المؤلفون: Vázquez Torres S; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Graduate Program in Biological Physics, Structure and Design, University of Washington, Seattle, WA, USA., Leung PJY; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Graduate Program in Molecular Engineering, University of Washington, Seattle, WA, USA., Venkatesh P; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Graduate Program in Biological Physics, Structure and Design, University of Washington, Seattle, WA, USA., Lutz ID; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Department of Bioengineering, University of Washington, Seattle, WA, USA., Hink F; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Huynh HH; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA., Becker J; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA., Yeh AH; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Juergens D; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Graduate Program in Molecular Engineering, University of Washington, Seattle, WA, USA., Bennett NR; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Graduate Program in Molecular Engineering, University of Washington, Seattle, WA, USA., Hoofnagle AN; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA., Huang E; Department of Genome Sciences, University of Washington, Seattle, WA, USA., MacCoss MJ; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Expòsit M; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Graduate Program in Molecular Engineering, University of Washington, Seattle, WA, USA., Lee GR; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Bera AK; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Kang A; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., De La Cruz J; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Levine PM; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Li X; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Lamb M; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Gerben SR; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Murray A; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Heine P; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Korkmaz EN; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Nivala J; School of Computer Science and Engineering, University of Washington, Seattle, WA, USA.; Molecular Engineering and Sciences Institute, University of Washington, Seattle, WA, USA., Stewart L; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Watson JL; Department of Biochemistry, University of Washington, Seattle, WA, USA. jwatson3@uw.edu.; Institute for Protein Design, University of Washington, Seattle, WA, USA. jwatson3@uw.edu., Rogers JM; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark. joseph.rogers@sund.ku.dk., Baker D; Department of Biochemistry, University of Washington, Seattle, WA, USA. dabaker@uw.edu.; Institute for Protein Design, University of Washington, Seattle, WA, USA. dabaker@uw.edu.; Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA. dabaker@uw.edu.

المصدر: Nature [Nature] 2024 Feb; Vol. 626 (7998), pp. 435-442. Date of Electronic Publication: 2023 Dec 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Computer-Aided Design* , Deep Learning* , Peptides*/chemistry , Peptides*/metabolism , Proteins*/chemistry , Proteins*/metabolism, Biosensing Techniques ; Diffusion ; Glucagon/chemistry ; Glucagon/metabolism ; Luminescent Measurements ; Mass Spectrometry ; Parathyroid Hormone/chemistry ; Parathyroid Hormone/metabolism ; Protein Structure, Secondary ; Substrate Specificity ; Models, Molecular

المؤلفون: Bhimsaria D; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706.; Department of Electrical and Computer Engineering, University of Wisconsin-Madison, Madison, WI 53706., Rodríguez-Martínez JA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706., Pan J; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706., Roston D; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706., Korkmaz EN; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706., Cui Q; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706., Ramanathan P; Department of Electrical and Computer Engineering, University of Wisconsin-Madison, Madison, WI 53706., Ansari AZ; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706; azansari@wisc.edu.; The Genome Center of Wisconsin, University of Wisconsin-Madison, Madison, WI 53706.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2018 Nov 06; Vol. 115 (45), pp. E10586-E10595. Date of Electronic Publication: 2018 Oct 19.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: DNA/*metabolism , Transcription Factors/*metabolism, Binding Sites ; SELEX Aptamer Technique ; Thermodynamics

المؤلفون: Pham GH; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, 53706., Rana AS; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, 53706., Korkmaz EN; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, 53706., Trang VH; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, 53706., Cui Q; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, 53706., Strieter ER; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, 53706.

المصدر: Protein science : a publication of the Protein Society [Protein Sci] 2016 Feb; Vol. 25 (2), pp. 456-71. Date of Electronic Publication: 2016 Jan 12.

نوع المنشور: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9211750 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-896X (Electronic) Linking ISSN: 09618368 NLM ISO Abbreviation: Protein Sci Subsets: MEDLINE

مواضيع طبية MeSH: Ubiquitin/*chemistry, Animals ; Databases, Protein ; Humans ; Hydrolysis ; Models, Molecular ; Protein Conformation ; Protein Multimerization ; Scattering, Small Angle ; Ubiquitin/metabolism ; Ubiquitin-Specific Proteases/metabolism ; X-Ray Diffraction

المؤلفون: Korkmaz EN; Department of Chemistry and Theoretical Chemistry Institute, University of Wisconsin, Madison, WI 53706, USA., Taylor KC; Department of Biochemistry, University of Wisconsin, 433 Babcock Drive, Madison, WI 53706, USA., Andreas MP; Department of Biochemistry, University of Wisconsin, 433 Babcock Drive, Madison, WI 53706, USA., Ajay G; Department of Biochemistry, University of Wisconsin, 433 Babcock Drive, Madison, WI 53706, USA., Heinze NT; Department of Biochemistry, University of Wisconsin, 433 Babcock Drive, Madison, WI 53706, USA., Cui Q; Department of Chemistry and Theoretical Chemistry Institute, University of Wisconsin, Madison, WI 53706, USA., Rayment I; Department of Biochemistry, University of Wisconsin, 433 Babcock Drive, Madison, WI 53706, USA.

