المؤلفون: Borrelli C; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Roberts M; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Eletto D; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Hussherr MD; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Fazilaty H; Department of Molecular Life Sciences, University of Zurich, Zurich, Switzerland., Valenta T; Department of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.; Laboratory of Cell and Developmental Biology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic., Lafzi A; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Kretz JA; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Guido Vinzoni E; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Karakatsani A; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Adivarahan S; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Mannhart A; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Kimura S; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Meijs A; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Baccouche Mhamedi F; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Acar IE; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Handler K; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Ficht X; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Platt RJ; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Piscuoglio S; IRCCS Humanitas Research Hospital, Milan, Italy.; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland., Moor AE; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland. andreas.moor@bsse.ethz.ch.

المصدر: Nature [Nature] 2024 Aug; Vol. 632 (8024), pp. 411-418. Date of Electronic Publication: 2024 Jul 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: CRISPR-Cas Systems*/genetics , Hepatocytes*/metabolism , Hepatocytes*/cytology , Hepatocytes*/pathology , Liver*/cytology , Liver*/metabolism , Liver*/pathology , Liver Neoplasms*/drug therapy , Liver Neoplasms*/metabolism , Liver Neoplasms*/pathology , Liver Neoplasms*/prevention & control , Liver Neoplasms*/secondary , Neoplasm Metastasis*/drug therapy , Neoplasm Metastasis*/pathology , Neoplasm Metastasis*/prevention & control , Nerve Tissue Proteins*/antagonists & inhibitors , Nerve Tissue Proteins*/metabolism, Animals ; Female ; Humans ; Male ; Mice ; Cell Line, Tumor ; Colorectal Neoplasms/pathology ; Colorectal Neoplasms/metabolism ; Disease Models, Animal ; DNA Transposable Elements ; Fluorescence ; Kruppel-Like Factor 4/metabolism ; Melanoma/metabolism ; Melanoma/pathology ; Pancreatic Neoplasms/metabolism ; Pancreatic Neoplasms/pathology ; Semaphorins/antagonists & inhibitors ; Semaphorins/metabolism

المؤلفون: Renz PF; Institute for Regenerative Medicine (IREM), University of Zurich, Schlieren-Zurich, Switzerland., Ghoshdastider U; Institute for Regenerative Medicine (IREM), University of Zurich, Schlieren-Zurich, Switzerland., Baghai Sain S; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Valdivia-Francia F; Institute for Regenerative Medicine (IREM), University of Zurich, Schlieren-Zurich, Switzerland.; Life Science Zurich Graduate School, Molecular Life Science Program, University of Zurich and ETH Zurich, Zurich, Switzerland., Khandekar A; Max Perutz Labs, Vienna BioCenter Campus (VBC), Vienna, Austria.; Center for Molecular Biology, Department of Microbiology, Immunobiology and Genetics, University of Vienna, Vienna, Austria., Ormiston M; Institute for Regenerative Medicine (IREM), University of Zurich, Schlieren-Zurich, Switzerland., Bernasconi M; Institute for Regenerative Medicine (IREM), University of Zurich, Schlieren-Zurich, Switzerland., Duré C; Institute for Regenerative Medicine (IREM), University of Zurich, Schlieren-Zurich, Switzerland.; Life Science Zurich Graduate School, Molecular Life Science Program, University of Zurich and ETH Zurich, Zurich, Switzerland., Kretz JA; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Lee M; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Hyams K; Institute for Regenerative Medicine (IREM), University of Zurich, Schlieren-Zurich, Switzerland., Forny M; Institute for Regenerative Medicine (IREM), University of Zurich, Schlieren-Zurich, Switzerland., Pohly M; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Ficht X; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Ellis SJ; Max Perutz Labs, Vienna BioCenter Campus (VBC), Vienna, Austria.; Center for Molecular Biology, Department of Microbiology, Immunobiology and Genetics, University of Vienna, Vienna, Austria., Moor AE; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland. andreas.moor@bsse.ethz.ch., Sendoel A; Institute for Regenerative Medicine (IREM), University of Zurich, Schlieren-Zurich, Switzerland. ataman.sendoel@uzh.ch.

