المؤلفون: Kappelman MD; Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina. Electronic address: michael_kappelman@med.unc.edu., Wohl DA; Institute of Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Herfarth HH; Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, North Carolina., Firestine AM; Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Adler J; Susan B. Meister Child Health Evaluation and Research Center and Division of Pediatric Gastroenterology, University of Michigan, Ann Arbor, Michigan., Ammoury RF; Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Children's Hospital of The King's Daughters, Norfolk, Virginia., Aronow JE; Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Bass DM; Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Stanford University School of Medicine, Lucile Packard Children's Hospital, Palo Alto, California., Bass JA; Department of Pediatrics, School of Medicine, University of Missouri Kansas City, Division of Gastroenterology, Children's Mercy Kansas City, Kansas City, Missouri., Benkov K; Division of Pediatric Gastroenterology, Icahn School of Medicine at Mt Sinai, New York, New York., Tobi CB; University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina., Boccieri ME; Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Boyle BM; Division of Gastroenterology, Hepatology, and Nutrition, Nationwide Children's Hospital, Columbus, Ohio., Brinkman WB; Department of Pediatrics, University of Cincinnati College of Medicine, Division of General and Community Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Cabera JM; Division of Pediatric Gastroenterology, Department of Pediatrics, Children's Hospital of Wisconsin, Medical College of Wisconsin, Milwaukee, Wisconsin., Chun K; Esoterix Specialty Laboratory, Labcorp, Calabasas, California., Colletti RB; Division of Gastroenterology, Department of Pediatrics, University of Vermont, Burlington, Vermont., Dodds CM; James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Dorsey JM; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Nemours Children's Health, Jacksonville, Florida., Ebach DR; Division of Pediatric Gastroenterology, Hepatology, Pancreatology, and Nutrition, University of Iowa, Iowa City, Iowa., Entrena E; Progenika Biopharma, a Grifols Company, Derio, Bizkaia, Spain., Forrest CB; Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Philadelphia., Galanko JA; Center for Gastrointestinal Biology and Disease, Division of Gastroenterology and Hepatology, University of North Carolina School of Medicine, Chapel Hill, North Carolina., Grunow JE; University of Oklahoma Children's Physicians, Pediatric Gastroenterology, Oklahoma City, Oklahoma., Gulati AS; Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Ivanova A; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Jester TW; Department of Pediatrics, Division of Gastroenterology, University of Alabama at Birmingham, Birmingham, Alabama., Kaplan JL; Division of Pediatric Gastroenterology, Mass General for Children and Harvard Medical School, Boston, Massachusetts., Kugathasan S; Department of Pediatrics, Emory University, Atlanta, Georgia., Kusek ME; Division of Pediatric Gastroenterology, University of Nebraska Medical Center, Omaha, Nebraska., Leibowitz IH; Division of Gastroenterology, Hepatology and Nutrition, Children's National Medical Center, Department of Pediatrics, George Washington University, Washington, District of Columbia., Linville TM; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Levine Children's Hospital, Charlotte, North Carolina., Lipstein EA; Department of Pediatrics, University of Cincinnati College of Medicine, James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Margolis PA; Department of Pediatrics, University of Cincinnati College of Medicine, James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Minar P; Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio., Molle-Rios Z; Division of Pediatric Gastroenterology, Nemours Children's Hospital, Wilmington, Delaware., Moses J; Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, University Hospitals Rainbow Babies and Children's Hospital, Cleveland, Ohio., Olano KK; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Osaba L; Progenika Biopharma, a Grifols Company, Derio, Bizkaia, Spain., Palomo PJ; Division of Pediatric Gastroenterology, Nemours Children's Hospital, Orlando, Florida., Pappa H; Division of Pediatric Gastroenterology, Cardinal Glennon Children's Hospital, Saint Louis University School of Medicine, St Louis, Missouri., Park KT; Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Stanford University School of Medicine, Lucile Packard Children's Hospital, Palo Alto, California., Pashankar DS; Section of Pediatric Gastroenterology and Hepatology, Department of Pediatrics, Yale School of Medicine, Yale University, New Haven, Connecticut., Pitch L; ImproveCareNow Inc, Essex Junction, Vermont., Robinson M; Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Samson CM; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri., Sandberg KC; Department of Gastroenterology, Dayton Children's Hospital, Boonshoft School of Medicine, Wright State University, Dayton, Ohio., Schuchard JR; Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Philadelphia., Seid M; Department of Pediatrics, University of Cincinnati College of Medicine, Division of Pulmonary Medicine, James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Shelly KA; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana., Steiner SJ; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana., Strople JA; Division of Gastroenterology, Hepatology and Nutrition, Ann and Robert H. Lurie Children's Hospital of Chicago, Department of Pediatrics, Northwestern Feinberg School of Medicine, Chicago, Illinois., Sullivan JS; The University of Vermont Children's Hospital and Department of Pediatrics, Larner College of Medicine, The University of Vermont, Burlington, Vermont., Tung J; University of Oklahoma Children's Physicians, Pediatric Gastroenterology, Oklahoma City, Oklahoma., Wali P; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, State University of New York Upstate Medical University, Syracuse, New York., Zikry M; Esoterix Specialty Laboratory, Labcorp, Calabasas, California., Weinberger M; Department of Health Policy and Management, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Saeed SA; Boonshoft School of Medicine, Wright State University, Dayton Children's Hospital, Dayton, Ohio., Bousvaros A; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, Massachusetts.

