المؤلفون: Dianwen Ju, Yang Hu, Wei Chen

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 8, Pp 1347-1359 (2020)

مصطلحات موضوعية: CHOP, CCAAT/enhancer binding homologous protein, Genetic enhancement, AAVs, adeno-associated viruses, BCSFB, blood–cerebrospinal fluid barrier, SMN, survival motor neuron, Review, Disease, Bioinformatics, CSF, cerebrospinal fluid, PD, Parkinson's disease, IDS, iduronate 2-sulfatase, ASOs, antisense oligonucleotides, Bip, glucose regulated protein 78, UPR, unfolded protein response, 0302 clinical medicine, Medicine, HD, Huntington's disease, TFEB, transcription factor EB, General Pharmacology, Toxicology and Pharmaceutics, BBB, blood–brain barrier, Therapeutic strategy, GAD, glutamic acid decarboxylase, TPP1, tripeptidyl peptidase 1, 0303 health sciences, RNAi, RNA interference, SUMF, sulfatase-modifying factor, RPE, retinal pigmented epithelial, 030220 oncology & carcinogenesis, AADC, aromatic-l-amino-acid, AD, Alzheimer's disease, LVs, retrovirus/lentivirus, AD - Alzheimer's disease, GDNF, glial derived neurotrophic factor, NGF, nerve growth factor, GAA, lysosomal acid α-glucosidase, HTT, mutant huntingtin, mTOR, mammalian target of rapamycin, ARSA, arylsulfatase A, CNS, central nervous system, ER, endoplasmic reticulum, 03 medical and health sciences, Gene therapy, SOD, superoxide dismutase, TREM2, triggering receptor expressed on myeloid cells 2, ASPA, aspartoacylase, Adeno-associated viruses, 030304 developmental biology, Lamp2a, lysosomal-associated membrane protein 2a, PGRN, Progranulin, Adv, adenovirus, BRB, blood–retina barrier, PD - Parkinson's disease, CLN6, ceroidlipofuscinosis neuronal protein 6, business.industry, lcsh:RM1-950, Delivery routes, PINK1, putative kinase 1, PTEN, phosphatase and tensin homolog, RGCs, retinal ganglion cells, Clinical trial, FDA, U.S. Food and Drug Administration, SGSH, lysosomal heparan-N-sulfamidase gene, lcsh:Therapeutics. Pharmacology, Central nervous system, HSPGs, heparin sulfate proteoglycans, siRNA, small interfering RNA, Neurodegenerative disorders, business, ZFPs, zinc finger proteins, CSF - Cerebrospinal fluid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b140cd71516f9b1622ac1023338efec
https://doi.org/10.1016/j.apsb.2020.01.015

المؤلفون: Jean Paul Briand, Nicolas Page, Sylviane Muller, Christophe Macri, Nicolas Schall, Ana Maria Cuervo, Inmaculada Tasset, Fengjuan Wang

المساهمون: Biotechnologie et signalisation cellulaire (BSC), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Institut de recherche de l'Ecole de biotechnologie de Strasbourg (IREBS), Immunopathologie et chimie thérapeutique (ICT), Institut de biologie moléculaire et cellulaire (IBMC), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Autophagy
Autophagy, Taylor & Francis, 2015, 11 (3), pp.472-486. ⟨10.1080/15548627.2015.1017179⟩

