المؤلفون: Zhu Y; Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford University, Stanford, CA., Shudo Y, He H, Kim JY, Elde S, Williams KM, Walsh SK, Koyano TK, Guenthart B, Woo YJ

المصدر: Transplantation [Transplantation] 2023 May 01; Vol. 107 (5), pp. 1151-1157. Date of Electronic Publication: 2023 Apr 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0132144 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1534-6080 (Electronic) Linking ISSN: 00411337 NLM ISO Abbreviation: Transplantation Subsets: MEDLINE

مواضيع طبية MeSH: Heart Transplantation*/methods , Heart Transplantation*/statistics & numerical data , Tissue and Organ Procurement*/methods , Tissue and Organ Procurement*/standards, Humans ; Ischemia/prevention & control ; Proportional Hazards Models ; Retrospective Studies ; Temperature ; Treatment Outcome ; Male ; Female ; Adult ; Middle Aged ; Survival Analysis

المؤلفون: Shudo Y; Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA 94305-5407, USA., Benjamin-Addy R; Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA 94305-5407, USA., Koyano TK; Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA 94305-5407, USA., Hiesinger W; Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA 94305-5407, USA., MacArthur JW; Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA 94305-5407, USA., Woo YJ; Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA 94305-5407, USA.

المصدر: Future cardiology [Future Cardiol] 2021 Jan; Vol. 17 (1), pp. 11-17. Date of Electronic Publication: 2020 Jul 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Future Medicine Country of Publication: England NLM ID: 101239345 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-8298 (Electronic) Linking ISSN: 14796678 NLM ISO Abbreviation: Future Cardiol Subsets: MEDLINE

مواضيع طبية MeSH: Heart Failure*/therapy , Heart Transplantation* , Tissue and Organ Procurement*, Heart ; Humans ; Tissue Donors

المؤلفون: Iosef C; Department of Cardiothoracic Surgery, Stanford University, 300 Pasteur Dr, Falk CVRB, Stanford, CA, 94305, USA., Pedroza AJ; Department of Cardiothoracic Surgery, Stanford University, 300 Pasteur Dr, Falk CVRB, Stanford, CA, 94305, USA., Cui JZ; Department of Cardiothoracic Surgery, Stanford University, 300 Pasteur Dr, Falk CVRB, Stanford, CA, 94305, USA., Dalal AR; Department of Cardiothoracic Surgery, Stanford University, 300 Pasteur Dr, Falk CVRB, Stanford, CA, 94305, USA., Arakawa M; Department of Cardiothoracic Surgery, Stanford University, 300 Pasteur Dr, Falk CVRB, Stanford, CA, 94305, USA., Tashima Y; Department of Cardiothoracic Surgery, Stanford University, 300 Pasteur Dr, Falk CVRB, Stanford, CA, 94305, USA., Koyano TK; Department of Cardiothoracic Surgery, Stanford University, 300 Pasteur Dr, Falk CVRB, Stanford, CA, 94305, USA., Burdon G; Department of Cardiothoracic Surgery, Stanford University, 300 Pasteur Dr, Falk CVRB, Stanford, CA, 94305, USA., Churovich SMP; Department of Cardiothoracic Surgery, Stanford University, 300 Pasteur Dr, Falk CVRB, Stanford, CA, 94305, USA., Orrick JO; Department of Cardiothoracic Surgery, Stanford University, 300 Pasteur Dr, Falk CVRB, Stanford, CA, 94305, USA., Pariani M; Department of Pediatrics-Genetics, Stanford University, Stanford, CA, USA., Fischbein MP; Department of Cardiothoracic Surgery, Stanford University, 300 Pasteur Dr, Falk CVRB, Stanford, CA, 94305, USA. mfischbe@stanford.edu.

