المؤلفون: Sharma PK; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093-0652, U.S.A., Weng JH; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093-0652, U.S.A., Manschwetus JT; Department of Biochemistry, University of Kassel, Heinrich-Plett-Str. 40, 34132 Kassel, Hessen, Germany., Wu J; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093-0652, U.S.A., Ma W; Department of Physics, University of Vermont, Burlington, Vermont., Herberg FW; Department of Biochemistry, University of Kassel, Heinrich-Plett-Str. 40, 34132 Kassel, Hessen, Germany., Taylor SS; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093-0652, U.S.A.; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093-0652, U.S.A.

المصدر: The Biochemical journal [Biochem J] 2024 Feb 21; Vol. 481 (4), pp. 313-327.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE

مواضيع طبية MeSH: Protein Serine-Threonine Kinases*/metabolism , Leucine-Rich Repeat Proteins*, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/metabolism ; Protein Domains ; Mutation ; Peptides/metabolism ; Phosphorylation

المؤلفون: Nieradko-Iwanicka B; Hygiene and Epidemiology Department, Medical University of Lublin, Poland Medical University of Lublin, Hygiene and Epidemiology Department, Chodzki 7 Street, Lublin 20-093, Poland. Electronic address: barbara.nieradko-iwanicka@umlub.pl., Piasecki J; Doctoral School, Medical University of Lublin, Chodzki 7 Street, Lublin 20-093, Poland., Borzęcki A; Hygiene and Epidemiology Department, Medical University of Lublin, Poland Medical University of Lublin, Hygiene and Epidemiology Department, Chodzki 7 Street, Lublin 20-093, Poland.

المصدر: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 May; Vol. 174, pp. 116480. Date of Electronic Publication: 2024 Mar 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

مواضيع طبية MeSH: Leucine*/*analogs & derivatives, Lipopolysaccharides* , Spleen*/drug effects , Spleen*/metabolism , Rats, Wistar* , Matrix Metalloproteinase 2*/metabolism , Lung*/drug effects , Lung*/enzymology , Lung*/pathology , Lung*/metabolism , Sepsis*/drug therapy , Sepsis*/chemically induced , Matrix Metalloproteinase 12*/metabolism , Disease Models, Animal* , Leucine*/pharmacology , Leucine*/therapeutic use, Animals ; Male ; Rats ; Matrix Metalloproteinase Inhibitors/pharmacology

المؤلفون: Usenko TS; Molecular and Radiation Biophysics Division, Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute»,188300 Gatchina, Russia.; Department of Molecular Genetic and Nanobiological Technologies Research Center, Pavlov First Saint-Petersburg State Medical University, 197022 Saint Petersburg, Russia., Timofeeva A; Neurology Department, Pavlov First Saint-Petersburg State Medical University, 197022 Saint Petersburg, Russia., Beletskaia M; Neurology Department, Pavlov First Saint-Petersburg State Medical University, 197022 Saint Petersburg, Russia., Basharova K; Molecular and Radiation Biophysics Division, Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute»,188300 Gatchina, Russia., Baydakova G; Molecular and Radiation Biophysics Division, Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute»,188300 Gatchina, Russia.; Hereditary Metabolic Diseases Laboratory, Research Centre for Medical Genetics, 115522 Moscow, Russia., Bezrukova A; Molecular and Radiation Biophysics Division, Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute»,188300 Gatchina, Russia.; Department of Molecular Genetic and Nanobiological Technologies Research Center, Pavlov First Saint-Petersburg State Medical University, 197022 Saint Petersburg, Russia., Grunina M; Molecular and Radiation Biophysics Division, Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute»,188300 Gatchina, Russia., Emelyanov A; Molecular and Radiation Biophysics Division, Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute»,188300 Gatchina, Russia.; Department of Molecular Genetic and Nanobiological Technologies Research Center, Pavlov First Saint-Petersburg State Medical University, 197022 Saint Petersburg, Russia., Miliukhina I; Molecular and Radiation Biophysics Division, Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute»,188300 Gatchina, Russia.; Department of Molecular Genetic and Nanobiological Technologies Research Center, Pavlov First Saint-Petersburg State Medical University, 197022 Saint Petersburg, Russia.; Scientific and Clinical Center for Neurodegenerative Diseases and Botulinum Therapy, Institute of the Human Brain RAS, 197376 Saint Petersburg, Russia., Zakharova E; Hereditary Metabolic Diseases Laboratory, Research Centre for Medical Genetics, 115522 Moscow, Russia., Pchelina S; Molecular and Radiation Biophysics Division, Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute»,188300 Gatchina, Russia.; Department of Molecular Genetic and Nanobiological Technologies Research Center, Pavlov First Saint-Petersburg State Medical University, 197022 Saint Petersburg, Russia.

