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1
المؤلفون: Saroja Ramanujan, Kristin R. Wildsmith, Y. Lu, Y. Zhang, Raymond K. Tong, Jitendra Kanodia, Dennis, Daniela Bumbaca, Sean B. Joseph, Jessica Couch, Ryan J. Watts, Kapil Gadkar, Ernst James, Jasvinder K. Atwal, Kimberly Scearce-Levie, Kwame Hoyte, W. Luk
المصدر: CPT: Pharmacometrics & Systems Pharmacology
مصطلحات موضوعية: 0301 basic medicine, Bispecific antibody, Transferrin receptor, Computational biology, 030226 pharmacology & pharmacy, 03 medical and health sciences, Drug Delivery Systems, 0302 clinical medicine, Antibodies, Bispecific, Receptors, Transferrin, medicine, Animals, Humans, Pharmacology (medical), Prospective Studies, Receptor, Brain uptake, biology, Brain, Original Articles, Human brain, Macaca fascicularis, 030104 developmental biology, medicine.anatomical_structure, Blood-Brain Barrier, Drug Design, Modeling and Simulation, Immunology, biology.protein, Original Article, Antibody
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2
المؤلفون: Y. Joy Yu Zuchero, William H Montgomery, Laura DeForge, William J. Meilandt, Kwame Hoyte, Wilman Luk, Dongping He, Ryan J. Watts, Jasvinder K. Atwal, Kimberly Scearce-Levie, Yanmei Lu
المصدر: Bioanalysis. 8:1067-1075
مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, Clinical Biochemistry, Enzyme-Linked Immunosorbent Assay, Mice, Transgenic, Endogeny, Transferrin receptor, Disease, Analytical Chemistry, Mice, 03 medical and health sciences, 0302 clinical medicine, Alzheimer Disease, Antibodies, Bispecific, Drug Discovery, Receptors, Transferrin, Amyloid precursor protein, Animals, Aspartic Acid Endopeptidases, Humans, Medicine, General Pharmacology, Toxicology and Pharmaceutics, Amyloid beta-Peptides, biology, business.industry, Brain, General Medicine, Peptide Fragments, Disease Models, Animal, Medical Laboratory Technology, 030104 developmental biology, Drug development, Immunology, biology.protein, Cancer research, Biomarker (medicine), Amyloid Precursor Protein Secretases, Antibody, business, Biomarkers, 030217 neurology & neurosurgery
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3
المؤلفون: Mark S. Dennis, James A. Ernst, Christine Tan, Dara Y. Kallop, Raymond K. Tong, Xiaocheng Chen, Ben Chih, Melanie A. Huntley, Yanmei Lu, Shuo Zhang, Robby M. Weimer, Kwame Hoyte, Xiaoying Gao, Daniela Bumbaca, Y. Joy Yu Zuchero, Wilman Luk, Ryan J. Watts, Donald S. Kirkpatrick, Nga Bien-Ly, Lilian Phu
المصدر: Neuron. 89:70-82
مصطلحات موضوعية: Proteomics, 0301 basic medicine, Fusion Regulatory Protein 1, Heavy Chain, Microarray, Neuroscience(all), Blood–brain barrier, Antibodies, Transcriptome, Mice, 03 medical and health sciences, Receptors, Transferrin, medicine, Animals, biology, Proteomic Profiling, General Neuroscience, Brain, Endothelial Cells, Biological Transport, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Transcytosis, Blood-Brain Barrier, Basigin, Immunology, biology.protein, GLUT1, Antibody
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4
المؤلفون: Aarno Palotie, Daniel F. Gudbjartsson, Stacy Steinberg, Thorlakur Jonsson, Augustine Kong, Kari Stefansson, Jon Snaedal, Ryan J. Watts, Timothy W. Behrens, Patrick Sulem, Palmi V. Jonsson, Kwame Hoyte, Unnur Thorsteinsdottir, Yichin Liu, Gyda Bjornsdottir, Sigurbjorn Bjornsson, Ole A. Andreassen, Olafur T. Magnusson, Johanna Huttenlocher, Robert R. Graham, Erik G. Jönsson, Amy Gustafson, Janice A. Maloney, Yanmei Lu, Jasvinder K. Atwal, Hreinn Stefansson, Tushar Bhangale
المصدر: Nature. 488:96-99
مصطلحات موضوعية: Aging, Age-related cognitive decline, Plaque, Amyloid, Disease, Amyloid beta-Protein Precursor, 03 medical and health sciences, Cognition, 0302 clinical medicine, Alzheimer Disease, Amyloid precursor protein, Aspartic Acid Endopeptidases, Humans, Medicine, Dementia, Genetic Predisposition to Disease, Cognitive decline, Allele, Gene, Alleles, 030304 developmental biology, 0303 health sciences, Multidisciplinary, biology, business.industry, medicine.disease, HEK293 Cells, Mutation, Immunology, biology.protein, Verubecestat, Amyloid Precursor Protein Secretases, Cognition Disorders, business, 030217 neurology & neurosurgery
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5
المؤلفون: Saileta Prabhu, Jeff Lutman, Yanmei Lu, Rong Deng, Y. Gloria Meng, Laura DeForge, Frank-Peter Theil, Suhasini Iyer, Paul J. Fielder, Kwame Hoyte
المصدر: mAbs. 4:101-109
