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1دورية أكاديمية
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المؤلفون: Aftab Alam, Abuzer Ali, Mohd Amir, Farhan Jalees Ahmad, Wasim Ahmad, Niyaz Ahmad, Rizwan Ahmad
المصدر: Saudi Journal of Biological Sciences, Vol 27, Iss 1, Pp 500-517 (2020)
Saudi Journal of Biological Sciencesمصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, Naringenin, Antioxidant, medicine.medical_treatment, MCAO-oxidative stress, CS, chitosan, Pharmacology, UHPLC-MS/MS-pharmacokinetic, 01 natural sciences, chemistry.chemical_compound, TBARS, thiobarbituric acid reactive substances, lcsh:QH301-705.5, Q-TOF, quadrupole time of flight, Tmax, time to Cmax, MQC, middle quality control, ESI, electrospray ionization, TEM, transmission electron microscope, CLSM, confocal laser scanning microscopy, Cerebral ischemia, LOD, lower limit of detection, NRG, naringenin, Kel, elimination rate constant, Toxicity, BA, bioavailability, General Agricultural and Biological Sciences, Quercetin, LLOQ QC, lower limit of quantification for quality control, SEM, scanning electron microscope, Ischemia, LLOQ, lower limit of quantification, AUC, area under curve, UHPLC-MS/MS, ultra high performance liquid chromatography mass spectroscopy and mass spectroscopy, PK, pharmacokinetic, Article, Cmax, maximum plasma concentration, 03 medical and health sciences, NE, nanoemulsion, Mucoadhesive-chitosan-based-nanoemulsion-gel, medicine, Potency, MCAO, middle cerebral artery occlusion, ComputingMethodologies_COMPUTERGRAPHICS, ANOVA., analysis of variance, LOQ, lower limit of quantitation, PDI, polydispersity index, t½, half-life, medicine.disease, Bioavailability, 030104 developmental biology, LLE, liquid–liquid extraction, chemistry, lcsh:Biology (General), HQC, high quality control, Nasal administration, LQC, low quality control, 010606 plant biology & botany
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbf9305501d6bea3502fb47e997e300
http://www.sciencedirect.com/science/article/pii/S1319562X19302402 -
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المؤلفون: Wenjuan Hu, Bo Tan, Lu Chang, Yuanchao Xie, Jia Liu, Chang-Qiang Ke, Jingshan Shen
المصدر: Journal of Pharmaceutical and Biomedical Analysis
مصطلحات موضوعية: Male, Clinical Biochemistry, Pharmaceutical Science, 01 natural sciences, PPT, protein precipitation, Analytical Chemistry, chemistry.chemical_compound, Mice, FDA, United States Federal Drug Administration, Tandem Mass Spectrometry, Recovery, Drug Discovery, Nucleotide, Prodrugs, ATNs, active triphosphate nucleotide metabolites, IS, internal standard, RDV, remdesivir, Spectroscopy, FA, formic acid, chemistry.chemical_classification, Aqueous solution, Alanine, ESI, electrospray ionization, Prodrug, LLE, liquid-liquid extraction, Liver, COVID 19, coronavirus disease 2019, RSDs, relative standard deviations, RMP, remdesivir monophosphate, Stability, NH4Ac, ammonium acetate, LLOQ, lower limit of quantitation, Bioanalysis, ATP, adenosine triphosphate, Formic acid, UPLC-MS/MS, ultra-performance liquid chromatography coupled triple-quadrupole mass spectrometry, Electrospray ionization, KD, equilibrium dissociation constant, Remdesivir, Mass spectrometry, Antiviral Agents, Nucleotide triphosphate, Article, LC–MS/MS, FT-ICR MS, fourier transform ion cyclotron resonance mass spectrometry, RTP, remdesivir nucleotide triphosphate, Animals, Humans, AgNO3, silver nitrate, RdRp, RNA-dependent RNA polymerases, TCEP, tris (2 carboxyethyl) phosphine hydrochloride, Active