المصدر: Journal of integrative neuroscience [J Integr Neurosci] 2024 Jan 16; Vol. 23 (1), pp. 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: IMR Press Country of Publication: Singapore NLM ID: 101156357 Publication Model: Print Cited Medium: Internet ISSN: 0219-6352 (Print) Linking ISSN: 02196352 NLM ISO Abbreviation: J Integr Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Glucosylceramidase*/genetics , Glucosylceramidase*/metabolism , Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/genetics , Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/metabolism , Parkinson Disease*/genetics, Humans ; Middle Aged ; Disease Progression ; Hydrolases/genetics ; Leucine/genetics ; Lysosomes/metabolism ; Mutation ; Sphingolipids

المؤلفون: Otsuka Y; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan., Hara A; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan., Minaga K; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan., Sekai I; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan., Kurimoto M; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan., Masuta Y; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan., Takada R; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan., Yoshikawa T; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan., Kamata K; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan., Kudo M; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan., Watanabe T; Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan.

المصدر: Clinical and experimental immunology [Clin Exp Immunol] 2023 Dec 12; Vol. 214 (2), pp. 182-196.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0057202 Publication Model: Print Cited Medium: Internet ISSN: 1365-2249 (Electronic) Linking ISSN: 00099104 NLM ISO Abbreviation: Clin Exp Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Pancreatitis*/metabolism , Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/genetics , Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/metabolism, Animals ; Mice ; Acute Disease ; Cytokines/metabolism ; Leucine ; Mice, Transgenic ; NF-kappa B/metabolism

المؤلفون: van Zwol W; Department of Pediatrics , University Medical Center Groningen, University of Groningen , Groningen , the Netherlands., Rimbert A; Université de Nantes, CNRS, INSERM, l'institut du thorax , Nantes , France., Wolters JC; Department of Pediatrics , University Medical Center Groningen, University of Groningen , Groningen , the Netherlands., Smit M; Department of Pediatrics , University Medical Center Groningen, University of Groningen , Groningen , the Netherlands., Bloks VW; Department of Pediatrics , University Medical Center Groningen, University of Groningen , Groningen , the Netherlands., Kloosterhuis NJ; Department of Pediatrics , University Medical Center Groningen, University of Groningen , Groningen , the Netherlands., Huijkman NCA; Department of Pediatrics , University Medical Center Groningen, University of Groningen , Groningen , the Netherlands., Koster MH; Department of Pediatrics , University Medical Center Groningen, University of Groningen , Groningen , the Netherlands., Tharehalli U; Department of Pediatrics , University Medical Center Groningen, University of Groningen , Groningen , the Netherlands., de Neck SM; Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine , Utrecht University , Utrecht , the Netherlands., Bournez C; Division of Drug Discovery and Safety , Leiden Academic Center for Drug Research, Leiden University , Leiden , The Netherlands., Fuh MM; Department of Biochemistry and Molecular Cell Biology , University Medical Center Hamburg-Eppendorf , Hamburg , Germany., Kuipers J; Department of Biomedical Sciences of Cells and Systems , University of Groningen, University Medical Center Groningen , Groningen , the Netherlands., Rajan S; Department of Foundations of Medicine , NYU Long Island School of Medicine , Mineola , New York , USA., de Bruin A; Department of Pediatrics , University Medical Center Groningen, University of Groningen , Groningen , the Netherlands.; Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine , Utrecht University , Utrecht , the Netherlands., Ginsberg HN; Department of Medicine , Columbia University, Vagelos College of Physicians and Surgeons , New York , New York , USA., van Westen GJP; Division of Drug Discovery and Safety , Leiden Academic Center for Drug Research, Leiden University , Leiden , The Netherlands., Hussain MM; Department of Foundations of Medicine , NYU Long Island School of Medicine , Mineola , New York , USA., Scheja L; Department of Biochemistry and Molecular Cell Biology , University Medical Center Hamburg-Eppendorf , Hamburg , Germany., Heeren J; Department of Biochemistry and Molecular Cell Biology , University Medical Center Hamburg-Eppendorf , Hamburg , Germany., Zimmerman P; NEBION AG , Zurich , Switzerland., van de Sluis B; Department of Pediatrics , University Medical Center Groningen, University of Groningen , Groningen , the Netherlands., Kuivenhoven JA; Department of Pediatrics , University Medical Center Groningen, University of Groningen , Groningen , the Netherlands.