مصطلحات موضوعية: medicine.drug_class, Injections, Subcutaneous, Immunology, Antibody Affinity, Biological Availability, Mice, SCID, Receptors, Fc, Pharmacology, Monoclonal antibody, Immunoglobulin G, Mice, Neonatal Fc receptor, Report, medicine, Animals, Humans, Immunology and Allergy, biology, Catabolism, Chemistry, Histocompatibility Antigens Class I, Potential effect, Antibodies, Monoclonal, Bioavailability, biology.protein, Antibody, Function (biology), Protein Binding
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6
المؤلفون: C. Andrew Boswell, Jason DeVoss, Oded Foreman, Wilman Luk, Kwame Hoyte, Yanmei Lu, Nga Bien-Ly, Sheila Ulufatu, Marcel P. van der Brug, Ryan J. Watts, Vera Shihadeh, Thomas G. Beach, Surinder Jeet
المصدر: Neuron. 88(2)
مصطلحات موضوعية: Male, Transgene, Neuroscience(all), Recombinant Fusion Proteins, Mice, Transgenic, Disease, Blood–brain barrier, Antibodies, Mice, Alzheimer Disease, medicine, Animals, Humans, Receptor, Mice, Knockout, biology, General Neuroscience, Multiple sclerosis, medicine.disease, Mice, Inbred C57BL, Disease Models, Animal, medicine.anatomical_structure, Blood-Brain Barrier, Immunology, biology.protein, cardiovascular system, Female, Alzheimer's disease, Antibody, Psychology, Single-Chain Antibodies
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7
المؤلفون: Yanmei Lu, Raymond K. Tong, Janice A. Maloney, Kimberly Scearce-Levie, Jessica Couch, William J. Meilandt, Kwame Hoyte, Mark S. Dennis, James A. Ernst, Wilman Luk, Yin Zhang, Jasvinder K. Atwal, Ryan J. Watts, Kapil Gadkar, Kristin R. Wildsmith, Maria Hersom, Nga Bien-Ly, Christine Tan, Daniela Bumbaca, Y. Joy Yu
المصدر: Science translational medicine. 6(261)
مصطلحات موضوعية: Transgene, Down-Regulation, Vascular permeability, Transferrin receptor, Mice, Transgenic, CHO Cells, Biology, Pharmacology, Cross Reactions, Blood–brain barrier, Transfection, Capillary Permeability, Cricetulus, Antigen, Antibody Specificity, Antigens, CD, mental disorders, Antibodies, Bispecific, Receptors, Transferrin, medicine, Animals, Aspartic Acid Endopeptidases, Humans, Receptor, Mice, Inbred BALB C, Amyloid beta-Peptides, Biological Transport, General Medicine, Peptide Fragments, Mice, Inbred C57BL, Macaca fascicularis, medicine.anatomical_structure, HEK293 Cells, Blood-Brain Barrier, Immunology, biology.protein, Administration, Intravenous, Antibody, Amyloid Precursor Protein Secretases
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce7b27a7d0c16c2361ffcf271d85ead
https://pubmed.ncbi.nlm.nih.gov/25503335 -
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المؤلفون: Paul T. Martin, Kwame Hoyte, Vianney Jayasinha, Bing Xia
المصدر: The American Journal of Pathology. 164:711-718
مصطلحات موضوعية: Male, musculoskeletal diseases, congenital, hereditary, and neonatal diseases and abnormalities, mdx mouse, medicine.medical_specialty, Utrophin, animal diseases, Duchenne muscular dystrophy, Blotting, Western, Biology, Pathology and Forensic Medicine, Dystroglycans, Mice, Sarcolemma, Internal medicine, medicine, Dystroglycan, Animals, Humans, Myocyte, Muscular dystrophy, Muscle, Skeletal, Creatine Kinase, Membrane Glycoproteins, Membrane Proteins, Skeletal muscle, musculoskeletal system, medicine.disease, Up-Regulation, Muscular Dystrophy, Duchenne, Cytoskeletal Proteins, Disease Models, Animal, medicine.anatomical_structure, Endocrinology, Mice, Inbred mdx, biology.protein, tissues, Regular Articles
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9
المؤلفون: Paul T. Martin, T. J. Deerinck, Bing Xia, Anja Kammesheidt, Kwame Hoyte, Mark H. Ellisman
المصدر: Developmental Biology. 242:58-73
مصطلحات موضوعية: Synaptic cleft, Molecular Sequence Data, Muscle Fibers, Skeletal, Neuromuscular Junction, Mice, Transgenic, dystroglycan, Neuromuscular junction, Synapse, Mice, synapse, Laminin, satellite cell, Utrophin, medicine, Animals, Myocyte, Amino Acid Sequence, Muscle, Skeletal, Molecular Biology, biology, Skeletal muscle, Cell Biology, GalNAc, Cell biology, Microscopy, Electron, medicine.anatomical_structure, Biochemistry, biology.protein, N-Acetylgalactosaminyltransferases, Neural cell adhesion molecule, Developmental Biology
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10
المؤلفون: Ryan J. Watts, Kwame Hoyte, Jasvinder K. Atwal, Yanmei Lu, Wilman Luk, Kapil Gadkar, Kimberly Scearce-Levie, William J. Meilandt
المصدر: Alzheimer's & Dementia. 9
مصطلحات موضوعية: medicine.diagnostic_test, Amyloid, Epidemiology, Chemistry, Health Policy, Amyloidosis, Fibril, medicine.disease, Blot, Psychiatry and Mental health, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Developmental Neuroscience, Western blot, Covalent bond, medicine, Biophysics, Curcumin, Neurology (clinical), Geriatrics and Gerontology, Binding site