مصطلحات موضوعية: Phosphopeptides, Mice, Inbred MRL lpr, LC-MS, liquid chromatography-mass spectrometry, NBD, nucleotide binding domain, [SDV.BIO]Life Sciences [q-bio]/Biotechnology, T-Lymphocytes, Autoimmunity, CPZ: chlorpromazine, SLE, systemic lupus erythematosus, chemistry.chemical_compound, Mice, Chaperone-mediated autophagy, paraquat, 1, 1′-dimethyl-4, 4′-bipyridyldinium dichloride, qRT-PCR, quantitative reverse transcriptase-polymerase chain reaction, immune system diseases, Serine, Lupus Erythematosus, Systemic, antigen-presenting cells, ALF, artificial lysosomal fluid, RPL5, ribosomal protein L5, Phosphorylation, skin and connective tissue diseases, chaperone-mediated autophagy, HSPA8/HSC70, education.field_of_study, B-Lymphocytes, SBD, substrate binding domain, Sciences du Vivant [q-bio]/Biotechnologies, ELISA, enzyme-linked immunosorbent assay, MHCII, major histocompatibility complex class II, class II MHC molecules, Endocytosis, Basic Research Paper, CMA, chaperone-mediated autophagy, Cell biology, Lysosomal lumen, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, bodipy: BODIPY FL C5 Lactosylceramide/bovine serum albumin, LAMP2A, lysosomal-associated membrane protein 2A, RP-HPLC, reversed-phase high-performance liquid chromatography, autophagy, CTSD, cathepsin D, PBS, phosphate-buffered saline, Endosomes, Biology, SEM, standard error of the mean, Ribosomal protein L5, Ribonucleoprotein, U1 Small Nuclear, lysosomal chaperones, TFA, trifluoroacetic acid, Sequestosome 1, lysosomes, CoIP, coimmunoprecipitation, Downregulation and upregulation, Animals, Humans, education, Antigen-presenting cell, Molecular Biology, SQSTM1/p62, sequestosome 1, iv, intravenous, SNRNP70/U170K: small nuclear ribonucleoprotein 70kDa, Autophagy, HSC70 Heat-Shock Proteins, Histocompatibility Antigens Class II, Cell Biology, lupus, HCQ, hydroxychloroquine, LC3-II, MAP1LC3-II, Molecular biology, Peptide Fragments, TF, transferrin, chemistry, APC, antigen-presenting cell, Phosphoserine, heat shock proteins, NIH 3T3 Cells, FCS, fetal calf serum, SD, standard deviation, DAPI, 4′, 6-diamidino-2-phenylindole, Molecular Chaperones, B lymphocytes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd3852162ef8e4c9b772246960eadd1b
https://hal.archives-ouvertes.fr/hal-02988901

المؤلفون: Chen W; Department of Biological Medicines, Fudan University School of Pharmacy, Shanghai 201203, China.; Department of Ophthalmology, Stanford University School of Medicine, Palo Alto, CA 94304, USA., Hu Y; Department of Ophthalmology, Stanford University School of Medicine, Palo Alto, CA 94304, USA., Ju D; Department of Biological Medicines, Fudan University School of Pharmacy, Shanghai 201203, China.

المصدر: Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2020 Aug; Vol. 10 (8), pp. 1347-1359. Date of Electronic Publication: 2020 Jan 31.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101600560 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2211-3835 (Print) Linking ISSN: 22113835 NLM ISO Abbreviation: Acta Pharm Sin B Subsets: PubMed not MEDLINE

المؤلفون: Macri C; a CNRS; Immunopathologie et chimie thérapeutique/Laboratory of excellence Medalis ; Institut de Biologie Moléculaire et Cellulaire ; Strasbourg , France., Wang F, Tasset I, Schall N, Page N, Briand JP, Cuervo AM, Muller S

المصدر: Autophagy [Autophagy] 2015; Vol. 11 (3), pp. 472-86.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265188 Publication Model: Print Cited Medium: Internet ISSN: 1554-8635 (Electronic) Linking ISSN: 15548627 NLM ISO Abbreviation: Autophagy Subsets: MEDLINE

مواضيع طبية MeSH: Autophagy*, Molecular Chaperones/*chemistry , Peptide Fragments/*chemistry , Phosphopeptides/*chemistry , Ribonucleoprotein, U1 Small Nuclear/*chemistry, Animals ; Autoimmunity ; B-Lymphocytes/immunology ; Endocytosis ; Endosomes/metabolism ; HSC70 Heat-Shock Proteins/chemistry ; Histocompatibility Antigens Class II/metabolism ; Humans ; Lupus Erythematosus, Systemic/immunology ; Lysosomes/chemistry ; Lysosomes/metabolism ; Mice ; Mice, Inbred MRL lpr ; NIH 3T3 Cells ; Phosphorylation ; Serine/chemistry ; T-Lymphocytes/immunology