المؤلفون: Menden, MP, Wang, D, Mason, MJ, Szalai, B, Bulusu, KC, Guan, YF, Yu, T, Kang, J, Jeon, M, Wolfinger, R, Nguyen, T, Zaslavskiy, M, Jang, IS, Ghazoui, Z, Ahsen, ME, Vogel, R, Neto, EC, Norman, T, Tang, EKY, Garnett, MJ, Di Veroli, GY, Fawell, S, Stolovitzky, G, Guinney, J, Dry, JR, Saez-Rodriguez, J, Abante, J, Abecassis, BS, Aben, N, Aghamirzaie, D, Aittokallio, T, Akhtari, FS, Al-lazikani, B, Alam, T, Allam, A, Allen, C, de Almeida, MP, Altarawy, D, Alves, V, Amadoz, A, Anchang, B, Antolin, AA, Ash, JR, Aznar, VR, Ba-alawi, W, Bagheri, M, Bajic, V, Ball, G, Ballester, PJ, Baptista, D, Bare, C, Bateson, M, Bender, A, Bertrand, D, Wijayawardena, B, Boroevich, KA, Bosdriesz, E, Bougouffa, S, Bounova, G, Brouwer, T, Bryant, B, Calaza, M, Calderone, A, Calza, S, Capuzzi, S, Carbonell-Caballero, J, Carlin, D, Carter, H, Castagnoli, L, Celebi, R, Cesareni, G, Chang, H, Chen, GC, Chen, HR, Chen, HY, Cheng, LJ, Chernomoretz, A, Chicco, D, Cho, KH, Cho, S, Choi, D, Choi, J, Choi, K, Choi, M, De Cock, M, Coker, E, Cortes-Ciriano, I, Cserzo, M, Cubuk, C, Curtis, C, Van Daele, D, Dang, CC, Dijkstra, T, Dopazo, J, Draghici, S, Drosou, A, Dumontier, M, Ehrhart, F, Eid, FE, ElHefnawi, M, Elmarakeby, H, van Engelen, B, Engin, HB, de Esch, I, Evelo, C, Falcao, AO, Farag, S, Fernandez-Lozano, C, Fisch, K, Flobak, A, Fornari, C, Foroushani, ABK, Fotso, DC, Fourches, D, Friend, S, Frigessi, A, Gao, F, Gao, XT, Gerold, JM, Gestraud, P, Ghosh, S, Gillberg, J, Godoy-Lorite, A, Godynyuk, L, Godzik, A, Goldenberg, A, Gomez-Cabrero, D, Gonen, M, de Graaf, C, Gray, H, Grechkin, M, Guimera, R, Guney, E, Haibe-Kains, B, Han, Y, Hase, T, He, D, He, LY, Heath, LS, Hellton, KH, Helmer-Citterich, M, Hidalgo, MR, Hidru, D, Hill, SM, Hochreiter, S, Hong, S, Hovig, E, Hsueh, YC, Hu, ZY, Huang, JK, Huang, RS, Hunyady, L, Hwang, J, Hwang, TH, Hwang, W, Hwang, Y, Isayev, O, Walk, OBD, Jack, J, Jahandideh, S, Ji, JD, Jo, Y, Kamola, PJ, Kanev, GK, Karacosta, L, Karimi, M, Kaski, S, Kazanov, M, Khamis, AM, Khan, SA, Kiani, NA, Kim, A, Kim, J, Kim, K, Kim, S, Kim, Y, Kirk, PDW, Kitano, H, Klambauer, G, Knowles, D, Ko, M, Kohn-Luque, A, Kooistra, AJ, Kuenemann, MA, Kuiper, M, Kurz, C, Kwon, M, van Laarhoven, T, Laegreid, A, Lederer, S, Lee, H, Lee, J, Lee, YW, Leppaho, E, Lewis, R, Li, J, Li, L, Liley, J, Lim, WK, Lin, C, Liu, YY, Lopez, Y, Low, J, Lysenko, A, Machado, D, Madhukar, N, De Maeyer, D, Malpartida, AB, Mamitsuka, H, Marabita, F, Marchal, K, Marttinen, P, Mason, D, Mazaheri, A, Mehmood, A, Mehreen, A, Michaut, M, Miller, RA, Mitsopoulos, C, Modos, D, Van Moerbeke, M, Moo, K, Motsinger-Reif, A, Movva, R, Muraru, S, Muratov, E, Mushthofa, M, Nagarajan, N, Nakken, S, Nath, A, Neuvial, P, Newton, R, Ning, Z, De Niz, C, Oliva, B, Olsen, C, Palmeri, A, Panesar, B, Papadopoulos, S, Park, J, Park, S, Pawitan, Y, Peluso, D, Pendyala, S, Peng, J, Perfetto, L, Pirro, S, Plevritis, S, Politi, R, Poon, H, Porta, E, Prellner, I, Preuer, K, Pujana, MA, Ramnarine, R, Reid, JE, Reyal, F, Richardson, S, Ricketts, C, Rieswijk, L, Rocha, M, Rodriguez-Gonzalvez, C, Roell, K, Rotroff, D, de Ruiter, JR, Rukawa, P, Sadacca, B, Safikhani, Z, Safitri, F, Sales-Pardo, M, Sauer, S, Schlichting, M, Seoane, JA, Serra, J, Shang, MM, Sharma, A, Sharma, H, Shen, Y, Shiga, M, Shin, M, Shkedy, Z, Shopsowitz, K, Sinai, S, Skola, D, Smirnov, P, Soerensen, IF, Soerensen, P, Song, JH, Song, SO, Soufan, O, Spitzmueller, A, Steipe, B, Suphavilai, C, Tamayo, SP, Tamborero, D, Tang, J, Tanoli, ZUR, Tarres-Deulofeu, M, Tegner, J, Thommesen, L, Tonekaboni, SAM, Tran, H, De Troyer, E, Truong, A, Tsunoda, T, Turu, G, Tzeng, GY, Verbeke, L, Videla, S, Vis, D, Voronkov, A, Votis, K, Wang, A, Wang, HQH, Wang, PW, Wang, S, Wang, W, Wang, XC, Wang, X, Wennerberg, K, Wernisch, L, Wessels, L, van Westen, GJP, Westerman, BA, White, SR, Willighagen, E, Wurdinger, T, Xie, L, Xie, SL, Xu, H, Yadav, B, Yau, C, Yeerna, H, Yin, JW, Yu, M, Yun, SJ, Zakharov, A, Zamichos, A, Zanin, M, Zeng, L, Zenil, H, Zhang, F, Zhang, PY, Zhang, W, Zhao, HY, Zhao, L, Zheng, WJ, Zoufir, A, Zucknick, M