المصدر: Scientific reports [Sci Rep] 2020 Nov 23; Vol. 10 (1), pp. 20392. Date of Electronic Publication: 2020 Nov 23.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Aorta/*metabolism , Aortic Aneurysm, Thoracic/*genetics , Induced Pluripotent Stem Cells/*metabolism , Marfan Syndrome/*genetics , Neural Crest/*metabolism , Proteomics/*methods, Aorta/pathology ; Aortic Aneurysm, Thoracic/metabolism ; Aortic Aneurysm, Thoracic/pathology ; Case-Control Studies ; Cell Adhesion ; Cell Differentiation ; Cell Lineage/genetics ; Female ; Fibrillin-1/genetics ; Fibrillin-1/metabolism ; Fibronectins/genetics ; Fibronectins/metabolism ; Gene Expression Profiling ; Gene Expression Regulation ; Humans ; Induced Pluripotent Stem Cells/pathology ; Integrins/genetics ; Integrins/metabolism ; Laminin/genetics ; Laminin/metabolism ; Leukocytes, Mononuclear/metabolism ; Leukocytes, Mononuclear/pathology ; Mannose-Binding Lectins/genetics ; Mannose-Binding Lectins/metabolism ; Marfan Syndrome/metabolism ; Marfan Syndrome/pathology ; Membrane Glycoproteins/genetics ; Membrane Glycoproteins/metabolism ; Mesoderm/metabolism ; Mesoderm/pathology ; Neural Crest/pathology ; Primary Cell Culture ; Receptors, Cell Surface/genetics ; Receptors, Cell Surface/metabolism ; Young Adult

المؤلفون: Greene CL; Department of Cardiothoracic Surgery, Stanford University, Stanford, CA 94305, USA., Jaatinen KJ; Department of Cardiothoracic Surgery, Stanford University, Stanford, CA 94305, USA., Wang H; Department of Cardiothoracic Surgery, Stanford University, Stanford, CA 94305, USA.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA 94305, USA., Koyano TK; Department of Cardiothoracic Surgery, Stanford University, Stanford, CA 94305, USA., Bilbao MS; Department of Cardiothoracic Surgery, Stanford University, Stanford, CA 94305, USA., Woo YJ; Department of Cardiothoracic Surgery, Stanford University, Stanford, CA 94305, USA.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA 94305, USA.; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.

المصدر: Genes [Genes (Basel)] 2020 Jul 14; Vol. 11 (7). Date of Electronic Publication: 2020 Jul 14.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4425 (Electronic) Linking ISSN: 20734425 NLM ISO Abbreviation: Genes (Basel) Subsets: MEDLINE

مواضيع طبية MeSH: Transcription, Genetic*, Aortic Valve/*metabolism , Aortic Valve Stenosis/*genetics , Gene Regulatory Networks/*genetics, Adult ; Aged ; Aortic Valve/pathology ; Aortic Valve Disease/genetics ; Aortic Valve Disease/pathology ; Aortic Valve Stenosis/pathology ; Calcinosis/genetics ; Calcinosis/pathology ; Constriction, Pathologic/genetics ; Constriction, Pathologic/pathology ; Female ; Gene Expression Regulation/genetics ; Heart Transplantation/adverse effects ; High-Throughput Nucleotide Sequencing ; Humans ; Male ; Middle Aged ; RNA-Seq

المؤلفون: Emrich F; Department of Cardiothoracic Surgery, Stanford University, Stanford, California.; Department of Cardiothoracic Surgery, Leipzig University Heart Center, Leipzig, Germany., Penov K; Department of Cardiothoracic Surgery, Stanford University, Stanford, California.; Department of Cardiothoracic Surgery, Leipzig University Heart Center, Leipzig, Germany., Arakawa M; Department of Cardiothoracic Surgery, Stanford University, Stanford, California.; Department of Cardiovascular Surgery, Jichi Medical University, Saitama, Japan., Dhablania N; Department of Cardiothoracic Surgery, Stanford University, Stanford, California., Burdon G; Department of Cardiothoracic Surgery, Stanford University, Stanford, California., Pedroza AJ; Department of Cardiothoracic Surgery, Stanford University, Stanford, California., Koyano TK; Department of Cardiothoracic Surgery, Stanford University, Stanford, California., Kim YM; Department of Cardiovascular Medicine, Stanford University, Stanford, California., Raaz U; Department of Cardiovascular Medicine, Stanford University, Stanford, California., Connolly AJ; Department of Pathology, Stanford University, Stanford, California., Iosef C; Department of Cardiothoracic Surgery, Stanford University, Stanford, California., Fischbein MP; Department of Cardiothoracic Surgery, Stanford University, Stanford, California.