metabolite, ComputingMethodologies_COMPUTERGRAPHICS, Chromatography, 010405 organic chemistry, Nucleotide monophosphate, 010401 analytical chemistry, SPE, solid-phase extraction, COVID-19, DTNB, 55′ dithiobis (2-nitrobenzoic acid), ACN, acetonitrile, Adenosine Monophosphate, 0104 chemical sciences, COVID-19 Drug Treatment, BNPP, bis (p-nitrophenyl) phosphate, QC, quality control, RN, remdesivir nucleoside, chemistry, SARS CoV 2, severe acute respiratory coronavirus 2, MeOH, methanol, UTP, uridine triphosphate, HSA, human serum albumin, Chromatography, Liquid
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المؤلفون: Ginevra Giacomello, Maria Kristina Parr, Andreas Scholten
المصدر: Journal of Pharmaceutical and Biomedical Analysis
مصطلحات موضوعية: MALDI-MS, (Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry), ECLIA, (ElectroChemiLuminescence ImmunoAssay), 01 natural sciences, Analytical Chemistry, QCM, (Quartz-Crystal Microbalance), Drug Discovery, sAA, (salivary alpha-amylase), Spectroscopy, Immunoassay, AIE, (Aggregation-induced Emission), PPY, (Polypyrrole), SPME, (Solid-Phase MicroExtraction), LLE, (Liquid-Liquid Extraction), AA, (alpha-amylase), Mass spectrometric, AuNPs, (Gold NanoParticles), AED, (androstenedione), rGO, (reduced Graphene Oxide), SPCE, (Screen-Printed Carbon Electrodes), Pneumonia, Viral, FOSPR, (Fiber Optic Surface Plasmon Resonance), MHPG, (3-Methoxy-4-hydroxyphenylglycol), Article, Specimen Handling, n.s., (not specified), HPLC, (High Performance Liquid Chromatography), Humans, TR-IFMA, (Time-Resolved Immuno-Fluorometric Assay), Saliva, Mass spectrometry, 010405 organic chemistry, Vis, (Visible detector), 010401 analytical chemistry, NU, (Novo Unit), Biomarker, CNT, (multiwall Carbon NanoTubes), LC, (Liquid Chromatography), CNF-SPE, (Carbon NanoFiber Electrodes), IIM, (Intensity Interrogation Mode), 0104 chemical sciences, DHEA, (dehydroepiandrosterone), SPR, (Surface Plasmon Resonance), AIM, (Angular Interrogation Mode), CV, (Cyclic Voltammetry), n.c., (not calculated), UHPLC, (Ultra-High-Performance Liquid Chromatography), MEPS, (MicroExtraction by Packed Sorbent), UV, (UltraViolet detector), LSPR, (Localized Surface Plasmon Resonance), Biomarkers, MIP, (Molecularly Imprinted Polymer), Clinical Biochemistry, Pharmaceutical Science, Bioinformatics, PPAuNPs, (Polyaniline Protected gold Nanoparticles), DHEA-S, (dehydroepiandrosterone-sulfate), DPV, (Differential Pulse Voltammetry), XLC, (eXtraction Liquid Chromatography), FIA, (Flow Injection Analysis), MS/MS, (tandem mass spectrometry), POC, (Point Of Care), FO, (Fiber Optic), Biomarker Analysis, APCI, (Atmospheric-Pressure Chemical Ionization), c-Mab, (Monoclonal Antibody), HRV-SCort, (Heart Rate Variability combined with Salivary Cortisol), ESI, (Electrospray Ionization), Chromatography, MD, (MaltoDextrin), Chemistry, SPRS, (Surface Plasmon Resonance Spectroscopy), PEG, (polyethylene glycol), iCIEF, (Imaging detection Capillary Isoelectric Focusing), Stress marker, Point of care device, Biomarker (medicine), Coronavirus Infections, IA, (ImmunoAssay), Coronavirus disease 2019 (COVID-19), 17−OHP, (17α-hydroxyprogesterone), SPE, (Solid-Phase Extraction), Secretory Immunoglobulin A, DAD, (Diode Array Detection), IL-DLLME, (Ionic Liquid Dispersive Liquid-Liquid MicroExtraction), LMR, (Lossy Mode Resonance), DLLME, (Dispersive Liquid-Liquid MicroExtraction), SWV, (Square Wave Voltammetry), PIT, (Photochemical Immobilization Technique), Pandemics, CL, (ChemiLuminescence assay), ComputingMethodologies_COMPUTERGRAPHICS, LFIA, (Lateral Flow ImmunoAssay), COVID-19, HMP, (2-Hydrazino-1-MethylPyridine), Review article, Psychological stress, CLIA, (ChemiLuminescence ImmunoAssay), Stress, Psychological