المصدر: Hepatology (Baltimore, Md.) [Hepatology] 2023 Nov 01; Vol. 78 (5), pp. 1418-1432. Date of Electronic Publication: 2022 Oct 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 8302946 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3350 (Electronic) Linking ISSN: 02709139 NLM ISO Abbreviation: Hepatology Subsets: MEDLINE

مواضيع طبية MeSH: Atherosclerosis*/blood , Atherosclerosis*/genetics , Atherosclerosis*/metabolism , Atherosclerosis*/prevention & control , Lipoproteins, VLDL*/biosynthesis , Lipoproteins, VLDL*/blood , Lipoproteins, VLDL*/metabolism , Non-alcoholic Fatty Liver Disease*/blood , Non-alcoholic Fatty Liver Disease*/genetics , Non-alcoholic Fatty Liver Disease*/metabolism , Small Leucine-Rich Proteoglycans*/genetics , Small Leucine-Rich Proteoglycans*/metabolism, Animals ; Female ; Humans ; Male ; Mice ; Apolipoproteins B/blood ; Leucine ; Liver/metabolism ; Triglycerides/blood

المؤلفون: Zhu C; Department of Comparative Biomedical Sciences, Royal Veterinary College, University of London, London NW1 0TU, UK.; Department of Neurodegenerative diseases, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK., Herbst S; Department of Comparative Biomedical Sciences, Royal Veterinary College, University of London, London NW1 0TU, UK.; Department of Neurodegenerative diseases, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA., Lewis PA; Department of Comparative Biomedical Sciences, Royal Veterinary College, University of London, London NW1 0TU, UK.; Department of Neurodegenerative diseases, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.

المصدر: Journal of cell science [J Cell Sci] 2023 Sep 01; Vol. 136 (17). Date of Electronic Publication: 2023 Sep 12.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Company of Biologists Country of Publication: England NLM ID: 0052457 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9137 (Electronic) Linking ISSN: 00219533 NLM ISO Abbreviation: J Cell Sci Subsets: MEDLINE

مواضيع طبية MeSH: Parkinson Disease*/genetics , Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/genetics, Humans ; Leucine ; Mutation

