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المؤلفون: Conceição RAD; Laboratory of Molecular Modeling & QSAR (ModMolQSAR), Faculty of Pharmacy, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; Laboratory of Organic Synthesis and Medicinal Chemistry (LaSOQuiM), Faculty of Pharmacy, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., von Ranke N; Laboratory of Molecular Modeling & QSAR (ModMolQSAR), Faculty of Pharmacy, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Azevedo L; Laboratory of Molecular Diversity and Medicinal Chemistry (LaDMol-QM), Institute of Chemistry, Federal Rural University of Rio de Janeiro, Seropédica, Brazil., Franco D; Laboratory of Molecular Diversity and Medicinal Chemistry (LaDMol-QM), Institute of Chemistry, Federal Rural University of Rio de Janeiro, Seropédica, Brazil., Nadur NF; Laboratory of Molecular Diversity and Medicinal Chemistry (LaDMol-QM), Institute of Chemistry, Federal Rural University of Rio de Janeiro, Seropédica, Brazil., Kummerle AE; Laboratory of Molecular Diversity and Medicinal Chemistry (LaDMol-QM), Institute of Chemistry, Federal Rural University of Rio de Janeiro, Seropédica, Brazil., Barbosa MLC; Laboratory of Organic Synthesis and Medicinal Chemistry (LaSOQuiM), Faculty of Pharmacy, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Souza AMT; Laboratory of Molecular Modeling & QSAR (ModMolQSAR), Faculty of Pharmacy, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

المصدر: Journal of cellular biochemistry [J Cell Biochem] 2023 Nov; Vol. 124 (11), pp. 1734-1748. Date of Electronic Publication: 2023 Oct 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8205768 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4644 (Electronic) Linking ISSN: 07302312 NLM ISO Abbreviation: J Cell Biochem Subsets: MEDLINE

مواضيع طبية MeSH: Butyrylcholinesterase*/metabolism , Butyrylcholinesterase*/therapeutic use , Alzheimer Disease*/drug therapy , Alzheimer Disease*/metabolism, Humans ; Cholinesterase Inhibitors/pharmacology ; Cholinesterase Inhibitors/chemistry ; Cholinesterase Inhibitors/therapeutic use ; Acetylcholinesterase/metabolism ; Piperidines/pharmacology ; Piperidines/therapeutic use ; Structure-Activity Relationship ; Molecular Docking Simulation

المؤلفون: de Almeida PSVB; Instituto de Química, Universidade Federal Rural do Rio de Janeiro, BR 465 Km 7, 23890-000, Seropédica, RJ, Brazil. amandanevess@ufrrj.br., de Arruda HJ; Instituto de Química, Universidade Federal Rural do Rio de Janeiro, BR 465 Km 7, 23890-000, Seropédica, RJ, Brazil. amandanevess@ufrrj.br., Sousa GLS; Instituto de Química, Universidade Federal Rural do Rio de Janeiro, BR 465 Km 7, 23890-000, Seropédica, RJ, Brazil. amandanevess@ufrrj.br., Ribeiro FV; Instituto de Química, Universidade Federal Rural do Rio de Janeiro, BR 465 Km 7, 23890-000, Seropédica, RJ, Brazil. amandanevess@ufrrj.br., de Azevedo-França JA; Instituto de Ciências Exatas, Departamento de Química, Universidade Federal de Juiz de Fora, MG, Brazil., Ferreira LA; Instituto de Química, Universidade Federal Rural do Rio de Janeiro, BR 465 Km 7, 23890-000, Seropédica, RJ, Brazil. amandanevess@ufrrj.br., Guedes GP; Instituto de Química, Universidade Federal Fluminense, Niterói, RJ, Brazil., Silva H; Instituto de Ciências Exatas, Departamento de Química, Universidade Federal de Minas Gerais, MG, Brazil., Kummerle AE; Instituto de Química, Universidade Federal Rural do Rio de Janeiro, BR 465 Km 7, 23890-000, Seropédica, RJ, Brazil. amandanevess@ufrrj.br., Neves AP; Instituto de Química, Universidade Federal Rural do Rio de Janeiro, BR 465 Km 7, 23890-000, Seropédica, RJ, Brazil. amandanevess@ufrrj.br.

المصدر: Dalton transactions (Cambridge, England : 2003) [Dalton Trans] 2021 Oct 26; Vol. 50 (41), pp. 14908-14919. Date of Electronic Publication: 2021 Oct 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101176026 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-9234 (Electronic) Linking ISSN: 14779226 NLM ISO Abbreviation: Dalton Trans

مواضيع طبية MeSH: DNA*/chemistry , DNA*/metabolism , Ruthenium*/chemistry , Ruthenium*/pharmacology , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Coumarins*/chemistry , Coumarins*/pharmacology , Coordination Complexes*/chemistry , Coordination Complexes*/pharmacology , Coordination Complexes*/chemical synthesis, Ligands ; Humans ; Animals ; Cell Line, Tumor ; Drug Screening Assays, Antitumor ; Molecular Structure ; 2,2'-Dipyridyl/chemistry ; 2,2'-Dipyridyl/pharmacology ; Cell Proliferation/drug effects ; Molecular Docking Simulation

