المؤلفون: Sharma PK; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093-0652, U.S.A., Weng JH; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093-0652, U.S.A., Manschwetus JT; Department of Biochemistry, University of Kassel, Heinrich-Plett-Str. 40, 34132 Kassel, Hessen, Germany., Wu J; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093-0652, U.S.A., Ma W; Department of Physics, University of Vermont, Burlington, Vermont., Herberg FW; Department of Biochemistry, University of Kassel, Heinrich-Plett-Str. 40, 34132 Kassel, Hessen, Germany., Taylor SS; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093-0652, U.S.A.; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093-0652, U.S.A.

المصدر: The Biochemical journal [Biochem J] 2024 Feb 21; Vol. 481 (4), pp. 313-327.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE

مواضيع طبية MeSH: Protein Serine-Threonine Kinases*/metabolism , Leucine-Rich Repeat Proteins*, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/metabolism ; Protein Domains ; Mutation ; Peptides/metabolism ; Phosphorylation

المؤلفون: Ilieva NM; Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA., Hoffman EK; Pittsburgh Institute for Neurodegenerative Diseases, Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA., Ghalib MA; Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA., Greenamyre JT; Pittsburgh Institute for Neurodegenerative Diseases, Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA., De Miranda BR; Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA. Electronic address: BrianaDeMiranda@UABMC.edu.

المصدر: Neurobiology of disease [Neurobiol Dis] 2024 Jun 15; Vol. 196, pp. 106522. Date of Electronic Publication: 2024 May 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE

مواضيع طبية MeSH: Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/metabolism , Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/antagonists & inhibitors , Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/genetics , Reactive Oxygen Species*/metabolism, Animals ; Rats ; Trichloroethylene/toxicity ; Mitochondria/drug effects ; Mitochondria/metabolism ; Rotenone/toxicity ; Parkinson Disease/metabolism ; Parkinson Disease/prevention & control ; Paraquat/toxicity ; Dopaminergic Neurons/drug effects ; Dopaminergic Neurons/metabolism ; Dopaminergic Neurons/pathology ; Oxidative Stress/drug effects ; Humans ; Environmental Pollutants/toxicity ; Rats, Sprague-Dawley

المؤلفون: Gao L; Department of General Practice, Tianjin Union Medical Center, Tianjin, China., Gaurav R; Paris Brain Institute - ICM, INSERM U1127, CNRS UMR 7225, Pitié-Salpêtrière Hospital, Sorbonne Université, Paris, France. rahul.gaurav@icm-institute.org.; Movement Investigations and Therapeutics Team (MOV'IT), Paris Brain Institute - ICM, Paris, France. rahul.gaurav@icm-institute.org.; Center for NeuroImaging Research (CENIR), Paris Brain Institute - ICM, Hôpital Pitié-Salpêtrière, 47 Boulevard de l'Hôpital, 75013, Paris, France. rahul.gaurav@icm-institute.org., Ziegner P; Paris Brain Institute - ICM, INSERM U1127, CNRS UMR 7225, Pitié-Salpêtrière Hospital, Sorbonne Université, Paris, France.; Center for NeuroImaging Research (CENIR), Paris Brain Institute - ICM, Hôpital Pitié-Salpêtrière, 47 Boulevard de l'Hôpital, 75013, Paris, France.; Department of Neurology (H.J.), University Hospital of Heidelberg, Heidelberg, Germany., Ma J; Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China., Sun J; Department of Neurology, Center for Movement Disorders, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China., Chen J; Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China., Fang J; Department of Radiology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China., Fan Y; Department of Radiology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China., Bao Y; Department of Radiology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China., Zhang D; Department of Neurology, Center for Movement Disorders, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China., Chan P; Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China., Yang Q; Department of Radiology, Xuanwu Hospital of Capital Medical University, Beijing, China., Fan Z; Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA., Lehéricy S; Paris Brain Institute - ICM, INSERM U1127, CNRS UMR 7225, Pitié-Salpêtrière Hospital, Sorbonne Université, Paris, France. stephane.lehericy@upmc.fr.; Movement Investigations and Therapeutics Team (MOV'IT), Paris Brain Institute - ICM, Paris, France. stephane.lehericy@upmc.fr.; Center for NeuroImaging Research (CENIR), Paris Brain Institute - ICM, Hôpital Pitié-Salpêtrière, 47 Boulevard de l'Hôpital, 75013, Paris, France. stephane.lehericy@upmc.fr.; Department of Neuroradiology, Pitié-Salpêtrière Hospital, AP-HP, Paris, France. stephane.lehericy@upmc.fr., Wu T; Department of Neurology, Center for Movement Disorders, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. wutao69@gmail.com.; China National Clinical Research Center for Neurological Diseases, Beijing, China. wutao69@gmail.com.