المصدر: Nature communications. 10(1):2674

مصطلحات موضوعية: Medicin och hälsovetenskap, Medicinska och farmaceutiska grundvetenskaper, Farmaceutiska vetenskaper, Naturvetenskap, Data- och informationsvetenskap (Datateknik), Bioinformatik (beräkningsbiologi) (tillämpningar under 10610), Klinisk medicin, Cancer och onkologi

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:141113030

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

المؤلفون: McNaught-Flores DA; Amsterdam Institute for Molecules, Medicines, and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, VU University Amsterdam, Amsterdam, The Netherlands (D.A.M.-F., A.J.K., R.L.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.J.K.); Department of Anatomy, University of Helsinki, Helsinki, Finland (Y.-C.C., P.P.); and Departamento de Fisiología, Biofísica y Neurociencias, Centro de Investigación y de Estudios Avanzados del IPN, Ciudad de México, México (J.-A.A.-M.)., Kooistra AJ; Amsterdam Institute for Molecules, Medicines, and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, VU University Amsterdam, Amsterdam, The Netherlands (D.A.M.-F., A.J.K., R.L.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.J.K.); Department of Anatomy, University of Helsinki, Helsinki, Finland (Y.-C.C., P.P.); and Departamento de Fisiología, Biofísica y Neurociencias, Centro de Investigación y de Estudios Avanzados del IPN, Ciudad de México, México (J.-A.A.-M.)., Chen YC; Amsterdam Institute for Molecules, Medicines, and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, VU University Amsterdam, Amsterdam, The Netherlands (D.A.M.-F., A.J.K., R.L.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.J.K.); Department of Anatomy, University of Helsinki, Helsinki, Finland (Y.-C.C., P.P.); and Departamento de Fisiología, Biofísica y Neurociencias, Centro de Investigación y de Estudios Avanzados del IPN, Ciudad de México, México (J.-A.A.-M.)., Arias-Montano JA; Amsterdam Institute for Molecules, Medicines, and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, VU University Amsterdam, Amsterdam, The Netherlands (D.A.M.-F., A.J.K., R.L.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.J.K.); Department of Anatomy, University of Helsinki, Helsinki, Finland (Y.-C.C., P.P.); and Departamento de Fisiología, Biofísica y Neurociencias, Centro de Investigación y de Estudios Avanzados del IPN, Ciudad de México, México (J.-A.A.-M.)., Panula P; Amsterdam Institute for Molecules, Medicines, and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, VU University Amsterdam, Amsterdam, The Netherlands (D.A.M.-F., A.J.K., R.L.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.J.K.); Department of Anatomy, University of Helsinki, Helsinki, Finland (Y.-C.C., P.P.); and Departamento de Fisiología, Biofísica y Neurociencias, Centro de Investigación y de Estudios Avanzados del IPN, Ciudad de México, México (J.-A.A.-M.)., Leurs R; Amsterdam Institute for Molecules, Medicines, and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, VU University Amsterdam, Amsterdam, The Netherlands (D.A.M.-F., A.J.K., R.L.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.J.K.); Department of Anatomy, University of Helsinki, Helsinki, Finland (Y.-C.C., P.P.); and Departamento de Fisiología, Biofísica y Neurociencias, Centro de Investigación y de Estudios Avanzados del IPN, Ciudad de México, México (J.-A.A.-M.) r.leurs@vu.nl.