المؤلفون: Pereira TM; Laboratorio de Diversidade Molecular e Quimica Medicinal (LaDMol-QM, Molecular Diversity and Medicinal Chemistry Laboratory), Departament of Chemistry, Universidade Federal Rural do Rio de Janeiro, Seropedica, Rio de Janeiro, 239897-000, Brazil., Franco DP; Laboratorio de Diversidade Molecular e Quimica Medicinal (LaDMol-QM, Molecular Diversity and Medicinal Chemistry Laboratory), Departament of Chemistry, Universidade Federal Rural do Rio de Janeiro, Seropedica, Rio de Janeiro, 239897-000, Brazil., Vitorio F; Laboratorio de Diversidade Molecular e Quimica Medicinal (LaDMol-QM, Molecular Diversity and Medicinal Chemistry Laboratory), Departament of Chemistry, Universidade Federal Rural do Rio de Janeiro, Seropedica, Rio de Janeiro, 239897-000, Brazil., Kummerle AE; Laboratorio de Diversidade Molecular e Quimica Medicinal (LaDMol-QM, Molecular Diversity and Medicinal Chemistry Laboratory), Departament of Chemistry, Universidade Federal Rural do Rio de Janeiro, Seropedica, Rio de Janeiro, 239897-000, Brazil.

المصدر: Current topics in medicinal chemistry [Curr Top Med Chem] 2018; Vol. 18 (2), pp. 124-148.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101119673 Publication Model: Print Cited Medium: Internet ISSN: 1873-4294 (Electronic) Linking ISSN: 15680266 NLM ISO Abbreviation: Curr Top Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Coumarins/*pharmacology, Anti-Infective Agents/chemical synthesis ; Anti-Infective Agents/chemistry ; Anti-Infective Agents/pharmacology ; Anti-Inflammatory Agents, Non-Steroidal/chemical synthesis ; Anti-Inflammatory Agents, Non-Steroidal/chemistry ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Anticoagulants/chemical synthesis ; Anticoagulants/chemistry ; Anticoagulants/pharmacology ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Antioxidants/chemical synthesis ; Antioxidants/chemistry ; Antioxidants/pharmacology ; Chemistry, Pharmaceutical ; Coumarins/chemical synthesis ; Coumarins/chemistry ; Humans ; Hypoglycemic Agents/chemical synthesis ; Hypoglycemic Agents/chemistry ; Hypoglycemic Agents/pharmacology ; Molecular Structure ; Neuroprotective Agents/chemical synthesis ; Neuroprotective Agents/chemistry ; Neuroprotective Agents/pharmacology

المؤلفون: Marques EB; Laboratory of Experimental Pharmacology, Department of Physiology and Pharmacology, Fluminense Federal University, Niterói, RJ, Brazil., Motta NA; Laboratory of Experimental Pharmacology, Department of Physiology and Pharmacology, Fluminense Federal University, Niterói, RJ, Brazil., Kummerle AE; Department of Chemistry, Institute of Exact Sciences, Rural Federal University of Rio de Janeiro UFRRJ, Seropédica, R.J., Brazil., Fraga CA; Laboratory of Evaluation and Synthesis of Bioactive Compounds (LASSBio), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, R.J., Brazil., Barreiro EJ; Laboratory of Evaluation and Synthesis of Bioactive Compounds (LASSBio), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, R.J., Brazil., Brito FC; Laboratory of Experimental Pharmacology, Department of Physiology and Pharmacology, Fluminense Federal University, Niterói, RJ, Brazil., Scaramello CB; Laboratory of Experimental Pharmacology, Department of Physiology and Pharmacology, Fluminense Federal University, Niterói, RJ, Brazil. Electronic address: christiannebretas@vm.uff.br.

المصدر: International journal of cardiology [Int J Cardiol] 2015 Dec 15; Vol. 201, pp. 282-4. Date of Electronic Publication: 2015 Aug 13.

نوع المنشور: Letter; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8200291 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1874-1754 (Electronic) Linking ISSN: 01675273 NLM ISO Abbreviation: Int J Cardiol Subsets: MEDLINE

مواضيع طبية MeSH: Calcium-Transporting ATPases/*drug effects , Hydrazones/*pharmacology , Hypercholesterolemia/*drug therapy , Myocardium/*metabolism , Thiophenes/*pharmacology, Animals ; Calcium-Transporting ATPases/metabolism ; Disease Models, Animal ; Hypercholesterolemia/metabolism ; Hypercholesterolemia/pathology ; Male ; Myocardium/pathology ; Rats ; Rats, Wistar

المؤلفون: Pereira SL; Programa de Desenvolvimento de Fármacos, Instituto de Ciências Biomédicas, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, 21941-590, Brazil., Kummerle AE, Fraga CA, Barreiro EJ, Sudo RT, Zapata-Sudo G