المصدر: Scientific reports [Sci Rep] 2024 May 09; Vol. 14 (1), pp. 10621. Date of Electronic Publication: 2024 May 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/genetics , Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/metabolism , Melanins*/metabolism , Magnetic Resonance Imaging*/methods , Parkinson Disease*/genetics , Parkinson Disease*/diagnostic imaging , Parkinson Disease*/pathology , Parkinson Disease*/metabolism , Substantia Nigra*/diagnostic imaging , Substantia Nigra*/pathology , Substantia Nigra*/metabolism, Humans ; Male ; Female ; Middle Aged ; Aged ; Heterozygote ; Adult ; Case-Control Studies

المؤلفون: Kuwahara T; Department of Neuropathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Iwatsubo T; Department of Neuropathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

المصدر: Autophagy [Autophagy] 2024 Jul; Vol. 20 (7), pp. 1692-1693. Date of Electronic Publication: 2024 Mar 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265188 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8635 (Electronic) Linking ISSN: 15548627 NLM ISO Abbreviation: Autophagy Subsets: MEDLINE

مواضيع طبية MeSH: Lysosomes*/metabolism , Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/metabolism , Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/genetics, Humans ; Animals ; Stress, Physiological ; Parkinson Disease/metabolism ; Parkinson Disease/pathology ; Parkinson Disease/genetics

المؤلفون: An J; Neuroscience Graduate Program, Department of Biomedical Sciences, Ajou University School of Medicine, Suwon, Kyunggi-do 16499, Republic of Korea; Department of Pharmacology, Ajou University School of Medicine, Suwon, Kyunggi-do 16499, Republic of Korea; Center for Convergence Research of Neurological Disorders, Ajou University School of Medicine, Suwon, Kyunggi-do 16499, Republic of Korea., Yang H; Neuroscience Graduate Program, Department of Biomedical Sciences, Ajou University School of Medicine, Suwon, Kyunggi-do 16499, Republic of Korea; Department of Pharmacology, Ajou University School of Medicine, Suwon, Kyunggi-do 16499, Republic of Korea; Center for Convergence Research of Neurological Disorders, Ajou University School of Medicine, Suwon, Kyunggi-do 16499, Republic of Korea., Park SM; Neuroscience Graduate Program, Department of Biomedical Sciences, Ajou University School of Medicine, Suwon, Kyunggi-do 16499, Republic of Korea; Department of Pharmacology, Ajou University School of Medicine, Suwon, Kyunggi-do 16499, Republic of Korea; Center for Convergence Research of Neurological Disorders, Ajou University School of Medicine, Suwon, Kyunggi-do 16499, Republic of Korea., Chwae YJ; Department of Microbiology, Ajou University School of Medicine, Suwon, Kyunggi-do 16499, Republic of Korea., Joe EH; Neuroscience Graduate Program, Department of Biomedical Sciences, Ajou University School of Medicine, Suwon, Kyunggi-do 16499, Republic of Korea; Department of Pharmacology, Ajou University School of Medicine, Suwon, Kyunggi-do 16499, Republic of Korea; Center for Convergence Research of Neurological Disorders, Ajou University School of Medicine, Suwon, Kyunggi-do 16499, Republic of Korea. Electronic address: ehjoe@ajou.ac.kr.

المصدر: Neurobiology of disease [Neurobiol Dis] 2024 Jul; Vol. 197, pp. 106528. Date of Electronic Publication: 2024 May 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE

مواضيع طبية MeSH: Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/genetics , Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/metabolism , Exosomes*/metabolism , Exosomes*/genetics , Osteopontin*/metabolism , Osteopontin*/genetics , Brain Injuries*/metabolism , Brain Injuries*/genetics , Mutation* , Monocytes*/metabolism, Animals ; Mice ; Mice, Inbred C57BL ; Neurons/metabolism ; Neurons/pathology ; Male ; Astrocytes/metabolism

