المؤلفون: Pokorna, P, Michalickova, D, Voller, S, Hronova, K, Tibboel, D, Slanar, O, Krekels, EH

المصدر: Minerva pediatrics. 74(2):107-115

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:149602960

المؤلفون: Krekels EH, Tibboel D, Danhof M, Knibbe CA, Krekels, Elke H J, Tibboel, Dick, Danhof, Meindert, Knibbe, Catherijne A J

المصدر: Clinical Pharmacokinetics; 2012, Vol. 51 Issue 11, p695-709, 15p

المؤلفون: Evelyne Jacqz-Aigrain, Dick Tibboel, Hannah Green, John N. van den Anker, Oscar Della Pasqua, Massimo Cella, Ron H.N. van Schaik, Achille Iolascon, Elke H. J. Krekels, Gijs W. E. Santen, Paola Baiardi, Catherijne A. J. Knibbe, Diana M. Gibb, Katharine Cheng

المساهمون: Krekels, Eh, van den Anker, Jn, Baiardi, P, Cella, M, Cheng, Ky, Gibb, Dm, Green, H, Iolascon, Achille, Jacqz Aigrain, Em, Knibbe, Ca, Santen, Gw, van Schaik, Rh, Tibboel, D, Della Pasqua, O. E.

مصطلحات موضوعية: Research design, MEDLINE, Pharmacology, Drug response, Medicine, Humans, Pharmacology (medical), Treatment effect, Dosing, Medical prescription, Child, Drug Labeling, Clinical Trials as Topic, Polymorphism, Genetic, Dose-Response Relationship, Drug, business.industry, Age Factors, General Medicine, ACUTE LYMPHOBLASTIC-LEUKEMIA, ORAL-CONTRACEPTIVES, POPULATION STRATIFICATION, MYOCARDIAL-INFARCTION, CLINICAL-TRIALS, CANDIDATE-GENE, RISK, ASSOCIATION, CHILDREN, POLYMORPHISM, Risk analysis (engineering), Drug development, Pharmaceutical Preparations, Pharmacogenetics, Research Design, Drug Design, business

وصف الملف: ELETTRONICO

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef49ef4f842478dd7fcd36afe497d9a
http://hdl.handle.net/11588/474401

المؤلفون: van Rongen A; Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Krekels EH; Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Calvier EA; Sanofi Pharmacokinetics-Dynamics and Metabolism (PKDM), Translational Medicine and Early Development, Sanofi R&d, Montpellier, France., de Wildt SN; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands.; Intensive Care and Department of Pediatric Surgery, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands., Vermeulen A; Laboratory of Medical Biochemistry and Clinical Analysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.; Janssen R&D, a Division of Janssen Pharmaceutica Nv, Beerse, Belgium., Knibbe CA; Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.; Department of Clinical Pharmacy, St. Antonius Hospital, Nieuwegein, The Netherlands.

المصدر: Expert opinion on drug metabolism & toxicology [Expert Opin Drug Metab Toxicol] 2022 Feb; Vol. 18 (2), pp. 99-113. Date of Electronic Publication: 2022 Feb 25.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101228422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7607 (Electronic) Linking ISSN: 17425255 NLM ISO Abbreviation: Expert Opin Drug Metab Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Models, Biological* , Off-Label Use*, Adult ; Child ; Drug Elimination Routes ; Humans ; Metabolic Clearance Rate ; Pharmacokinetics

المؤلفون: Goulooze SC; From the Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands., Krekels EH; From the Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands., Saleh MA; From the Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands., Ahlers SJ; Department of Clinical Pharmacy, Rijnstate Hospital, Arnhem, the Netherlands., Välitalo PA; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.; Assessment of Medicinal Products Department, Finnish Medicines Agency, Kuopio, Finland., van Dongen EP; Department of Anesthesiology and Intensive Care and Pain Management, St. Antonius Hospital, Nieuwegein, the Netherlands., van Schaik RH; Department of Clinical Chemistry, Erasmus Medical Center, Rotterdam, the Netherlands., Hankemeier T; From the Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands., Tibboel D; Intensive Care and Department of Pediatric Surgery, Sophia's Children's Hospital, Rotterdam, the Netherlands., Knibbe CAJ; From the Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands.; Department of Clinical Pharmacy, St. Antonius Hospital, Nieuwegein, the Netherlands.