المؤلفون: Jiang H; Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; The Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; Key Laboratory of Soybean Disease and Pest Control (Ministry of Agriculture and Rural Affairs), Nanjing Agricultural University, 210095, Nanjing, China., Xia Y; Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; The Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; Key Laboratory of Soybean Disease and Pest Control (Ministry of Agriculture and Rural Affairs), Nanjing Agricultural University, 210095, Nanjing, China., Zhang S; Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; The Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; Key Laboratory of Soybean Disease and Pest Control (Ministry of Agriculture and Rural Affairs), Nanjing Agricultural University, 210095, Nanjing, China., Zhang Z; Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; The Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; Key Laboratory of Soybean Disease and Pest Control (Ministry of Agriculture and Rural Affairs), Nanjing Agricultural University, 210095, Nanjing, China., Feng H; Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; The Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; Key Laboratory of Soybean Disease and Pest Control (Ministry of Agriculture and Rural Affairs), Nanjing Agricultural University, 210095, Nanjing, China., Zhang Q; Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; The Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; Key Laboratory of Soybean Disease and Pest Control (Ministry of Agriculture and Rural Affairs), Nanjing Agricultural University, 210095, Nanjing, China., Chen X; Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; The Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; Key Laboratory of Soybean Disease and Pest Control (Ministry of Agriculture and Rural Affairs), Nanjing Agricultural University, 210095, Nanjing, China., Xiao J; Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; The Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; Key Laboratory of Soybean Disease and Pest Control (Ministry of Agriculture and Rural Affairs), Nanjing Agricultural University, 210095, Nanjing, China., Yang S; Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; The Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; Key Laboratory of Soybean Disease and Pest Control (Ministry of Agriculture and Rural Affairs), Nanjing Agricultural University, 210095, Nanjing, China., Zeng M; Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; The Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; Key Laboratory of Soybean Disease and Pest Control (Ministry of Agriculture and Rural Affairs), Nanjing Agricultural University, 210095, Nanjing, China., Chen Z; Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; The Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; Key Laboratory of Soybean Disease and Pest Control (Ministry of Agriculture and Rural Affairs), Nanjing Agricultural University, 210095, Nanjing, China., Ouyang H; Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; The Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; Key Laboratory of Soybean Disease and Pest Control (Ministry of Agriculture and Rural Affairs), Nanjing Agricultural University, 210095, Nanjing, China., He X; Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; The Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; Key Laboratory of Soybean Disease and Pest Control (Ministry of Agriculture and Rural Affairs), Nanjing Agricultural University, 210095, Nanjing, China., Sun G; Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; The Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; Key Laboratory of Soybean Disease and Pest Control (Ministry of Agriculture and Rural Affairs), Nanjing Agricultural University, 210095, Nanjing, China., Wu J; Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; The Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; Key Laboratory of Soybean Disease and Pest Control (Ministry of Agriculture and Rural Affairs), Nanjing Agricultural University, 210095, Nanjing, China., Dong S; Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; The Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; Key Laboratory of Soybean Disease and Pest Control (Ministry of Agriculture and Rural Affairs), Nanjing Agricultural University, 210095, Nanjing, China., Ye W; Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; The Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; Key Laboratory of Soybean Disease and Pest Control (Ministry of Agriculture and Rural Affairs), Nanjing Agricultural University, 210095, Nanjing, China., Ma Z; Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; The Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; Key Laboratory of Soybean Disease and Pest Control (Ministry of Agriculture and Rural Affairs), Nanjing Agricultural University, 210095, Nanjing, China., Wang Y; Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; The Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; Key Laboratory of Soybean Disease and Pest Control (Ministry of Agriculture and Rural Affairs), Nanjing Agricultural University, 210095, Nanjing, China., Wang Y; Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; The Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu, 210095, China.; Key Laboratory of Soybean Disease and Pest Control (Ministry of Agriculture and Rural Affairs), Nanjing Agricultural University, 210095, Nanjing, China.

المصدر: The New phytologist [New Phytol] 2023 Oct; Vol. 240 (2), pp. 784-801. Date of Electronic Publication: 2023 Aug 24.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley on behalf of New Phytologist Trust Country of Publication: England NLM ID: 9882884 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-8137 (Electronic) Linking ISSN: 0028646X NLM ISO Abbreviation: New Phytol Subsets: MEDLINE

مواضيع طبية MeSH: Leucine-Rich Repeat Proteins* , Phytophthora*, Animals ; Nicotiana/genetics ; Leucine ; Immunity, Innate ; Mammals