المؤلفون: Yuan Y; Duke Center for Neurodegeneration and Neurotheraputics, Duke University, Durham, NC, USA.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Li H; Duke Center for Neurodegeneration and Neurotheraputics, Duke University, Durham, NC, USA.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Sreeram K; Duke Center for Neurodegeneration and Neurotheraputics, Duke University, Durham, NC, USA.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Malankhanova T; Duke Center for Neurodegeneration and Neurotheraputics, Duke University, Durham, NC, USA.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Boddu R; Duke Center for Neurodegeneration and Neurotheraputics, Duke University, Durham, NC, USA.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Strader S; Duke Center for Neurodegeneration and Neurotheraputics, Duke University, Durham, NC, USA.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Chang A; Duke Center for Neurodegeneration and Neurotheraputics, Duke University, Durham, NC, USA.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Bryant N; Duke Center for Neurodegeneration and Neurotheraputics, Duke University, Durham, NC, USA.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., Yacoubian TA; Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA., Standaert DG; Department of Neurodegenerative Science, Van Andel Institute, Grand Rapids, MI, USA., Erb M; Department of Neurodegenerative Science, Van Andel Institute, Grand Rapids, MI, USA., Moore DJ; Department of Neurodegenerative Science, Van Andel Institute, Grand Rapids, MI, USA., Sanders LH; Duke Center for Neurodegeneration and Neurotheraputics, Duke University, Durham, NC, USA.; Department of Neurology, Duke University, Durham, NC, USA.; Department of Pathology, Duke University, Durham, NC, USA., Lutz MW; Department of Neurology, Duke University, Durham, NC, USA.; Department of Pathology, Duke University, Durham, NC, USA., Velmeshev D; Department of Neurobiology, Duke University, Durham, NC, USA., West AB; Duke Center for Neurodegeneration and Neurotheraputics, Duke University, Durham, NC, USA. Andrew.West@Duke.edu.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA. Andrew.West@Duke.edu.; Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA. Andrew.West@Duke.edu.; Department of Neurology, Duke University, Durham, NC, USA. Andrew.West@Duke.edu.; Department of Neurobiology, Duke University, Durham, NC, USA. Andrew.West@Duke.edu.

المصدر: Molecular neurodegeneration [Mol Neurodegener] 2024 Jun 11; Vol. 19 (1), pp. 47. Date of Electronic Publication: 2024 Jun 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Electronic Cited Medium: Internet ISSN: 1750-1326 (Electronic) Linking ISSN: 17501326 NLM ISO Abbreviation: Mol Neurodegener Subsets: MEDLINE

مواضيع طبية MeSH: Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/genetics , Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/metabolism , Parkinson Disease*/blood , Parkinson Disease*/metabolism, Animals ; Humans ; Mice ; Rats ; rab GTP-Binding Proteins/metabolism ; Inflammation/metabolism ; Female ; Phosphorylation ; Mice, Transgenic ; Male ; Middle Aged ; Aged ; Severity of Illness Index

المؤلفون: Kang J; Department of Neurology, Brigham and Women's Hospital, Boston, United States., Huang G; Department of Neurology, Brigham and Women's Hospital, Boston, United States., Ma L; Department of Neurology, Brigham and Women's Hospital, Boston, United States., Tong Y; Department of Neurology, Brigham and Women's Hospital, Boston, United States., Shahapal A; Department of Neurology, Brigham and Women's Hospital, Boston, United States., Chen P; Department of Neurology, Brigham and Women's Hospital, Boston, United States., Shen J; Department of Neurology, Brigham and Women's Hospital, Boston, United States.; Program in Neuroscience, Harvard Medical School, Boston, United States.

المصدر: ELife [Elife] 2024 Jun 10; Vol. 12. Date of Electronic Publication: 2024 Jun 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Dopaminergic Neurons*/metabolism , Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/genetics , Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/metabolism , Mice, Knockout* , Cell Survival*, Animals ; Mice ; Protein Serine-Threonine Kinases/metabolism ; Protein Serine-Threonine Kinases/genetics ; Parkinson Disease/genetics ; Parkinson Disease/metabolism ; Apoptosis

المؤلفون: Potdar C; Department of Biophysics, National Institute of Mental Health and Neurosciences, Institute of National Importance, Bengaluru, India., Jagtap S; Department of Biophysics, National Institute of Mental Health and Neurosciences, Institute of National Importance, Bengaluru, India., Singh K; Department of Biophysics, National Institute of Mental Health and Neurosciences, Institute of National Importance, Bengaluru, India., Yadav R; Department of Neurology, National Institute of Mental Health and Neurosciences, Institute of National Importance, Bengaluru, India., Pal PK; Department of Neurology, National Institute of Mental Health and Neurosciences, Institute of National Importance, Bengaluru, India., Datta I; Department of Biophysics, National Institute of Mental Health and Neurosciences, Institute of National Importance, Bengaluru, India.