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المؤلفون: Natalie Z.M. Homer, Francine Durocher, Ruth Andrew, Nina Denver, Brigitte Poirier, Caroline Diorio, Mélissa Pelletier, Sofia Laforest, Brian R. Walker, André Tchernof, Sébastien Nguyen
المصدر: Laforest, S, Pelletier, M, Denver, N, Poirier, B, Nguyen, S, Walker, B R, Durocher, F, Homer, N Z M, Diorio, C, Tchernof, A & Andrew, R 2019, ' Simultaneous quantification of estrogens and glucocorticoids in human adipose tissue by liquid-chromatography-tandem mass spectrometry ', Journal of Steroid Biochemistry and Molecular Biology, vol. 195, 105476 . https://doi.org/10.1016/j.jsbmb.2019.105476
The Journal of Steroid Biochemistry and Molecular Biologyمصطلحات موضوعية: 0301 basic medicine, HPLC, High-performance liquid chromatography, MPPZ, 1-(2,4-dinitro-phenyl)-4,4-dimethylpiperazinium, Hydrocortisone, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Adipose, Clinical Biochemistry, Adipose tissue, 13C3-E2, 2,3,4-[13C3]-17β-estradiol, Biochemistry, RSD, Relative standard deviation, Cortisol, DCM, Dichloromethane, SPE, Solid-phase extraction, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Tandem Mass Spectrometry, Liquid chromatography–mass spectrometry, E2, Estradiol, LLE, Liquid-liquid extraction, LOQ, Limit of quantitation, Receptor, LOD, Limit of detection, chemistry.chemical_classification, Estradiol, Chemistry, FA, Formic acid, EtOH, Ethanol, IS, Internal standards, LC–MS/MS, Liquid chromatography-tandem mass spectrometry, OFN, Oxygen-free nitrogen, E, Cortisone, Derivatization, 3. Good health, Adipose Tissue, Et2O, Diethyl ether, 030220 oncology & carcinogenesis, Molecular Medicine, lipids (amino acids, peptides, and proteins), Female, hormones, hormone substitutes, and hormone antagonists, inorganic chemicals, GC–MS/MS, Gas chromatography-tandem mass spectrometry, Spectrometry, Mass, Electrospray Ionization, RM, Estrone, E1, Estrone, UHPLC, Ultra-high-performance liquid chromatography, Breast Neoplasms, Article, Steroid, 03 medical and health sciences, EtOAc, Ethyl acetate, medicine, Humans, D4-F, 9,11,12,12-[2H4]-cortisol, Glucocorticoids, Molecular Biology, Detection limit, 13C3-E1, 2,3,4-[13C3]-estrone, Chromatography, organic chemicals, RME, Relative mean error, MTBE, Methyl t-butyl ether, PPZ, 1-(2,4-dinitro-5-fluorophenyl)-4-methylpiperazine, technology, industry, and agriculture, SNR, Signal-to-noise ratio, Estrogens, Cell Biology, QR, Cortisone, MeOH, Methanol, 030104 developmental biology, Enzyme, ESI, Electrospray ionization, MRM, Multiple reaction monitoring, Chromatography, Liquid
وصف الملف: application/pdf
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المؤلفون: Carmina Candela, Manuela Contin, Susan Mohamed, Roberto Riva
المصدر: Practical Laboratory Medicine, Vol 10, Iss C, Pp 15-20 (2018)