المؤلفون: Albus A; Therapy Research in Neurogeriatrics, Center for Translational Neuro- and Behavioral Sciences, University of Duisburg-Essen, University Hospital Essen, 45147 Essen, Germany.; Department for Neurology, Philipps-University Marburg, 35037 Marburg, Germany., Kronimus Y; Therapy Research in Neurogeriatrics, Center for Translational Neuro- and Behavioral Sciences, University of Duisburg-Essen, University Hospital Essen, 45147 Essen, Germany.; Department for Neurology, Philipps-University Marburg, 35037 Marburg, Germany., Burg-Roderfeld M; Department of Chemistry and Biology, Fresenius University of Applied Sciences, 65510 Idstein, Germany., van der Wurp H; Therapy Research in Neurogeriatrics, Center for Translational Neuro- and Behavioral Sciences, University of Duisburg-Essen, University Hospital Essen, 45147 Essen, Germany.; Faculty of Statistics, TU Dortmund University, 44227 Dortmund, Germany., Willbold D; Institute of Physical Biology, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.; Institute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich, 52428 Jülich, Germany., Ziehm T; Institute of Physical Biology, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany., Dodel R; Therapy Research in Neurogeriatrics, Center for Translational Neuro- and Behavioral Sciences, University of Duisburg-Essen, University Hospital Essen, 45147 Essen, Germany.; Department for Neurology, Philipps-University Marburg, 35037 Marburg, Germany., Ross JA; Therapy Research in Neurogeriatrics, Center for Translational Neuro- and Behavioral Sciences, University of Duisburg-Essen, University Hospital Essen, 45147 Essen, Germany.

المصدر: Biomolecules [Biomolecules] 2023 Aug 25; Vol. 13 (9). Date of Electronic Publication: 2023 Aug 25.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

مواضيع طبية MeSH: alpha-Synuclein*/immunology , Parkinson Disease*/genetics , Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/genetics, Humans ; Autoantibodies ; Leucine ; Mutation

المؤلفون: Hagve M; Center for Translational Research in Aging & Longevity, Dept. Health and Kinesiology, Texas A&M University, College Station, TX, USA. Electronic address: m.hagve@ctral.org., Pereira SL; Abbott Nutrition, Research and Development, Columbus, OH, USA. Electronic address: suzette.pereira@abbott.com., Walker DK; Center for Translational Research in Aging & Longevity, Dept. Health and Kinesiology, Texas A&M University, College Station, TX, USA., Engelen MPKJ; Center for Translational Research in Aging & Longevity, Dept. Health and Kinesiology, Texas A&M University, College Station, TX, USA. Electronic address: mpkj.engelen@ctral.org., Deutz NEP; Center for Translational Research in Aging & Longevity, Dept. Health and Kinesiology, Texas A&M University, College Station, TX, USA. Electronic address: nep.deutz@ctral.org.

المصدر: Metabolism: clinical and experimental [Metabolism] 2024 Jul; Vol. 156, pp. 155920. Date of Electronic Publication: 2024 Apr 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 0375267 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8600 (Electronic) Linking ISSN: 00260495 NLM ISO Abbreviation: Metabolism Subsets: MEDLINE

مواضيع طبية MeSH: Leucine*/metabolism , Leucine*/pharmacology , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/therapeutic use , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/pharmacology , Valerates*/pharmacology, Humans ; Male ; Female ; Aged ; Prospective Studies ; Middle Aged ; Hyperlipidemias/drug therapy ; Hyperlipidemias/metabolism ; Keto Acids/metabolism ; Amino Acids, Branched-Chain/metabolism

المؤلفون: Ilieva NM; Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA., Hoffman EK; Pittsburgh Institute for Neurodegenerative Diseases, Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA., Ghalib MA; Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA., Greenamyre JT; Pittsburgh Institute for Neurodegenerative Diseases, Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA., De Miranda BR; Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA. Electronic address: BrianaDeMiranda@UABMC.edu.

المصدر: Neurobiology of disease [Neurobiol Dis] 2024 Jun 15; Vol. 196, pp. 106522. Date of Electronic Publication: 2024 May 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE

مواضيع طبية MeSH: Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/metabolism , Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/antagonists & inhibitors , Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/genetics , Reactive Oxygen Species*/metabolism, Animals ; Rats ; Trichloroethylene/toxicity ; Mitochondria/drug effects ; Mitochondria/metabolism ; Rotenone/toxicity ; Parkinson Disease/metabolism ; Parkinson Disease/prevention & control ; Paraquat/toxicity ; Dopaminergic Neurons/drug effects ; Dopaminergic Neurons/metabolism ; Dopaminergic Neurons/pathology ; Oxidative Stress/drug effects ; Humans ; Environmental Pollutants/toxicity ; Rats, Sprague-Dawley