المصدر: Anesthesia and analgesia [Anesth Analg] 2021 Mar 01; Vol. 132 (3), pp. 726-734.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 1310650 Publication Model: Print Cited Medium: Internet ISSN: 1526-7598 (Electronic) Linking ISSN: 00032999 NLM ISO Abbreviation: Anesth Analg Subsets: MEDLINE

مواضيع طبية MeSH: Models, Theoretical* , Pain Management*, Analgesics, Opioid/*pharmacokinetics , Cardiac Surgical Procedures/*adverse effects , Morphine/*pharmacokinetics , Pain, Postoperative/*drug therapy , Pain, Postoperative/*etiology, Aged ; Analgesics, Opioid/administration & dosage ; Drug Administration Schedule ; Female ; Humans ; Male ; Middle Aged ; Morphine/administration & dosage ; Pain, Postoperative/diagnosis ; Risk Assessment ; Risk Factors ; Treatment Outcome

المؤلفون: Russo FM; a Cluster Woman and Child, Department of Development and Regeneration, Biomedical Sciences, KU Leuven , Leuven , Belgium.; b Department of Obstetrics and Gynecology , University Hospitals Leuven , Leuven , Belgium., Mian P; c Intensive Care and Department of Paediatric Surgery , Erasmus MC Sophia Children's Hospital , Rotterdam , The Netherlands., Krekels EH; d Division of Pharmacology , Leiden Academic Centre for Drug Research, Leiden University , Leiden , The Netherlands , and., Van Calsteren K; a Cluster Woman and Child, Department of Development and Regeneration, Biomedical Sciences, KU Leuven , Leuven , Belgium.; b Department of Obstetrics and Gynecology , University Hospitals Leuven , Leuven , Belgium., Tibboel D; c Intensive Care and Department of Paediatric Surgery , Erasmus MC Sophia Children's Hospital , Rotterdam , The Netherlands., Deprest J; a Cluster Woman and Child, Department of Development and Regeneration, Biomedical Sciences, KU Leuven , Leuven , Belgium.; b Department of Obstetrics and Gynecology , University Hospitals Leuven , Leuven , Belgium.; e Department of Obstetrics and Gynecology , Institute of Women's Health, University College London , London , UK., Allegaert K; a Cluster Woman and Child, Department of Development and Regeneration, Biomedical Sciences, KU Leuven , Leuven , Belgium.; c Intensive Care and Department of Paediatric Surgery , Erasmus MC Sophia Children's Hospital , Rotterdam , The Netherlands.

المصدر: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2019 Jan; Vol. 49 (1), pp. 98-105. Date of Electronic Publication: 2018 Jan 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1366-5928 (Electronic) Linking ISSN: 00498254 NLM ISO Abbreviation: Xenobiotica Subsets: MEDLINE

مواضيع طبية MeSH: Sildenafil Citrate/*pharmacokinetics, Animals ; Female ; Models, Biological ; Pregnancy ; Rabbits ; Sildenafil Citrate/metabolism ; Vasodilator Agents/pharmacokinetics

المؤلفون: Allegaert K; Intensive Care and Department of Pediatric Surgery, Erasmus MC Sophia Children's Hospital, Rotterdam, the Netherlands; Department of Development and Regeneration KU Leuven, Leuven, Belgium., Simons SHP; Department of Pediatrics, Division of Neonatology, Erasmus MC Sophia Children's Hospital, Rotterdam, the Netherlands. Electronic address: s.simons@erasmusmc.nl., Tibboel D; Intensive Care and Department of Pediatric Surgery, Erasmus MC Sophia Children's Hospital, Rotterdam, the Netherlands., Krekels EH; Division of Pharmacology, Leiden Academic Center for Drug Research, Leiden, the Netherlands., Knibbe CA; Division of Pharmacology, Leiden Academic Center for Drug Research, Leiden, the Netherlands; Department of Clinical Pharmacy, St. Antonius Hospital, Nieuwegein, the Netherlands., van den Anker JN; Intensive Care and Department of Pediatric Surgery, Erasmus MC Sophia Children's Hospital, Rotterdam, the Netherlands; Division of Clinical Pharmacology, Children's National Health System, Washington, DC, USA; Division of Pediatric Pharmacology and Pharmacometrics, University of Basel Children's Hospital, Basel, Switzerland.

المصدر: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2017 Nov 15; Vol. 109S, pp. S27-S31. Date of Electronic Publication: 2017 May 12.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Science B.V Country of Publication: Netherlands NLM ID: 9317982 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0720 (Electronic) Linking ISSN: 09280987 NLM ISO Abbreviation: Eur J Pharm Sci Subsets: MEDLINE

مواضيع طبية MeSH: Pharmaceutical Preparations/*administration & dosage , Precision Medicine/*methods, Child ; Dose-Response Relationship, Drug ; Humans ; Infant ; Infant, Newborn ; Models, Biological ; Pharmacogenetics/methods ; Pharmacokinetics

المؤلفون: Välitalo PA; Division of Pharmacology, Leiden University, Leiden, The Netherlands., Krekels EH; Division of Pharmacology, Leiden University, Leiden, The Netherlands., van Dijk M; Intensive Care and Department of Pediatric Surgery Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands.; Department of Pediatrics, Division of Neonatology, Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands., Simons S; Department of Pediatrics, Division of Neonatology, Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands., Tibboel D; Intensive Care and Department of Pediatric Surgery Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands., Knibbe CA; Division of Pharmacology, Leiden University, Leiden, The Netherlands.; Intensive Care and Department of Pediatric Surgery Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands.; Department of Clinical Pharmacy, St Antonius Hospital, Nieuwegein, The Netherlands.

