المؤلفون: Buravchenko GI; Gause Institute of New Antibiotics, 11 B. Pirogovskaya Street, Moscow 119021, Russia; Mendeleyev University of Chemical Technology, 9 Miusskaya Square, Moscow 125190, Russia. Electronic address: buravchenkogi@gmail.com., Scherbakov AM; Blokhin National Medical Research Center of Oncology, 24 Kashirskoye sh., Moscow 115522, Russia. Electronic address: alex.scherbakov@gmail.com., Dezhenkova LG; Gause Institute of New Antibiotics, 11 B. Pirogovskaya Street, Moscow 119021, Russia. Electronic address: dezhenkovalg@yahoo.com., Bykov EE; Gause Institute of New Antibiotics, 11 B. Pirogovskaya Street, Moscow 119021, Russia., Solovieva SE; Gause Institute of New Antibiotics, 11 B. Pirogovskaya Street, Moscow 119021, Russia., Korlukov AA; Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilova St., Moscow 119991, Russia., Sorokin DV; Blokhin National Medical Research Center of Oncology, 24 Kashirskoye sh., Moscow 115522, Russia. Electronic address: dsorokin2018@gmail.com., Monzote Fidalgo L; Department of Parasitology, Pedro Kouri Tropical Medicine Institute, Havana, Cuba. Electronic address: monzote@ipk.sld.cu., Shchekotikhin AE; Gause Institute of New Antibiotics, 11 B. Pirogovskaya Street, Moscow 119021, Russia. Electronic address: shchekotikhin@mail.ru.

المصدر: Bioorganic chemistry [Bioorg Chem] 2020 Nov; Vol. 104, pp. 104324. Date of Electronic Publication: 2020 Sep 28.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

مواضيع طبية MeSH: Drug Discovery*, Antineoplastic Agents/*pharmacology , Cell Hypoxia/*drug effects , Hypoxia-Inducible Factor 1, alpha Subunit/*antagonists & inhibitors , Nitriles/*pharmacology , Quinoxalines/*pharmacology , Receptors, Estrogen/*antagonists & inhibitors, Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Apoptosis/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Molecular Structure ; Nitriles/chemical synthesis ; Nitriles/chemistry ; Quinoxalines/chemical synthesis ; Quinoxalines/chemistry ; Receptors, Estrogen/metabolism ; Structure-Activity Relationship