Practical Laboratory Medicineمصطلحات موضوعية: AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, VPA, valproic acid, CBZ, carbamazepine, Antiepileptic drugs, Clinical Biochemistry, PHT, phenytoin, Clinical pharmacokinetics, LLOQ, lower limit of quantification, Pharmacology, Perampanel, 030226 pharmacology & pharmacy, Article, LLOD, lower limit of detection, lcsh:Chemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Hplc fluorescence, TDM, therapeutic drug monitoring, medicine, Sample preparation, IS, internal standard, MS/MS, tandem mass spectrometer, Acetonitrile, lcsh:R5-920, Epilepsy, Chromatography, Radiological and Ultrasound Technology, medicine.diagnostic_test, AED, antiepileptic drug, Plasma, Fluorescence, LLE, liquid-liquid extraction, QC, quality control, lcsh:QD1-999, chemistry, Therapeutic drug monitoring, OXC, oxcarbazepine, PER, perampanel, HPLC-F, high performance liquid chromatography-fluorescence detector, MIR, mirtazapine, lcsh:Medicine (General), Sodium acetate, HPLC-F, 030217 neurology & neurosurgery
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المؤلفون: Janak L. Pathak, Chang Y. Chung, Shi Yu, Nasir Jalal, Austin R. Surendranath
المصدر: Toxicology Reports, Vol 5, Iss, Pp 76-84 (2018)
Toxicology Reportsمصطلحات موضوعية: LLE, liquid/liquid extraction, 0301 basic medicine, MAPK/ERK pathway, endocrine system, DNA damage, Health, Toxicology and Mutagenesis, Cell, Ca2+ homeostasis, Glucuronidation, EFSA, European Food Safety Authority, 010501 environmental sciences, Toxicology, medicine.disease_cause, 01 natural sciences, Article, 03 medical and health sciences, Sulfation, IGF1R, lcsh:RA1190-1270, SPCA1 inhibition, ELISA, enzyme linked immunosorbent assay, IGF1R, insulin-like growth factor 1 receptor, medicine, SPCA1, secretory pathway calcium ATPase1, ComputingMethodologies_COMPUTERGRAPHICS, Cancer, 0105 earth and related environmental sciences, Insulin-like growth factor 1 receptor, lcsh:Toxicology. Poisons, Chemistry, urogenital system, DES, diethyl stilbesterol, BISPHENOL A (BPA) CCID: 6623, FAO/WHO, Food and Agricultural Organization/World Health Organization, Cell biology, 030104 developmental biology, medicine.anatomical_structure, MS, mass spectrometry, SPE, solid phase extraction, HPLC, high-performance liquid chromatography, FDA, Food and Drugs Administration, GC–MS, gas chromatography–mass spectrometry, Signal transduction, Bisphenol A (BPA), Carcinogenesis, Mutations, hormones, hormone substitutes, and hormone antagonists
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8دورية أكاديمية
المؤلفون: Barek, J., Cvačka, J., Muck, A., Quaiserová, V., Zima, J.
المصدر: Fresenius' Journal of Analytical Chemistry. April 2001 369(7-8):556-562
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المؤلفون: Timothy G. Dinan, Conall R. Strain, Catherine Stanton, Fiona Fouhy, Gerard Clarke, Anna V. Golubeva, Sofia Cussotto, Alexander V. Zhdanov, Jacinta Walsh, John F. Cryan, Brendan T. Griffin, Niall P. Hyland
المصدر: EBioMedicine, Vol 66, Iss, Pp 103307-(2021)
EBioMedicineمصطلحات موضوعية: Male, 0301 basic medicine, Olanzapine, Medicine (General), Research paper, Bioavailability, medicine.medical_treatment, I.S., internal standard, HPLC, High performance liquid chromatography, Administration, Oral, MRT, mean residual time, Gut flora, Pharmacology, 5-HT, Serotonin (5-hydroxytryptamine), law.invention, MDR-1, multi-drug resistance protein 1, Antipsychotic, Feces, Probiotic, 0302 clinical medicine, Oral administration, law, CYP, RT-qPCR, reverse-transcriptase quantitative polymerase chain reaction, AUMC0-8h, area under the first-moment curve from time 0→ 8 hours after drug administered, Chromatography, High Pressure Liquid, Diversity, Molecular Structure, biology, CYP, Cytochrome p450 superfamily of enzymes, Biodiversity, General Medicine, LLE, liquid-liquid extraction, Anti-Bacterial Agents, RISP, risperidone, 030220 oncology & carcinogenesis, Medicine, Drug Monitoring, Selective Serotonin Reuptake Inhibitors, medicine.drug, % CV, Percentage