المصدر: Journal of cellular and molecular medicine [J Cell Mol Med] 2019 Oct; Vol. 23 (10), pp. 7000-7009. Date of Electronic Publication: 2019 Aug 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1582-4934 (Electronic) Linking ISSN: 15821838 NLM ISO Abbreviation: J Cell Mol Med Subsets: MEDLINE

مواضيع طبية MeSH: Aneurysm/*complications , Aneurysm/*metabolism , Marfan Syndrome/*complications , Marfan Syndrome/*metabolism , Reactive Oxygen Species/*metabolism, Acetophenones/pharmacology ; Angiotensin II ; Animals ; Aorta/metabolism ; Aorta/pathology ; Disease Models, Animal ; Fibrillin-1/deficiency ; Fibrillin-1/metabolism ; Mice, Inbred C57BL ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/metabolism ; NADPH Oxidases/metabolism

المؤلفون: Wirka RC; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford, CA, USA., Wagh D; Stanford Functional Genomics Facility, Stanford University School of Medicine, Stanford, CA, USA., Paik DT; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford, CA, USA., Pjanic M; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford, CA, USA., Nguyen T; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford, CA, USA., Miller CL; Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia, Charlottesville, VA, USA., Kundu R; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford, CA, USA., Nagao M; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford, CA, USA., Coller J; Stanford Functional Genomics Facility, Stanford University School of Medicine, Stanford, CA, USA., Koyano TK; Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA., Fong R; Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA., Woo YJ; Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA., Liu B; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Montgomery SB; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Wu JC; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford, CA, USA., Zhu K; Department of Neurology, University of Arizona, Tucson, AZ, USA.; Center for Innovation in Brain Science, University of Arizona, Tucson, AZ, USA., Chang R; Department of Neurology, University of Arizona, Tucson, AZ, USA.; Center for Innovation in Brain Science, University of Arizona, Tucson, AZ, USA., Alamprese M; Department of Neurology, University of Arizona, Tucson, AZ, USA.; Center for Innovation in Brain Science, University of Arizona, Tucson, AZ, USA., Tallquist MD; Center for Cardiovascular Research, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA., Kim JB; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford, CA, USA., Quertermous T; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA. tomq1@stanford.edu.; Stanford Cardiovascular Institute, Stanford, CA, USA. tomq1@stanford.edu.

المصدر: Nature medicine [Nat Med] 2019 Aug; Vol. 25 (8), pp. 1280-1289. Date of Electronic Publication: 2019 Jul 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE

مواضيع طبية MeSH: Basic Helix-Loop-Helix Transcription Factors/*genetics , Coronary Artery Disease/*prevention & control , Myocytes, Smooth Muscle/*physiology , Single-Cell Analysis/*methods, Animals ; Basic Helix-Loop-Helix Transcription Factors/physiology ; Cells, Cultured ; Humans ; Mice ; Mice, Inbred C57BL ; Osteoprotegerin/genetics ; Phenotype ; Polymorphism, Single Nucleotide ; Sequence Analysis, RNA

المؤلفون: Paulsen MJ; Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif., Kasinpila P; Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif., Imbrie-Moore AM; Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif; Department of Mechanical Engineering, Stanford University, Stanford, Calif., Wang H; Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif., Hironaka CE; Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif., Koyano TK; Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif., Fong R; Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif., Chiu P; Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif., Goldstone AB; Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif., Steele AN; Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif; Department of Bioengineering, Stanford University, Stanford, Calif., Stapleton LM; Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif; Department of Bioengineering, Stanford University, Stanford, Calif., Ma M; Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif., Woo YJ; Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif; Department of Bioengineering, Stanford University, Stanford, Calif. Electronic address: joswoo@stanford.edu.