المصدر: Gastroenterology [Gastroenterology] 2023 Jul; Vol. 165 (1), pp. 149-161.e7. Date of Electronic Publication: 2023 Mar 31.

نوع المنشور: Randomized Controlled Trial; Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 0374630 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0012 (Electronic) Linking ISSN: 00165085 NLM ISO Abbreviation: Gastroenterology Subsets: MEDLINE

مواضيع طبية MeSH: Methotrexate*/adverse effects , Tumor Necrosis Factor Inhibitors*, Child ; Humans ; Female ; Adolescent ; Male ; Adalimumab/adverse effects ; Antibodies, Monoclonal/adverse effects ; Infliximab/adverse effects ; Tumor Necrosis Factor-alpha ; Treatment Outcome

SCR Disease Name: Pediatric Crohn's disease

المؤلفون: Chu KK; Department of Dermatology, Harvard Medical School, Boston, MA, USA.; Wellman Center for Photomedicine, Boston, MA, USA., Kusek ME; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.; Mucosal Immunology and Biology Research Center, Boston, MA, USA., Liu L; Department of Dermatology, Harvard Medical School, Boston, MA, USA.; Wellman Center for Photomedicine, Boston, MA, USA., Som A; Wellman Center for Photomedicine, Boston, MA, USA.; Mucosal Immunology and Biology Research Center, Boston, MA, USA., Yonker LM; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.; Mucosal Immunology and Biology Research Center, Boston, MA, USA., Leung H; Department of Dermatology, Harvard Medical School, Boston, MA, USA.; Wellman Center for Photomedicine, Boston, MA, USA., Cui D; Department of Dermatology, Harvard Medical School, Boston, MA, USA.; Wellman Center for Photomedicine, Boston, MA, USA., Ryu J; Wellman Center for Photomedicine, Boston, MA, USA., Eaton AD; Mucosal Immunology and Biology Research Center, Boston, MA, USA., Tearney GJ; Department of Dermatology, Harvard Medical School, Boston, MA, USA.; Wellman Center for Photomedicine, Boston, MA, USA.; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA., Hurley BP; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.; Mucosal Immunology and Biology Research Center, Boston, MA, USA.

المصدر: Scientific reports [Sci Rep] 2017 Apr 03; Vol. 8, pp. 45789. Date of Electronic Publication: 2017 Apr 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Transendothelial and Transepithelial Migration*, Colorectal Neoplasms/*pathology , Epithelium/*physiology , Neutrophils/*physiology , Peroxidase/*metabolism , Tomography, Optical Coherence/*methods, Cell Adhesion ; Cells, Cultured ; Chemotaxis, Leukocyte/physiology ; Coculture Techniques ; Humans ; Neutrophils/cytology

المؤلفون: Kusek ME; Department of Pediatrics, Harvard Medical School., Pazos MA, Pirzai W, Hurley BP

المصدر: Journal of visualized experiments : JoVE [J Vis Exp] 2014 Jan 06 (83), pp. e50823. Date of Electronic Publication: 2014 Jan 06.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Video-Audio Media

بيانات الدورية: Publisher: MYJoVE Corporation Country of Publication: United States NLM ID: 101313252 Publication Model: Electronic Cited Medium: Internet ISSN: 1940-087X (Electronic) Linking ISSN: 1940087X NLM ISO Abbreviation: J Vis Exp Subsets: MEDLINE

مواضيع طبية MeSH: Coculture Techniques/*methods , Neutrophils/*immunology , Pseudomonas Infections/*immunology , Pseudomonas aeruginosa/*immunology , Transendothelial and Transepithelial Migration/*immunology, Cell Line ; Epithelial Cells/immunology ; Epithelial Cells/microbiology ; Epithelial Cells/pathology ; Humans ; Lung/cytology ; Lung/immunology ; Lung/microbiology ; Neutrophils/microbiology ; Neutrophils/pathology ; Pseudomonas Infections/pathology