Transport/drug effects ; Jurkat Cells ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Myocardial Reperfusion Injury/metabolism ; Myocardial Reperfusion Injury/pathology ; NFATC Transcription Factors/genetics ; NFATC Transcription Factors/metabolism ; ORAI1 Protein/metabolism ; Signal Transduction ; Tetraspanins/metabolism ; Thrombin/pharmacology ; Venous Thrombosis/metabolism ; Venous Thrombosis/pathology ; von Willebrand Factor/metabolism

المؤلفون: Matthews AL; School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, United Kingdom., Koo CZ; School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, United Kingdom.; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham, Birmingham, United Kingdom., Szyroka J; School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, United Kingdom., Harrison N; School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, United Kingdom., Kanhere A; School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, United Kingdom., Tomlinson MG; School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, United Kingdom.; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham, Birmingham, United Kingdom.

المصدر: Frontiers in immunology [Front Immunol] 2018 Jul 02; Vol. 9, pp. 1451. Date of Electronic Publication: 2018 Jul 02 (Print Publication: 2018).

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Print ISSN: 1664-3224 (Print) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: PubMed not MEDLINE