المصدر: The Journal of thoracic and cardiovascular surgery [J Thorac Cardiovasc Surg] 2019 Aug; Vol. 158 (2), pp. 392-403. Date of Electronic Publication: 2018 Nov 15.

نوع المنشور: Journal Article; Video-Audio Media

بيانات الدورية: Publisher: Mosby Country of Publication: United States NLM ID: 0376343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-685X (Electronic) Linking ISSN: 00225223 NLM ISO Abbreviation: J Thorac Cardiovasc Surg Subsets: MEDLINE

مواضيع طبية MeSH: Printing, Three-Dimensional*, Aorta/*surgery , Aortic Valve/*surgery, Animals ; Aorta/pathology ; Aorta/physiopathology ; Aortic Valve/pathology ; Aortic Valve/physiopathology ; Biomechanical Phenomena ; Coronary Circulation ; Echocardiography, Transesophageal ; Hemodynamics ; Models, Anatomic ; Sinus of Valsalva/pathology ; Sinus of Valsalva/physiopathology ; Sinus of Valsalva/surgery ; Swine ; Vascular Grafting/methods

المؤلفون: Kimura N; Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan., Futamura K; Department of Allergy and Clinical Immunology, National Research Institute for Child Health and Development, Tokyo, Japan., Arakawa M; Department of Cardiothoracic Surgery, Stanford University, School of Medicine, Stanford, CA, USA., Okada N; Department of Allergy and Clinical Immunology, National Research Institute for Child Health and Development, Tokyo, Japan., Emrich F; Department of Cardiothoracic Surgery, Stanford University, School of Medicine, Stanford, CA, USA., Okamura H; Department of Cardiothoracic Surgery, Stanford University, School of Medicine, Stanford, CA, USA., Sato T; Department of Cardiothoracic Surgery, Stanford University, School of Medicine, Stanford, CA, USA., Shudo Y; Department of Cardiothoracic Surgery, Stanford University, School of Medicine, Stanford, CA, USA., Koyano TK; Department of Cardiothoracic Surgery, Stanford University, School of Medicine, Stanford, CA, USA., Yamaguchi A; Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan., Adachi H; Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan., Matsuda A; Department of Allergy and Clinical Immunology, National Research Institute for Child Health and Development, Tokyo, Japan., Kawahito K; Division of Cardiovascular Surgery, Department of Surgery, Jichi Medical University, Shimotsuke, Japan., Matsumoto K; Department of Allergy and Clinical Immunology, National Research Institute for Child Health and Development, Tokyo, Japan., Fischbein MP; Department of Cardiothoracic Surgery, Stanford University, School of Medicine, Stanford, CA, USA.

المصدر: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery [Eur J Cardiothorac Surg] 2017 Oct 01; Vol. 52 (4), pp. 810-817.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: Germany NLM ID: 8804069 Publication Model: Print Cited Medium: Internet ISSN: 1873-734X (Electronic) Linking ISSN: 10107940 NLM ISO Abbreviation: Eur J Cardiothorac Surg Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Profiling* , Gene Expression Regulation*, Aortic Dissection/*genetics , Aortic Aneurysm, Thoracic/*genetics , MicroRNAs/*genetics , Tissue Inhibitor of Metalloproteinase-3/*genetics, Academic Medical Centers ; Analysis of Variance ; Aortic Dissection/physiopathology ; Aortic Aneurysm, Thoracic/physiopathology ; Cohort Studies ; Female ; Humans ; In Vitro Techniques ; Male ; Oligonucleotide Array Sequence Analysis ; Reproducibility of Results ; Statistics, Nonparametric