المصدر: Stem cells and development [Stem Cells Dev] 2024 Jun; Vol. 33 (11-12), pp. 306-320. Date of Electronic Publication: 2024 Jun 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101197107 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-8534 (Electronic) Linking ISSN: 15473287 NLM ISO Abbreviation: Stem Cells Dev Subsets: MEDLINE

مواضيع طبية MeSH: Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/genetics , Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/metabolism , Hedgehog Proteins*/metabolism , Hedgehog Proteins*/genetics , Induced Pluripotent Stem Cells*/metabolism , Induced Pluripotent Stem Cells*/cytology , Dopaminergic Neurons*/metabolism , Patched-1 Receptor*/genetics , Patched-1 Receptor*/metabolism , Parkinson Disease*/genetics , Parkinson Disease*/metabolism , Parkinson Disease*/pathology , Zinc Finger Protein GLI1*/genetics , Zinc Finger Protein GLI1*/metabolism, Humans ; Smoothened Receptor/genetics ; Smoothened Receptor/metabolism ; rab GTP-Binding Proteins/genetics ; rab GTP-Binding Proteins/metabolism ; Cyclic AMP/metabolism ; Caveolin 1/genetics ; Caveolin 1/metabolism ; Mutation/genetics ; Calcium/metabolism ; Cell Differentiation/genetics ; Signal Transduction/genetics

المؤلفون: Wetzel A; Department of Pharmacology, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London, WC1N 1AX, UK.; Institute of Physiology, Medical Faculty, Otto-von-Guericke-University, 39120, Magdeburg, Germany., Lei SH; Department of Pharmacology, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London, WC1N 1AX, UK., Liu T; Department of Pharmacology, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London, WC1N 1AX, UK., Hughes MP; Department of Pharmacology, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London, WC1N 1AX, UK., Peng Y; Department of Pharmacology, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London, WC1N 1AX, UK., McKay T; Department of Life Sciences, Dalton Building, Manchester Metropolitan University, Chester Street, Manchester, M1 5GD, UK., Waddington SN; Gene Transfer Technology Group, University College London, 86-96 Chenies Mews, London, WC1E 6HXZ, UK.; Wits/SAMRC Antiviral Gene Therapy Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Grannò S; Department of Pharmacology, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London, WC1N 1AX, UK.; Division of Neurosurgery, Department of Clinical Neurosciences, Geneva University Hospitals, Rue Gabrielle-Perret Gentil 4, 1205, Geneva, Switzerland., Rahim AA; Department of Pharmacology, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London, WC1N 1AX, UK., Harvey K; Department of Pharmacology, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London, WC1N 1AX, UK. kirsten.harvey@ucl.ac.uk.

المصدر: Scientific reports [Sci Rep] 2024 May 29; Vol. 14 (1), pp. 12393. Date of Electronic Publication: 2024 May 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/genetics , Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/metabolism , NFATC Transcription Factors*/metabolism , NFATC Transcription Factors*/genetics , Parkinson Disease*/genetics , Parkinson Disease*/metabolism , Parkinson Disease*/pathology , Wnt Signaling Pathway* , Disease Models, Animal*, Animals ; Male ; Mice ; Female ; Gene Knock-In Techniques ; Mice, Knockout ; Neurons/metabolism ; Brain/metabolism ; Brain/pathology ; Mutation ; Humans

المؤلفون: Fang P; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA. phoen.f@gmail.com., Yu LW; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Espey H; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Agirman G; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Kazmi SA; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Li K; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA.; Research Division of Immunology, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Deng Y; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Department of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China., Lee J; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Hrncir H; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Romero-Lopez A; UCLA Goodman-Luskin Microbiome Center, Vatche and Tamar Manoukian Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine, Los Angeles, CA, 90095, USA., Arnold AP; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Hsiao EY; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA. ehsiao@g.ucla.edu.; UCLA Goodman-Luskin Microbiome Center, Vatche and Tamar Manoukian Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine, Los Angeles, CA, 90095, USA. ehsiao@g.ucla.edu.; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, 90095, USA. ehsiao@g.ucla.edu.

المصدر: Communications biology [Commun Biol] 2024 May 15; Vol. 7 (1), pp. 570. Date of Electronic Publication: 2024 May 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

مواضيع طبية MeSH: Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/genetics , Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/metabolism , Parkinson Disease*/genetics , Parkinson Disease*/metabolism , Parkinson Disease*/pathology, Animals ; Mice ; Male ; Female ; Endophenotypes ; alpha-Synuclein/metabolism ; alpha-Synuclein/genetics ; Prodromal Symptoms ; Disease Models, Animal ; Mice, Transgenic ; Humans ; Sex Factors ; Inflammation/metabolism ; Inflammation/genetics ; Mice, Inbred C57BL ; Sex Characteristics