المصدر: Nature [Nature] 2024 Aug; Vol. 632 (8024), pp. 419-428. Date of Electronic Publication: 2024 Jul 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Squamous Cell*/genetics , Carcinoma, Squamous Cell*/pathology , Cell Transformation, Neoplastic*/genetics , Cell Transformation, Neoplastic*/pathology , Clonal Evolution*/genetics , Clone Cells*/cytology , Clone Cells*/metabolism , Clone Cells*/pathology , CRISPR-Cas Systems*/genetics , Single-Cell Analysis*/methods , Tumor Necrosis Factors*/genetics , Tumor Necrosis Factors*/metabolism, Animals ; Female ; Humans ; Male ; Mice ; Clustered Regularly Interspaced Short Palindromic Repeats/genetics ; Epithelial-Mesenchymal Transition/genetics ; Gene Expression Regulation, Neoplastic ; Macrophages/metabolism ; Mutation ; Neoplasm Invasiveness/genetics ; Receptors, Tumor Necrosis Factor, Type I/genetics ; Receptors, Tumor Necrosis Factor, Type I/metabolism ; Signal Transduction/genetics ; Transcriptome/genetics ; Autocrine Communication ; Survival Analysis

المؤلفون: Lafzi A; Roche Pharma Research and Early Development, Immunology Infectious Diseases and Ophthalmology Discovery and Translational Area, Grenzacherstrasse 124, 4070, Basel, Switzerland.; Department of Biosystems Science and Engineering, ETH Zürich, Mattenstrasse 26, 4058, Basel, Switzerland., Borrelli C; Department of Biosystems Science and Engineering, ETH Zürich, Mattenstrasse 26, 4058, Basel, Switzerland., Baghai Sain S; Department of Biosystems Science and Engineering, ETH Zürich, Mattenstrasse 26, 4058, Basel, Switzerland., Bach K; Department of Biosystems Science and Engineering, ETH Zürich, Mattenstrasse 26, 4058, Basel, Switzerland., Kretz JA; Department of Biosystems Science and Engineering, ETH Zürich, Mattenstrasse 26, 4058, Basel, Switzerland., Handler K; Department of Biosystems Science and Engineering, ETH Zürich, Mattenstrasse 26, 4058, Basel, Switzerland., Regan-Komito D; Roche Pharma Research and Early Development, Immunology Infectious Diseases and Ophthalmology Discovery and Translational Area, Grenzacherstrasse 124, 4070, Basel, Switzerland., Ficht X; Department of Biosystems Science and Engineering, ETH Zürich, Mattenstrasse 26, 4058, Basel, Switzerland., Frei A; Roche Pharma Research and Early Development, Immunology Infectious Diseases and Ophthalmology Discovery and Translational Area, Grenzacherstrasse 124, 4070, Basel, Switzerland., Moor A; Department of Biosystems Science and Engineering, ETH Zürich, Mattenstrasse 26, 4058, Basel, Switzerland. andreas.moor@bsse.ethz.ch.

المصدر: Molecular systems biology [Mol Syst Biol] 2024 Feb; Vol. 20 (2), pp. 98-119. Date of Electronic Publication: 2024 Jan 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Blackwell Country of Publication: England NLM ID: 101235389 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-4292 (Electronic) Linking ISSN: 17444292 NLM ISO Abbreviation: Mol Syst Biol Subsets: MEDLINE

مواضيع طبية MeSH: Colitis, Ulcerative*/genetics , Colitis, Ulcerative*/metabolism, Humans ; Gene Expression Profiling/methods ; Transcriptome/genetics ; Inflammation/genetics

المؤلفون: Chaker Z; Biozentrum, University of Basel, 4056 Basel, Switzerland., Segalada C; Biozentrum, University of Basel, 4056 Basel, Switzerland., Kretz JA; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland., Acar IE; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland., Delgado AC; Biozentrum, University of Basel, 4056 Basel, Switzerland., Crotet V; Biozentrum, University of Basel, 4056 Basel, Switzerland., Moor AE; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland., Doetsch F; Biozentrum, University of Basel, 4056 Basel, Switzerland.

المصدر: Science (New York, N.Y.) [Science] 2023 Nov 24; Vol. 382 (6673), pp. 958-963. Date of Electronic Publication: 2023 Nov 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Pregnancy*/physiology , Interneurons*/cytology , Interneurons*/physiology , Lateral Ventricles*/cytology , Lateral Ventricles*/growth & development , Neurogenesis*/physiology , Neuronal Plasticity* , Olfactory Bulb*/cytology , Olfactory Bulb*/growth & development , Olfactory Bulb*/metabolism , Smell* , Maternal Behavior*/physiology, Animals ; Female ; Mice ; Adult Stem Cells/physiology ; Neural Stem Cells/physiology ; Transcriptome