المؤلفون: Emrich FC; From the Department of Cardiothoracic Surgery (F.C.E., H.O., A.R.D., K.P., D.R.M., J.T.C., M.O.M., A.J.P., J.K.C., T.K.K, M.P.F.), Department of Cardiovascular Medicine (U.R.), Department of Pediatrics (J.K.H., C.M.A, M.R.), Department of Radiology (F.G.B.), and Department of Pathology (A.J.C.), Stanford University, CA; Department of Cardiothoracic Surgery, Heart Center, Leipzig University, Leipzig, Germany (F.C.E., K.P., D.R.M., F.W.M.); and Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan (H.O.)., Okamura H; From the Department of Cardiothoracic Surgery (F.C.E., H.O., A.R.D., K.P., D.R.M., J.T.C., M.O.M., A.J.P., J.K.C., T.K.K, M.P.F.), Department of Cardiovascular Medicine (U.R.), Department of Pediatrics (J.K.H., C.M.A, M.R.), Department of Radiology (F.G.B.), and Department of Pathology (A.J.C.), Stanford University, CA; Department of Cardiothoracic Surgery, Heart Center, Leipzig University, Leipzig, Germany (F.C.E., K.P., D.R.M., F.W.M.); and Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan (H.O.)., Dalal AR; From the Department of Cardiothoracic Surgery (F.C.E., H.O., A.R.D., K.P., D.R.M., J.T.C., M.O.M., A.J.P., J.K.C., T.K.K, M.P.F.), Department of Cardiovascular Medicine (U.R.), Department of Pediatrics (J.K.H., C.M.A, M.R.), Department of Radiology (F.G.B.), and Department of Pathology (A.J.C.), Stanford University, CA; Department of Cardiothoracic Surgery, Heart Center, Leipzig University, Leipzig, Germany (F.C.E., K.P., D.R.M., F.W.M.); and Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan (H.O.)., Penov K; From the Department of Cardiothoracic Surgery (F.C.E., H.O., A.R.D., K.P., D.R.M., J.T.C., M.O.M., A.J.P., J.K.C., T.K.K, M.P.F.), Department of Cardiovascular Medicine (U.R.), Department of Pediatrics (J.K.H., C.M.A, M.R.), Department of Radiology (F.G.B.), and Department of Pathology (A.J.C.), Stanford University, CA; Department of Cardiothoracic Surgery, Heart Center, Leipzig University, Leipzig, Germany (F.C.E., K.P., D.R.M., F.W.M.); and Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan (H.O.)., Merk DR; From the Department of Cardiothoracic Surgery (F.C.E., H.O., A.R.D., K.P., D.R.M., J.T.C., M.O.M., A.J.P., J.K.C., T.K.K, M.P.F.), Department of Cardiovascular Medicine (U.R.), Department of Pediatrics (J.K.H., C.M.A, M.R.), Department of Radiology (F.G.B.), and Department of Pathology (A.J.C.), Stanford University, CA; Department of Cardiothoracic Surgery, Heart Center, Leipzig University, Leipzig, Germany (F.C.E., K.P., D.R.M., F.W.M.); and Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan (H.O.)., Raaz U; From the Department of Cardiothoracic Surgery (F.C.E., H.O., A.R.D., K.P., D.R.M., J.T.C., M.O.M., A.J.P., J.K.C., T.K.K, M.P.F.), Department of Cardiovascular Medicine (U.R.), Department of Pediatrics (J.K.H., C.M.A, M.R.), Department of Radiology (F.G.B.), and Department of Pathology (A.J.C.), Stanford University, CA; Department of Cardiothoracic Surgery, Heart Center, Leipzig University, Leipzig, Germany (F.C.E., K.P., D.R.M., F.W.M.); and Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan (H.O.)., Hennigs JK; From the Department of Cardiothoracic Surgery (F.C.E., H.O., A.R.D., K.P., D.R.M., J.T.C., M.O.M., A.J.P., J.K.C., T.K.K, M.P.F.), Department of Cardiovascular Medicine (U.R.), Department of Pediatrics (J.K.H., C.M.A, M.R.), Department of Radiology (F.G.B.), and Department of Pathology (A.J.C.), Stanford University, CA; Department of Cardiothoracic Surgery, Heart Center, Leipzig University, Leipzig, Germany (F.C.E., K.P., D.R.M., F.W.M.); and Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan (H.O.)., Chin JT; From the Department of Cardiothoracic Surgery (F.C.E., H.O., A.R.D., K.P., D.R.M., J.T.C., M.O.M., A.J.P., J.K.C., T.K.K, M.P.F.), Department of Cardiovascular Medicine (U.R.), Department of Pediatrics (J.K.H., C.M.A, M.R.), Department of Radiology (F.G.B.), and Department of Pathology (A.J.C.), Stanford University, CA; Department of Cardiothoracic Surgery, Heart Center, Leipzig University, Leipzig, Germany (F.C.E., K.P., D.R.M., F.W.M.); and Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan (H.O.)., Miller MO; From the Department of Cardiothoracic Surgery (F.C.E., H.O., A.R.D., K.P., D.R.M., J.T.C., M.O.M., A.J.P., J.K.C., T.K.K, M.P.F.), Department of Cardiovascular Medicine (U.R.), Department of Pediatrics (J.K.H., C.M.A, M.R.), Department of Radiology (F.G.B.), and Department of Pathology (A.J.C.), Stanford University, CA; Department of Cardiothoracic Surgery, Heart Center, Leipzig University, Leipzig, Germany (F.C.E., K.P., D.R.M., F.W.M.); and Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan (H.O.)