المصدر: Molecular pharmacology [Mol Pharmacol] 2024 Jan 10; Vol. 105 (2), pp. 84-96. Date of Electronic Publication: 2024 Jan 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0035623 Publication Model: Electronic Cited Medium: Internet ISSN: 1521-0111 (Electronic) Linking ISSN: 0026895X NLM ISO Abbreviation: Mol Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Histamine* , Receptors, Histamine H1*/genetics , Receptors, Histamine H1*/metabolism, Animals ; Humans ; Pyrilamine/pharmacology ; Pyrilamine/metabolism ; Zebrafish ; Signal Transduction

المؤلفون: Kanev GK; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Department of Neurosurgery, Amsterdam University Medical Centers, Cancer Center Amsterdam, Brain Tumor Center Amsterdam, Amsterdam, The Netherlands., Zhang Y; Department of Neurosurgery, Amsterdam University Medical Centers, Cancer Center Amsterdam, Brain Tumor Center Amsterdam, Amsterdam, The Netherlands., Kooistra AJ; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Bender A; Centre for Molecular Science Informatics, Department of Chemistry, University of Cambridge, Cambridge, United Kingdom., Leurs R; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Bailey D; The WINDOW consortium, www.window-consortium.org.; IOTA Pharmaceuticals Ltd, St Johns Innovation Centre, Cambridge, United Kingdom., Würdinger T; Department of Neurosurgery, Amsterdam University Medical Centers, Cancer Center Amsterdam, Brain Tumor Center Amsterdam, Amsterdam, The Netherlands.; The WINDOW consortium, www.window-consortium.org., de Graaf C; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., de Esch IJP; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Westerman BA; Department of Neurosurgery, Amsterdam University Medical Centers, Cancer Center Amsterdam, Brain Tumor Center Amsterdam, Amsterdam, The Netherlands.; The WINDOW consortium, www.window-consortium.org.

المصدر: PLoS computational biology [PLoS Comput Biol] 2023 Sep 05; Vol. 19 (9), pp. e1011301. Date of Electronic Publication: 2023 Sep 05 (Print Publication: 2023).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE

مواضيع طبية MeSH: Drug Delivery Systems* , Machine Learning*, Neural Networks, Computer ; Protein Kinase Inhibitors/pharmacology ; Workflow

المؤلفون: Caroli J; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Mamyrbekov A; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.; Trial Data Management, Novo Nordisk A/S, Søborg, Denmark., Harpsøe K; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Gardizi S; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.; IFP Manufacturing Development, Novo Nordisk A/S, Bagsværd, Denmark., Dörries L; Department of Biochemistry, Justus Liebig University Giessen, Giessen, Germany., Ghosh E; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Hauser AS; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Kooistra AJ; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark. albert.kooistra@sund.ku.dk., Gloriam DE; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark. david.gloriam@sund.ku.dk.

المصدر: Nature chemical biology [Nat Chem Biol] 2023 May; Vol. 19 (5), pp. 531-535.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction*

المؤلفون: Pándy-Szekeres G; Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.; Medicinal Chemistry Research Group, Research Center for Natural Sciences, Budapest H-1117, Hungary., Caroli J; Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark., Mamyrbekov A; Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark., Kermani AA; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Keserű GM; Medicinal Chemistry Research Group, Research Center for Natural Sciences, Budapest H-1117, Hungary., Kooistra AJ; Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark., Gloriam DE; Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.

المصدر: Nucleic acids research [Nucleic Acids Res] 2023 Jan 06; Vol. 51 (D1), pp. D395-D402.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, G-Protein-Coupled*/chemistry , Databases, Protein*, Humans ; Ligands ; Mutation ; Sequence Alignment ; Signal Transduction ; Protein Conformation

المؤلفون: Sydow D; In Silico Toxicology and Structural Bioinformatics, Institute of Physiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany., Aßmann E; In Silico Toxicology and Structural Bioinformatics, Institute of Physiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany., Kooistra AJ; Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark., Rippmann F; Computational Chemistry & Biologics, Merck Healthcare KGaA, Frankfurter Str. 250, 64293 Darmstadt, Germany., Volkamer A; In Silico Toxicology and Structural Bioinformatics, Institute of Physiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.