المصدر: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2017 Apr; Vol. 6 (4), pp. 239-248. Date of Electronic Publication: 2017 Jan 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Analgesics, Opioid/*pharmacokinetics , Intubation, Intratracheal/*methods , Morphine/*pharmacokinetics , Pain/*drug therapy , Respiration, Artificial/*adverse effects , Respiration, Artificial/*methods, Analgesics, Opioid/administration & dosage ; Humans ; Infant, Newborn ; Infant, Premature ; Intubation, Intratracheal/adverse effects ; Morphine/administration & dosage ; Pain/etiology ; Pain/metabolism ; Pain Measurement ; Randomized Controlled Trials as Topic ; Treatment Outcome

المؤلفون: Calvier EA; Division of Pharmacology, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Gorlaeus Laboratories, Einsteinweg, 552333 CC, Leiden, The Netherlands., Krekels EH; Division of Pharmacology, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Gorlaeus Laboratories, Einsteinweg, 552333 CC, Leiden, The Netherlands., Välitalo PA; Division of Pharmacology, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Gorlaeus Laboratories, Einsteinweg, 552333 CC, Leiden, The Netherlands., Rostami-Hodjegan A; Manchester Pharmacy School, University of Manchester, Manchester, UK., Tibboel D; Intensive Care and Department of Pediatric Surgery, Erasmus University Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands., Danhof M; Division of Pharmacology, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Gorlaeus Laboratories, Einsteinweg, 552333 CC, Leiden, The Netherlands., Knibbe CA; Division of Pharmacology, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Gorlaeus Laboratories, Einsteinweg, 552333 CC, Leiden, The Netherlands. c.knibbe@antoniusziekenhuis.nl.; Department of Clinical Pharmacy, St. Antonius Hospital, Nieuwegein, The Netherlands. c.knibbe@antoniusziekenhuis.nl.

المصدر: Clinical pharmacokinetics [Clin Pharmacokinet] 2017 Mar; Vol. 56 (3), pp. 273-285.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print Cited Medium: Internet ISSN: 1179-1926 (Electronic) Linking ISSN: 03125963 NLM ISO Abbreviation: Clin Pharmacokinet Subsets: MEDLINE

مواضيع طبية MeSH: Models, Biological*, Body Weight/*physiology , Pharmaceutical Preparations/*blood, Adolescent ; Body Weight/drug effects ; Child ; Child, Preschool ; Humans ; Infant ; Infant, Newborn ; Metabolic Clearance Rate/drug effects ; Metabolic Clearance Rate/physiology ; Pharmaceutical Preparations/administration & dosage

المؤلفون: Novakovic AM; Department of Pharmaceutical Biosciences, Uppsala University, Box 591, 751 24, Uppsala, Sweden. ana.kalezic@farmbio.uu.se., Krekels EH; Department of Pharmaceutical Biosciences, Uppsala University, Box 591, 751 24, Uppsala, Sweden.; Division of Pharmacology, Leiden Academic Centre of Drug Research, Leiden University, Leiden, Netherlands., Munafo A; Merck Institute for Pharmacometrics, Merck Serono, Lausanne, Switzerland., Ueckert S; Department of Pharmaceutical Biosciences, Uppsala University, Box 591, 751 24, Uppsala, Sweden., Karlsson MO; Department of Pharmaceutical Biosciences, Uppsala University, Box 591, 751 24, Uppsala, Sweden.

المصدر: The AAPS journal [AAPS J] 2017 Jan; Vol. 19 (1), pp. 172-179. Date of Electronic Publication: 2016 Sep 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association of Pharmaceutical Scientists Country of Publication: United States NLM ID: 101223209 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1550-7416 (Electronic) Linking ISSN: 15507416 NLM ISO Abbreviation: AAPS J Subsets: MEDLINE

مواضيع طبية MeSH: Disability Evaluation* , Models, Theoretical* , Severity of Illness Index*, Multiple Sclerosis, Relapsing-Remitting/*diagnosis, Cladribine/therapeutic use ; Clinical Trials, Phase III as Topic ; Disease Progression ; Humans ; Immunosuppressive Agents/therapeutic use ; Logistic Models ; Multiple Sclerosis, Relapsing-Remitting/drug therapy