., Pedroza AJ; From the Department of Cardiothoracic Surgery (F.C.E., H.O., A.R.D., K.P., D.R.M., J.T.C., M.O.M., A.J.P., J.K.C., T.K.K, M.P.F.), Department of Cardiovascular Medicine (U.R.), Department of Pediatrics (J.K.H., C.M.A, M.R.), Department of Radiology (F.G.B.), and Department of Pathology (A.J.C.), Stanford University, CA; Department of Cardiothoracic Surgery, Heart Center, Leipzig University, Leipzig, Germany (F.C.E., K.P., D.R.M., F.W.M.); and Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan (H.O.)., Craig JK; From the Department of Cardiothoracic Surgery (F.C.E., H.O., A.R.D., K.P., D.R.M., J.T.C., M.O.M., A.J.P., J.K.C., T.K.K, M.P.F.), Department of Cardiovascular Medicine (U.R.), Department of Pediatrics (J.K.H., C.M.A, M.R.), Department of Radiology (F.G.B.), and Department of Pathology (A.J.C.), Stanford University, CA; Department of Cardiothoracic Surgery, Heart Center, Leipzig University, Leipzig, Germany (F.C.E., K.P., D.R.M., F.W.M.); and Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan (H.O.)., Koyano TK; From the Department of Cardiothoracic Surgery (F.C.E., H.O., A.R.D., K.P., D.R.M., J.T.C., M.O.M., A.J.P., J.K.C., T.K.K, M.P.F.), Department of Cardiovascular Medicine (U.R.), Department of Pediatrics (J.K.H., C.M.A, M.R.), Department of Radiology (F.G.B.), and Department of Pathology (A.J.C.), Stanford University, CA; Department of Cardiothoracic Surgery, Heart Center, Leipzig University, Leipzig, Germany (F.C.E., K.P., D.R.M., F.W.M.); and Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan (H.O.)., Blankenberg FG; From the Department of Cardiothoracic Surgery (F.C.E., H.O., A.R.D., K.P., D.R.M., J.T.C., M.O.M., A.J.P., J.K.C., T.K.K, M.P.F.), Department of Cardiovascular Medicine (U.R.), Department of Pediatrics (J.K.H., C.M.A, M.R.), Department of Radiology (F.G.B.), and Department of Pathology (A.J.C.), Stanford University, CA; Department of Cardiothoracic Surgery, Heart Center, Leipzig University, Leipzig, Germany (F.C.E., K.P., D.R.M., F.W.M.); and Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan (H.O.)., Connolly AJ; From the Department of Cardiothoracic Surgery (F.C.E., H.O., A.R.D., K.P., D.R.M., J.T.C., M.O.M., A.J.P., J.K.C., T.K.K, M.P.F.), Department of Cardiovascular Medicine (U.R.), Department of Pediatrics (J.K.H., C.M.A, M.R.), Department of Radiology (F.G.B.), and Department of Pathology (A.J.C.), Stanford University, CA; Department of Cardiothoracic Surgery, Heart Center, Leipzig University, Leipzig, Germany (F.C.E., K.P., D.R.M., F.W.M.); and Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan (H.O.)., Mohr FW; From the Department of Cardiothoracic Surgery (F.C.E., H.O., A.R.D., K.P., D.R.M., J.T.C., M.O.M., A.J.P., J.K.C., T.K.K, M.P.F.), Department of Cardiovascular Medicine (U.R.), Department of Pediatrics (J.K.H., C.M.A, M.R.), Department of Radiology (F.G.B.), and Department of Pathology (A.J.C.), Stanford University, CA; Department of Cardiothoracic Surgery, Heart Center, Leipzig University, Leipzig, Germany (F.C.E., K.P., D.R.M., F.W.M.); and Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan (H.O.)., Alvira CM; From the Department of Cardiothoracic Surgery (F.C.E., H.O., A.R.D., K.P., D.R.M., J.T.C., M.O.M., A.J.P., J.K.C., T.K.K, M.P.F.), Department of Cardiovascular Medicine (U.R.), Department of Pediatrics (J.K.H., C.M.A, M.R.), Department of Radiology (F.G.B.), and Department of Pathology (A.J.C.), Stanford University, CA; Department of Cardiothoracic Surgery, Heart Center, Leipzig University, Leipzig, Germany (F.C.E., K.P., D.R.M., F.W.M.); and Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan (H.O.)., Rabinovitch M; From the Department of Cardiothoracic Surgery (F.C.E., H.O., A.R.D., K.P., D.R.M., J.T.C., M.O.M., A.J.P., J.K.C., T.K.K, M.P.F.), Department of Cardiovascular Medicine (U.R.), Department of Pediatrics (J.K.H., C.M.A, M.R.), Department of Radiology (F.G.B.), and Department of Pathology (A.J.C.), Stanford University, CA; Department of Cardiothoracic Surgery, Heart Center, Leipzig University, Leipzig, Germany (F.C.E., K.P., D.R.M., F.W.M.); and Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan (H.O.)., Fischbein MP; From the Department of Cardiothoracic Surgery (F.C.E., H.O., A.R.D., K.P., D.R.M., J.T.C., M.O.M., A.J.P., J.K.C., T.K.K, M.P.F.), Department of Cardiovascular Medicine (U.R.), Department of Pediatrics (J.K.H., C.M.A, M.R.), Department of Radiology (F.G.B.), and Department of Pathology (A.J.C.), Stanford University, CA; Department of Cardiothoracic Surgery, Heart Center, Leipzig University, Leipzig, Germany (F.C.E., K.P., D.R.M., F.W.M.); and Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan (H.O.). mfischbe@stanford.edu.