المصدر: Journal of chemical information and modeling [J Chem Inf Model] 2022 May 23; Vol. 62 (10), pp. 2600-2616. Date of Electronic Publication: 2022 May 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE

مواضيع طبية MeSH: Protein Kinase Inhibitors*/chemistry , Protein Kinase Inhibitors*/pharmacology , Protein Kinases*/metabolism, Binding Sites ; Humans ; Ligands ; Polypharmacology

المؤلفون: Pándy-Szekeres G; Department of Drug Design and Pharmacology, University of Copenhagen, 2100 Copenhagen, Denmark.; Medicinal Chemistry Research Group, Research Centre for Natural Sciences, Budapest H-1117, Hungary., Esguerra M; Department of Drug Design and Pharmacology, University of Copenhagen, 2100 Copenhagen, Denmark., Hauser AS; Department of Drug Design and Pharmacology, University of Copenhagen, 2100 Copenhagen, Denmark., Caroli J; Department of Drug Design and Pharmacology, University of Copenhagen, 2100 Copenhagen, Denmark., Munk C; Department of Drug Design and Pharmacology, University of Copenhagen, 2100 Copenhagen, Denmark., Pilger S; Department of Drug Design and Pharmacology, University of Copenhagen, 2100 Copenhagen, Denmark., Keserű GM; Medicinal Chemistry Research Group, Research Centre for Natural Sciences, Budapest H-1117, Hungary., Kooistra AJ; Department of Drug Design and Pharmacology, University of Copenhagen, 2100 Copenhagen, Denmark., Gloriam DE; Department of Drug Design and Pharmacology, University of Copenhagen, 2100 Copenhagen, Denmark.

المصدر: Nucleic acids research [Nucleic Acids Res] 2022 Jan 07; Vol. 50 (D1), pp. D518-D525.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: Databases, Protein* , Software*, GTP-Binding Proteins/*metabolism , Prescription Drugs/*chemistry , Receptors, G-Protein-Coupled/*metabolism , Small Molecule Libraries/*chemistry, Amino Acid Sequence ; Binding Sites ; Eukaryotic Cells/cytology ; Eukaryotic Cells/drug effects ; Eukaryotic Cells/metabolism ; GTP-Binding Proteins/antagonists & inhibitors ; GTP-Binding Proteins/chemistry ; GTP-Binding Proteins/genetics ; Gene Expression Regulation ; Humans ; Models, Molecular ; Molecular Sequence Annotation ; Mutation ; Prescription Drugs/pharmacology ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; Receptors, G-Protein-Coupled/antagonists & inhibitors ; Receptors, G-Protein-Coupled/chemistry ; Receptors, G-Protein-Coupled/genetics ; Sequence Alignment ; Sequence Homology, Amino Acid ; Signal Transduction ; Small Molecule Libraries/pharmacology ; Structure-Activity Relationship

المؤلفون: Kooistra AJ; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark. albert.kooistra@sund.ku.dk., Munk C; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.; Data Tools Department, Novozymes A/S, Copenhagen, Denmark., Hauser AS; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Gloriam DE; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark. david.gloriam@sund.ku.dk.

المصدر: Nature structural & molecular biology [Nat Struct Mol Biol] 2021 Nov; Vol. 28 (11), pp. 875-878. Date of Electronic Publication: 2021 Nov 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Databases, Protein*, Protein Structure, Secondary/*physiology , Receptors, G-Protein-Coupled/*metabolism, Amino Acid Sequence ; Internet

المؤلفون: Hauser AS; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Kooistra AJ; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Munk C; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.; Data Tools Department, Novozymes A/S, Copenhagen, Denmark., Heydenreich FM; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, Quebec, Canada.; Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, UK., Veprintsev DB; Centre of Membrane Proteins and Receptors (COMPARE), University of Nottingham, Nottingham, UK.; Division of Physiology, Pharmacology & Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, UK., Bouvier M; Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, Quebec, Canada., Babu MM; Department of Structural Biology and Center for Data Driven Discovery, St. Jude Children's Research Hospital, Memphis, TN, USA., Gloriam DE; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark. david.gloriam@sund.ku.dk.

المصدر: Nature structural & molecular biology [Nat Struct Mol Biol] 2021 Nov; Vol. 28 (11), pp. 879-888. Date of Electronic Publication: 2021 Nov 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Protein Conformation*, Enzyme Activation/*physiology , Receptors, G-Protein-Coupled/*classification , Receptors, G-Protein-Coupled/*metabolism, Computational Biology ; Databases, Protein ; Humans ; Signal Transduction/physiology