المصدر: Fundamental & clinical pharmacology [Fundam Clin Pharmacol] 2014 Feb; Vol. 28 (1), pp. 29-41. Date of Electronic Publication: 2012 Sep 07.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Blackwell Science Country of Publication: England NLM ID: 8710411 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1472-8206 (Electronic) Linking ISSN: 07673981 NLM ISO Abbreviation: Fundam Clin Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Antihypertensive Agents/*pharmacology , Benzodioxoles/*pharmacology , Calcium Channels, L-Type/*metabolism , Hydrazones/*pharmacology , Vasodilator Agents/*pharmacology, Animals ; Aorta, Thoracic/drug effects ; Aorta, Thoracic/metabolism ; Calcium/metabolism ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/metabolism ; Male ; Muscle, Smooth, Vascular/drug effects ; Muscle, Smooth, Vascular/metabolism ; Papillary Muscles/drug effects ; Papillary Muscles/metabolism ; Potassium Chloride/metabolism ; Rats ; Rats, Inbred SHR ; Rats, Inbred WKY ; Vasodilation/drug effects

المؤلفون: Silva GA; Programa de Desenvolvimento de Fármacos, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil., Kummerle AE, Antunes F, Fraga CA, Barreiro EJ, Zapata-Sudo G, Sudo RT

المصدر: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas [Braz J Med Biol Res] 2013 Mar; Vol. 46 (3), pp. 263-9. Date of Electronic Publication: 2013 Mar 19.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Associação Brasileira de Divulgação Científica Country of Publication: Brazil NLM ID: 8112917 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1414-431X (Electronic) Linking ISSN: 0100879X NLM ISO Abbreviation: Braz J Med Biol Res Subsets: MEDLINE

مواضيع طبية MeSH: Hydrazines/*pharmacology , Hydrazones/*pharmacology , Hypnotics and Sedatives/*pharmacology , Motor Activity/*drug effects , Receptors, GABA/*drug effects , Thiophenes/*pharmacology, Animals ; Hydrazines/chemistry ; Hydrazones/chemistry ; Male ; Mice ; Receptors, GABA/physiology ; Thiophenes/chemistry

المؤلفون: Pereira SL; Instituto de Ciências Biomédicas, Programa de Desenvolvimento de Fármacos, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil. sharlene.pereira@yahoo.com.br, Kummerle AE, Fraga CA, Barreiro EJ, Rocha Nde N, Ferraz EB, do Nascimento JH, Sudo RT, Zapata-Sudo G

المصدر: European journal of pharmacology [Eur J Pharmacol] 2013 Feb 28; Vol. 702 (1-3), pp. 316-22. Date of Electronic Publication: 2013 Feb 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Benzodioxoles/*therapeutic use , Calcium Channel Blockers/*therapeutic use , Cardiomegaly/*drug therapy , Hydrazones/*therapeutic use , Hypertension, Pulmonary/*drug therapy, Acetylcholine/pharmacology ; Animals ; Benzodioxoles/pharmacology ; Calcium Channel Blockers/pharmacology ; Calcium Chloride/pharmacology ; Cardiomegaly/pathology ; Cardiomegaly/physiopathology ; Familial Primary Pulmonary Hypertension ; Hydrazones/pharmacology ; Hypertension, Pulmonary/chemically induced ; Hypertension, Pulmonary/pathology ; Hypertension, Pulmonary/physiopathology ; In Vitro Techniques ; Male ; Monocrotaline ; Phenylephrine/pharmacology ; Pulmonary Artery/drug effects ; Pulmonary Artery/pathology ; Pulmonary Artery/physiopathology ; Rats ; Rats, Wistar ; Vasoconstrictor Agents/pharmacology ; Vasodilator Agents/pharmacology

المؤلفون: Brito FC; Laboratório de Avaliação e Síntese de Substâncias Bioativas (LASSBio), Departamento de Fármacos, Universidade Federal do Rio de Janeiro (UFRJ), Centro de Ciências da Saúde (CCS), P.O. Box 68006, Ilha do Fundão, 21941-902, Rio de Janeiro, RJ, Brazil., Kummerle AE, Lugnier C, Fraga CA, Barreiro EJ, Miranda AL

المصدر: European journal of pharmacology [Eur J Pharmacol] 2010 Jul 25; Vol. 638 (1-3), pp. 5-12. Date of Electronic Publication: 2010 Apr 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Hydrazones/*pharmacology , Nucleotides, Cyclic/*metabolism , Platelet Aggregation/*drug effects , Platelet Aggregation Inhibitors/*pharmacology , Thiophenes/*pharmacology , Thromboxane A2/*antagonists & inhibitors, Animals ; Arachidonic Acid/antagonists & inhibitors ; Arachidonic Acid/pharmacology ; Bleeding Time ; Blood Platelets/drug effects ; Blood Platelets/metabolism ; Collagen/antagonists & inhibitors ; Collagen/pharmacology ; Female ; Humans ; Male ; Mice ; Molecular Structure ; Nucleotides, Cyclic/antagonists & inhibitors ; Nucleotides, Cyclic/pharmacology ; Phosphoric Diester Hydrolases/drug effects ; Rabbits ; Structure-Activity Relationship ; Thrombin/antagonists & inhibitors ; Thrombin/pharmacology ; Thromboxane A2/biosynthesis