المصدر: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2015 Jan; Vol. 35 (1), pp. 146-54. Date of Electronic Publication: 2014 Oct 30.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505803 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4636 (Electronic) Linking ISSN: 10795642 NLM ISO Abbreviation: Arterioscler Thromb Vasc Biol Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis*/drug effects , Vascular Remodeling*/drug effects, Aortic Aneurysm/*etiology , Caspases/*metabolism , Cell Membrane/*enzymology , Marfan Syndrome/*complications , Muscle, Smooth, Vascular/*enzymology , Myocytes, Smooth Muscle/*enzymology, Animals ; Aorta/enzymology ; Aortic Aneurysm/diagnosis ; Aortic Aneurysm/enzymology ; Aortic Aneurysm/genetics ; Aortic Aneurysm/prevention & control ; Autoradiography ; Caspase Inhibitors/pharmacology ; Cells, Cultured ; Disease Models, Animal ; Disease Progression ; Elastin/metabolism ; Female ; Fibrillin-1 ; Fibrillins ; Fluorescent Antibody Technique ; Male ; Marfan Syndrome/genetics ; Mice, Inbred C57BL ; Mice, Mutant Strains ; Microfilament Proteins/genetics ; Microscopy, Electron, Scanning ; Muscle, Smooth, Vascular/diagnostic imaging ; Muscle, Smooth, Vascular/drug effects ; Muscle, Smooth, Vascular/ultrastructure ; Mutation ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/ultrastructure ; Time Factors ; Tomography, Emission-Computed, Single-Photon