المصدر: Proteins [Proteins] 2016 Jan; Vol. 84 (1), pp. 172-189. Date of Electronic Publication: 2015 Dec 09.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8700181 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0134 (Electronic) Linking ISSN: 08873585 NLM ISO Abbreviation: Proteins Subsets: MEDLINE

مواضيع طبية MeSH: Myosin Subfragments/*chemistry, Amino Acid Sequence ; Cardiomyopathies/genetics ; Crystallography, X-Ray ; Humans ; Molecular Dynamics Simulation ; Molecular Sequence Data ; Mutation ; Myosin Subfragments/genetics ; Protein Conformation ; Protein Stability ; Protein Structure, Secondary ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/genetics ; Temperature

المؤلفون: Korkmaz EN; †Graduate Program in Biophysics, University of Wisconsin-Madison, 1525 Linden Drive, Madison, Wisconsin 53706, United States., Volkman BF; ‡Department of Biochemistry, Medical College of Wisconsin, 8701 Watertown Plank Rd., Milwaukee, Wisconsin 53226, United States., Cui Q; †Graduate Program in Biophysics, University of Wisconsin-Madison, 1525 Linden Drive, Madison, Wisconsin 53706, United States.; §Department of Chemistry and Theoretical Chemistry Institute, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53706, United States.

المصدر: The journal of physical chemistry. B [J Phys Chem B] 2015 Jul 30; Vol. 119 (30), pp. 9547-58. Date of Electronic Publication: 2015 Jul 16.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101157530 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5207 (Electronic) Linking ISSN: 15205207 NLM ISO Abbreviation: J Phys Chem B Subsets: MEDLINE

مواضيع طبية MeSH: Hydrophobic and Hydrophilic Interactions* , Static Electricity*, Lymphokines/*chemistry , Sialoglycoproteins/*chemistry, Humans ; Molecular Dynamics Simulation ; Protein Stability ; Protein Structure, Secondary ; Thermodynamics

المؤلفون: Taylor KC; Department of Biochemistry, University of Wisconsin, Madison, WI 53706;, Buvoli M; Department of Molecular, Cellular, and Developmental Biology and Bio Frontiers Institute, University of Colorado, Boulder, CO 80309;, Korkmaz EN; Department of Chemistry and Theoretical Chemistry Institute, University of Wisconsin, Madison, WI 53706., Buvoli A; Department of Molecular, Cellular, and Developmental Biology and Bio Frontiers Institute, University of Colorado, Boulder, CO 80309;, Zheng Y; Department of Chemistry and Theoretical Chemistry Institute, University of Wisconsin, Madison, WI 53706., Heinze NT; Department of Biochemistry, University of Wisconsin, Madison, WI 53706;, Cui Q; Department of Chemistry and Theoretical Chemistry Institute, University of Wisconsin, Madison, WI 53706 cui@chem.wisc.edu Leslie.Leinwand@colorado.edu ivan_rayment@biochem.wisc.edu., Leinwand LA; Department of Molecular, Cellular, and Developmental Biology and Bio Frontiers Institute, University of Colorado, Boulder, CO 80309; cui@chem.wisc.edu Leslie.Leinwand@colorado.edu ivan_rayment@biochem.wisc.edu., Rayment I; Department of Biochemistry, University of Wisconsin, Madison, WI 53706; cui@chem.wisc.edu Leslie.Leinwand@colorado.edu ivan_rayment@biochem.wisc.edu.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2015 Jul 21; Vol. 112 (29), pp. E3806-15. Date of Electronic Publication: 2015 Jul 06.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Amino Acids/*chemistry , Cardiac Myosins/*chemistry , Cardiac Myosins/*metabolism , Myosin Heavy Chains/*chemistry , Myosin Heavy Chains/*metabolism , Myosin Subfragments/*chemistry , Myosin Subfragments/*metabolism, Amino Acid Sequence ; Humans ; Molecular Dynamics Simulation ; Molecular Sequence Data ; Mutant Proteins/chemistry ; Mutant Proteins/metabolism ; Pliability ; Protein Stability ; Protein Structure, Secondary ; Repetitive Sequences, Amino Acid ; Sarcomeres/metabolism ; Sequence Deletion ; Structure-Activity Relationship

المؤلفون: Xing Y; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin 53706, USA. xing@oncology.wisc.edu, Nukaya M, Satyshur KA, Jiang L, Stanevich V, Korkmaz EN, Burdette L, Kennedy GD, Cui Q, Bradfield CA

المصدر: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2012 Sep; Vol. 129 (1), pp. 86-97. Date of Electronic Publication: 2012 Jun 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Aryl Hydrocarbon/*metabolism, Amino Acid Sequence ; Benzo(a)pyrene/metabolism ; Ligands ; Models, Molecular ; Molecular Dynamics Simulation ; Molecular Sequence Data ; Mutation ; Polychlorinated Dibenzodioxins/metabolism ; Protein Conformation ; Receptors, Aryl Hydrocarbon/chemistry ; Receptors, Aryl Hydrocarbon/genetics

المؤلفون: Korkmaz EN; Polymer Research Center & Chemical Engineering Department, Boğaziçi University, Istanbul, Turkey., Nussinov R, Haliloğlu T

المصدر: PLoS computational biology [PLoS Comput Biol] 2012; Vol. 8 (3), pp. e1002420. Date of Electronic Publication: 2012 Mar 15.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE

مواضيع طبية MeSH: Models, Chemical* , Models, Molecular* , Transcriptional Activation*, CREB-Binding Protein/*chemistry , Myeloid-Lymphoid Leukemia Protein/*chemistry , Proto-Oncogene Proteins c-myb/*chemistry, Binding Sites ; CREB-Binding Protein/ultrastructure ; Computer Simulation ; Histone-Lysine N-Methyltransferase ; Myeloid-Lymphoid Leukemia Protein/ultrastructure ; Protein Binding ; Protein Conformation ; Protein Structure, Tertiary ; Proto-Oncogene Mas ; Proto-Oncogene Proteins c-myb/ultrastructure