coefficient of variation, Biological Availability, 5-HT-GLU, Serotonin β-D-Glucuronide, digestive system, General Biochemistry, Genetics and Molecular Biology, Cmax, maximum plasma concentration, 03 medical and health sciences, R5-920, Pharmacokinetics, OLZ, olanzapine, BCS, biopharmaceutical classification system, medicine, Animals, Microbiome, AUC0-8h, area under the plasma concentration vs time curve from time 0→ 8 hours after drug administered, business.industry, Probiotics, biology.organism_classification, Gastrointestinal Microbiome, Rats, GF, germ-free, 030104 developmental biology, UGT, Uridine 5′-diphospho-glucuronosyltransferase, business, Tmax, time taken to reach maximum plasma concentration
وصف الملف: application/pdf
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المؤلفون: Maria Assunta Acquavia, Raffaella Pascale, Luca Foti, Laura Scrano, Antonia Nicolò, Vincenzo Brancaleone, Giuseppe Martelli, Tommaso R. I. Cataldi, Giuliana Bianco
المصدر: Talanta
مصطلحات موضوعية: HILIC, hydrophilic interaction liquid chromatography, PIs, protease inhibitors, RSD, relative standard deviation, Review, CE, capillary electrophoresis, MSI, MALDI-MS Imaging, 02 engineering and technology, Chemical Fractionation, Biological matrices, Pharmacology, CSF, cerebrospinal fluid, 01 natural sciences, Analytical Chemistry, Drug detection, MRM, Muliple Reaction Monitoring, OSP, oseltamivir phosphate, Tandem Mass Spectrometry, TDM, therapeutic drug monitoring, Ph. Eur, European Pharmacopoeia, Chromatography, High Pressure Liquid, ESI, electrospray ionization, LC, liquid chromatography, Chemistry, FL, fluorescence, Antivirals, 021001 nanoscience & nanotechnology, RdRpIs, RNA polymerase inhibitors, LLE, liquid-liquid extraction, Err, absolute value of the relative error, 0210 nano-technology, Q-MSI, quantitative MALDI-MS Imaging, RE, relative error, SDS, sodium dodecyl sulfate, Coronavirus disease 2019 (COVID-19), MALDI, matrix-assisted laser desorption/ionization, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), PSA, primary-secondary amine, Liquid chromatography, HLB, hydrophilic-lipophilic balance, LLOQ, lower limit of quantification, Q, QuEChERS, TCA, trichloroacetic acid, Quechers, Antiviral Agents, CHCA, α-cyano-4-hydroxycinnamic acid, BeWos, human placental choriocarcinoma trophobplast cells, Capillary electrophoresis, Pharmacokinetics, Analytical methods, UAE, ultrasound assisted extraction, PMA, phosphomolybdic acid, Biological fluids, Animals, Humans, ADME, adsorption, distribution, metabolism, and elimination, ICH, International Conference on Harmonization, Pandemics, SRM, Selected Reaction Monitoring, PBA, phenylboronic acid, LOQ, limit of quantification, PBMCs, peripheral blood mononuclear cells, UHPLC, ultra-high performance liquid chromatography, LOD, limit of detection, Mass spectrometry, SARS-CoV-2, SPE, solid-phase extraction, 010401 analytical chemistry, d-SPE, dispersive-sold-phase extraction, COVID-19, CV, coefficient of variation, MTBE, methyltertbutyl ether, ACN, acetonitrile, FDA, Food and Drug Administration, COVID-19 Drug Treatment, 0104 chemical sciences, MCX, mixed-mode cationic exchange, QC, quality control, Clinical trial, NRTIs, nucleoside reverse transcriptase inhibitors, PP, protein precipitation, MS, mass spectrometry, MLC, micellar liquid chromatography, CRMs, certified reference materials, DEV, deviation from nominal concentration value, EMA, European Medicines Agency, AD, absolute deviation, DHB, 2,5-dihydroxybenzoic acid